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1. Woman's eyesight saved by cutting-edge test after mystery infection

   Tue, 29 Apr 2025 23:06:31 -0000

   After years of suffering, a cutting-edge test diagnosed Ellie Irwin with a rare bacterial infection.

2. NHS trust admits failures led to teenager's death

   Wed, 30 Apr 2025 05:21:49 -0000

   Staff were tasked with giving one-to-one care to Elise Sebastian, an inquest hears.

3. Male workers should be able to carry out mammograms, experts say

   Tue, 29 Apr 2025 08:13:22 -0000

   The Society of Radiographers says allowing men to do mammograms would reduce staff shortages.

4. Milkshakes and lattes could be covered by sugar tax

   Tue, 29 Apr 2025 08:09:02 -0000

   The tax would be applied to manufacturers of milk-based drinks and dairy-based substitutes, under the plans.

5. Prescription charges frozen in England

   Mon, 28 Apr 2025 14:53:54 -0000

   The charge for a single item will remain at £9.90 in 2025-26, the government has announced.

6. Ultra-processed foods may be linked to early death

   Mon, 28 Apr 2025 12:47:47 -0000

   UPFs, such as crisps, biscuits, ice cream, hot dogs and fizzy drinks, are increasingly common in diets worldwide.

7. Urgent care worse than pre-pandemic, think tank says

   Sun, 27 Apr 2025 23:02:21 -0000

   The Health Foundation argues that the NHS was "in distress" this winter with A&E waiting times reaching a record high.

8. 'My peanut allergy nearly killed me - now I eat them every day for breakfast'

   Wed, 23 Apr 2025 23:03:24 -0000

   Just a few years ago, Chris Brookes-Smith could have died from eating peanuts - but taking part in a clinical trial has changed his life.

9. 'Why I want an IVF baby to screen out gene that made me go blind'

   Sun, 20 Apr 2025 00:04:43 -0000

   Blind influencer Lucy Edwards on choosing IVF which will screen out the gene that made her who she is.

10. Plan for GPs to keep millions out of hospital

    Thu, 17 Apr 2025 09:48:37 -0000

    GPs will work more closely with specialists to support patients closer to home, the government says.

11. Disposable vape use falling in UK ahead of ban

    Wed, 16 Apr 2025 06:23:05 -0000

    The number of people vaping in the UK has stalled, while disposable vape usage has fallen, a study suggests.

12. WHO agrees legally binding pandemic treaty

    Wed, 16 Apr 2025 12:40:46 -0000

    The agreement is designed to ensure more cooperation between nations in the event of another pandemic.

13. Doctors in two end-of-life cases can be named

    Wed, 16 Apr 2025 13:22:54 -0000

    Those involved in caring for Isaiah Haastrup and Zainab Abbasi can be named, the Supreme Court rules.

14. North Scotland among highest rates of Huntington's

    Wed, 16 Apr 2025 07:59:26 -0000

    The statistics are five times higher than the world figure, a University of Aberdeen study says.

15. Why men are so unhealthy - and what can be done

    Sun, 06 Apr 2025 00:40:30 -0000

    Men are more likely to die prematurely than women - and worse at seeking care when they need it.

16. What goes on inside toddlers' brains?

    Thu, 10 Apr 2025 23:13:02 -0000

    A unique study is tracking the development of hundreds of babies whose parents have also been studied since birth.

17. 'My long Covid turned out to be terminal cancer'

    Mon, 07 Apr 2025 10:39:19 -0000

    Olivia Knowles noticed something "wasn't quite correct" while competing in an ironman competition.

18. Woman contacted by stranger on DNA site - and the truth about her birth unravelled

    Sat, 05 Apr 2025 00:20:36 -0000

    An NHS trust has paid compensation after a woman, now in her 70s, discovered she had been swapped at birth.

19. 'I could live 30 years but plan to die': How assisted dying law is dividing Canadians

    Fri, 04 Apr 2025 01:24:38 -0000

    BBC News reports on assisted dying in Canada, where some say it's now easier to choose to die than get support to live

20. Are my braids doing more harm than good?

    Sun, 30 Mar 2025 00:03:42 -0000

    Research suggests the synthetic hair used for braiding could be bad for you - but will that stop women using it?

21. California man invites BBC to witness his death as MPs debate assisted dying

    Thu, 03 Apr 2025 21:10:48 -0000

    Wayne Hawkins believes terminally ill people should be able to die when they choose, but others in the state disagree.

22. 'I fear I'll be dead before I get justice for my son'

    Sat, 29 Mar 2025 09:56:44 -0000

    Tony Summers' son Paul was diagnosed with HIV and Hepatitis C and died in 2008 aged 44.

23. Doctor 'betrayed' over son's death at her hospital

    Thu, 27 Mar 2025 17:31:46 -0000

    Deborah Burns says she is unable to return to work at the hospital after the death of her son, William Hewes.

24. Baby slings unsafe for hands-free feeding, charities warn

    Wed, 26 Mar 2025 16:12:49 -0000

    Parenting charities, including the NCT, have updated their advice saying slings and carriers are unsafe for feeding.

25. Fake £4m Xanax drug gang boss jailed

    Thu, 27 Mar 2025 16:35:28 -0000

    The gang, managed from Thailand, produced 11 million pills in the West Midlands to be sold online.

26. Baby deaths trust claimed £2m 'good care' payments

    Wed, 26 Mar 2025 06:19:57 -0000

    An NHS trust criticised over a baby's death claimed money for providing good care, the BBC can reveal.

27. Fertility patients sold unproven add-ons, HFEA says

    Wed, 26 Mar 2025 10:25:25 -0000

    Despite little proof add-ons help, many IVF clinics offer them, the UK's fertility regulator warns.

28. Hancock criticises 'wholly naive' Covid inquiry

    Wed, 19 Mar 2025 17:14:53 -0000

    The former health secretary was giving evidence about medical equipment deals during the pandemic.

29. Mone accuses Covid inquiry of 'cover-up'

    Thu, 13 Mar 2025 19:10:36 -0000

    She says husband Doug Barrowman and her are targets of a "politically motivated witch hunt".

30. Michael Gove denies trying to circumvent Dyson ventilator checks

    Tue, 11 Mar 2025 12:29:20 -0000

    Former cabinet minister says it would be ludicrous to suggest he tried to shortcut safety checks in the pandemic.

31. How does the Covid inquiry work?

    Thu, 16 Jan 2025 09:58:17 -0000

    The inquiry has heard from politicians, civil servants, public health experts and bereaved families.

32. Michelle Mone-linked PPE firm evidence to be heard in private

    Wed, 26 Feb 2025 00:00:16 -0000

    Covid inquiry says hearings into the firm, led by Michelle Mone's husband, must be held in closed session.

33. Large UK-wide pandemic preparedness tests planned this year

    Thu, 16 Jan 2025 16:36:01 -0000

    The stress test will involve thousands of people to help the UK prepare for potential future threats.

34. Families failed by Covid jabs tell inquiry of pain

    Wed, 15 Jan 2025 18:39:40 -0000

    They said there was no support after the death and harm suffered by their loved ones.

35. NHS hours from PPE running out in Covid - Hancock

    Thu, 21 Nov 2024 16:58:34 -0000

    Former health secretary tells inquiry some healthcare settings did run out - "and it was awful".

36. Covid inquiry told Treasury blocked NHS bed request

    Mon, 11 Nov 2024 18:06:48 -0000

    NHS England chief executive Amanda Pritchard says the decision, in July 2020, was very disappointing.

37. Covid inquiry told top NHS doctor was terrified

    Thu, 07 Nov 2024 17:34:34 -0000

    Sir Stephen Powis says points-based tool was drawn up should need to prioritise patients have arisen.

38. How close were hospitals to collapse in Covid?

    Mon, 28 Oct 2024 00:06:04 -0000

    The Covid inquiry restarts its live hearings this week, after senior staff in the NHS revealed just how close some hospitals were to collapse

39. Covid inquiry told of trust do-not-resuscitate rule

    Thu, 10 Oct 2024 16:54:11 -0000

    Patients' families were “horrified but not surprised” when told the blanket policy had been in place.

40. We were not treated as parents, Covid inquiry told

    Mon, 07 Oct 2024 14:11:38 -0000

    Mum of premature twins says rigid restrictions on birthing wards during Covid were traumatic.

41. Covid ambulance crews faced 'crucial PPE delays'

    Tue, 01 Oct 2024 14:39:04 -0000

    Crews say they faced crucial delays trying to save dying patients because of the time it took to put on equipment.

42. Covid was like a daily terror attack, doctor tells inquiry

    Thu, 26 Sep 2024 14:06:37 -0000

    Covid inquiry hears harrowing testimony from ex-adviser in emergency preparedness at NHS England.

43. Covid inquiry rejects clinicians’ anonymity plea

    Thu, 26 Sep 2024 00:11:07 -0000

    The UK Health Security Agency argued naming the junior officials could put them at risk of abuse.

44. Warning tax rises could force care homes to close

    Thu, 31 Oct 2024 13:50:35 -0000

    Social care providers say the sector is in "unprecedented danger" without more funding.

45. High-grade masks evidence weak, Covid inquiry told

    Thu, 19 Sep 2024 11:39:28 -0000

    UKHSA's Prof Susan Hopkins said respirator masks may have worked no better than thin surgical masks.

46. Nurses bore the brunt of Covid, ex-chief nurse says

    Tue, 17 Sep 2024 15:58:13 -0000

    Dame Ruth May tells the Covid inquiry nurses struggled with low staffing levels and difficulties accessing protective equipment.

47. Labour's plan for benefits throws up a bigger dilemma

    Mon, 17 Mar 2025 06:06:29 -0000

    The debate has sparked a wider dilemma about the broader purpose of welfare

48. First place in British Isles set to approve right to die

    Tue, 25 Feb 2025 13:02:21 -0000

    Laws in the Isle of Man to let terminally ill adults end their own lives are in the last stages of debate.

49. Generation K: The disturbing rise of ketamine abuse among young people

    Tue, 25 Feb 2025 06:00:36 -0000

    Increasing numbers of young people are using the drug, experts say. The health impacts can be catastrophic.

50. Assisted dying bill: What is in proposed law?

    Fri, 29 Nov 2024 15:30:26 -0000

    The proposed law would allow some terminally ill adults to end their own lives. But there are requirements.

51. 'My first cervical screening was over before I knew it'

    Sun, 02 Feb 2025 01:06:51 -0000

    The BBC speaks to six people about their first cervical screening, and what they wish they'd known beforehand.

52. How are the vaping rules changing?

    Tue, 05 Nov 2024 17:06:32 -0000

    Marketing rules will be stricter, nicotine vapes will be taxed and disposable vapes will be banned.

53. Is the system letting down people who were harmed by Covid vaccines?

    Wed, 23 Oct 2024 05:48:59 -0000

    People affected by rare blood clots say they feel they have been airbrushed out of the pandemic.

54. How will weight-loss drugs change our relationship with food?

    Sat, 19 Oct 2024 03:10:13 -0000

    The rise of these treatments has major implications for how we think about obesity, says James Gallagher.

55. NHS needs better plan around weight loss jabs, warn experts

    Wed, 16 Oct 2024 07:27:18 -0000

    Experts call for an urgent review of obesity treatment services amid booming demand for weight loss jabs.

56. How many of us will end up being diagnosed with ADHD?

    Sun, 15 Sep 2024 00:36:40 -0000

    Experts suggest that the number of people with ADHD is actually going to remain steady.

57. The junior doctors' strikes may be over. But is trouble ahead?

    Fri, 02 Aug 2024 00:43:02 -0000

    The end of the pay dispute sounded too good to be true. And now some are wondering if it might be.

58. Why we might never know the truth about ultra-processed foods

    Sat, 27 Jul 2024 23:33:23 -0000

    Experts can’t agree how exactly they affect us and it’s not clear that science will give us an answer.

59. Are weight-loss injections the answer to obesity?

    Sun, 19 Mar 2023 00:52:45 -0000

    The appeal is clear - but should we be turning to appetite-suppressing injections?

60. What is assisted dying and how could the law change?

    Wed, 26 Mar 2025 10:17:24 -0000

    MPs backed a proposal to let terminally ill people in England and Wales choose to end their life.

61. Woman 'keeled over in agony' from endometriosis

    Thu, 24 Apr 2025 05:19:28 -0000

    Bekki Thomas is calling for more research into the condition.

62. Premenstrual disorder hits relationships - study

    Thu, 24 Apr 2025 05:10:14 -0000

    PMDD sufferers expressed a lower sense of intimacy, researchers at Durham University say.

63. 'I didn't know I was pregnant until I gave birth'

    Sat, 12 Apr 2025 06:07:21 -0000

    Bryony had no pregnancy symptoms when she went into labour at the beauty salon she worked at.

64. New device gives female patients more dignity

    Sun, 06 Apr 2025 14:17:36 -0000

    A urinary bottle initially designed for men has been adapted to work for women in hospital.

65. Morning-after pill to be made free at pharmacies in England

    Sun, 30 Mar 2025 14:58:18 -0000

    The government hopes the move will end the "unfair postcode lottery" some women face.

66. Wellbeing strategy aims to increase life expectancy

    Sun, 06 Apr 2025 12:20:04 -0000

    A public consultation on the project by Epsom and Ewell Borough Council will run until 16 May.

67. GPs and sports centre join forces

    Wed, 26 Mar 2025 06:01:57 -0000

    A group of GP practices join up with a sports centre operator to open a new healthcare service.

68. Charity's wellness sessions take to the road

    Sun, 09 Mar 2025 13:26:58 -0000

    The iCan organisation's van is offering support to "hard-to-reach" people in parts of Cumbria.

69. Doctors back total ban on smacking children in England

    Thu, 06 Mar 2025 11:15:51 -0000

    Smacking is legal in some cases in England and Northern Ireland, but is banned in Scotland and Wales.

70. Free sauna has become a 'real community hub'

    Wed, 19 Feb 2025 09:56:37 -0000

    The free-to-use sauna in Margate is built in the style of a 19th Century bathing machine.

71. Inside Health

    Tue, 15 Apr 2025 09:00:00 -0000

    James explores the science of a sweet tooth and then gets tips on how to brush like a pro.

72. Inside Health

    Tue, 08 Apr 2025 09:00:00 -0000

    James Gallagher and the panel consider if an assisted death can guarantee a peaceful end.

73. Inside Health

    Tue, 01 Apr 2025 09:00:00 -0000

    James Gallagher and the panel discuss the safeguarding implications of the proposed bill

74. Inside Health

    Tue, 25 Mar 2025 10:00:00 -0000

    In the first of our mini-series we discuss who could get an assisted death under the rules

75. The joy of a visit when you have dementia

    Wed, 30 Apr 2025 08:54:27 -0000

    Visiting a friend or relative with dementia can help reinforce relationships and bring joy.

76. Living well with dementia

    Wed, 30 Apr 2025 08:53:51 -0000

    Why living with dementia can still mean living well.

77. Wrestling for wellbeing... at church

    Tue, 29 Apr 2025 16:09:06 -0000

    Songs of Praise visits a church's wrestling club which helps its members' mental health.

78. 'Dancing is so important for our wellbeing'

    Tue, 29 Apr 2025 16:04:34 -0000

    DJ Annie Mac explains why she set up club nights that don't go on all night.

79. Sitting still for this amount of time is related to high risk of neck pain, study says

    Wed, 30 Apr 2025 16:29:05 -0000

    A new study from China found that longer durations of sedentary behavior can contribute to increased risk of neck pain, particularly with screen usage.

80. Alzheimer’s brain treatment shows promising results in new study

    Wed, 30 Apr 2025 09:00:42 -0000

    Researchers at the University of California, Irvine, have developed a groundbreaking therapy for Alzheimer’s disease by using stem cells to program human immune cells for targeted treatment.

81. Alzheimer's rates have reached staggering number as experts call for change

    Tue, 29 Apr 2025 19:22:14 -0000

    Alzheimer’s early detection is now more accessible with blood tests, as survey data shows nearly 80% of Americans want to know their risk before symptoms appear.

82. Premature death linked to certain type of food, study reveals

    Tue, 29 Apr 2025 15:41:45 -0000

    New research has confirmed that ultraprocessed food consumption is linked to premature death in eight countries, as the U.S. pulls back on synthetic dyes.

83. Paralyzed man with ALS is third to receive NeuraLink implant, can type with brain

    Tue, 29 Apr 2025 09:00:18 -0000

    Brad Smith, an Arizona husband and father with ALS, has become the third person to receive Neuralink, the brain implant made by Elon Musk’s company.

84. ‘Abortion pill’ found to have ‘severe adverse effects’ for 1 in 10 women, study finds

    Mon, 28 Apr 2025 21:55:08 -0000

    A new study reveals "serious adverse events" associated with mifepristone, commonly called the "abortion pill," as researchers and experts highlight potential risks.

85. Alternative cancer treatment could replace chemo and surgery, study suggests

    Mon, 28 Apr 2025 21:14:13 -0000

    A "groundbreaking" cancer treatment trial by Memorial Sloan Kettering shows immunotherapy alone can eliminate some tumors, offering patients an alternative to chemotherapy and surgery.

86. Exercise can prevent cognitive decline even when energy lags, researchers discover

    Mon, 28 Apr 2025 18:55:50 -0000

    Researchers at the University of Missouri discovered that exercise could make up for lost energy, pinpointing a link between liver function and cognitive decline.

87. ‘I’m a pediatrician: I get these top 11 questions about measles’

    Mon, 28 Apr 2025 09:00:29 -0000

    Amid the ongoing measles outbreak, Allison Croucher, a pediatrician in Illinois, said she often gets these questions from parents who are concerned about the spread.

88. ‘SkinnyTok’ weight-loss trend could lead to food deprivation, experts caution

    Sun, 27 Apr 2025 09:00:46 -0000

    The ‘SkinnyTok’ weight-loss trend is raising red flags among health experts, who caution it could encourage food deprivation and harmful behaviors, especially in younger people.

89. RFK Jr. urges Americans to dispose of medicine safely — and to not flush them

    Sat, 26 Apr 2025 16:06:38 -0000

    On National Prescription Drug Take Back Day, HHS Secretary Robert F. Kennedy Jr. is urging Americans to dispose of their prescription medications safely.

90. Woman says dog detected her breast cancer before doctors did: 'He's known this whole time'

    Sat, 26 Apr 2025 12:00:08 -0000

    Diagnosed with an aggressive form of breast cancer at 29, Breanna Bortner found strength and comfort in her dog Mochi, who exhibited signs of awareness and remained by her side during treatment.

91. Exposure to toxin increases colorectal cancer risk among younger adults, study finds

    Fri, 25 Apr 2025 12:36:58 -0000

    Researchers from University of California San Diego have linked a bacterial toxin called colibactin to the increase in early-onset cases of colorectal cancer.

92. 'I’m a spinal surgeon – here’s how your posture is killing your back'

    Fri, 25 Apr 2025 09:00:51 -0000

    Poor posture is likely damaging your back, warns Dr. Arthur Jenkins, a spinal surgeon in New York. He explains how it happens and how to prevent chronic back pain.

93. Woman says ChatGPT saved her life by helping detect cancer, which doctors missed

    Thu, 24 Apr 2025 20:01:15 -0000

    Lauren Bannon, a North Carolina mother, says ChatGPT saved her life by flagging her medical condition after doctors missed it. She shares how the AI chatbot led to her cancer diagnosis.

94. This simple outdoor activity can improve Americans' health, says governor

    Thu, 24 Apr 2025 17:20:48 -0000

    West Virginia has launched a "Mountaineer Mile" in an effort to get Americans outside and moving to increase physical and mental health. The state has been a leader in pushing for MAHA initiatives.

95. Holding paper receipts for just 10 seconds can pose health risks, researchers warn

    Thu, 24 Apr 2025 15:00:40 -0000

    Health researchers caution that Bisphenol S (BPS), an endocrine disruptor present in paper receipts, can rapidly absorb into the skin, leading to a notice of violation against major U.S. retailers.

96. Reality star shares deadly melanoma update as doctors discuss prognosis

    Thu, 24 Apr 2025 09:00:21 -0000

    Doctors discuss the prevalence, risks and treatments of metastatic melanoma, as Teddi Mellencamp reveals the latest updates in her battle with the deadly disease.

97. Vitamin may reduce cancer risk, plus why Joe Rogan quit drinking

    Wed, 23 Apr 2025 22:20:58 -0000

    The Fox News Health Newsletter brings you trending and important stories about health care, drug developments, mental health issues, real people's triumphs over medical struggles, and more.

98. Dancing can help relieve cancer-related side effects, early data shows

    Wed, 23 Apr 2025 22:18:51 -0000

    Preliminary data from The Ohio State University has found that dancing the Argentine tango can help reduce chemotherapy-induced neuropathy symptoms, like burning and tingling.

99. ‘Daunting, frightening': King Charles says about his cancer battle

    Wed, 30 Apr 2025 18:20:15 -0000

    King Charles III has shared his personal experience with cancer He described the diagnosis as "daunting" and "frightening." It’s rare to see royalty express such unfiltered emotion. Yet, right in this moment, King Charles chose to show that beneath the crown is a man who understands pain, courage, and gratitude.

100. 9 toxic cooking oils to avoid in the home kitchen

     Wed, 30 Apr 2025 14:22:12 -0000

     This piece of information talks about such cooking oil that should be avoided and why.

101. Just by drinking 1 glass of water THIS way, one can burn 8 calories

     Wed, 30 Apr 2025 14:00:00 -0000

     Drinking THIS type of water can slightly boost calorie burn as the body works to warm it up, potentially increasing metabolic rate for a short period. While not a miracle weight loss solution, this simple habit can contribute to a healthier routine by adding up to a noticeable calorie deficit over time.

102. Why Meghan sends secret emails to her kids

     Wed, 30 Apr 2025 16:04:48 -0000

     Meghan Markle, five years after stepping down as a senior royal, revealed her unique way of preserving memories for her children, Archie and Lilibet. She creates digital time capsules by emailing them daily snapshots of their lives to private, uniquely named accounts.

103. 5 things to consume if you want crazy hair growth

     Wed, 30 Apr 2025 13:30:00 -0000

     And while chia seeds might be every smoothie bowl’s best friend, this list is diving into some underrated but power-packed foods that can help you grow healthier, longer hair.

104. Kareena Kapoor wears Mizoram’s legacy with a punk twist

     Wed, 30 Apr 2025 13:14:57 -0000

     Mizoram designer Hannah Khiangte blends heritage and high fashion, showcased by Kareena Kapoor Khan at a Bulgari event. Khiangte's label, launched in 2013, empowers Mizo women artisans by transforming traditional 'puan' textiles into contemporary couture. The garment, inspired by the puan's cultural significance, features androgynous tailoring with '80s glam.

105. What happens when you consume a handful of watermelon seeds in summer

     Wed, 30 Apr 2025 10:07:38 -0000

     

106. Cookie: The longest living parrot in history

     Wed, 30 Apr 2025 02:30:00 -0000

     Cookie, a Major Mitchell's cockatoo, arrived at Brookfield Zoo in 1934 and became a symbol of longevity. He was declared the world's oldest living parrot by Guinness World Records in 2015. After retiring in 2009 due to health issues, Cookie passed away at 83, leaving behind a legacy of resilience and the impact of compassionate animal care.

107. 6 foods that are silently damaging the liver

     Tue, 29 Apr 2025 11:55:37 -0000

     Dr Adrian, a Functional Medicine Doctor, often shares tips related to health and wellness on his official Instagram account. As per his post, certain foods are not good for liver health and are discussed below.

108. You just need 2 skills to be successful: Anupam Mittal

     Wed, 30 Apr 2025 12:19:27 -0000

     Shark Tank India's Anupam Mittal advises aspiring entrepreneurs to focus on two key skills, irrespective of their educational background. Mittal emphasizes the importance of 'selling,' which involves convincing people to believe in your vision, and 'building,' which requires focus and perseverance. He believes these 'superpowers' are more crucial than degrees or experience, fostering both entrepreneurial success and personal growth.

109. 5 Chikankari kurtas to steal from B-town celebs

     Wed, 30 Apr 2025 00:30:00 -0000

     Let's take a look at some stunning Chikankari kurtas to steal from Bollywood celebrities.

110. 5 habits of intelligent people to be successful

     Wed, 30 Apr 2025 09:58:00 -0000

     In a world full of noise, deep thinkers stand out. Instead of reacting to challenges or people, these people choose to respond. They reflect, analyse, and choose their actions with intention thus making intelligent and wise choices in life. But what are the habits that makes intelligent people and deepn thinkers stand apart from the rest? Here we list some of them. By understanding and adopting these habits, you can develop a more powerful mindset that will help you be successful, just like them:

111. In pics: Suniel Shetty's beautiful home

     Wed, 30 Apr 2025 11:40:28 -0000

     Suniel Shetty's home is the perfect mix of aesthetics, nature elements, and love. Be it pictures with his dogs, or pictures of the view from the balcony, the home looks oh-so-dreamy and nice, and his balcony garden is every gardener's dream. Here are a few pictures from inside his home.

112. 5 drinks to clear the complexion and get a clear skin

     Wed, 30 Apr 2025 09:39:40 -0000

     Hydration, vitamins, antioxidants, and anti-inflammatory ingredients can do wonders, especially when consumed regularly. So if you’re tired of breakouts, dullness, or uneven tone, maybe it’s time to pay more attention to your drink choices.

113. 'THIS' breakfast is the ultimate secret to long life

     Wed, 30 Apr 2025 08:30:00 -0000

     Okinawans follow the "hara hachi bu" rule, which means they stop eating when they are 80% full. Eating less helps to prevent overeating and maintain a healthy weight. This is something that can be cultivated over a period of time, and eventually your stomach will start rejecting food when it is almost full

114. 8 brain and puzzle games to play to sharpen skills

     Wed, 30 Apr 2025 09:30:00 -0000

     In the era of constant doomscrolling and ‘brainrot’, it is important to engage in activities that keep the brain sharp, active, and alert. And there are certain puzzles and games that help do just that. Here we mention some of them.

115. ​​5 ancient birds that continue to live today​

     Wed, 30 Apr 2025 07:01:07 -0000

     ​Birds have been around for millions of years, evolving from ancient dinosaurs into the wide variety of species we see today. But while many birds have come and gone over millennia, some have remained surprisingly unchanged, surviving through ice ages, escaping predators, and changing landscapes. These feathered creatures are often called living fossils, with origins that go back tens of millions of years, and studying them gives us important information about the distant past and the incredible adaptability of nature.​Today’s birds vary widely in size, habitat, and behaviour, but a few ancient species still glide across our skies just as their ancestors did eons ago. From the deep-diving loons in northern lakes to the powerful, flightless ostriches roaming the African plains, these birds have been around far longer than you’d expect and they’re part of the oldest surviving branches of the bird family tree. Here are five of these ancient bird survivors still living today.​

116. SRK, Priyanka Chopra: 5 Indian celebs at Met Gala 2025

     Wed, 30 Apr 2025 07:11:39 -0000

     The Met Gala is poised to ignite New York on May 5th, potentially showcasing a strong Indian presence. Rumors suggest Shah Rukh Khan, Kiara Advani, Diljit Dosanjh, Priyanka Chopra, and Isha Ambani might grace the red carpet. Anticipation builds for show-stopping looks and viral moments, with possible custom outfits and maternity styles adding to the excitement.

117. Where does gold come from? NASA has the answer

     Wed, 30 Apr 2025 02:56:59 -0000

     As Akshaya Tritiya approaches, a new study suggests the gold in your jewelry and smartphones may originate from magnetar explosions billions of years ago. NASA data indicates that powerful flares from magnetars could account for up to 10% of heavy elements, including gold.

118. Shri Thanedar vs Dinesh D'Souza: How the battle of two Indian-origin Americans shook X

     Wed, 30 Apr 2025 05:07:34 -0000

     A Twitter exchange ignited between Congressman Shri Thanedar and Dinesh D'Souza, sparking debate on immigration, identity, and assimilation. D'Souza's remarks about Thanedar's background drew criticism, prompting responses from Thanedar and his son. The exchange highlights ongoing discussions within the Indian-American community regarding representation and challenges reductive narratives in American society.

119. Experts verify the link between protein intake and increased uric acid levels

     Wed, 30 Apr 2025 13:00:10 -0000

120. India: A Growth Frontier for Sustainable Palm Oil By Dr. Puah Chiew Wei

     Tue, 29 Apr 2025 11:35:42 -0000

121. ‘Can be life-threatening’: Here’s what to do if your blood sugar is 370 mg/dL and higher

     Tue, 29 Apr 2025 07:00:00 -0000

122. ‘I switched it up’: Madhuri Dixit’s husband Dr Shriram Nene reveals he lost 18 kgs and brought body fat down to 16 percent after health scare; here’s what he did

     Mon, 28 Apr 2025 14:00:05 -0000

123. Divyanka Tripathi experiences extreme itching while recovering from dengue; ‘She became a khujli master,’ says husband Vivek Dahiya

     Mon, 28 Apr 2025 07:59:56 -0000

124. ‘I will sip it like a beer because…’: Paresh Rawal admits he drank his urine to heal a knee injury faster; why experts warn against such unproven remedies

     Mon, 28 Apr 2025 06:05:16 -0000

125. Usha Nadkarni, nearing 80, recalls missing out on meals for work despite being a diabetic: ‘Kya bolun main’

     Mon, 28 Apr 2025 04:00:09 -0000

126. What happens to the body when you eat 12 eggs a day?

     Sun, 27 Apr 2025 15:00:47 -0000

127. Add this ingredient in your watermelon drink to make it a weight loss weapon this summer

     Sun, 27 Apr 2025 10:15:38 -0000

128. Tremors, seizures, paralysis: This brain disorder is more common than multiple sclerosis – but often goes undiagnosed

     Sat, 26 Apr 2025 15:00:38 -0000

129. Why you should replace the morning alarm with natural sunlight

     Sat, 26 Apr 2025 10:56:27 -0000

130. Former Miss World contestant Pooja Chopra reveals why she doesn’t like fad diets: ‘Gulab jamun or ras malai, I can eat it all’

     Sat, 26 Apr 2025 08:00:05 -0000

131. Age 36 is when ill-effects of unhealthy habits during young adulthood start to show, study suggests

     Sat, 26 Apr 2025 07:00:02 -0000

132. As Tamil Nadu bans raw-egg mayonnaise, experts explain the health risks of having this condiment

     Sat, 26 Apr 2025 05:01:52 -0000

133. ‘My patients feel I’m gaslighting them’: Harvard-trained doctor tries two methods to decrease anxiety

     Fri, 25 Apr 2025 14:00:06 -0000

134. ‘She had come down to 46-47 kgs’: When Boney Kapoor opened up about Sridevi’s struggles with extreme dieting to look thin on-screen; expert on its harmful effects

     Fri, 25 Apr 2025 07:00:06 -0000

135. Jasmin Bhasin opens up about corneal damage, says ‘shukr karo sab theek hai’; expert shares prevention tips

     Thu, 24 Apr 2025 13:01:40 -0000

136. ‘Rarely have I heard him want to cheat’: Shreyas Iyer’s nutritionist Nicole Linhares Kedia shares cricketer’s IPL meal plan

     Thu, 24 Apr 2025 10:59:08 -0000

137. Man got a fungal infection on his lungs after repeatedly smelling his own socks; doctor explains how

     Thu, 24 Apr 2025 10:00:06 -0000

138. Here’s what happens if you keep mosquito repellent on all night

     Thu, 24 Apr 2025 08:00:01 -0000

139. Nita Ambani reveals why the family chooses to live on the 27th floor of Antilia

     Wed, 23 Apr 2025 16:00:59 -0000

140. This is what happens to the body when you have sugarcane juice every day during the hot and humid months

     Wed, 23 Apr 2025 10:56:51 -0000

141. Turns out, we’ve been blowing our nose wrong all this while; here’s the right way

     Tue, 22 Apr 2025 12:59:18 -0000

142. We asked doctors about viral tips on reducing blood pressure, this is what they said

     Mon, 21 Apr 2025 15:00:52 -0000

143. What it means when food particles show up in your poop

     Mon, 21 Apr 2025 10:57:05 -0000

144. Here’s the incredible story of a pregnant UK cancer patient who gave birth to her baby twice

     Mon, 21 Apr 2025 08:56:59 -0000

145. ‘It’s real!’: New mom Shraddha Arya shares struggles with postpartum hair loss after having twins

     Mon, 21 Apr 2025 06:00:15 -0000

146. Do you clean your tongue daily? This is what happens to your body if you don’t do it for a month

     Mon, 21 Apr 2025 05:00:02 -0000

147. Dietician recommends 10 protein-rich dishes for your diet to meet your daily requirement

     Sun, 20 Apr 2025 14:00:42 -0000

148. Can a pinch of baking soda in drinking water help detox the body?

     Sun, 20 Apr 2025 09:00:10 -0000

149. What does dehydration during pregnancy look like? Signs to watch out for

     Sun, 20 Apr 2025 04:10:37 -0000

150. 5 healthy alternatives to maida you need in your pantry

     Sat, 19 Apr 2025 16:00:20 -0000

151. Fixing food habits can cut liver disease risk by 50 per cent, say experts

     Sat, 19 Apr 2025 14:00:16 -0000

152. Why you must avoid combining two starchy carbohydrate sources in a single meal

     Sat, 19 Apr 2025 11:58:43 -0000

153. After reporting hair loss, Buldhana’s Shegaon residents are suddenly losing nails; We ask experts possible causes

     Sat, 19 Apr 2025 09:00:05 -0000

154. Here’s how much protein you can get for just Rs 100

     Sat, 19 Apr 2025 06:00:17 -0000

155. 6 ways to improve brain functioning

     Fri, 18 Apr 2025 15:00:13 -0000

156. This is what happens to the body if you take paracetamol ‘like it’s Cadbury Gems,’ as a doctor has claimed Indians do

     Fri, 18 Apr 2025 08:57:13 -0000

157. ‘It started with me discovering…’: Karan Johar reveals secret to sudden weight loss and transformation, dismisses Ozempic rumours

     Fri, 18 Apr 2025 08:00:10 -0000

158. From popping painkillers to shortage of sleep, seven common habits that could be harming your kidneys

     Thu, 17 Apr 2025 18:00:49 -0000

159. A cancer survivor lists ‘toxic’ things one should never use at home after being diagnosed at 35 while pregnant; we verify

     Thu, 17 Apr 2025 09:59:11 -0000

160. Are twins allergic to the same things?

     Wed, 16 Apr 2025 15:00:36 -0000

161. Type 5 diabetes: Find out who is more susceptible to this newly discovered condition

     Wed, 16 Apr 2025 10:55:42 -0000

162. This is what happens to the body if you always wear clothes that are too tight

     Wed, 16 Apr 2025 07:00:06 -0000

163. New study finds no evidence technology causes ‘digital dementia’ in older people

     Tue, 15 Apr 2025 15:00:27 -0000

164. Myth or fact: Those who walk fast are at a lower risk of diabetes

     Tue, 15 Apr 2025 10:58:05 -0000

165. ‘She won’t live more than two years’: Madhubala’s sister Madhur Bhushan reflects on the actor’s final years after heart ailment diagnosis; how it can go undetected

     Tue, 15 Apr 2025 06:02:07 -0000

166. Cancer hijacks your brain, steals your motivation — new research in mice reveals how, offering potential avenues for treatment

     Mon, 14 Apr 2025 17:00:20 -0000

167. Why you must never self-medicate

     Mon, 14 Apr 2025 09:00:06 -0000

168. Samantha Ruth Prabhu reveals reason behind not doing junk food ads: ‘Now, I vet my brands with 3 doctors…’

     Mon, 14 Apr 2025 07:58:12 -0000

169. Twin brothers adopt vegan vs meat diet for 6 months; the results might shock you

     Mon, 14 Apr 2025 06:00:06 -0000

170. How often do you daydream? It may be a cause for concern

     Sun, 13 Apr 2025 15:00:29 -0000

171. What happens if droplets of lemon juice are splashed into your eye while squeezing it?

     Sun, 13 Apr 2025 14:00:52 -0000

172. Being married linked to increased risk of dementia: New study

     Sun, 13 Apr 2025 12:30:19 -0000

173. Tired of washing your hair every day? We have a solution for you (literally)

     Sun, 13 Apr 2025 11:30:11 -0000

174. ‘Full fat, full sugar, full maida:’ Celeb nutritionist Rujuta Diwekar advises against skimping on traditional desserts

     Sun, 13 Apr 2025 10:15:53 -0000

175. ‘Diagnosed with lung cancer at stage zero’: Soha Ali Khan on how Sharmila Tagore’s early diagnosis helped; understand what stage zero cancer means

     Sun, 13 Apr 2025 07:59:50 -0000

176. These common foods and beverages may be ruining the health of your skin and hair, according to an expert

     Sun, 13 Apr 2025 04:00:08 -0000

177. Could changing your diet improve endometriosis pain? Recent study suggests it’s possible

     Sat, 12 Apr 2025 15:00:11 -0000

178. Bed rotting vs bed marinating: Which one helps you rest?

     Sat, 12 Apr 2025 14:00:08 -0000

179. What happens to the body when you have bread every day?

     Sat, 12 Apr 2025 11:57:16 -0000

180. Bhagyashree hails gavar phali as ‘Maharashtrian protein’; expert says it is ‘ideal for gut health’

     Sat, 12 Apr 2025 09:56:16 -0000

181. Night-time sleep improves one’s recall of sequence of events, benefits seen even after a year: Study

     Sat, 12 Apr 2025 09:00:08 -0000

182. Reasons your blood sugar level is high despite quitting refined sugar

     Sat, 12 Apr 2025 07:00:12 -0000

183. ‘No surgery. No exercise. No medication:’ A look at R Madhavan’s 21 day weight loss diet plan

     Sat, 12 Apr 2025 04:00:12 -0000

184. ‘She couldn’t catch her breath’: 17-year-old cheerleader diagnosed with ‘popcorn lung’ after years of vaping; experts explain what it is and whether this condition can be treated

     Fri, 11 Apr 2025 12:59:26 -0000

185. ‘Chakku chhuriyan tez kar lo’: Tahira Kashyap, battling breast cancer again, shares song she listened to in operation theatre; expert explains benefits

     Fri, 11 Apr 2025 07:59:47 -0000

186. Should pregnant women drink orange juice before an ultrasound?

     Thu, 10 Apr 2025 15:00:13 -0000

187. Are you overweight or do you have inflammation? Find out with this test

     Thu, 10 Apr 2025 05:00:07 -0000

188. Anjali Anand recalls sleeping only 3 hours a day for five months, says ‘got punished for it’: ‘Just because I am a different size…’

     Wed, 09 Apr 2025 18:00:22 -0000

189. Vitamin D builds your bones and keeps your gut sealed – but many children are deficient

     Wed, 09 Apr 2025 17:00:14 -0000

190. Fermented vs nonfermented milk: Why women should rethink their dairy choices for heart health

     Wed, 09 Apr 2025 13:00:54 -0000

191. Do you feel the need to poop after every meal?

     Wed, 09 Apr 2025 09:00:54 -0000

192. ‘0.6 kg salt, 2 litres oil, and 3 kg sugar’ for family of 4: Andhra Pradesh Chief Minister N Chandrababu Naidu urges people to cut back on intake to reduce disease burden; expert elucidates

     Wed, 09 Apr 2025 06:00:31 -0000

193. Here’s how much toothpaste you should use while brushing

     Tue, 08 Apr 2025 16:00:11 -0000

194. What exactly are ‘blue balls’ and are they dangerous?

     Tue, 08 Apr 2025 14:00:07 -0000

195. ‘It was a lot of fun’: Milind Soman, who ‘used to drink a lot till my late 20s’, opens up about his relationship with alcohol

     Tue, 08 Apr 2025 10:58:31 -0000

196. Find out what happens to the body if you don’t consume enough magnesium

     Tue, 08 Apr 2025 09:55:31 -0000

197. ‘Round 2 for me…’: Ayushmann Khurana calls wife Tahira Kashyap ‘my hero’ after her cancer relapses; doctor explains the reasons

     Mon, 07 Apr 2025 07:59:50 -0000

198. Influencer claims the time of day you shower can affect how much vitamin D your body absorbs; expert weighs in

     Mon, 07 Apr 2025 05:00:13 -0000

199. This fruit can help boost your performance in the bedroom

     Sun, 06 Apr 2025 15:00:22 -0000

200. These changes in your eyes could indicate a trauma response, learn what they are

     Sun, 06 Apr 2025 14:00:10 -0000

201. Add a healthy twist to your daily meals with these 7 varieties of rotis

     Sun, 06 Apr 2025 09:00:30 -0000

202. 6 powerful superfoods that naturally boost gut health

     Sun, 06 Apr 2025 04:00:02 -0000

203. Protein is being added to yoghurt, bread, coffee – but is it really good for our health?

     Sat, 05 Apr 2025 16:00:26 -0000

204. Catwoman actor Halle Berry spills diet and fitness secrets : ‘That’s how I manage my diabetes’

     Sat, 05 Apr 2025 15:00:22 -0000

205. 3 foods to avoid in hot weather; nutritionist shares better alternatives

     Sat, 05 Apr 2025 09:02:05 -0000

206. Increased screen time found to increase depression risk in teen girls by disrupting sleep, study finds

     Sat, 05 Apr 2025 08:00:02 -0000

207. Here’s what happens to the body when you reduce sitting time by 40 minutes per day

     Sat, 05 Apr 2025 05:00:05 -0000

208. Bill Gates supports weight loss drugs, suggests ways to tackle obesity

     Sat, 05 Apr 2025 04:00:12 -0000

209. Men can also experience the symptoms of a pregnancy!

     Fri, 04 Apr 2025 14:00:18 -0000

210. Expert answers: Is passing gas 10-20 times per day normal?

     Fri, 04 Apr 2025 06:00:11 -0000

211. Bengaluru CEO recalls ‘horrific weekend’, says was rushed to ICU after nose bleed: ‘Then came the real shock – my blood pressure was 230’

     Thu, 03 Apr 2025 10:59:25 -0000

212. General, localised, and others: Some symptoms that can signal the presence of cancer much before diagnosis

     Thu, 03 Apr 2025 08:00:33 -0000

213. Top 7 ways to boost your immune system

     Wed, 02 Apr 2025 14:00:07 -0000

214. The three hormones that have a significant influence on physical and emotional well-being are…

     Wed, 02 Apr 2025 08:00:01 -0000

215. Flip-flops or sliders: Which type of footwear should diabetics ideally wear?

     Wed, 02 Apr 2025 06:00:00 -0000

216. Early-onset Alzheimer’s: New drug shows promise in slowing disease

     Tue, 01 Apr 2025 14:00:47 -0000

217. Zerodha’s Nithin Kamath says his body is almost back to normal 14 months after suffering stroke: ‘My writing hasn’t improved at all’

     Tue, 01 Apr 2025 10:59:21 -0000

218. ‘3 quilts, gloves, topi, mota socks’: Hina Khan recalls shivering and feeling extremely cold during chemotherapy

     Tue, 01 Apr 2025 05:00:18 -0000

219. Can tuberculosis be transmitted through kissing or sexual contact?

     Mon, 31 Mar 2025 07:00:07 -0000

220. Chronic kidney disease often goes undiagnosed, but early detection can prevent severe outcomes

     Sun, 30 Mar 2025 16:00:25 -0000

221. Fake dyed kaali dal from Himachal Pradesh sparks health alarms — what happens if you eat it?

     Sun, 30 Mar 2025 08:59:36 -0000

222. Boys with cancer can face infertility as adults. Can storing their stem cells help?

     Sat, 29 Mar 2025 18:00:12 -0000

223. Masaba Gupta enjoys the ‘greatest post-feed protein treat to exist’; here’s why it is essential for breastfeeding moms

     Sat, 29 Mar 2025 10:00:38 -0000

224. This is what will happen to the body if you abruptly stop taking thyroid medication

     Sat, 29 Mar 2025 04:00:03 -0000

225. Kolkata Knight Riders player Ramandeep Singh shares diet plan during peak IPL season: ‘Four egg whites and one whole egg’

     Sat, 29 Mar 2025 03:00:03 -0000

226. Top 10 vitamin supplements for good health

     Fri, 28 Mar 2025 15:30:26 -0000

227. Hina Khan says migraines lasted ‘for days together’ if her scalp got exposed for more than 20-30 minutes: ‘When I had shaved my hair…’

     Fri, 28 Mar 2025 05:00:39 -0000

228. A look at Bryan Johnson’s ‘very affordable’ and ‘dramatically simplified’ morning routine

     Thu, 27 Mar 2025 15:00:00 -0000

229. Insomnia alert: Psychologist recommends changes that can improve sleep

     Thu, 27 Mar 2025 14:00:50 -0000

230. This mineral is required to activate vitamin D in the kidney and liver; find out if you are consuming enough

     Thu, 27 Mar 2025 09:59:34 -0000

231. ‘Nothing is easy’: When Alia Bhatt addressed claims of ‘unnatural’ weight loss after giving birth to Raha; metabolic changes new mothers face

     Thu, 27 Mar 2025 07:00:01 -0000

232. A much-less talked about sign of diabetes is…

     Thu, 27 Mar 2025 06:00:23 -0000

233. If you drive a manual car for over two hours daily, you may be prone to this painful condition

     Wed, 26 Mar 2025 09:00:03 -0000

234. Answered: Why your gas may be smelly and what it indicates

     Wed, 26 Mar 2025 06:58:50 -0000

235. How many hours of uninterrupted sleep should you get every night?

     Tue, 25 Mar 2025 11:57:49 -0000

236. All about leptin resistance and how it affects your body

     Tue, 25 Mar 2025 04:00:06 -0000

237. Brand making stick-on supplements receives 50 lakhs on Shark Tank India; we find out their effectiveness

     Mon, 24 Mar 2025 16:00:18 -0000

238. Here’s what happens to the body if you use too much nasal spray

     Mon, 24 Mar 2025 13:00:55 -0000

239. As UP man performs surgery on himself after watching YouTube videos, expert expresses caution against such practices

     Mon, 24 Mar 2025 07:00:37 -0000

240. Can sleeping with a tape on your mouth really cure ADHD? We asked an expert

     Sun, 23 Mar 2025 15:00:03 -0000

241. What happens to the body when you include one spoon of raw cocoa powder in your diet everyday?

     Sun, 23 Mar 2025 11:56:48 -0000

242. Do you yawn too much? You could be suffering from an iron deficiency

     Sun, 23 Mar 2025 11:00:27 -0000

243. ‘Petha juice is back’: Masaba Gupta includes ash gourd juice in postpartum diet; should new mothers consume it?

     Sun, 23 Mar 2025 08:00:00 -0000

244. Brief guide to vitamin, mineral supplements — when too much of good thing can become toxic

     Sun, 23 Mar 2025 06:59:43 -0000

245. Walnuts vs Almonds: Which nut triggers your acne?

     Sat, 22 Mar 2025 09:57:22 -0000

246. Amateur MMA fighter Jake Sendler dies at 21 from rare muscle condition linked to intense workouts

     Sat, 22 Mar 2025 06:58:47 -0000

247. Ananya Panday swears by this Ayurvedic ‘jeera paani’ morning drink

     Sat, 22 Mar 2025 05:00:09 -0000

248. The ‘MEDSRX’ formula promises to help boost your immunity: ‘Aapko cancer nahi ho sakta’

     Sat, 22 Mar 2025 04:00:17 -0000

249. Weight loss drug Mounjaro launched in India: Know price, how it works, side-effects, and if it’s more effective than Ozempic

     Fri, 21 Mar 2025 08:58:05 -0000

250. Here’s what will happen to the body if you completely stop having protein

     Fri, 21 Mar 2025 05:00:07 -0000

251. This is the best form of exercise for those with type 1 diabetes, study finds

     Thu, 20 Mar 2025 09:59:37 -0000

252. Here’s what may happen if you travel on flight with a cold

     Thu, 20 Mar 2025 08:00:15 -0000

253. Can a daily nap do more harm than good? Sleep researcher explains

     Wed, 19 Mar 2025 15:00:57 -0000

254. How real is gaming disorder, and what should we keep in mind?

     Wed, 19 Mar 2025 07:00:08 -0000

255. Vikram Bhatt on battling autoimmune condition similar to myositis that Samantha Ruth Prabhu suffers from: ‘When big idols like Deepika Padukone…’

     Wed, 19 Mar 2025 06:00:09 -0000

256. ‘Thoda dimaag lagaao’: Hina Khan shares pic of dry, brittle and discoloured nails, says its the ‘most common side-effect of chemotherapy’

     Wed, 19 Mar 2025 04:00:17 -0000

257. Changes to speech and language can help detect Alzheimer’s early — here are five things to look out for

     Tue, 18 Mar 2025 15:00:59 -0000

258. Sports and energy drinks are not the same; here’s how they affect the body, particularly digestive health

     Tue, 18 Mar 2025 09:00:11 -0000

259. My Son Kept Falling When He Was Playing; 24 Hours Later, He Was In A Coma!

     Tue, 18 Mar 2025 04:41:05 -0000

260. Astronauts Sunita Williams and Barry Wilmore spent 9 months in space instead of 1 week — here’s how it may affect their health

     Mon, 17 Mar 2025 07:01:48 -0000

261. Painkillers aren’t one-size-fits-all: Here’s why they may be less effective for women than men

     Mon, 17 Mar 2025 05:00:19 -0000

262. ‘Whole new ball game for heart transplants’: Australian man survives 100 days with artificial titanium heart

     Sun, 16 Mar 2025 11:18:42 -0000

263. Home births are on the rise, but are they safe for women with diabetes?

     Sun, 16 Mar 2025 05:00:42 -0000

264. Samantha swears by Wim Hof breathing technique: Here’s how it can set the tone for your day

     Sat, 15 Mar 2025 15:00:03 -0000

265. What happens to the body if you go on a 3-day mono diet of grapes?

     Sat, 15 Mar 2025 14:00:45 -0000

266. ‘Sleepmaxxing’: All you need to know about the latest trend promising restful sleep

     Sat, 15 Mar 2025 10:00:43 -0000

267. What is the 1-minute gut health test?

     Sat, 15 Mar 2025 05:00:29 -0000

268. Here’s what happens to the body if you do not sleep for 3 days, like Janhvi Kapoor

     Fri, 14 Mar 2025 07:00:11 -0000

269. Warning signs of kidney fungus you shouldn’t ignore (especially if you’re diabetic)

     Thu, 13 Mar 2025 06:00:22 -0000

270. Sana Makbul opens up about battle with autoimmune hepatitis: ‘Samantha Ruth Prabhu has myositis, a muscle condition. I have it with the liver’

     Thu, 13 Mar 2025 04:58:04 -0000

271. Ice baths popular for exercise recovery, general wellness. But what does science say?

     Wed, 12 Mar 2025 17:00:02 -0000

272. Can crossing your legs instantly relieve constipation?

     Wed, 12 Mar 2025 13:00:01 -0000

273. Ekta Kapoor wonders about the best weight loss solution: ‘Ozempic, Mounjaro or anti-inflammatory diet’

     Wed, 12 Mar 2025 11:59:21 -0000

274. Here’s what will happen to the brain if you do not use smartphones for 3 days straight

     Wed, 12 Mar 2025 10:59:32 -0000

275. ‘I was recently clinically diagnosed with ADHD and anxiety’: Alia Bhatt says her body overheats in social situations, here’s why it happens

     Wed, 12 Mar 2025 08:00:10 -0000

276. Why increasing rates of tuberculosis in UK, US should concern everyone

     Tue, 11 Mar 2025 17:00:34 -0000

277. Ginger peel: Find out if you should have it or discard

     Tue, 11 Mar 2025 15:00:41 -0000

278. Bryan Johnson says he ‘started life on the petroleum diet’

     Tue, 11 Mar 2025 14:00:00 -0000

279. How regular bedtime habits are reshaping sleep quality in India

     Tue, 11 Mar 2025 08:59:11 -0000

280. From clear, white, to pink and brown: Know what the colour of your phlegm means

     Tue, 11 Mar 2025 07:00:18 -0000

281. Tanishaa Mukerji shares what happens during egg freezing, why she opted for the medical procedure: ‘You are numb in that area in the stomach’

     Tue, 11 Mar 2025 04:00:10 -0000

282. ‘From that day until now, it’s everyday’: Woman remembers every day of her life in vivid detail

     Mon, 10 Mar 2025 14:00:05 -0000

283. Social media post claims 125-300mg of magnesium per meal can ‘reverse’ depression in just seven days; we ask experts if it is true

     Mon, 10 Mar 2025 07:58:04 -0000

284. Vitamin patches are trending; what are they and how do they work?

     Mon, 10 Mar 2025 03:59:57 -0000

285. Parasitic worms could be hiding in you — how to spot unusual signs

     Sun, 09 Mar 2025 05:59:37 -0000

286. What is lipedema, and why are Indian women more susceptible to it?

     Sun, 09 Mar 2025 05:00:21 -0000

287. Why do diabetics suffer from shoulder pain? This is what an expert has to say

     Sun, 09 Mar 2025 03:56:51 -0000

288. Can melatonin supplements really ‘reverse’ DNA damage caused by lack of sleep?

     Sat, 08 Mar 2025 08:00:02 -0000

289. What is causing the surge in flu cases in Delhi-NCR? Experts explain

     Sat, 08 Mar 2025 06:00:24 -0000

290. Therapeutic laziness: The 2025 sleep trend that embraces doing nothing

     Thu, 06 Mar 2025 16:00:10 -0000

291. Supplements you should avoid taking without consulting an expert

     Thu, 06 Mar 2025 12:00:13 -0000

292. Here’s what happens to the body when you are exposed to EMFs in the environment

     Thu, 06 Mar 2025 08:00:35 -0000

293. What’s the difference between wholemeal and wholegrain bread? Not a whole lot

     Wed, 05 Mar 2025 15:00:37 -0000

294. Here’s how much protein Ivanka Trump consumes per meal: ‘It works… I’ve never been stronger!’

     Wed, 05 Mar 2025 14:00:41 -0000

295. Vitamin B12 strips or tablets: Find out which one you should pick

     Wed, 05 Mar 2025 10:58:32 -0000

296. 10 things a gynaecologist wants you to never do for good vaginal health

     Wed, 05 Mar 2025 09:00:01 -0000

297. This is what happens to the body if you eat an apple a day, like the saying goes

     Wed, 05 Mar 2025 05:00:20 -0000

298. Bryan Johnson injects brain with anti-depressant ketamine: ‘It completely scrambled my…’

     Tue, 04 Mar 2025 14:00:18 -0000

299. Fact check: The brain takes 8 minutes to realise that the stomach is full

     Tue, 04 Mar 2025 09:00:04 -0000

300. This is what happens if you guzzle water after having desserts

     Tue, 04 Mar 2025 07:03:31 -0000

301. Sunaina Roshan reveals how she reversed Grade 3 fatty liver with two simple yet crucial lifestyle changes: ‘Sheer willpower and determination’

     Tue, 04 Mar 2025 06:01:03 -0000

302. Do weight loss drugs like Ozempic directly impact intimacy?

     Tue, 04 Mar 2025 05:00:07 -0000

303. Hina Khan shows radiation burns from cancer treatment, shares a positive note: ‘Scarred not scared’

     Tue, 04 Mar 2025 04:00:30 -0000

304. Intense heat changes our biology, can make us age significantly faster: Study

     Mon, 03 Mar 2025 16:00:54 -0000

305. A neurologist tells us the 3 things they would never do (and why you shouldn’t, too)

     Mon, 03 Mar 2025 14:00:39 -0000

306. Digital creator says ‘age-old remedy’ can help you get rid of spectacles; expert weighs in

     Mon, 03 Mar 2025 09:58:39 -0000

307. Understanding the link between losing muscle mass and diabetes

     Mon, 03 Mar 2025 04:00:04 -0000

308. What happens to the body when you consume excess melatonin?

     Sun, 02 Mar 2025 15:00:03 -0000

309. Lizzo says eating in ‘calorie-deficit and weight training’ her secret to weight loss; expert shares tips on achieving both

     Sun, 02 Mar 2025 13:00:26 -0000

310. Do salads make you feel bloated? Find out why

     Sun, 02 Mar 2025 12:00:56 -0000

311. If you’re on tretinoin, you might not be able to donate blood

     Sun, 02 Mar 2025 07:59:31 -0000

312. Can inserting menstrual cups incorrectly lead to kidney injury? Here’s what you should know

     Sun, 02 Mar 2025 06:00:35 -0000

313. Instead of coffee, these (healthier) drinks can help kids power through the exam season

     Sun, 02 Mar 2025 04:00:39 -0000

314. Eating disorders don’t just affect teen girls. Risk may go up around pregnancy, menopause too

     Sat, 01 Mar 2025 16:00:29 -0000

315. ‘It wasn’t complete torture’: Jacob Elordi on the psychological impact of losing weight as a group activity

     Sat, 01 Mar 2025 15:00:13 -0000

316. Five tips to find what really brings you joy outside of work

     Sat, 01 Mar 2025 09:58:59 -0000

317. Should you drink 2 bottles of water for every cup of coffee? Experts weigh in

     Sat, 01 Mar 2025 06:00:20 -0000

318. What happens to the body if you eat a bowl of guava every day?

     Sat, 01 Mar 2025 04:00:04 -0000

319. Nasal spray shows preclinical promise for treating traumatic brain injury, reveals study

     Wed, 30 Apr 2025 17:00:17 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/08/16/247997-nasal-spray-50.webp' /><p style="text-align: justify; ">A new study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for<a href="https://medicaldialogues.in/topics/traumatic-brain-injury"> traumatic brain injury</a> (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could reduce damage to the central nervous system and behavioral deficits, suggesting a potential therapeutic approach for TBI and other acute forms of <a href="https://medicaldialogues.in/topics/brain-injury">brain injury</a>. The results are published in <i>Nature Neuroscience</i>. </p><p style="text-align: justify; ">“Traumatic brain injury is a leading cause of death and disability-including <a href="https://medicaldialogues.in/topics/cognitive-decline">cognitive decline</a>-and chronic inflammation is one of the key reasons,” said lead author Saef Izzy, MD, FNCS, FAAN, a neurologist and head of the Immunology of Brain Injury Program at Brigham and Women’s Hospital (BWH), a founding member of the Mass General Brigham healthcare system. “Currently, there is no treatment to prevent the long-term effects of traumatic brain injury.” </p><p style="text-align: justify;">The study examines the monoclonal antibody Foralumab, made by Tiziana, which has been tested in clinical trials for patients with <a href="https://medicaldialogues.in/topics/multiple-sclerosis">multiple sclerosis</a>, <a href="https://medicaldialogues.in/topics/alzheimer%E2%80%99s-disease">Alzheimer’s disease</a>, and other conditions. </p><p style="text-align: justify;">“This opens up a whole new area of research and treatment in traumatic brain injury, something that’s almost impossible to treat,” said senior author Howard Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at BWH. “It also means this could work in intracerebral hemorrhage and other stroke patients with brain injury.” </p><p style="text-align: justify;">Multiple experiments were done in mouse models with moderate-to-severe traumatic brain injury to explore the communication between regulatory cells induced by the nasal treatment and the microglial immune cells in the brain. Over time, researchers were able to identify how they modulate immune response. </p><p style="text-align: justify;">“Modulating the neuroinflammatory response correlated with improved neurological outcomes, including less anxiety, cognitive decline, and improved motor skills,” Izzy said. </p><p style="text-align: justify;">In addition to assessing the effects of the treatment, the research team was able to learn about immune response over time and compare the immune responses and effects of TBI in the mice. </p><p style="text-align: justify;">The next step in the research is to translate the findings from preclinical models to human patients. </p><p style="text-align: justify;">“Our patients with traumatic brain injury still don’t have an effective therapeutic to improve their outcomes, so this is a very promising and exciting time to move forward with something that’s backed up with solid science and get it to patients’ bedsides,” said Izzy. </p><p style="text-align: justify;">Once in the clinical setting, Weiner said the hope is this treatment could be used on a variety of traumatic brain injury patients, including football players with repetitive concussions. </p><p style="text-align: justify; ">“We envision giving a nasal spray right there on the sidelines,” said Weiner. “It isn’t something we can do yet, but we see the potential.”</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Izzy, S., Yahya, T., Albastaki, O. et al. Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg–microglia crosstalk. Nat Neurosci (2025). https://doi.org/10.1038/s41593-025-01877-7</p>

320. Obesity and Hypothyroxinemia Together Heighten Risk of LGA Births in Pregnant Women: Study Finds

     Wed, 30 Apr 2025 15:45:12 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/07/30/245485-maternal-obesity.webp' /><p style="text-align: justify; ">China: A recent Chinese cohort study published in<em> Reproductive Biology and Endocrinology </em>has found that <a href="https://speciality.medicaldialogues.in/topics/maternal-obesity">maternal obesity</a> and isolated maternal hypothyroxinemia (IMH) in late pregnancy significantly increase the risk of <a href="https://medicaldialogues.in/topics/large-for-gestational-age">large-for-gestational-age (LGA) </a>births. IMH, defined by low free thyroxine (FT4) with normal thyroid-stimulating hormone (TSH) levels, independently raised LGA risk by 1.3 times.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Obesity alone was linked to a nearly sixfold higher LGA risk and a sevenfold increase in IMH. Notably, women with both conditions had a 7.6-fold greater risk of delivering LGA newborns, indicating a strong synergistic effect. The findings highlight the importance of monitoring <a href="https://medicaldialogues.in/topics/body-mass-index">BMI </a>and thyroid function during pregnancy.</p><p style="text-align: justify; ">The combined impact of isolated maternal hypothyroxinemia and other contributing factors on fetal growth outcomes has not been well established. To address this gap, Bin Zhang, Nanjing Medical University, Changzhou, China, and colleagues aimed to investigate whether the presence of IMH in the third trimester—characterized by free thyroxine (FT4) levels below the 5th percentile and TSH levels within the normal range—along with elevated prenatal body mass index (BMI), jointly increases the risk of delivering large-for-gestational-age newborns. </p><p style="text-align: justify; ">For this purpose, the researchers conducted a retrospective analysis of 11,478 Chinese pregnant women, utilizing laboratory data, including thyroid hormone levels, routine biochemical tests, and hospitalization records from a specialized hospital. </p><p style="text-align: justify; ">The study led to the following findings:</p><ul><li style="text-align: justify; ">The prevalence of obesity (BMI ≥ 30 kg/m²) and isolated maternal hypothyroxinemia (IMH) among the study population was 20.1% and 4.5%, respectively.</li><li style="text-align: justify; ">Obese women had a 6.96-fold higher risk of developing IMH compared to women with normal weight (BMI &lt; 25 kg/m²).</li><li style="text-align: justify; ">The risk of delivering large-for-gestational-age (LGA) newborns was 5.88 times higher in obese women than in those with normal weight.</li><li style="text-align: justify; ">Women with IMH had a 1.32-fold increased risk of LGA births compared to euthyroid women.</li><li style="text-align: justify; ">These associations remained consistent in sensitivity analyses conducted among women under 35, first-time mothers, and those without pregnancy complications.</li><li style="text-align: justify; ">Women with both obesity and IMH had a 7.60-fold greater risk of delivering LGA newborns compared to euthyroid women with normal weight.</li><li style="text-align: justify; ">There was a statistically significant interaction between BMI categories and IMH on the risk of LGA births.</li><li style="text-align: justify; ">Subgroup analyses confirmed this interaction among younger women, those with multiple pregnancies, and those without pregnancy-related complications.</li></ul><p style="text-align: justify; ">The researchers found that in the large cohort of Chinese pregnant women, both obesity and isolated maternal hypothyroxinemia (IMH) in late pregnancy were independently associated with an increased risk of delivering large-for-gestational-age newborns. Notably, the coexistence of these two conditions further amplified this risk.</p><p style="text-align: justify; ">"The findings emphasize the potential value of combining prenatal BMI assessment with thyroid hormone profiling to identify women at elevated risk for LGA births," the authors stated. They further noted, "If confirmed in future studies, this approach could have significant clinical and public health implications, particularly given the growing concern surrounding LGA-related health outcomes."</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Zhang, B., Xi, S., Zhan, Z. et al. Maternal obesity and the incidence of large-for-gestational-age newborns in isolated hypothyroxinemia pregnancies: a comparative cohort study. Reprod Biol Endocrinol 23, 60 (2025). https://doi.org/10.1186/s12958-025-01394-z</p></div><p style="text-align: justify; "><br></p>

321. Early-life exposure to air and light pollution linked to increased risk of pediatric thyroid cancer: Study

     Wed, 30 Apr 2025 15:30:24 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/18/283495-thyroid-cancer.webp' /><p style="text-align: justify; ">&nbsp;A new study led by researchers at Yale University suggests that early-life exposure to two widespread environmental pollutants-small particle <a href="https://medicaldialogues.in/topics/air-pollution">air pollution</a> and outdoor artificial light at night-could increase the risk of pediatric <a href="https://medicaldialogues.in/topics/thyroid-cancer">thyroid cancer</a>. </p><p style="text-align: justify;">The study-a collaborative effort involving multiple Yale departments and institutions across the U.S.-found a “significant association” between exposure to ambient fine particulate matter air pollution (PM2.5) and outdoor artificial light at night (O-ALAN) and increased risk of papillary thyroid <a href="https://medicaldialogues.in/topics/cancer">cancer</a> in children and young adults up to 19 years old. The exposures occurred during the perinatal stage of life, typically defined as the time from when pregnancy occurs up to a year after birth. </p><p style="text-align: justify;">“These results are concerning, especially given how widespread both of these exposures are,” said Dr. Nicole Deziel, PhD, MHS, an environmental epidemiologist with the Yale School of Public Health (YSPH) and the study’s lead author. “Fine particulate matter is found in urban air pollution due to automobile traffic and industrial activity, and artificial light at night is common, particularly in densely populated urban areas.” </p><p style="text-align: justify;">The research team analyzed data from 736 individuals diagnosed with papillary thyroid cancer before age 20 and 36,800 matched control participants based on birth year. Using advanced geospatial and satellite modeling, the team assessed individual-level exposure to PM2.5 and O-ALAN based on residential location at birth. All of the study participants were from California. </p><p style="text-align: justify;">The findings showed that for every 10 micrograms per cubic meter increase in PM2.5 exposure, the odds of developing thyroid cancer rose by 7% overall. The strongest association between exposure and thyroid cancer was found among teenagers (15–19 years of age) and Hispanic children. Similarly, children born in areas with high levels of exposure to outdoor light at night were 23–25% more likely to develop thyroid cancer, according to the study. </p><p style="text-align: justify;">"Thyroid cancer is among the fastest growing cancers among children and adolescents, yet we know very little about what causes it in this population," said Deziel, an associate professor of epidemiology (environmental health sciences) and co-director of the Yale Center for Perinatal, Pediatric, and Environmental Epidemiology. "Our study is the first large-scale investigation to suggest that these exposures early in life-specifically to PM2.5 and outdoor light at night-may play a role in this concerning trend." </p><p style="text-align: justify;">In addition to Deziel, the research team included experts from Yale’s Departments of Biostatistics, Chronic Disease Epidemiology, and Pediatrics, as well as researchers from the University of Southern California, UC Berkeley, and the American Cancer Society. Deziel and several of the study’s authors are affiliated with the Yale Cancer Center. The team’s collective expertise ranged from environmental exposure modeling and biostatistics to pediatric endocrinology and cancer epidemiology. </p><p style="text-align: justify;">The impact of papillary thyroid cancer on children can be extensive. </p><p style="text-align: justify;">Compared to adults, children are often diagnosed with thyroid cancer at more advanced stages with larger tumor sizes. Pediatric survivors of thyroid cancer can suffer aftereffects ranging from temperature dysregulation and headaches to physical disabilities and mental fatigue. The disease can interfere with important life milestones such as education, employment, and raising a family and it can contribute to feelings of anxiety and depression. </p><p style="text-align: justify;">Both PM2.5 and O-ALAN are considered environmental carcinogens that have been shown to disrupt the body’s endocrine system, including thyroid function, in animals and adults. The particles associated with PM2.5 pose a threat because they are small enough to enter the bloodstream and can interfere with hormone signaling, including those involved in regulating cancer pathways. Outdoor artificial light at night has been shown to suppress melatonin and alter circadian rhythms, which can also influence hormone-regulated cancer pathways. </p><p style="text-align: justify; ">The current research raises important environmental justice concerns. Communities of color and lower-income populations are often disproportionately exposed to both air pollution and light pollution-inequities that may contribute to the higher thyroid cancer burden observed in Hispanic children. </p><p style="text-align: justify;">The researchers emphasized that more work is needed to replicate and expand on their findings, ideally using improved exposure metrics and longitudinal designs. </p><p style="text-align: justify;">“In the meantime,” Deziel noted, “our results point to the critical importance of addressing environmental factors in childhood cancer research. Reducing exposures to air pollution and managing light pollution could be important steps in protecting children's health.”</p><p style="text-align: justify;">Reference:</p><p style="text-align: justify;">&nbsp;Nicole C. Deziel, Rong Wang, Joshua L. Warren, Catherine Dinauer, Perinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer, Environmental Health Perspectives, https://doi.org/10.1289/EHP14849.</p>

322. Menopause Age Key to Unlocking Type 2 Diabetes Risk, suggests study

     Wed, 30 Apr 2025 15:30:14 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/23/232860-menopause-50.webp' /><p align="justify">Recent research indicates a potential association between age at menopause and the incidence of type 2 diabetes (T2D), yet comprehensive evidence remains limited, especially among Asian populations. A cohort study involving over 1.1 million postmenopausal Korean women aimed to clarify whether age at menopause and instances of premature menopause are linked to the onset of T2D.</p><p align="justify">Significance of Type 2 Diabetes</p><p align="justify">Type 2 diabetes represents a chronic health issue significantly contributing to cardiovascular diseases, microvascular complications, and elevated mortality rates. Despite advances in medical treatments, T2D prevalence continues to rise, emphasizing the need for effective preventative measures and the identification of at-risk populations. While men are generally at a higher risk at younger ages, the risk for women escalates post-menopause. Female-specific risk factors and their implications on health, particularly links to cardiovascular disease and T2D, are under-explored.</p><p align="justify">Data Collection Methodology</p><p align="justify">The study utilized data from the Korean National Health Insurance Service, which covers nearly the entire South Korean population, providing robust health examination records including self-reported data and clinical health assessments. A total of 3,181,150 women aged 30 and above were initially screened, with exclusions for pre-existing T2D, premenopausal status, and data inconsistencies, resulting in a final cohort of 1,125,378 participants. Age at menopause was self-reported, categorized into four groups: &lt;40 years, 40-44 years, 45-49 years, and ≥50 years, with premature menopause defined as menopause before age 40. Identified T2D cases were defined as fasting blood glucose levels of 126 mg/dL or higher or records of antidiabetic medication claims.</p><p align="justify">Follow-Up Results</p><p align="justify">Throughout a median follow-up of 8.4 years, 113,864 new T2D cases emerged, indicating a cumulative incidence of approximately 10.1%. The results indicated that women with premature menopause had a higher incidence of T2D compared to their peers, with a hazard ratio (HR) of 1.13 after accounting for various confounders. Women experiencing menopause at an earlier age (particularly &lt;40 years) faced a significantly increased risk for developing T2D, corresponding with the hypothesis that lower estrogen levels, due to shorter exposure periods, may contribute significantly to insulin resistance and metabolic dysregulation.</p><p align="justify">Subgroup Analysis Insights</p><p align="justify">Subgroup analyses revealed nuances in the relationship, with factors like body mass index (BMI) and depressive disorders influencing the risk association. Notably, the risk was exacerbated among individuals without obesity and those struggling with depressive disorders, suggesting a potential interaction between mental health and metabolic outcomes.</p><p align="justify">Implications of Findings</p><p align="justify">The findings support the hypothesis that both premature and early menopause can act as significant risk factors for the development of T2D. Given these associations, there is a strong argument for including menopause history in T2D screening protocols. Recommendations suggest recognizing premature menopause as a noteworthy risk factor within diabetes management guidelines, emphasizing preventive care strategies and early detection initiatives.</p><p align="justify">Conclusions and Future Directions</p><p align="justify">Overall, the study elucidates important links between menopausal age and T2D incidence, advocating for greater awareness and proactive measures in managing women’s health, particularly concerning metabolic disorders in postmenopausal populations. Further research is essential to explore these relationships across diverse demographic groups and establish effective interventions to mitigate T2D risk.</p><p align="justify">Key Points</p><p align="justify">- A cohort study involving over 1.1 million postmenopausal Korean women was conducted to investigate the association between age at menopause, instances of premature menopause, and the incidence of type 2 diabetes (T2D), particularly as evidence is lacking in Asian populations. </p><p align="justify">- Type 2 diabetes is a chronic health concern linked to cardiovascular diseases and increased mortality rates, with rising prevalence emphasizing the necessity for effective preventive strategies. The risk for women increases significantly post-menopause, making female-specific health factors critical for understanding T2D risk. </p><p align="justify">- The study analyzed comprehensive health data from the Korean National Health Insurance Service, screening 3,181,150 women aged 30 and above and narrowing the final cohort to 1,125,378. Age at menopause was categorized, and T2D was defined through specific blood glucose levels and medication records. </p><p align="justify">- Over a median follow-up of 8.4 years, 113,864 new T2D cases emerged, indicating a cumulative incidence of approximately 10.1%. Women experiencing premature menopause exhibited a higher incidence of T2D (hazard ratio of 1.13), particularly those with menopause before age 40, indicating potential metabolic dysregulation linked to lower estrogen levels. </p><p align="justify">- Subgroup analyses indicated that body mass index (BMI) and depressive disorders significantly influenced the risk association. Increased T2D risk was noted in individuals without obesity and those with depressive issues, suggesting a complex interplay between mental health and metabolic conditions. </p><p align="justify">- The study underscores the necessity of incorporating menopause history into T2D screening protocols, advocating for recognizing premature menopause as a critical risk factor in diabetes management. Recommendations emphasize the importance of preventive strategies and early detection among postmenopausal women to mitigate T2D risk.</p><p align="justify">Reference –</p><p align="justify">B. Ko et al. (2025). Age At Menopause And Development Of Type 2 Diabetes In Korea. *JAMA Network Open*, 8. https://doi.org/10.1001/jamanetworkopen.2024.55388.</p><p align="justify"><br></p><p align="justify"><br></p><p align="justify"><br></p>

323. Weekly Home BP Monitoring Enhances Hypertension Detection in Hemodialysis Patients: Study Finds

     Wed, 30 Apr 2025 15:30:08 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/19/232503-hemodialysis-50.webp' /><p style="text-align: justify; ">Greece: Accurate blood pressure (BP) monitoring is essential for managing <a href="https://medicaldialogues.in/topics/hypertension">hypertension </a>in patients undergoing <a href="https://medicaldialogues.in/topics/hemodialysis">hemodialysis</a>. A recent study found that in hemodialysis patients, home blood pressure monitoring (HBPM) over a week was more accurate in detecting hypertension than routine BP measurements taken at dialysis centers.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">"HBPM demonstrated greater diagnostic accuracy than 44-hour ambulatory BP monitoring (AUC: 0.934). With a threshold of 141.0 mmHg, HBPM achieved optimal sensitivity (85.7%) and specificity (92.9%), reinforcing its value as a reliable screening tool for this patient population," the researchers reported in the<em> Journal of Human Hypertension. </em></p><p style="text-align: justify; ">The best approach for diagnosing hypertension in hemodialysis patients remains a subject of debate. To address this, Panagiotis I. Georgianos, 2nd Department of Nephrology, AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, and colleagues evaluated the accuracy of home blood pressure monitoring and routine dialysis-unit BP recordings, using 44-hour <a href="https://medicaldialogues.in/topics/ambulatory-blood-pressure-monitoring">ambulatory BP monitoring</a> (ABPM) as the reference standard. </p><p style="text-align: justify; ">For this purpose, the researchers assessed hypertension over two weeks using three methods: (i) routine predialysis and post dialysis BP recordings averaged over six consecutive dialysis sessions, (ii) home BP monitoring (HBPM) for seven days with duplicate morning and evening measurements (Microlife WatchBP Home N), and (iii) 44-hour ambulatory BP monitoring (ABPM) with 20-minute intervals over an entire interdialytic period (Microlife WatchBPO3). The study included 70 patients (mean age: 65.3 ± 13.2 years), 87.1% receiving hypertension treatment, and an average 44-hour ambulatory systolic/diastolic BP of 120.6 ± 15.2/66.3 ± 10.1 mmHg. </p><p style="text-align: justify; ">Based on the study, the researchers reported the following findings:</p><ul><li><div style="text-align: justify;">The mean difference between ambulatory daytime systolic BP (SBP) and routine BP measurements was:</div><ul><li style="text-align: justify; ">Predialysis SBP: -11.4 ± 13.4 mmHg</li><li style="text-align: justify; ">Postdialysis SBP: -4.0 ± 15.1 mmHg</li><li style="text-align: justify; ">Home SBP: -8.6 ± 10.7 mmHg</li></ul></li><li><div style="text-align: justify;">Home BP monitoring (HBPM) showed superior diagnostic performance for detecting ambulatory daytime SBP ≥135 mmHg:</div><ul><li style="text-align: justify; ">Home SBP: AUC 0.934</li><li style="text-align: justify; ">Predialysis SBP: AUC 0.778</li><li style="text-align: justify; ">Postdialysis SBP: AUC 0.766</li><li style="text-align: justify; ">HBPM was significantly more accurate than both predialysis and postdialysis SBP (P = 0.02).</li></ul></li><li style="text-align: justify; ">At a cut-off of 141.0 mmHg, home SBP provided the best balance of sensitivity (85.7%) and specificity (92.9%) for diagnosing hypertension.</li></ul><p style="text-align: justify; ">The study findings highlight that in hemodialysis patients, home blood pressure monitoring conducted over a week is more reliable than routine dialysis-unit BP recordings averaged over two weeks in detecting ambulatory hypertension. HBPM demonstrated greater accuracy in identifying elevated blood pressure levels, making it a valuable tool for improving hypertension diagnosis in this population.</p><p style="text-align: justify; ">"These results suggest that integrating HBPM into routine clinical practice could enhance blood pressure management, leading to better cardiovascular outcomes for hemodialysis patients," the authors concluded. </p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Leonidou, K., Georgianos, P. I., Kollias, A., Kontogiorgos, I., Vaios, V., Leivaditis, K., Karligkiotis, A., Stamellou, E., Balaskas, E. V., Stergiou, G. S., &amp; Liakopoulos, V. (2025). Home versus routine dialysis-unit blood pressure recordings among patients on hemodialysis. Journal of Human Hypertension, 1-7. https://doi.org/10.1038/s41371-025-01007-7</p></div><p style="text-align: justify; "><br></p>

324. Statins Reduce Liver Cancer and Hepatic Decompensation Risk among patients with chronic liver disease: JAMA

     Wed, 30 Apr 2025 15:15:32 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/18/278953-114687.webp' /><p>Researchers have found in a new cohort study that the use of statins in patients with chronic liver disease was associated with a lower risk of liver cancer and hepatic decompensation. Patients who used statins experienced a significant reduction in these risks compared to those who did not, with lipophilic statins and longer treatment duration providing even greater protective effects. Statins may help prevent hepatocellular carcinoma by slowing the progression of liver fibrosis, which is a key factor in the severity of liver disease. This study examined the relationship between the use of statins and the risk of hepatocellular carcinoma and hepatic decompensation, with a focus on how statins influence the progression of liver fibrosis. Researchers analyzed patient data from the year 2000 to the year 2023, selecting adults who were 40 years or older with chronic liver disease and an elevated baseline Fibrosis-4 score, which is a measure of liver fibrosis. Participants were categorized into those who used statins and those who did not, and their health outcomes were tracked over a ten-year period. Findings indicated that patients who used statins had a significantly lower incidence of hepatocellular carcinoma and hepatic decompensation than those who did not use statins. The protective effects were particularly pronounced among individuals who used lipophilic statins and those who had prolonged statin therapy. In addition to reducing the risks of liver cancer and hepatic decompensation, patients who used statins showed a slower progression of liver fibrosis and were more likely to improve their fibrosis risk category over time. Among patients with intermediate or high Fibrosis-4 scores at baseline, those who used statins were more likely to experience a regression in their fibrosis severity compared to those who did not use statins. This suggests that statins may not only help prevent severe liver complications but also contribute to improved liver health over time. Overall, the study supports the potential role of statins in reducing the risk of hepatocellular carcinoma and slowing the progression of liver disease. These findings highlight the need for further research on incorporating statins into treatment strategies for patients with chronic liver disease.</p><p><span style="text-align: justify;">Reference:</span></p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">Choi J, Nguyen VH, Przybyszewski E, et al. Statin Use and Risk of Hepatocellular Carcinoma and Liver Fibrosis in Chronic Liver Disease. JAMA Intern Med. Published online March 17, 2025. doi:10.1001/jamainternmed.2025.0115</p><div style="text-align: justify;"><br></div><p dir="ltr" style="text-align: justify; ">Keywords:</p><p dir="ltr" style="text-align: justify; ">Statins, Reduce, Liver Cancer, Hepatic, Decompensation Risk, among, patients, chronic liver disease, JAMA, Choi J, Nguyen VH, Przybyszewski E, JAMA Intern Med</p><div style="text-align: justify;"><br></div><div style="text-align: justify;"><br></div></div><p style="text-align: justify; "><br></p>

325. Long-Term Use of Inhaled Corticosteroids Linked to Increased diabetes, Health Risks in COPD Patients: Study

     Wed, 30 Apr 2025 15:15:26 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/13/282912-750x450226058-diabetes-2.webp' /><p style="text-align: justify; ">According to a study published in the Annals of Family Medicinereports that using inhaled corticosteroids for more than 24 months significantly increases the risks of diabetes, pneumonia, osteoporosis, cataracts, and fractures in adults with chronic obstructive pulmonary disease (COPD), compared to those who use them for shorter periods. Researchers also observed that these medications are frequently prescribed beyond the recommended guidelines for COPD management.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">They aimed to assess long-term inhaled corticosteroid (ICS) risks in chronic obstructive pulmonary disease (COPD) management. They extracted electronic health record data for individuals aged &gt;45 years with COPD from a data repository. The prevalent cohort required a diagnosis of COPD any time during the observation period, and the inception cohort required a diagnosis of COPD made after entry into the database. A composite outcome of any new diagnosis of type 2 diabetes, cataracts, pneumonia, osteoporosis, or nontraumatic fracture; and recurrent event outcomes of repeated pneumonia or nontraumatic fracture were compared for long-term (&gt;24 months) vs short-term (&lt;4 months) ICS exposure. They assessed outcomes for 318,385 and 209,062 individuals in the prevalent and inception cohorts, respectively. The composite dichotomous outcome was significantly greater for long-term vs short-term ICS use for the prevalent (hazard ratio [HR] = 2.65; 95% CI, 2.62-2.68; P &lt;.001) and inception (HR = 2.60; 95% CI, 2.56-2.64; P &lt;.001) cohorts. For the inception cohort, the absolute risk difference of the composite outcome was 20.26% (29.41% minus 9.15%), with a number needed to harm of 5. Hazard ratios were significantly increased in the prevalent and inception cohorts for recurrent pneumonia (HR = 2.88; 95% CI, 2.62-3.16; P &lt;.001 and HR = 2.85; 95% CI, 2.53-3.22; P &lt;.001, respectively) and recurrent fracture (HR = 1.77; 95% CI, 1.42-2.21; P &lt;.001 and HR = 1.57; 95% CI, 1.20-2.06; P &lt;.001). Long-term ICS use for COPD is associated with significantly greater rates of the composite outcome of type 2 diabetes, cataracts, pneumonia, osteoporosis, and nontraumatic fracture; recurrent pneumonia; and recurrent fracture.</p><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Adverse Outcomes Associated With Inhaled Corticosteroid Use in Individuals With Chronic Obstructive Pulmonary Disease</p><p dir="ltr" style="text-align: justify; ">Wilson D. Pace, Elisabeth Callen, Gabriela Gaona-Villarreal, Asif Shaikh, Barbara P. Yawn</p><p dir="ltr" style="text-align: justify; ">The Annals of Family Medicine Mar 2025, 23 (2) 127-135; DOI: 10.1370/afm.240030</p><p dir="ltr" style="text-align: justify; ">Keywords:</p><p dir="ltr" style="text-align: justify; ">Long-Term, Use, Inhaled, Corticosteroids, Linked, Increased, diabetes, Health, Risks, COPD Patient, Study, Wilson D. Pace, Elisabeth Callen, Gabriela Gaona-Villarreal, Asif Shaikh, Barbara </p><div style="text-align: justify;"><br></div></div><p style="text-align: justify; "><br></p>

326. Ropivacaine safe and effective alternative to lidocaine for local anesthesia in orthognathic procedures: Study

     Wed, 30 Apr 2025 15:15:11 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/18/278954-9-15.webp' /><p style="text-align: justify; ">Ropivacaine safe and effective alternative to lidocaine for local anaesthesia in orthognathic procedures suggests a new study published in the Inflammopharmacology.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">This triple-blind, controlled clinical trial aimed to assess the effects of ropivacaine and lidocaine on hemodynamic factors, blood loss, opioid consumption, and postoperative pain in patients undergoing orthognathic surgery. Thirty-two patients with Class III malocclusion scheduled for orthognathic surgery were included. The participants were randomly assigned to receive 0.5% ropivacaine or 2% lidocaine with 1:80,000 epinephrine for local anesthesia (n = 16). Hemodynamic parameters were recorded at various time intervals, which included heart rate (HR), systolic blood pressure, diastolic blood pressure, mean arterial pressure, oxygen saturation (SpO2), intraoperative bleeding, opioid consumption, and postoperative pain intensity.RESULTS: The participants' mean age was 23.67 ± 4.56 years, and 75% were female. The groups were comparable in most measured outcomes. HR was significantly higher in the ropivacaine group at 30 and 60 min post-injection (P &lt; 0.05). SpO2 percentages were comparable between the groups, except at 15 min post-anesthesia, where the lidocaine group demonstrated a significantly higher SpO2 (P = 0.029). Blood pressure, postoperative opioid consumption, intraoperative bleeding, and postoperative pain levels showed no statistically significant differences between the two groups. Within the limitations of this study, both 0.5% ropivacaine and lidocaine with epinephrine demonstrated comparable effects on hemodynamic stability, intraoperative blood loss, postoperative pain levels, and opioid consumption in patients undergoing orthognathic surgery. These findings suggest that ropivacaine may serve as a safe and effective alternative to lidocaine for local anesthesia in orthognathic procedures.</p><div style="text-align: justify;"><br></div><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Hosseini-Abrishami, Majid, et al. "Ropivacaine Effect On Hemostasis and Pain Level in Patients Undergoing Orthognathic Surgery: a Triple-blinded, Randomized, Clinical Trial." Inflammopharmacology, 2025.</p><p dir="ltr" style="text-align: justify; ">Keywords:</p><p dir="ltr" style="text-align: justify; ">Ropivacaine, safe, effective, alternative, lidocaine, local anesthesia, orthognathic procedures, Study, Hosseini-Abrishami, Maji </p><div style="text-align: justify;"><br></div><div style="text-align: justify;"><br></div><div style="text-align: justify;"><br></div></div><p style="text-align: justify; "><br></p>

327. Elevated TyG-BMI Linked to Higher Short-Term Mortality in Critically Ill Ischemic Stroke Patients: Study Finds

     Wed, 30 Apr 2025 15:15:02 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/05/20/238700-critically-ill.webp' /><p style="text-align: justify; ">China: A recent study published in<em> Cardiovascular Diabetology </em>has highlighted a significant association between elevated<a href="https://medicaldialogues.in/topics/TyG-BMI"> triglyceride glucose-body mass index (TyG-BMI)</a> and an increased risk of short-term <a href="https://medicaldialogues.in/topics/deaths">mortality </a>in critically ill patients with <a href="https://medicaldialogues.in/topics/ischemic-stroke">ischemic stroke (IS)</a>. The findings suggest that TyG-BMI could serve as a simple yet effective biomarker for identifying high-risk patients, aiding in early intervention and improved clinical outcomes.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Ischemic stroke, a leading cause of disability and death worldwide, requires timely risk assessment to enhance patient management in critical care settings. The triglyceride glucose-body mass index is a widely recognized marker for evaluating insulin resistance (IR) and has been strongly linked to stroke. However, the researchers note that research in this area remains limited, and existing studies have reported inconsistent findings.</p><p style="text-align: justify; ">To fill this knowledge gap, Ming Yu, Department of Neurology, Suining Central Hospital, Suining, China, and colleagues aimed to explore the association between TyG-BMI and 28-day mortality in critically ill ischemic stroke patients using data from the eICU database. This study seeks to bridge existing research gaps and provide more precise biomarker references for clinical use. </p><p style="text-align: justify; ">For this purpose, the researchers used multivariate Cox regression models to assess the impact of TyG-BMI on 28-day hospital and ICU mortality. Restricted cubic splines (RCS) were applied to examine potential nonlinear relationships, while Kaplan-Meier (K-M) curves were used to compare outcomes across different TyG-BMI groups. Subgroup analyses were also conducted to ensure result reliability and interaction. </p><p style="text-align: justify; "><strong>The following were the key findings:</strong></p><ul><li style="text-align: justify; ">The study included 1,362 critically ill ischemic stroke patients with a mean age of 68.41 ± 14.16 years, of whom 47.50% were male.</li><li style="text-align: justify; ">Multivariate Cox regression analysis showed that patients in the high TyG-BMI group had significantly higher 28-day hospital mortality (HR = 1.734) and ICU mortality (HR = 2.337).</li><li style="text-align: justify; ">Restricted cubic spline (RCS) analysis revealed a nonlinear positive correlation between TyG-BMI and 28-day hospital mortality.</li><li style="text-align: justify; ">Below the inflection point of TyG-BMI = 380.37, each 1-SD (≈ 25.5 units) increase in TyG-BMI was linked to a 37.3% rise in 28-day hospital mortality (HR = 1.373).</li><li style="text-align: justify; ">Above 380.37, each 1-SD increase in TyG-BMI led to an 87.9% decrease in 28-day hospital mortality (HR = 0.121).</li><li style="text-align: justify; ">The log-likelihood ratio test yielded a P-value of 0.004.</li><li style="text-align: justify; ">For 28-day ICU mortality, RCS analysis showed a significant positive linear correlation with TyG-BMI.</li></ul><p style="text-align: justify; ">The researchers demonstrated that elevated TyG-BMI is significantly associated with a higher risk of short-term all-cause mortality in critically ill ischemic stroke patients in the United States. Their findings provide strong evidence to address existing uncertainties in this field, highlighting TyG-BMI as a simple and effective biomarker for identifying high-risk patients. They further emphasized that regular monitoring and managing triglycerides, blood glucose, and body weight may help reduce short-term mortality in acute IS patients or those at risk.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Ouyang, Q., Xu, L. &amp; Yu, M. Associations of triglyceride glucose-body mass index with short-term mortality in critically ill patients with ischemic stroke. Cardiovasc Diabetol 24, 91 (2025). https://doi.org/10.1186/s12933-025-02583-1</p></div><p style="text-align: justify; "><br></p>

328. RADPAD Protective Drape Reduces Radiation Exposure in Cardiac Cath Labs, Study Finds

     Wed, 30 Apr 2025 15:00:57 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/18/279017-radpad-protection-drape.webp' /><p style="text-align: justify; ">USA: A recent systematic review and meta-analysis published in the <em>Cureus </em>Journal highlights the effectiveness of the RADPAD protection drape in reducing <a href="https://medicaldialogues.in/topics/radiation-therapy">radiation exposure</a> among <a href="https://medicaldialogues.in/topics/interventional-cardiologist">interventional cardiologists</a> in<a href="https://speciality.medicaldialogues.in/topics/cath-lab"> cardiac catheterization laboratories</a>. Given the occupational hazards associated with ionizing radiation, these findings reinforce the importance of implementing protective measures to minimize health risks for healthcare professionals performing fluoroscopy-guided procedures.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">M. Chadi Alraies, Cardiology, Wayne State University Detroit Medical Center, Detroit, USA, and colleagues evaluated data from six independent studies involving 892 patients, analyzing radiation exposure levels among operators using the RADPAD protection drape compared to those without it. Ionizing radiation, a known occupational hazard in interventional cardiology, has been linked to various adverse health effects, including cataracts, skin damage, and an increased risk of malignancies. The RADPAD, a sterile, lead-free, disposable radiation shield, is designed to deflect scatter radiation away from operators, reducing their overall exposure during procedures. </p><p style="text-align: justify; "><strong>Key Findings</strong></p><p style="text-align: justify; "><strong>Reduction in Radiation Exposure</strong></p><ul><li style="text-align: justify; ">The use of the RADPAD drape significantly lowered radiation exposure for primary operators.</li><li style="text-align: justify; ">Operators using RADPAD experienced a notably lower exposure dose (OR: -0.9).</li></ul><p style="text-align: justify; "><strong>Comparable Dose Area Product (DAP) and Screening Time</strong></p><ul><li style="text-align: justify; ">There was no significant difference in the dose area product (DAP) between the RADPAD and No-RADPAD groups (OR: 0.008).</li><li style="text-align: justify; ">Screening time remained similar between both groups (OR: 0.13).</li></ul><p style="text-align: justify; "><strong>Relative Exposure Consistency</strong></p><ul><li style="text-align: justify; ">The relative exposure (E/DAP) showed no significant variation between the groups (OR: -0.47).</li></ul><p style="text-align: justify; "><strong>Protective Benefits of RADPAD</strong></p><ul><li style="text-align: justify; ">Despite no significant changes in DAP, screening time, or relative exposure, the substantial reduction in direct operator exposure underscores the protective advantage of the RADPAD drape.</li></ul><p style="text-align: justify; ">Despite these promising results, the study acknowledges certain limitations, including small sample sizes in four of the six studies analyzed. Additionally, variability in case complexity and fluoroscopy usage could have influenced the results. Another potential factor is increased operator awareness of radiation safety when using the RADPAD, which may have contributed to reduced exposure.</p><p style="text-align: justify; ">The study concludes that incorporating the RADPAD protection drape into catheterization laboratories can significantly lower scatter radiation exposure for both primary and secondary operators, regardless of procedure complexity. By reducing the risk of long-term radiation-related complications, such as cancer and cataracts, the RADPAD drape presents a practical and effective solution for enhancing radiation safety in interventional cardiology.</p><p style="text-align: justify; ">"Given the strong evidence supporting its efficacy, researchers recommend the routine use of RADPAD protective drapes in all catheterization labs. Future research with larger sample sizes and standardized protocols may further validate these findings and refine radiation protection strategies for healthcare professionals," the authors concluded. </p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Bahar A, Khanal R, Hamza M, et al. (April 28, 2024) Assessing the Efficacy of RADPAD Protection Drape in Reducing Radiation Exposure to Operators in the Cardiac Catheterization Laboratory: A Systematic Review and Meta-Analysis. Cureus 16(4): e59215. doi:10.7759/cureus.59215</p></div><p style="text-align: justify; "><br></p>

329. Laparoscopic "Tunnel" Approach Enhances Surgical Outcomes of hiatus hernia with GERD: Study

     Wed, 30 Apr 2025 15:00:28 -0000

     <img src='https://medicaldialogues.in/h-upload/2022/08/03/182507-hiatal-hernia.webp' /><p style="text-align: justify; ">A new study published in the journal of <i>BMC Surgery</i> showed that the laparoscopic "tunnel" approach significantly reduces the risk of vagus nerve injury and helps preserve perigastric vessels during surgery for hiatus hernia with gastroesophageal reflux disease (GERD). These advantages contribute to better postoperative results and improved quality of life for patients. This technique also holds promise for broader use in the treatment of hiatal hernia (HH) and GERD.</p><p style="text-align: justify; ">Achieving the best possible long-term management of reflux symptoms and indicators with little or no adverse effects is the aim of treatment for HH and GERD. The primary surgical technique for laparoscopic HH repair in conjunction with fundoplication is the traditional bilateral surgical approach (TBSA). One drawback of TBSA is that, while it can protect the vagus nerve locally during surgery, it is unable to evaluate the vagus nerve's integrity, which might result in undiscovered nerve injury. Thus, to protect the perigastric arteries and reduce vagus nerve injury, this study presents a unique laparoscopic "Tunnel" approach.</p><p style="text-align: justify; ">Clinical information was gathered sequentially from patients treated for hiatal hernia and gastroesophageal reflux illness at the First Affiliated Hospital of Ningbo University between June 2023 and June 2024 using a laparoscopic "tunnel" technique. Age, BMI, gender, DeMeester score, length of surgery, and postoperative symptoms were among the information gathered. At one, three, and six months after surgery, follow-ups were performed.</p><p style="text-align: justify; ">BMI was 25.56 ± 4.32 kg/m2, DeMeester score was 118.05 ± 17.71, GERD-Q score was 13 ± 2, and the average age was 54 ± 9 years. Nearly, 115 ± 15 minutes was the average surgery time. After surgery, symptoms dramatically decreased and after six months, the average GERD-Q score was 5 ± 1. At one month, 14 patients had dysphagia, 19 had belching, 5 had stomach distension, 16 had nausea, and 8 had diarrhea.</p><p style="text-align: justify; ">Only two patients were still belching at six months, and no other symptoms persisted. There were no reports of gallstones or vomiting. Overall, the vagus nerve damage may be less likely to occur using the laparoscopic "tunnel" technique than with the conventional surgical method. It is indisputable that maintaining function while reconstructing function is essential in the surgical treatment of functional disorders.</p><p style="text-align: justify; ">Source:</p><p style="text-align: justify; ">Feng, Z., Zhang, Z., Yan, Z., Gao, F., &amp; Chen, Q. (2025). Innovative laparoscopic “Tunnel” approach in managing hiatal hernia with gastroesophageal reflux disease: a retrospective study. BMC Surgery, 25(1), 154. <a href="https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-025-02900-1" rel="nofollow">https://doi.org/10.1186/s12893-025-02900-1</a></p>

330. PTerm Classifier promising tool for Accurately Predicting Preterm Birth: Study Finds

     Wed, 30 Apr 2025 14:45:50 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/05/27/210587-spontaneous-preterm-birth.webp' /><p style="text-align: justify; "><strong>China</strong>: In a significant advancement for prenatal care, researchers have developed a blood-based classifier called PTerm that can accurately predict the risk of preterm birth using genome-wide patterns in <a href="https://medicaldialogues.in/topics/cell-free-fetal-dna">cell-free DNA (cfDNA)</a>. This innovative tool, which leverages existing non-invasive prenatal testing (NIPT) data, offers a highly accurate and cost-effective method for early detection of at-risk pregnancies.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The findings were published online in<a href="https://speciality.medicaldialogues.in/topics/plos-medicine"> </a><em><a href="https://speciality.medicaldialogues.in/topics/plos-medicine">PLOS Medicine</a></em><a href="https://speciality.medicaldialogues.in/topics/plos-medicine"> </a>on April 15, 2025. </p><p style="text-align: justify; "><a href="https://speciality.medicaldialogues.in/topics/preterm-birth">Preterm birth (PTB)</a>—delivery before 37 weeks of gestation—remains a global challenge, affecting around 11% of pregnancies and contributing significantly to neonatal complications and maternal health risks. PTerm harnesses cfDNA, which circulates in the maternal bloodstream and reflects genetic material from the placenta and other maternal tissues. Because these DNA fragments dynamically respond to biological and pathological changes during pregnancy, they serve as a valuable biomarker for anticipating complications such as PTB.</p><p style="text-align: justify; ">To establish the model, Zhiwei Guo, Southern Medical University, Guangzhou, China, and colleagues conducted a comprehensive, multi-center study involving 2,590 pregnant women—518 with spontaneous preterm births and 2,072 with full-term deliveries—recruited from three independent hospitals. Whole-genome sequencing of plasma cfDNA was performed, focusing on promoter regions that regulate gene expression. Advanced machine learning techniques, including support vector machines and feature selection algorithms, were used to build the predictive model. </p><p style="text-align: justify; ">Key Findings:</p><ul><li style="text-align: justify; ">PTerm, the Promoter profiling classifier for preterm prediction, achieved the highest accuracy among all tested models with an AUC of 0.878 based on leave-one-out cross-validation.</li><li style="text-align: justify; ">The classifier maintained strong predictive performance across three independent validation cohorts, with a consistent AUC of 0.849, highlighting its reliability across varied populations.</li><li style="text-align: justify; ">A major benefit of PTerm is its compatibility with current non-invasive prenatal testing (NIPT) workflows, requiring no changes in procedure or additional cost.</li><li style="text-align: justify; ">Its integration into routine prenatal screening could help identify high-risk pregnancies early, enabling timely and targeted medical interventions.</li></ul><p style="text-align: justify; ">The researchers emphasized that incorporating tools like PTerm into clinical practice could enhance early risk assessment and help lower the global burden of preterm births. They hope future studies will further validate its clinical utility and encourage widespread adoption of cfDNA-based risk prediction models in obstetric care. </p><p style="text-align: justify; ">"PTerm showed strong predictive accuracy for identifying preterm birth risk. Moreover, it can be applied directly to existing non-invasive prenatal testing data without altering current procedures or incurring additional costs, making it a practical and scalable option for early screening in clinical settings," the authors concluded.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Guo Z, Wang K, Huang X, Li K, Ouyang G, Yang X, et al. (2025) Genome-wide nucleosome footprints of plasma cfDNA predict preterm birth: A case-control study. PLoS Med 22(4): e1004571. <a href="https://doi.org/10.1371/journal.pmed.1004571">https://doi.org/10.1371/journal.pmed.1004571</a></p><p style="text-align: justify; "><br></p></div><p style="text-align: justify; "><br></p>

331. Rilzabrutinib could be effective treatment option in individuals with moderate to severe chronic spontaneous urticaria: JAMA

     Wed, 30 Apr 2025 14:45:19 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/04/27/237031-chronic-utricaria.webp' /><p style="text-align: justify; ">A new study published in the <i>Journal of American Medical Association</i> showed that Rilzabrutinib decreased itching and hives while preserving a positive risk-benefit profile, indicating that it might be a useful therapy for individuals with moderate to severe chronic spontaneous urticaria (CSU) that is resistant to antihistamines.</p><p style="text-align: justify; ">The primary cause of chronic spontaneous urticaria, a skin condition, is the activation of cutaneous mast cells via a variety of pathways. B cells and mast cells contain the protein bruton tyrosine kinase (BTK), which is essential for several immune-mediated disease processes. In order to ascertain the effectiveness and risk profile of rilzabrutinib, an oral, covalent, reversible, next-generation BTK inhibitor, in the treatment of patients with CSU, Ana Giménez-Arnau and colleagues carried out this investigation.</p><p style="text-align: justify; ">A 52-week phase 2 research, the Rilzabrutinib Efficacy and Safety in CSU (RILECSU) randomized clinical trial consisted of a 12-week dose-ranging, double-blind, placebo-controlled phase that was followed by a 40-week open-label extension. From November 24, 2021, until April 23, 2024, the trial was held in 12 countries. 51 centers across Asia, North America, Europe, and South America, recruited and randomly assigned individuals. </p><p style="text-align: justify; ">Adults with moderate to severe CSU who were not effectively managed with H1-antihistamine therapy, ranging in age from 18 to 80, were enrolled in the experiment. Patients were randomized 1:1:1:1 to 400 mg of rilzabrutinib, 400 mg once a day in the evening, 800 mg twice daily, 1200 mg three times daily, or a matched placebo. Change from baseline at week 12 in either UAS7 (for non-US reference nations) or ISS7 (for the US and US reference countries) was the main end objective.</p><p style="text-align: justify; ">A total of 160 responders who were either omalizumab-naive or omalizumab-incomplete were randomly assigned. Only the 143 individuals who had never used omalizumab were part of the primary analysis population. At week 12, ISS7 and UAS7 showed significant decreases with rilzabrutinib (1200 mg/d) compared to placebo from baseline. Improvements were also seen in the weekly Angioedema Activity Score (AAS7) and weekly Hives Severity Score (HSS7).</p><p style="text-align: justify; ">As early as week 1, ISS7, HSS7, UAS7, and AAS7 showed improvements. At week 12, CSU-related biomarkers, such as immunoglobulin (Ig)-G antithyroid peroxidase, soluble Mas-related G protein–coupled receptor X2, IgG anti-Fc-ε receptor 1, and interleukin-31, were lower than placebo. Rilzabrutinib had a good risk-benefit profile; headache, nausea, and diarrhea were more common side effects with rilzabrutinib than with a placebo.</p><p style="text-align: justify; ">Overall, the findings of this clinical study support that rilzabrutinib may be a useful BTKI with a good risk-benefit profile for treating H1-antihistamine-refractory patients with CSU.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Giménez-Arnau, A., Ferrucci, S., Ben-Shoshan, M., Mikol, V., Lucats, L., Sun, I., Mannent, L., &amp; Gereige, J. (2025). Rilzabrutinib in antihistamine-refractory chronic spontaneous urticaria: The RILECSU phase 2 randomized clinical trial. JAMA Dermatology (Chicago, Ill.). <a href="https://jamanetwork.com/journals/jamadermatology/fullarticle/2833141?guestAccessKey=54f615a1-9410-4460-b05e-8074672b07e9&amp;utm_source=silverchair&amp;utm_medium=email&amp;utm_campaign=article_alert-jamadermatology&amp;utm_content=olf&amp;utm_term=042325&amp;adv=000002993726" rel="nofollow">https://doi.org/10.1001/jamadermatol.2025.0733</a></p>

332. Obesity Linked to Higher Complications and Longer Recovery in Joint Replacement Surgery: Study Finds

     Wed, 30 Apr 2025 14:30:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/22/275441-joint-replacement.webp' /><p style="text-align: justify; ">Pakistan: A recent comparative study has shed light on the significant impact of <a href="https://medicaldialogues.in/topics/obesity">obesity </a>on<a href="https://medicaldialogues.in/topics/joint%20replacement%20surgery/"> joint replacement surgery</a> outcomes. The findings revealed that obesity significantly worsened postoperative outcomes in patients undergoing joint replacement surgery (OR: 2.40).</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">"Patients with a BMI over 30 kg/m² had a higher prevalence of severe <a href="https://medicaldialogues.in/topics/osteoarthritis">osteoarthritis </a>(45% vs. 27%), required longer hospital stays (7.6 vs. 5.4 days), and faced nearly triple the risk of surgical site infections," the researchers reported. The results, published in the journal <em>Cureus, </em>highlight the importance of careful surgical planning and enhanced postoperative care for obese patients to improve recovery and reduce complications. </p><p style="text-align: justify; ">The researchers note that joint replacement surgery is a common procedure aimed at restoring function and alleviating pain in patients with severe arthritis or joint damage. However, a patient’s weight plays a crucial role in surgical outcomes. Excess body weight adds stress to the joints and affects the healing process after surgery. Obesity further complicates the procedure, leading to increased surgical challenges, delayed recovery, and less favorable outcomes.</p><p style="text-align: justify; ">Against the above background, Abdul Rahman, Orthopaedic Surgery Unit One, Jinnah Hospital Lahore, Allama Iqbal Medical College, Lahore, PAK, and colleagues seek to evaluate how obesity affects postoperative outcomes in joint replacement surgery by comparing outcomes between obese and non-obese patients. </p><p style="text-align: justify; ">For this purpose, the researchers conducted a prospective observational study from January 2022 to December 2023, including 186 patients—93 obese (BMI &gt; 30 kg/m²) and 93 non-obese (BMI &lt; 30 kg/m²). They collected data on postoperative complications, mobility, pain scores, comorbidities, and demographics. Statistical analysis was performed using IBM SPSS Statistics Version 25.0, and multivariate logistic regression was applied to identify independent predictors of adverse outcomes. </p><p style="text-align: justify; ">The study led to the following findings:</p><ul><li style="text-align: justify; ">The average BMI was significantly higher in obese patients (34.8 vs. 24.6 kg/m²).</li><li style="text-align: justify; ">Severe osteoarthritis was more common in obese patients (45.16% vs. 26.88%).</li><li style="text-align: justify; ">Obese patients had longer hospital stays (7.6 vs. 5.4 days).</li><li style="text-align: justify; ">Postoperative complications, including surgical site infections, were more frequent in obese patients (11.83% vs. 4.30%).</li><li style="text-align: justify; ">Obesity was identified as an independent predictor of poor postoperative outcomes (OR: 2.40).</li></ul><p style="text-align: justify; ">The findings revealed that obese patients experienced higher rates of postoperative complications, greater pain, reduced mobility, and longer hospital stays, underscoring the significant negative impact of obesity on joint replacement outcomes. Obesity, along with diabetes mellitus and poor preoperative mobility, emerged as an independent predictor of adverse postoperative results, including a higher risk of surgical site infections, delayed wound healing, prosthetic loosening, and revision surgery.</p><p style="text-align: justify; ">"These findings highlight the need for personalized preoperative assessments, optimized perioperative care, and targeted rehabilitation strategies to improve surgical outcomes and enhance long-term recovery in obese patients." the authors concluded.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Rahman A, Abid Hasan H, Ali R, et al. (March 15, 2025) Impact of Obesity on Joint Replacement Surgery Outcomes: A Comparative Study. Cureus 17(3): e80623. doi:10.7759/cureus.80623</p><p style="text-align: justify; "> </p></div><p style="text-align: justify; "><br></p>

333. Govt Issues Export Guidelines for Doxycycline 100 mg Dispersible Tablets

     Wed, 30 Apr 2025 13:59:20 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/06/07/240456-medicine-6.webp' /><p style="text-align: justify; "><b>New Delhi:</b> The Directorate General of Foreign Trade (DGFT), under the Ministry of Commerce and Industry, has issued Public Notice No. 03/2025-26 dated April 24, 2025, formally notifying a new Standard Input Output Norm (SION) under the Chemicals &amp; Allied Products (Product Group A) for Doxycycline 100 mg Dispersible Tablets.</p><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify;">The SION, now listed under serial number A-3685, has been introduced to streamline export processes and establish standardized input-output parameters for the formulation. The notice has been issued in exercise of powers conferred under Paragraph 1.03 of the Foreign Trade Policy, 2023, as amended from time to time.</p><p style="text-align: justify;"><b>Key Inputs and Output Norms as per DGFT SION A-3685:</b></p><div class="pasted-from-word-wrapper"><table class="TableGrid" border="0" cellspacing="0" cellpadding="0" width="609" style="text-align: justify;"><tbody><tr><td width="214" valign="top"><p><b>Export Product</b></p></td><td width="76" valign="top"><p><b>Qty.</b></p></td><td width="48" valign="top"><p><b>Sl. No.</b></p></td><td width="165" valign="top"><p><b>Import Items</b></p></td><td width="106" valign="top"><p><b>Qty. allowed.</b></p></td></tr><tr><td width="214" valign="top"><p>Doxycycline 100 mg. Dispersible Tablets (Eq. to Anhydrous Doxycycline 100 mg.)</p></td><td width="76" valign="top"><p>1 Number Tablet</p></td><td width="48" valign="top"><p>I</p></td><td width="165" valign="top"><p>Doxycycline Monohydrate U.S.P/B.P</p></td><td width="106" valign="top"><p>106.13 mg.</p></td></tr></tbody></table></div><p style="text-align: justify;">According to the DGFT notification, “The following Standard Input Output Norms (SION) is included in the Handbook of Procedures, 2023 under Appendix 4B, as under:”</p><p style="text-align: justify;">The SION is likely to boost competitiveness for Indian exporters catering to global antibiotic markets, particularly in low- and middle-income countries where demand for affordable dispersible antibiotic tablets remains strong.</p><p style="text-align: justify;">The notification has come into immediate effect from the date of issue.</p><p style="text-align: justify;"><i><b>To view the official DGFT public notice, click on the link below:</b></i></p><div class="hocal-draggable" style="text-align: justify; " draggable="true"><a href="https://medicaldialogues.in/pdf_upload/pn-3-english-285021.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/pn-3-english-285021.pdf</a></div></div></div><div class="pasted-from-word-wrapper"></div>

334. Centre boosts NEET 2025 security; DMs, SPs roped in to prevent irregularities

     Wed, 30 Apr 2025 13:00:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285032-mdtv-2025-04-30t153250809.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p>In a bid to ensure the smooth and secure conduct of NEET UG 2025, the Ministry of Education is holding a series of meetings with district magistrates (DMs) and superintendents of police (SPs) across all states and Union territories. The move comes as part of a comprehensive strategy to avoid any lapses during the exam, scheduled for May 4, in the wake of last year’s controversies involving paper leaks and irregularities.</p><div class="inside-post-ad-1 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_1"></div></div><div class="pasted-from-word-wrapper"><p data-start="525" data-end="864" class="">The medical entrance exam, which over 23 lakh candidates are expected to take this year, will be held in more than 550 cities at over 5,000 centres nationwide. Officials have activated district-level coordination committees and rolled out multi-layered security measures, aiming to make the exam process "fool-proof"</p></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><i><a href="https://medicaldialogues.in/health-news/nmc/nmc-allows-delhi-medical-council-to-relax-stipend-condition-give-internship-posting-to-fmgs-at-mcd-hospitals-147490#:~:text=Although,%20the%20Apex%20Medical%20Commission,to%20provide%20stipend%20by%20the"></a></i></div><div></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><i><a href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471"></a></i></div><div></div></div><div class="pasted-from-word-wrapper"><div></div></div><p><i><b>For more information, click on the link below:</b></i></p><div class="pasted-from-word-wrapper"><div><i><a href="https://medicaldialogues.in/news/education/after-last-years-irregularities-centre-tightens-neet-2025-security-net-147478"><b>After Last Year's Irregularities, Centre Tightens NEET 2025 Security Net</b></a></i></div><div></div></div><div class="pasted-from-word-wrapper"></div></div>

335. NMC allows Delhi Medical Council to relax stipend rule, permit FMG internships at MCD hospitals

     Wed, 30 Apr 2025 12:46:27 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285031-mdtv-2025-04-30t153134019.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Taking cognisance of the difficulties faced by the <a href="https://medicaldialogues.in/topics/Foreign-medical-graduates">Foreign Medical Graduates </a>(FMGs) to complete their one-year compulsory rotating internship training in Delhi, the <a href="https://medicaldialogues.in/topics/NMC">National Medical Commission</a> (NMC) has agreed to Delhi Medical Council's proposal to relax the condition to pay stipend to medical graduates from abroad, who are willing to forgo the stipend.</p><p style="text-align: justify;">Although, the Apex Medical Commission acknowledged that as per FMGL Regulations, 2021, grant of stipend to interns is a State matter and NMC only is a regulatory body, it decided to relax the stipend conditions while keeping in view the best interest of students and financial implication to provide stipend by the <a href="https://medicaldialogues.in/topics/municipal-corporations">Municipal Corporation of Delhi</a> (MCDs).</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/health-news/nmc/nmc-allows-delhi-medical-council-to-relax-stipend-condition-give-internship-posting-to-fmgs-at-mcd-hospitals-147490#:~:text=Although,%20the%20Apex%20Medical%20Commission,to%20provide%20stipend%20by%20the"><b>NMC allows Delhi Medical Council to relax stipend condition, give internship posting to FMGs at MCD Hospitals</b></a></i></div><div></div></div><div class="pasted-from-word-wrapper"></div></div>

336. Revise study protocol: CDSCO Panels tells Lupin on Ranibizumab Solution for Injection 10 mg/mL

     Wed, 30 Apr 2025 12:30:39 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/24/279930-lupin-digital-health-50-5.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; "><b>New Delhi:</b> Responding to the drug major Lupin's proposal to conduct phase IV clinical trial of the ophthalmic drug Ranibizumab Solution for Injection 10 mg/ml, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organization (CDSCO) has opined that to revise the study protocol.</p><p style="text-align: justify; ">This came after the firm presented the proposal to conduct a Phase IV clinical trial titled “A multicenter, open-label, prospective, single-arm, non-comparative, non-randomized phase IV study to evaluate safety and efficacy of Injection Ranibizumab (of Sponsor Lupin Limited) given as an intravitreal injection in preterm infants with Retinopathy of Prematurity” vide Protocol No. 24-VIN-0299; Version No. 01; Dated: 05th September, 2024 with the few changes in the protocol.</p><p style="text-align: justify; ">Ranibizumab is a medication used to treat various eye conditions, primarily those involving abnormal blood vessel growth, such as wet age-related macular degeneration (AMD) and diabetic macular edema. It is a recombinant humanized monoclonal antibody fragment that binds to and inhibits vascular endothelial growth factor A (VEGF-A), a protein that stimulates new blood vessel formation.</p><p style="text-align: justify; ">It is a recombinant humanized monoclonal antibody fragment that binds to and inhibits vascular endothelial growth factor A (VEGF-A), a protein that stimulates new blood vessel formation</p><p style="text-align: justify; ">At the recent SEC meeting for Ophthalmology held on 19th March 2025, the expert panel reviewed the proposal to conduct a Phase IV clinical trial to evaluate the safety and efficacy of Injection Ranibizumab (of sponsor Lupin Limited) given as an intravitreal injection in preterm infants with retinopathy of prematurity.</p><p style="text-align: justify; ">After detailed deliberation, the committee recommended to conduct the study with the following changes in the protocol:-</p><blockquote><div style="text-align: justify;">1. Proper, detailed study methodology should be provided and SOP should be a part of the study design.</div><div style="text-align: justify;">2. Perkins tonometer should be used for measurement of IOP. If IOP is raised, then a small parenthesis should be performed.</div><div style="text-align: justify;">3. Study should include pre-term infants with natural spontaneous breathing/normal breathing only.</div><div style="text-align: justify;">4. Micro-ROPLAS test should be performed at screening to exclude congenital NLDO.</div><div style="text-align: justify;">5. Echo test should be performed at screening if an abnormality in the ECG is suspected.</div><div style="text-align: justify;">6. If both the eyes are eligible for the study treatment as per the inclusion criteria, treatment should be providedsimultaneously.</div></blockquote><p style="text-align: justify; ">In line with the above, the expert panel suggested that the firm shall submit the revised protocol to CDSCO for further evaluation.</p><p style="text-align: justify; ">Also Read: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/cdsco-panel-rejects-akums-drugs-proposal-for-pkpd-study-of-cholecalciferol-aqueous-injection-147393">CDSCO panel rejects Akums Drugs Proposal for PK/PD study of Cholecalciferol aqueous injection</a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

337. Rs 10 lakh health insurance for senior citizens in Delhi

     Wed, 30 Apr 2025 12:30:17 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285034-mdtv-2025-04-30t154041540.webp' /><div class="pasted-from-word-wrapper"><div class="article-text-desc entry-content clearfix single-post-content"><div id="post-content-inner" class="row post-content-inner"><div class="details-content-story"><div><div class="story"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">A boon for senior citizens, the <a href="https://medicaldialogues.in/state-news/delhi">Delhi </a>government has officially launched the Ayushman Vay Vandana Scheme, offering comprehensive health insurance coverage of up to Rs 10 lakh annually to all senior citizens aged 70 years and above.</p><p style="text-align: justify;">Chief Minister Rekha Gupta, in collaboration with Union Minister Hardeep Singh Puri, formally inaugurated the scheme at a launch event in the capital. The first batch of Vay Vandana health cards was distributed to senior citizens, marking the rollout of this ambitious health initiative.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/health/ayushman-vay-vandana-delhi-launches-rs-10-lakh-health-cover-for-senior-citizens-147480"><b>Ayushman Vay Vandana: Delhi launches Rs 10 lakh health cover for Senior Citizens</b></a></i></div></div></div></div></div></div></div><div class="entry-terms post-tags clearfix"></div></div>

338. Doctors can't face criminal cases for prescribing costlier drugs: HC

     Wed, 30 Apr 2025 12:15:31 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285030-mdtv-2025-04-30t152748191.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Observing that prescribing any chemo drug or medicine to any patient is the sole prerogative and expertise of the treating doctor, the <a href="https://medicaldialogues.in/topics/odisha-high-court">Orissa High Court </a>recently quashed criminal proceedings against a doctor, who was accused of showing undue favour to various <a href="https://medicaldialogues.in/topics/pharmaceutical-companies">pharmaceutical companies</a> and prescribing costlier medicines to the patients suffering from cancer.</p><p style="text-align: justify;">The HC bench comprising Justice Aditya Kumar Mohapatra held that a doctor should not be held criminally liable for prescribing any particular drug of any pharma company unless the said drug(s) are hazardous, non-standard or substandard quality/brand, or restricted by the appropriate Authority of the Government.</p></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471"><b>Criminal cases cannot be lodged against Doctors because they prescribed costlier drugs: HC</b></a></i></div><div></div></div><div class="pasted-from-word-wrapper"></div></div>

339. After NMC Order, MBBS Admissions of 2 Students Cancelled over NEET 2024 malpractice

     Wed, 30 Apr 2025 12:07:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285015-mbbs-admission-cancelled.webp' /><p style="text-align: justify; "><b>Karnataka- </b>Following an order from the National Medical Commission (<a href="https://medicaldialogues.in/topics/nmc">NMC</a>), <a href="https://medicaldialogues.in/topics/mbbs">MBBS </a>admissions for two students have been cancelled due to irregularities in the National Eligibility and Entrance Test-Undergraduate (NEET UG) 2024 medical entrance exam.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">One of these students was studying at Kempegowda Institute of Medical Sciences, Bengaluru, while the other was studying at AJ Institute of Medical Sciences, Mangaluru. Both students had taken seats in the management quota. In February, after the NMC notification, the Karnataka Examination Authority (KEA) informed Mangaluru Medical College; KIMS received the letter last week.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/karnataka-warns-govt-doctors-against-private-practice-during-duty-hours-147243"><b>Also Read:&nbsp;</b>Karnataka warns Govt doctors against private practice during duty hours</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">According to a <a href="https://timesofindia.indiatimes.com/city/bengaluru/neet-2024-malpractice-mbbs-admissions-of-2-girls-in-karnataka-cancelled/articleshow/120740170.cms" target="_blank" rel="nofollow">TOI </a>media report, on April 23, KEA wrote to the principal of KIMS informing that KEA had cancelled the seat allotted to the student. The college was asked to relieve the candidate and inform NMC and KEA.</p></div><div class="pasted-from-word-wrapper">The NMC letter to KEA stated that "… the MBBS student in your state was found to be involved in malpractices as reported by the Central Bureau of Investigation, which was entrusted with the responsibility of investigating the paper leak cases of NEET (UG) 2024. In this regard, you are requested to discharge this candidate or cancel their admission from your respective colleges in light of the CBI report."</div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">Meanwhile, speaking to the TOI in this regard, KEA executive director H Prasanna said, "This should be an eye-opener for the students. Even if they are not caught initially, sooner or later, it will be found that the students had used malpractices to get admission".</p><p dir="ltr" style="text-align: justify; ">Medical Dialogues had earlier reported that authorities of Dr Sampurnanand Medical College, Jodhpur, Rajasthan, suspended two MBBS students for allegedly appearing as dummy candidates in the National Eligibility and Entrance Test-Undergraduate (NEET UG) 2024.</p></div><div class="pasted-from-word-wrapper"><p dir="ltr">Last year, the NEET exam for the academic year 2024 was held on May 5, which stirred up a lot of controversy due to certain anomalies, including several students scoring impossible full marks, the exam being announced on the day of the Lok Sabha election results much before the scheduled date, and toppers reportedly being from the same exam centre.</p><p dir="ltr">Around 24 lakh candidates had appeared for <a href="https://medicaldialogues.in/topics/neet-ug-2024" target="_blank">NEET UG 2024</a> . The prestigious exam was mired in controversy due to discrepancies. Meanwhile, students reported that the centre gave them question papers with pre-marked answers, then withdrew them. However, the <a href="https://medicaldialogues.in/topics/nta" target="_blank">NTA</a>, which conducts the exam, said it re-examined over 100 candidates.</p></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/karnataka-govt-enforces-strict-duty-hours-bans-private-practice-for-doctors-147161" style="background-color: rgb(255, 255, 255);"><b>Also Read:&nbsp;</b>Karnataka Govt enforces strict duty hours, bans private practice for doctors</a></p></div><div class="pasted-from-word-wrapper"><div></div></div>

340. Kerala: Doctor couple under scrutiny for alleged duty swap

     Wed, 30 Apr 2025 11:51:45 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/03/15/204890-doctor.webp' /><p style="text-align: justify; "><b>Malappuram: </b>A doctor couple is facing serious allegations after the Vigilance and Anti-Corruption Bureau (VACB) found that a female doctor posted at a government hospital, was allegedly swapping duties with her husband, a private doctor and treating patients without permission. &nbsp;&nbsp;</p><p style="text-align: justify; ">The incident took place at Government Taluk Hospital, Tirurangadi, where the husband doctor was allegedly treating patients in place of his wife. Following this, the VCB has directed the Health Department to initiate appropriate action against the doctor couple.&nbsp;</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/doctors/fir-against-2-doctors-for-forging-documents-to-frame-colleague-as-quack-147501" target="_blank">FIR against 2 doctors for forging documents to frame colleague as Quack</a></b></p><p style="text-align: justify; ">According to VACB officials, the doctor, who runs a private clinic, was seen attending to patients at the Government Taluk Hospital in Tirurangadi in place of his wife, Dr. Sahita, who is posted there. He allegedly took her place several times without any official approval.</p><p style="text-align: justify; ">According to a latest media report by<a href="https://www.thehindu.com/news/national/kerala/vacb-recommends-action-against-doctor-couple-in-malappuram/article69506060.ece" rel="nofollow"> The Hindu,</a> the matter came to light after the High Court lawyer Kulathur Jaising filed a complaint with the Vigilance Bureau. Following this, the agency carried out an investigation and confirmed the complaint was true. Now, they have asked the Health Department to take proper action against the doctor couple.</p><p style="text-align: justify; ">A doctor who is not employed at a government hospital but is treating patients there without permission is a serious violation of government rules.&nbsp;</p><p style="text-align: justify; ">Medical Dialogues had previously reported that a female doctor posted at the Emergency Medical Department at Tirurangadi Taluk Hospital has been accused of swapping her duties with her husband, who is also a doctor, while she was breastfeeding her newborn at the hospital. The husband is reported to have taken over the emergency duties, including consultation and medical examinations, in her absence.</p><p style="text-align: justify; ">The couple's unconventional duty adjustment sparked a heated controversy, with a youth organisation- the Muslim Youth League activists demanding an investigation into the matter. They filed a complaint with Health Minister Veena George and the District Medical Officer (DMO).&nbsp;</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/amp/news/health/doctors/controversy-erupts-after-doctor-allegedly-swaps-duties-with-husbandat-govt-hospital-143839" target="_blank"> Controversy erupts after doctor allegedly swaps duties with husband at Govt hospital</a></b><br></p>

341. Health Bulletin 30/ April/ 2025

     Wed, 30 Apr 2025 11:37:43 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285024-health-bulletin-2025-04-30t151806954.webp' /><p style="text-align: justify; "><b>Here are the top health news for the day:</b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Doctors can't face criminal cases for prescribing costlier drugs: HC</b></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">Observing that prescribing any chemo drug or medicine to any patient is the sole prerogative and expertise of the treating doctor, the <a href="https://medicaldialogues.in/topics/odisha-high-court">Orissa High Court </a>recently quashed criminal proceedings against a doctor, who was accused of showing undue favour to various <a href="https://medicaldialogues.in/topics/pharmaceutical-companies">pharmaceutical companies</a> and prescribing costlier medicines to the patients suffering from cancer.</p><p style="text-align: justify;">The HC bench comprising Justice Aditya Kumar Mohapatra held that a doctor should not be held criminally liable for prescribing any particular drug of any pharma company unless the said drug(s) are hazardous, non-standard or substandard quality/brand, or restricted by the appropriate Authority of the Government.</p></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471">Criminal cases cannot be lodged against Doctors because they prescribed costlier drugs: HC</a></i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>NMC allows Delhi Medical Council to relax stipend rule, permit FMG internships at MCD hospitals</b></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">Taking cognisance of the difficulties faced by the <a href="https://medicaldialogues.in/topics/Foreign-medical-graduates">Foreign Medical Graduates </a>(FMGs) to complete their one-year compulsory rotating internship training in Delhi, the <a href="https://medicaldialogues.in/topics/NMC">National Medical Commission</a> (NMC) has agreed to Delhi Medical Council's proposal to relax the condition to pay stipend to medical graduates from abroad, who are willing to forgo the stipend.</p><p style="text-align: justify;">Although, the Apex Medical Commission acknowledged that as per FMGL Regulations, 2021, grant of stipend to interns is a State matter and NMC only is a regulatory body, it decided to relax the stipend conditions while keeping in view the best interest of students and financial implication to provide stipend by the <a href="https://medicaldialogues.in/topics/municipal-corporations">Municipal Corporation of Delhi</a> (MCDs).</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/health-news/nmc/nmc-allows-delhi-medical-council-to-relax-stipend-condition-give-internship-posting-to-fmgs-at-mcd-hospitals-147490#:~:text=Although%2C%20the%20Apex%20Medical%20Commission,to%20provide%20stipend%20by%20the">NMC allows Delhi Medical Council to relax stipend condition, give internship posting to FMGs at MCD Hospitals</a></i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Centre boosts NEET 2025 security; DMs, SPs roped in to prevent irregularities</b></div></div><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify;"> In a bid to ensure the smooth and secure conduct of NEET UG 2025, the Ministry of Education is holding a series of meetings with district magistrates (DMs) and superintendents of police (SPs) across all states and Union territories. The move comes as part of a comprehensive strategy to avoid any lapses during the exam, scheduled for May 4, in the wake of last year’s controversies involving paper leaks and irregularities.</p><div class="inside-post-ad-1 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_1"></div></div><div class="pasted-from-word-wrapper"><p data-start="525" data-end="864" class="" style="text-align: justify;">The medical entrance exam, which over 23 lakh candidates are expected to take this year, will be held in more than 550 cities at over 5,000 centres nationwide. Officials have activated district-level coordination committees and rolled out multi-layered security measures, aiming to make the exam process "fool-proof"</p></div></div><div class="pasted-from-word-wrapper"><div><b></b></div><div></div></div><div class="pasted-from-word-wrapper"><div><b><i><a href="https://medicaldialogues.in/health-news/nmc/nmc-allows-delhi-medical-council-to-relax-stipend-condition-give-internship-posting-to-fmgs-at-mcd-hospitals-147490#:~:text=Although%2C%20the%20Apex%20Medical%20Commission,to%20provide%20stipend%20by%20the"></a></i></b></div><div></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><b><i><a href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471"></a></i></b></div><div></div></div><div class="pasted-from-word-wrapper"><div></div></div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/news/education/after-last-years-irregularities-centre-tightens-neet-2025-security-net-147478">After Last Year's Irregularities, Centre Tightens NEET 2025 Security Net</a></i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Rs 10 lakh health insurance for senior citizens in Delhi</b></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">A boon for senior citizens, the <a href="https://medicaldialogues.in/state-news/delhi">Delhi </a>government has officially launched the Ayushman Vay Vandana Scheme, offering comprehensive health insurance coverage of up to Rs 10 lakh annually to all senior citizens aged 70 years and above.</p><p style="text-align: justify;">Chief Minister Rekha Gupta, in collaboration with Union Minister Hardeep Singh Puri, formally inaugurated the scheme at a launch event in the capital. The first batch of Vay Vandana health cards was distributed to senior citizens, marking the rollout of this ambitious health initiative.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify; "><b><i><a href="https://medicaldialogues.in/news/health/ayushman-vay-vandana-delhi-launches-rs-10-lakh-health-cover-for-senior-citizens-147480">Ayushman Vay Vandana: Delhi launches Rs 10 lakh health cover for Senior Citizens</a></i></b></div></div>

342. NEET 2025 Admit Cards Released! Download NOW

     Wed, 30 Apr 2025 11:19:14 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285045-neet-ug-2025-admit-card.webp' /><p style="text-align: justify; "><b>New Delhi- </b>The National Testing Agency (NTA) has released the admit cards for the National Eligibility and Entrance Test-Undergraduate (NEET UG) entrance exam 2025. The registered candidates can download their hall tickets from the official website of NTA.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">NTA is going to conduct NEET UG 2025 on May 4, 2025. The city slip was released on April 23. Meanwhile, candidates should note that the NEET 2025 admit card is only available in the online mode on the official website, and no hard copy will be issued to any candidate under any circumstances. </p><p dir="ltr" style="text-align: justify; ">The NEET admit card 2025 is an important document to be carried to the exam centre. Therefore, students are advised to read the information given in the hall ticket carefully and make sure that they bring the correct information about themselves.&nbsp;</p></div><div class="pasted-from-word-wrapper" style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-aadhaar-confusion-sparks-panic-days-before-exam-147516"><b>Also Read:&nbsp;</b>NEET 2025: Aadhaar Verification Confusion Sparks Panic Days Before Exam</a></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; "><b><u><i>The NEET UG 2025 admit card includes the following important details for the appearing candidates- </i></u></b></p><p style="text-align: justify; ">1 NEET UG exam date and time </p><p style="text-align: justify; ">2 Reporting time and gate closing time </p><p style="text-align: justify; ">3 Duration of the exam </p><p style="text-align: justify; ">4 Examination centre address and code </p><p style="text-align: justify; ">5 Exam city </p><p style="text-align: justify; ">6 Language of the question paper. </p><p style="text-align: justify; ">7 Candidate’s name </p><p style="text-align: justify; ">8 Roll number </p><p style="text-align: justify; ">9 Application number </p><p style="text-align: justify; ">10 Date of birth </p><p style="text-align: justify; ">11 Gender </p><p style="text-align: justify; ">12 Category (General, SC, ST, OBC, etc.) </p><p style="text-align: justify; ">13 PwD status (if applicable) </p><p style="text-align: justify; ">14 Candidate’s photograph (as uploaded in the application) </p><p style="text-align: justify; ">15 Candidate’s signature.</p><p dir="ltr" style="text-align: justify; "><b><u>STEPS TO DOWNLOAD THE NEET UG 2025 HALL TICKETS</u></b></p><p dir="ltr" style="text-align: justify; "><b>STEP 1-</b> Go to the official website of NTA.</p><p dir="ltr" style="text-align: justify; "><b>STEP 2-</b> On the homepage, click on the NEET UG admit card link.</p><p dir="ltr" style="text-align: justify; "><b>STEP 3-</b> Now, log in using your application number and date of birth.</p><p dir="ltr" style="text-align: justify; "><b>STEP 4-</b> NEET exam admit card will open up on the screen.</p><p dir="ltr" style="text-align: justify; "><b>STEP 5-</b> Download and take a printout of the hall ticket.</p><p dir="ltr" style="text-align: justify; "><b>STEP 6-</b> Make sure to carry the same to the exam hall.</p><p dir="ltr" style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-nta-notifies-advance-intimation-of-exam-city-for-candidates-147214" style="background-color: rgb(255, 255, 255);"><b>Also Read:&nbsp;</b>NEET 2025: NTA notifies Advance Intimation of Exam City for candidates</a></p></div><div class="pasted-from-word-wrapper"><div></div></div>

343. Gland Pharma bags USFDA nod for glaucoma drug

     Wed, 30 Apr 2025 11:10:46 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/06/06/240293-glaucoma.webp' /><p><span style="background-color: rgb(255, 255, 255); text-align: justify;"><b>Hyderabad:&nbsp;</b><a href="https://medicaldialogues.in/topics/gland-pharma">Gland Pharma Limited</a>,&nbsp;a generic injectable &amp; ophthalmic focused pharmaceutical company, has announced that the company has received approval from the United States Food and Drug Administration (USFDA) for its Abbreviated New Drug Application for Latanoprostene Bunod Ophthalmic Solution,0.024%.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">The Product is bioequivalent and therapeutically equivalent to the reference listed drug (RLD), VYZULTA Ophthalmic solution, 0.024%, of Bausch and Lomb, Inc.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> This Product is indicated for the reduction of intraocular pressure (IOP) in patients with open-angle </span><a href="https://medicaldialogues.in/topics/glaucoma">glaucoma</a>&nbsp;<span style="background-color: rgb(255, 255, 255);">or ocular hypertension.&nbsp;</span>Open-angle glaucoma is the most common type of glaucoma, a group of eye conditions that damage the optic nerve, often due to elevated intraocular pressure (IOP).&nbsp;</p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> Gland Pharma is the exclusive First-to-File and is eligible for 180 days of generic drug exclusivity.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> According to IQVIA, the product had US sales of approximately USD 171 million for the twelve months ending February.</span></p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/aurobindo-pharma-dr-reddys-labs-and-4-others-partner-with-telangana-to-set-up-facilities-in-pharma-city-138825">Aurobindo Pharma, Dr Reddy's Labs and 4 others partner with Telangana to set up facilities in Pharma City</a></i></b></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Medical Dialogues team had earlier reported that&nbsp;</span>Gland Pharma had received approval from the USFDA for Latanoprost Ophthalmic Solution, 0.005% (2.5 mL Fill) for high eye pressure/intraocular pressure (IOP) in patients with openangle glaucoma or ocular hypertension.</p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/gland-pharma-receives-usfda-nod-for-pain-management-injection-acetaminophen-145974">Gland Pharma receives USFDA nod for pain management injection Acetaminophen</a></i></b></p><div class="pasted-from-word-wrapper"><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><p style="text-align: justify; ">Gland Pharma was established in 1978 in Hyderabad and has grown over the years from a contract manufacturer of small-volume liquid parenteral products to become a injectable-focused company with a global footprint across 60 countries, including the United States, Europe, Canada, Australia, India, and other markets. It operates primarily under a business-to-business (B2B) model and develops, manufactures, and market sterile injectables. It has a wide range of injectables, including vials, ampoules, pre-filled syringes, lyophilized vials, dry powders, infusions, oncology, and ophthalmic solutions.</p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/gland-pharma-vice-president-strategy-investments-investor-relations-ankit-gupta-tenders-resignation-139166">Gland Pharma Vice President (Strategy, Investments &amp; Investor Relations) Ankit Gupta tenders resignation</a></i></b></p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; "><br></p></div>

344. Medical Bulletin 30/ April/ 2025

     Wed, 30 Apr 2025 11:01:41 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285029-sleep-47.webp' /><p style="text-align: justify; "><b>Here are the top medical news for the day:</b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify; "><b>Study Links Rising Prediabetes in Youth to Increased Heart Risks and Early Cardiovascular Damage</b></div><div style="text-align: justify; ">A groundbreaking study from the University of Bristol’s Children of the 90s cohort has revealed alarming trends in the health of adolescents transitioning to young adulthood. The study tracked 1,595 participants from ages 17 to 24, assessing the prevalence of prediabetes and its effects on heart health. Using two different fasting blood glucose cutpoints (≥5.6 mmol/L and ≥6.1 mmol/L), researchers found a significant increase in prediabetes, with 6.2% of 17-year-olds exhibiting fasting blood sugar ≥5.6 mmol/L, rising to 26.9% by age 24.</div><div style="text-align: justify;">The study also noted a threefold increase in the prevalence of left ventricular hypertrophy (LVH) from 2.4% at age 17 to 7.1% at 24. "Even healthy-looking adolescents may be on a path toward cardiovascular diseases due to high blood glucose and insulin resistance," said Andrew Agbaje, associate professor at the University of Eastern Finland.</div><div style="text-align: justify;">The findings highlight a troubling link between persistently high blood glucose and heart dysfunction, particularly in females, where the damage to heart function occurred five times faster than in males. Insulin resistance was also associated with a 10% increased risk of premature heart damage. The study underscores the importance of early intervention and lifestyle changes, especially as adolescents gain independence from family influences.</div><div style="text-align: justify; ">This research, the largest of its kind, stresses the critical need for awareness and prevention of cardiometabolic diseases in youth, particularly in light of the rising prevalence of prediabetes.</div><div style="text-align: justify;">Reference: Agbaje, A. O., et al. (2025) Persistent Hyperglycemia and Insulin Resistance with the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care. doi.org/10.2337/dc24-2459.</div><div></div><div style="text-align: justify; "><b>56 Risk Factors Identified That Could Prevent 63% of Sudden Cardiac Arrest Cases, Study Finds</b></div><div style="text-align: justify; ">A new study published in the Canadian Journal of Cardiology reveals that 56 non-clinical risk factors, including lifestyle, physical measures, psychosocial factors, and environmental influences, could help prevent up to 63% of sudden cardiac arrest (SCA) cases. SCA, a leading cause of death worldwide, claims about 60,000 lives annually in Canada alone. The study's lead author, Huihuan Luo, PhD, of Fudan University, emphasizes that improving modifiable risk factors, especially lifestyle habits, can significantly reduce SCA risk.</div><div style="text-align: justify;">Using an exposome-wide association study combined with Mendelian randomization, the research uncovered surprising findings. It found that eliminating the worst 40%–63% of risk factors, particularly lifestyle-related ones, could prevent a substantial portion of SCA cases. Factors like positive mood, weight management, blood pressure control, and even moderate champagne or white wine consumption emerged as protective elements. "Surprisingly, higher consumption of champagne and white wine showed a cardioprotective effect, challenging the notion that only red wine offers these benefits," said Nicholas Grubic, MSc, and Dakota Gustafson, PhD, in the accompanying editorial.</div><div style="text-align: justify;">The study also revealed an inverse relationship between computer use and SCA risk, though further analysis clarified that this likely reflects socioeconomic or occupational differences rather than a direct protective effect.</div><div style="text-align: justify;">The researchers stress the importance of transitioning from reactive to preventive strategies to reduce the SCA burden, particularly in resource-limited settings. Identifying and targeting modifiable factors could lead to significant improvements in public health outcomes.</div><div style="text-align: justify;">References: Establishment and Validation of Prediction Models for Non-curative Resection After ESD for Early Gastric Cancer</div><div style="text-align: justify; "><b>Sound Wave Therapy Targets Amygdala to Relieve Depression, Anxiety, and PTSD Symptoms</b></div><div style="text-align: justify; ">New research from Dell Medical School at The University of Texas at Austin introduces a groundbreaking treatment for patients suffering from depression, anxiety, and trauma-related disorders. The study, published in Molecular Psychiatry, explores the use of low-intensity focused ultrasound technology to safely and effectively modulate deep brain activity. This approach targets the amygdala, the brain region known for its role in mood and anxiety disorders, without the need for surgery or invasive procedures.</div><div style="text-align: justify;">In a double-blind study, 29 patients with various mood and anxiety disorders underwent MRI-guided focused ultrasound treatment on the left amygdala. After three weeks of daily treatments, participants showed significant improvements across a range of symptoms, including depression, anxiety, and PTSD. “This is the first time we’ve been able to directly modulate deep brain activity without invasive procedures or medications,” said Gregory Fonzo, Ph.D., the study's senior author.</div><div style="text-align: justify;">The treatment, which was well tolerated with no serious adverse events, reduced amygdala activity both immediately and over the course of the treatment period. This offers new hope for patients who haven’t responded to traditional therapies. Researchers are optimistic about the safety and efficacy of this non-invasive approach and are planning larger clinical trials.</div><div style="text-align: justify;">References: Barksdale, B. R., et al. (2025). Low-intensity transcranial focused ultrasound amygdala neuromodulation: a double-blind sham-controlled target engagement study and unblinded single-arm clinical trial. Molecular Psychiatry. doi.org/10.1038/s41380-025-03033-w.</div></div>

345. USFDA approves AbbVie giant cell arteritis drug Rinvoq in adults

     Wed, 30 Apr 2025 11:00:25 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/24/232984-abbvie-50.webp' /><p><b style="text-align: justify;">North Chicago, Ill.:</b><span style="text-align: justify;">&nbsp;<a href="https://medicaldialogues.in/topics/abbvie">AbbVie </a>has received approval from the U.S. Food and Drug Administration (FDA) for RINVOQ (<a href="https://medicaldialogues.in/topics/upadacitinib">upadacitinib</a>), 15 mg, once daily, for the treatment of adults with <a href="https://medicaldialogues.in/topics/giant-cell-arteritis">giant cell arteritis</a> (GCA).</span></p><p style="text-align: justify; ">This comes after the European Commission recently granted marketing authorization of RINVOQ for the treatment of GCA in adult patients.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The approvals are supported by results of the pivotal Phase 3 SELECT-GCA clinical trial, which met the primary endpoint of sustained remission (46.4% of patients receiving RINVOQ 15 mg in combination with a 26-week steroid taper regimen achieved sustained remission from week 12 to week 52, compared to 29.0% of patients receiving placebo in combination with a 52-week steroid taper regimen; p=0.002).</p><p style="text-align: justify; ">During the 52-week, placebo-controlled period, the safety profile of RINVOQ was generally consistent with that observed in other approved indications.</p><p style="text-align: justify; ">"This FDA approval will now provide an alternative treatment option that can offer patients with GCA the possibility of tapering off steroids and achieving sustained remission," said Roopal Thakkar, M.D., executive vice president, research and development, chief scientific officer, AbbVie. "With this new indication for RINVOQ, we are underscoring AbbVie's commitment to exploring how we can identify and address unmet needs for patients with immune-mediated diseases."</p><p style="text-align: justify; ">GCA is an autoimmune disease that causes inflammation of the temporal and other cranial arteries, the aorta, and other large and medium arteries. If left untreated, the disease can lead to debilitating symptoms and potentially severe outcomes, such as blindness, aortic aneurysm, or stroke. Caucasian women over the age of 50 – most commonly between the ages of 70 and 80 years – have the highest risk of developing GCA. Although women are more likely than men to develop GCA, research suggests that men are more likely to have ocular manifestations with their disease.</p><p style="text-align: justify; ">"Glucocorticoids remain a mainstay of treatment of GCA but lead to substantial drug-associated toxicities. Additionally, relapse remains common for patients with this disease," said Peter A. Merkel, M.D., MPH, chief of rheumatology at the University of Pennsylvania, Philadelphia, and SELECT-GCA trial investigator. "We now have a new option to treat GCA. The results of this clinical trial show that upadacitinib offers patients the chance to reach sustained remission."</p></div>

346. NEET 2025: Aadhaar Verification Confusion Sparks Panic Days Before Exam

     Wed, 30 Apr 2025 10:46:17 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285022-aadhar-verification.webp' /><p style="text-align: justify; "><b>New Delhi- </b>In less than a week, the National Testing Agency (NTA) is going to conduct the National Eligibility and Entrance Test-Undergraduate (NEET UG) medical entrance exam for the academic year 2025. Meanwhile, confusion and anxiety have erupted among the candidates as they have been asked to provide their Aadhaar details for verification, despite that NTA had earlier allowed candidates to use identification methods other than Aadhaar for NEET registration.</p><p style="text-align: justify; ">It is reported that many candidates who opted for them said they received a message on Tuesday asking them to switch to Aadhaar-based authentication. Now, when they are trying to do so, the candidates are unable to go through the verification process despite multiple attempts.</p><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-nta-notifies-advance-intimation-of-exam-city-for-candidates-147214"><b>Also Read:&nbsp;</b>NEET 2025: NTA notifies Advance Intimation of Exam City for candidates</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">According to a NewsCareer360 report, The text message asked candidates to check their emails for a link to update the authentication mode in Aadhaar by 11:50 pm today, i.e. Wednesday, April 30. Candidates visited the NTA website to complete the formality, however, they received a message that read, "Your Aadhaar authentication form has not been submitted. Please try again".</p><p dir="ltr" style="text-align: justify; ">The NTA decided to go for Aadhaar verification after widespread reports of irregularities, including paper leaks and security breaches during the NEET last year. Hence, in January, the NTA had issued a notice urging candidates to use their Automated Permanent Academic Account Registry (APAAR) ID, a newly introduced Aadhaar-linked digital record of academic achievements and Aadhaar-based authentication, to register for NEET UG 2025. However, the agency later clarified that APAAR integration is not mandatory.</p><p dir="ltr" style="text-align: justify; ">Students were given three methods of verification in the NEET 2025 application form – Aadhaar, APAAR and any other ID.</p><p dir="ltr" style="text-align: justify; ">On this, speaking to NewsCareer360, a candidate from Mumbai said, “I called NTA twice to inform them about the issue. They told us that the process is stuck due to heavy traffic on the portal. I was asked to share the screenshot of the failure message via email, which I did, but to no avail.”</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-on-may-4-check-out-city-intimation-admit-card-result-dates-146244"><b>Also Read:&nbsp;</b>NEET 2025 on May 4: Check Out City Intimation, Admit card, Result Dates</a></div><div class="pasted-from-word-wrapper"><div></div></div>

347. NBE Releases Final Mop-up Round Schedule for Sponsored Post MBBS DNB Counselling, Check Seat Matrix, Eligibility Lists

     Wed, 30 Apr 2025 10:30:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285012-schedule.webp' /><p style="text-align: justify; "><b>New Delhi- </b>Through a notice, the National Board of Examinations in Medical Sciences (NBEMS) has released the schedule for the Final (Mop-up) Round of Online Centralised Merit-Based Counselling for Sponsored Post MBBS DNB seats of the 2024 admission Session.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">As per the notice, the schedule of the Final (Mop-up) Round of the online Centralised Merit-Based counselling for the 2024 Admission Session will commence from 5th May, 2025, till 19th May, 2025. </p><p dir="ltr" style="text-align: justify; "><b><i>Below is the complete schedule-</i></b></p></div><div class="pasted-from-word-wrapper" style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/nbe-invites-applications-for-diploma-final-exams-june-2025-details-147495"><b>Also Read:&nbsp;</b>NBE Invites Applications for Diploma Final Exams June 2025, details</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u>SCHEDULE</u></b></p><div dir="ltr"><table style="text-align: justify; "><colgroup><col width="54"><col width="362"><col width="208"></colgroup><tbody><tr><td><p dir="ltr" style="text-align: center; "><b>S.NO</b></p></td><td><p dir="ltr" style="text-align: center; "><b>COUNSELING PROCESS </b></p></td><td><p dir="ltr" style="text-align: center; "><b>PERIOD</b></p></td></tr><tr><td><p dir="ltr">1</p></td><td><p dir="ltr">Login by the candidates and Payment of the 1st Year Course Fee to participate in the Final Mop-up Round.</p></td><td><p dir="ltr">5th- 7th May, 2025 (till 05:00 PM)</p></td></tr><tr><td><p dir="ltr">2</p></td><td><p dir="ltr">Filling of Choices/ options for the Final (Mop-up) Round of Counselling.</p></td><td><p dir="ltr">5th- 7th May, 2025 (till 05:00 PM)</p></td></tr><tr><td><p dir="ltr">3</p></td><td><p dir="ltr">Processing of the Allotment.</p></td><td><p dir="ltr">8th May, 2025</p></td></tr><tr><td><p dir="ltr">4</p></td><td><p dir="ltr">Result of the Allotment.</p></td><td><p dir="ltr">9th May, 2025</p></td></tr><tr><td><p dir="ltr">5</p></td><td><p dir="ltr">Physical joining at the allotted Institute.</p></td><td><p dir="ltr">9th-19th May, 2025</p></td></tr></tbody></table></div><p dir="ltr" style="text-align: justify; ">Candidates who fail to join their allotted institution in the Final (Mop-up) Round of counselling by the stipulated date, i.e. 19 May 2025, will lose their Sponsored Post MBBS DNB Seat &amp; their First Year Course Fee shall be forfeited.</p><p dir="ltr" style="text-align: justify; ">For the Final (Mop-up) Round of the online Centralised Merit-Based counselling for the 2024 admission, only those candidates who are already registered for the counseling and have not been allotted any seat during the First and/ or Second round of the Counseling, will be eligible to participate in the Final (Mop-up) Round of counseling.</p><p dir="ltr" style="text-align: justify; "><b><i>Although candidates who have been allotted a seat in any of the previous rounds of the counselling, but-</i></b></p><p dir="ltr" style="text-align: justify; ">1 have opted not to freeze the same.</p><p dir="ltr" style="text-align: justify; ">2 have not paid the First Year Course Fee after freezing the seat.</p><p dir="ltr" style="text-align: justify; ">3 After payment of the First Year Course fee fails to join the institute allotted.</p><p dir="ltr" style="text-align: justify; ">4 After payment of the First Year Course fee fails to produce his/her original documents for verification by the institute.</p><p dir="ltr" style="text-align: justify; ">5 After payment of the First Year Course fee fails to fulfil the eligibility criteria prescribed during the verification of documents.</p><p dir="ltr" style="text-align: justify; ">shall also not be eligible for participation in the mop-up round of counselling.</p><p dir="ltr" style="text-align: justify; ">The notice further stated that the candidates who have been declared qualified after the reduction of the minimum qualifying percentile were allowed to submit their NOC till 25th April, 2025, for participation in the Final (Mop-up) Round of the Counselling. </p><p dir="ltr" style="text-align: justify; ">Meanwhile, eligible candidates shall be allowed to participate in the Final (Mop-up) Round of Sponsored Post MBBS DNB seat Counselling for the 2024 admission session. However, the newly eligible candidates shall be informed by NBEMS accordingly regarding Registration for the counselling.</p><p dir="ltr" style="text-align: justify; "><b><u><i>To view the notice, click the link below</i></u></b></p><p dir="ltr" style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/nbe-releases-schedule-for-final-mop-up-round-of-2024-sponsored-post-mbbs-dnb-counsellingjpg-285014.pdf">https://medicaldialogues.in/pdf_upload/nbe-releases-schedule-for-final-mop-up-round-of-2024-sponsored-post-mbbs-dnb-counsellingjpg-285014.pdf</a><a href="https://medicaldialogues.in/pdf_upload/nbe-releases-schedule-for-final-mop-up-round-of-2024-sponsored-post-mbbs-dnb-counsellingjpg-285014.pdf" target="_blank"></a></p></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u>SEAT MATRIX</u></b></p><p dir="ltr" style="text-align: justify; ">Along with this, NBEMS has also released the indicative seat matrix for the Final (Mop-up) Round of Counselling for admission to Sponsored Post MBBS DNB courses 2024 Admission Session. As per the seat matrix, a total of 29 seats are vacant across 8 Post MBBS DNB courses across hospitals/institutions of India. </p><p dir="ltr" style="text-align: justify; ">The indicative seat matrix has been released in a PDF format on the official website of NBEMS, therefore, candidates can view and download the same from there. The seat matrix contains important details such as Name of Hospital/Institution, State, Speciality and Total No. of Seats. Below are the details</p><div dir="ltr"><table style="text-align: justify; "><colgroup><col width="55"><col width="213"><col width="356"></colgroup><tbody><tr><td><p dir="ltr" style="text-align: center; "><b>S.NO</b></p></td><td><p dir="ltr" style="text-align: center; "><b>SPECIALITY</b></p></td><td><p dir="ltr" style="text-align: center; "><b>TOTAL NO. OF SEATS</b></p></td></tr><tr><td><p dir="ltr">1</p></td><td><p dir="ltr">Anaesthesiology.</p></td><td><p dir="ltr">6</p></td></tr><tr><td><p dir="ltr">2</p></td><td><p dir="ltr">Community Medicine.</p></td><td><p dir="ltr">1</p></td></tr><tr><td><p dir="ltr">3</p></td><td><p dir="ltr">Family Medicine.</p></td><td><p dir="ltr">4</p></td></tr><tr><td><p dir="ltr">4</p></td><td><p dir="ltr">General Surgery.</p></td><td><p dir="ltr">12</p></td></tr><tr><td><p dir="ltr">5</p></td><td><p dir="ltr">Microbiology.</p></td><td><p dir="ltr">1</p></td></tr><tr><td><p dir="ltr">6</p></td><td><p dir="ltr">Obstetrics and Gynaecology.</p></td><td><p dir="ltr">2</p></td></tr><tr><td><p dir="ltr">7</p></td><td><p dir="ltr">Ophthalmology.</p></td><td><p dir="ltr">2</p></td></tr><tr><td><p dir="ltr">8</p></td><td><p dir="ltr">Radio Diagnosis.</p></td><td><p dir="ltr">1</p></td></tr><tr><td></td><td><p dir="ltr" style="text-align: center; "><b>TOTAL</b></p></td><td><p dir="ltr" style="text-align: center; "><b>29</b></p></td></tr></tbody></table></div><p dir="ltr" style="text-align: justify; "><b><u><i>To view the seat matrix, click the link below</i></u></b></p><p dir="ltr" style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/seat-matrixjpg-285038.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/seat-matrixjpg-285038.pdf</a></p></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u>ELIGIBLE AND NOT-ELIGIBLE LISTS</u></b></p><p dir="ltr" style="text-align: justify; ">Moreover, NBEMS has released the Provisional List of Candidates Eligible and Not Eligible</p><p dir="ltr" style="text-align: justify; ">for participation in the Final (Mop-up) Round of Sponsored Post MBBS DNB Seats Counselling for 2024 Admission Session. As per the list, a total of 190 candidates are provisionally eligible and only 1 candidate is considered not-eligible. </p><p dir="ltr" style="text-align: justify; ">The list has been released in a PDF format on the official website of NBEMS, therefore, candidates can view and download the same from there. The list contains important details such as roll number, rank, eligibility and remarks. </p><p dir="ltr" style="text-align: justify; "><b><u><i>To view both the lists, click the link below</i></u></b></p><p dir="ltr" style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/not-eligible-listsjpg-285039.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/not-eligible-listsjpg-285039.pdf</a></p></div><div class="pasted-from-word-wrapper"><a href="https://medicaldialogues.in/pdf_upload/eligible-listsjpg-285040.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/eligible-listsjpg-285040.pdf</a></div><div class="pasted-from-word-wrapper"><div></div></div><div class="pasted-from-word-wrapper"></div><div class="pasted-from-word-wrapper"><div></div></div>

348. JnK HC grants bail in NDPS case for medical emergency

     Wed, 30 Apr 2025 10:15:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/08/273340-probe-ordered-1.webp' /><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Srinagar: The </span><span style="background-color: rgb(255, 255, 255);">Jammu and Kashmir and Ladakh High Court has granted bail to a petitioner, observing that it is essential for an&nbsp;</span>elder male member of a family to be present when attending to an&nbsp;<span style="background-color: rgb(255, 255, 255);">ailing daughter who requires surgery or hospitalisation.</span></p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The petitioner was arrested under sections 8/15 and 29 of the <a href="https://medicaldialogues.in/topics/Narcotic-Drugs-and-Psychotropic-Substances" target="_blank">Narcotic Drugs and Psychotropic Substances</a> (NDPS) Act, 1985. The petitioner came to apply for a grant of bail on the contingency of the ailment of his school-going minor daughter for the purpose of getting her medically examined, which required ENT surgery.</p></div><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><a class="also-read-media-wrap" href="https://medicaldialogues.in/news/health/doctors/gmc-jammu-medical-superintendent-removed-over-controversial-circular-on-pahalgam-attack-147451"><img class="also-read-media" data-src="https://medicaldialogues.in/h-upload/2022/07/04/179940-transfer-1.webp"></a><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/gmc-jammu-medical-superintendent-removed-over-controversial-circular-on-pahalgam-attack-147451"><b><u><span class="read-this-also">Also Read:</span>GMC Jammu Medical Superintendent removed over circular on Pahalgam attack</u></b></a><div></div></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The court of Principal Sessions Judge, Kulgam was granted a short-term bail when the petitioner came to be enlarged on bail for a period up-till 15th of April, 2025 from the date of passing of order dated 29.03.2025 with a condition for the petitioner to surrender before the Superintendent District Jail, Kuthua on 15.04.2025 before 4.00 P.M. On the basis of the short-term bail so granted, the petitioner was able to get her school-going minor daughter medically examined in Sher-e-Kashmir Institute of Medical Sciences, Soura, Srinagar, as an OPD patient.</p> <p style="text-align: justify; ">The petitioner’s daughter has been diagnosed with an ailment known as Submucosal Nasal Twang. As per the OPD prescription, a date for surgery of the petitioner’s daughter was given for the 23rd of April, 2025. But as his previous bail failed on 15^th April, he rushed to the court with another bail application. However, the Court of Principal Sessions Judge, Kulgam, refused to extend the bail. The petitioner then approached this Court with a bail petition seeking bail relatable to the medical treatment of his daughter.</p> <p style="text-align: justify; ">After considering the submission the court observed, “ This bail petition can be disposed of at this stage as the reasoning given by the learned Principal Sessions Judge, Kulgam may have some factual basis to be cited so but nevertheless given the fact that for her minor daughter the petitioner is the only guardian who is supposed to attend her ailment, as such, the Principal Sessions Judge, Kulgam ought to have continued with the judicial trust in the petitioner with respect to the contingency of attending upon her daughter advised medical surgery for 23rd of April, 2025.”</p></div><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><a class="also-read-media-wrap" href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471"><img class="also-read-media" data-src="https://medicaldialogues.in/h-upload/2024/02/01/231362-orissa-high-court.webp"></a><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/criminal-cases-cannot-be-lodged-against-doctors-because-they-prescribed-costlier-drugs-hc-147471"><b><u><span class="read-this-also">Also Read:</span>Criminal cases cannot be lodged against Doctors because they prescribed costlier drugs: HC</u></b></a><div></div></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The court also considered that it may be the petitioner’s counsel who had moved the petition for seeking short-term bail from the Court of Principal Sessions Judge, Kulgam, was not able to stitch facts properly, for which the petitioner should not have been made to suffer prejudice of having the denial of extension of bail. The bench granted extension of bail to the petitioner stating, “This Court cannot loose site of the fact that presence of an elder male member of a family for attending upon an ailing daughter requiring surgery/hospitalization is a call of the day keeping in view the nature of the Civil and Social of which all of us are part of.”</p><p style="text-align: justify; "><i><b>To view the official order, click on the link below:</b></i></p></div><div class="hocal-draggable" draggable="true"><b><a href="https://medicaldialogues.in/pdf_upload/aasifaminthokervsjkut-284996.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/aasifaminthokervsjkut-284996.pdf</a></b></div>

349. Strides Pharma buys four approved ANDAs from Nostrum Labs for over Rs 17 crore

     Wed, 30 Apr 2025 09:58:32 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/01/25/230947-acquisition-50-1.webp' /><p><b>Bengaluru</b>:&nbsp;<span style="text-align: justify; background-color: rgb(255, 255, 255);">Strides Pharma Inc., a Step-down wholly-owned subsidiary of</span><span style="text-align: justify;">&nbsp;<a href="https://medicaldialogues.in/topics/strides-pharma-science">Strides Pharma Science Limited</a></span><span style="text-align: justify; background-color: rgb(255, 255, 255);">&nbsp;in the US, has acquired four approved&nbsp;</span><span style="text-align: justify;">Abbreviated New Drug Applications (</span><span style="text-align: justify; background-color: rgb(255, 255, 255);">ANDAs) from Nostrum Laboratories, Inc., USA., for more than Rs</span><span style="text-align: justify;">&nbsp;17 crore&nbsp;</span><span style="text-align: justify;">for the US Market.</span></p><div class="pasted-from-word-wrapper" style="text-align: justify; ">The portfolio consists of liquids and immediate release solid orals which are in the therapeutic segment to treat infections associated with UTIs (Urinary Tract Infections), Pain Management, Allergy Symptoms and Attention Deficit Disorder (ADD/ ADHD) and Narcolepsy. </div><div class="pasted-from-word-wrapper" style="text-align: justify; ">The cumulative market size for the acquired portfolio is ~USD 57 million, as per IQVIA data of 2025. </div><div class="pasted-from-word-wrapper" style="text-align: justify; ">Total consideration for acquisition of the said ANDAs is USD 2.075 million (~INR 176 million).</div><div class="pasted-from-word-wrapper" style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/strides-pharma-secures-nclt-approval-for-onesource-indias-first-specialty-pharma-cdmo-138447" style="background-color: rgb(255, 255, 255);">Strides Pharma Secures NCLT Approval for OneSource, India's First Specialty Pharma CDMO</a></i></b></div><div class="pasted-from-word-wrapper" style="text-align: justify; ">"Two (out of the Four) ANDAs acquired are commercial products and is expected to be launched within 12 months. With access to these products, Strides will expand its portfolio of niche and difficult to manufacture products," the Company stated in a BSE filing.</div><div class="pasted-from-word-wrapper" style="text-align: justify; ">Medical Dialogues team had earlier reported that&nbsp;<span style="background-color: rgb(249, 249, 249);">Strides Pharma Global Pte. Limited (SPG), a step-down wholly-owned Subsidiary of the company in Singapore, had also entered into a Share Purchase Agreement to acquire 100 percent stake in Amexel for a nominal consideration of USD 10.</span></div><div class="pasted-from-word-wrapper"> </div><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/strides-pharma-science-singapore-arm-to-acquire-100-percent-stake-in-amexel-145012">Strides Pharma Science Singapore arm to acquire 100 percent stake in Amexel</a></i></b></p><div class="pasted-from-word-wrapper"><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><p style="text-align: justify; ">Strides, a global pharmaceutical company headquartered in Bengaluru, India, is listed on the BSE Limited (532531) and National Stock Exchange of India Limited (STAR). The Company mainly operates in the regulated markets and has an “in Africa for Africa” strategy and an institutional business to service donorfunded markets. The Company’s global manufacturing sites are located in India (Chennai, Puducherry, and two locations in Bengaluru), Italy (Milan), Kenya (Nairobi), and the United States (New York). The Company focuses on “difficult to manufacture” products sold in over 100 countries. </p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/strides-pharma-science-arm-gets-usfda-nod-for-acetaminophen-and-ibuprofen-tablets-141840">Strides Pharma Science arm gets USFDA nod for Acetaminophen and Ibuprofen Tablets</a></i></b></p></div>

350. 24 Nagpur Hospitals found denying AB-PMJAY Treatment: RTI

     Wed, 30 Apr 2025 09:30:45 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/09/20/220278-suspended.webp' /><p style="text-align: justify; "><b>Nagpur:</b> The Maharashtra Health Department has taken disciplinary action against 24 hospitals in Nagpur district for allegedly denying free treatment to patients under the&nbsp;<a href="https://medicaldialogues.in/topics/ayushman-bharat-pradhan-mantri-jan-arogya-yojana" target="_blank">Ayushman Bharat- Pradhan Mantri Jan Arogya Yojana</a><span style="background-color: rgb(255, 255, 255);"> (AB-PMJAY) scheme.&nbsp;</span>This was revealed in recent data obtained through a Right To Information (RTI) application.</p><p style="text-align: justify; ">In the notices issued to the hospitals, the government has suspended some hospitals, while others have been de-empanelled from the scheme, effectively ending their association with it altogether.</p><p style="text-align: justify; ">The data revealed that between July 2, 2012, and April 24, 2025, nearly 90 cases of treatment denial were recorded, with 87 involving private hospitals and just three linked to government-run facilities.&nbsp;</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/hospital-diagnostics/gujarat-tops-the-list-as-609-private-hospitals-exit-ayushman-bharat-scheme-145830" target="_blank">Gujarat tops the list as 609 private hospitals exit Ayushman Bharat scheme</a></b></p><p style="text-align: justify; ">The State Health Assurance Society shared the data in response to an RTI filed by social activist Sanjay Agrawal, who had sought information on the number of hospitals that offered free treatment under the scheme.&nbsp;</p><p style="text-align: justify; ">Shockingly, the response pointed to major administrative lapses and a significant gap in healthcare delivery, putting at risk the lives of underprivileged patients who depend on the scheme for timely and essential treatment.</p><p style="text-align: justify; ">Among the institutions that turned away patients are Archangel Hospital, Asha Hospital, Cancer Treatment Services (Hyderabad Pvt. Ltd.), City Hospital, Columbia Hospital and Research Center, Gilurkar Multispeciality Hospital and Research Center, Government Medical College and Super Specialty Hospital in Nagpur, Government Medical College Hospital, Kimaya Multispeciality Hospital, Lata Mangeshkar Hospital, Lifeline Multispeciality Hospital (Maternity, ICU &amp; Trauma Center), Mayo Hospital and Research Institute in Butibori, Medicare Multispeciality Hospital, National Cancer Institute, Rashtrasant Tukdoji Regional Cancer Hospital and Research Center, Morge Children’s Hospital, Shri Bhavani Multispeciality Hospital and Research Institute, Shri Krishna Heart and ICU Center, Nimbunabai Tirpude Hospital, Suretech Hospital and Research Center Ltd. (including its Polytrauma, Cardiology &amp; Super-specialty wing), and Swami Vivekanand Medical Mission’s Arogya Seva Kendra at Khapri-Parsodi.</p><p style="text-align: justify; ">Apart from these, private hospitals claimed that Rs 103.19 crore remains unpaid by the government. <a href="https://www.nagpurtoday.in/major-lapse-in-ayushman-bharat-scheme-in-nagpur-24-hospitals-denied-treatment-reveals-rti/04291359" target="_blank" rel="nofollow">Nagpur Today</a> sources indicate that these outstanding dues have discouraged hospitals from providing free treatment.</p><p style="text-align: justify; ">Between April 1, 2024, and April 14, 2025, 19,638 patients in Nagpur district benefited from the Ayushman Bharat scheme, with the majority availing treatment from private hospitals. While the scheme has helped thousands, the denial of services by several hospitals raises concerns about implementation integrity and inclusivity.</p><p style="text-align: justify; ">Ayushman Bharat - Pradhan Mantri Jan Arogya Yojana (AB-PMJAY) is a flagship scheme of the Government that provides health cover of Rs. 5 lakhs per family per year for secondary and tertiary care hospitalisation to approximately 55 crore beneficiaries corresponding to 12.37 crore families, constitutingthe the economically vulnerable bottom 40% of India’s population.</p><p style="text-align: justify; ">Recently, the scheme has been expanded to cover 6 crore senior citizens of age 70 years and above belonging to 4.5 crore families irrespective of their socio-economic status under ABPMJAY with Vay Vandana Card.</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/hospital-diagnostics/899-crore-hospital-admissions-worth-rs-126-lakh-crore-authorised-under-pmjay-145772" target="_blank">8.99 crore hospital admissions worth Rs 1.26 lakh crore authorised under PMJAY</a></b></p>

351. USFDA issues EIR for Alembic Pharma Panelav facility

     Wed, 30 Apr 2025 09:16:54 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/03/231491-usfda-50-1.webp' /><p style="text-align: justify; "><b>Vadodara:&nbsp;</b><a href="https://medicaldialogues.in/topics/alembic-pharma">Alembic Pharma</a>,&nbsp;an Indian multinational pharmaceutical company, has announced that<span style="background-color: rgb(255, 255, 255);">&nbsp;the Company has received an Establishment Inspection Report (EIR) from the US Food and Drug Administration (US FDA) for its Oncology Formulation Facility (Injectable and Oral Solid) (F-2) at Panelav.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">The inspection was held from 7th October, 2024 to 8th October, 2024.&nbsp;</span></p><p style="text-align: justify; "><i style="background-color: rgb(255, 255, 255);"><b>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/alembic-pharma-successfully-completes-usfda-inspection-at-panelav-oncology-formulation-facility-136174">Alembic Pharma successfully completes USFDA inspection at Panelav Oncology formulation facility</a></b></i></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">"We are pleased to inform the exchanges that the Company has received an Establishment Inspection Report (EIR) from the US Food and Drug Administration (US FDA) for the inspection carried out by them at our Oncology Formulation Facility Injectable and Oral Solid) (F-2) at Panelav from 7th October, 2024 to 8th October, 2024," the Company stated in a recent BSE filing.&nbsp;</span></p><p style="text-align: justify; ">The company recently also commissioned a new manufacturing facility in Madhya Pradesh for the production of formulations, representing an investment of approximately Rs 205 crore. According to the company, the rationale behind establishing the facility is to expand its business and provide an opportunity to move third-party products in-house.&nbsp;</p><p>Alembic already operates multiple manufacturing facilities for formulations, most of which are currently operating at optimal utilization levels.</p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/alembic-pharma-commissions-new-manufacturing-facility-in-pithampur-to-expand-business-147402">Alembic Pharma commissions new manufacturing facility in Pithampur to expand business</a></i></b></p><div class="pasted-from-word-wrapper"><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><p style="text-align: justify; ">Alembic Pharmaceuticals Limited, a vertically integrated research and development pharmaceutical company, has been at the forefront of healthcare since 1907. Headquartered in India, Alembic is a publicly listed company that manufactures and markets generic pharmaceutical products all over the world. Alembic's state of the art research and manufacturing facilities are approved by regulatory authorities of many developed countries including the USFDA.</p><p style="text-align: justify; ">Alembic's brands, marketed through a field force of over 5200 are well recognized by doctors and patients. </p><p style="text-align: justify; "><i><b>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/alembic-pharma-appoints-prag-goel-as-vice-president-sales-and-marketing-megacare-enteron-and-osteofit-business-divisions-140817">Alembic Pharma appoints Prag Goel as Vice President - Sales and Marketing (Megacare, Enteron and Osteofit business divisions)</a></b></i></p></div>

352. NEET Tragedy in Kota: 16-year-old Aspirant Dies by Suicide Just 20 Days After Joining Coaching

     Wed, 30 Apr 2025 09:09:27 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/14/282985-suicide-1.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Kota:&nbsp;</span><span style="background-color: rgb(255, 255, 255);">In yet another tragic incident from the country’s coaching hub&nbsp;</span>Kota<span style="background-color: rgb(255, 255, 255);">, a 16-year-old NEET aspirant from Bihar was found dead in his hostel room, just 20 days after joining a coaching centre in the city.</span></p><p><span style="background-color: rgb(255, 255, 255);">This marks the 13th suspected suicide by a coaching student in Kota this year, highlighting the ongoing mental health crisis among competitive exam aspirants.</span></p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Speaking to PTI about the incident, the police informed, "<span style="text-align: justify;">A 16-year-old medical aspirant hanged himself from a ceiling fan in his hostel room in Kota, just 20 days after joining a coaching centre here to prepare for </span><a href="https://medicaldialogues.in/topics/neet" target="_blank" style="background-color: rgb(249, 249, 249); text-align: justify;">NEET</a>."&nbsp;</p><p style="text-align: justify;">A native of Bihar's Katihar, Tameem Iqbal was found hanging from a ceiling fan in his hostel room in Talwandi area on Monday evening, the police stated.</p><p style="text-align: justify;">No suicide note was recovered from the room and the reason behind the extreme step by the boy is yet to be ascertained, Jawahar Nagar Circle Inspector Ramlaxman said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/not-ready-for-neet-2025-delhi-aspirant-found-dead-in-kota-wanted-1-more-year-to-prepare-147309"><b>Also Read:Not ready for NEET 2025, Delhi aspirant found dead in Kota wanted 1 more year to prepare</b></a></p><p style="text-align: justify;">He added that the hostel caretaker informed police after the boy did not open the door on Monday night, despite repeated knocking.</p><p style="text-align: justify;">The police team broke open the door and found the minor boy hanging from the ceiling fan, he said.</p><p style="text-align: justify;">Initial inquiry revealed Iqbal was a class 11 student and came to Kota just 20 days ago. He also enrolled in a coaching institute to prepare for <a href="https://medicaldialogues.in/topics/neet" target="_blank">NEET</a>, the officer added.</p><p style="text-align: justify;">The boy's uncle, who lives in Delhi, reached Kota on Tuesday morning after learning about the tragic incident and the body was handed over to him after the post-mortem, he said, adding that further probe is underway.</p><p style="text-align: justify;">Seventeen coaching students died by <a href="https://medicaldialogues.in/topics/suicide" target="_blank">suicide </a>in Kota in 2024. In 2023, the number stood at 26.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/state-news/rajasthan/neet-aspirant-found-dead-in-kota-suicide-by-poison-suspected-147248"><b>Also Read:NEET Aspirant Found Dead in Kota, Suicide by Poison suspected</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

353. Medicos on Duty, But No Pay: PMO directs Health Ministry to address non-payment of stipend

     Wed, 30 Apr 2025 08:46:06 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/28/284711-stipend.webp' /><p style="text-align: justify; "><b>New Delhi:</b>&nbsp;In the latest development regarding the issue of <a href="https://medicaldialogues.in/topics/non-payment-of-stipend">non-payment of stipend</a> to resident doctors and MBBS interns, the Prime Minister's Office (PMO) has asked the Department of Health and Family Welfare to address the matter and take appropriate action.</p><p style="text-align: justify; ">A recent Right to Information (RTI) application filed by Dr KV Babu, a health activist based in Kerala, revealed that the PMO received Dr. Babu's letter on March 21 and forwarded the same "for action as appropriate" through the Public Grievances Redress and Monitoring System (CPGRAMS) to the <a href="https://medicaldialogues.in/topics/ministry-health-and-family-welfare">Department of Health and Family Welfare</a>, TNIE has reported.</p><p style="text-align: justify; "><i>"Redressal of grievance is under the purview of appropriate authority dealing with subject-specific. Therefore, the information sought relates to the authority concerned to which the complaint was forwarded,"</i> PMO's RTI reply dated April 24, 2025, stated.</p><p style="text-align: justify; ">The PMO's directive comes after an RTI application was filed by Dr. Babu, who has been pursuing the matter concerning the stipend of medical students for the past two years.</p><p style="text-align: justify; ">Medical Dialogues had earlier reported that the file notings of the&nbsp;<a href="https://medicaldialogues.in/topics/nmc">National Medical Commission</a> (NMC), obtained through a <a href="https://medicaldialogues.in/topics/right-to-information-act">Right to Information</a> (RTI) application, revealed that altogether 33 Government and 27 private medical colleges were not paying any stipends to their MBBS interns, postgraduate resident doctors, and senior doctors.&nbsp;</p><p style="text-align: justify; ">NMC revealed this data after the doctor sought copies of the legal opinion availed by NMC regarding action against medical colleges based on the show cause notice dated 28.11.2024 issued to 198 medical colleges. He had also sought the file noting along with the copies of affidavits filed in the Supreme Court this year.</p><p style="text-align: justify; ">Last year in November, NMC had slapped&nbsp;<a href="https://medicaldialogues.in/topics/show-cause-notice">show-cause notices</a> on 198 medical institutes for not complying with the Commission's directives to uphold the details of the stipend paid to the interns and resident doctors. Releasing a list of these medical colleges on 28.11.2024, NMC specified that the failure of those colleges to submit the information regarding stipends was "considered seriously". NMC asked the medical colleges to furnish the data after the Supreme Court took cognisance of the issue of non payment of stipend to medical colleges.</p><p style="text-align: justify; ">However, the file noting dated 11.07.2024 revealed that only 290 government and 265 private medical colleges, including Deemed to be Universities, furnished their data for 2023-2024 till 11.07.2024. The remaining 198 colleges (115 government and 83 private colleges), including Deemed to be Universities out of a total of 753 colleges, did not furnish their data.</p><div class="pasted-from-word-wrapper"><div class="inside-post-ad-2 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_2"></div><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/health-news/nmc/action-against-198-medical-colleges-over-non-payment-of-stipend-for-medicos-nmc-says-matter-sub-judice-142205"><i><b>Also Read: Action Against 198 medical colleges over non-payment of Stipend for Medicos? NMC says Matter sub-judice</b></i></a></p><p style="text-align: justify; ">Even though the note hinted at the possibility of action being taken against defaulting medical colleges, and the NMC had mentioned issuing show-cause notices to colleges, no action was taken. </p><p style="text-align: justify; ">When Dr. Babu filed another RTI seeking the details of action taken by the Boards/NMC against medical colleges for non-compliance under Maintenance of Standards of Medical Education Regulations, 2023, along with the details of action taken for irregularities in the payment of stipends to interns/PGs during this period, NMC clarified that the States/UTs had the responsibility to take action, not NMC.</p><p style="text-align: justify; ">Back on January 29, the doctor had also written to the Union Health Minister J P Nadda urging him to intervene under Section 45 of the NMC Act, which empowers the Central Government to issue policy directions to the Commission and Autonomous Boards.</p><p style="text-align: justify; ">Since NMC did not take any action against the defaulting colleges and the Health Ministry failed to ensure that the Council followed the rules, he then wrote to the PMO on March 16 and raised the issue. When he did not receive any response, he filed an RTI on march 23 seeking to know the status of his letter to the PMO.</p><p style="text-align: justify; ">Commenting on this, he told <a href="https://www.newindianexpress.com/nation/2025/Apr/29/pmo-directs-union-health-ministry-to-address-non-payment-of-stipends-to-medical-college-interns-residents" rel="nofollow">The New Indian Express</a>, "Here is a peculiar situation, and hence, I have made the request to the PMO. The State Medical Councils have no jurisdiction on this issue, and the NMC has failed to take action, while the Health Ministry has been evasive, though payment of stipend to MBBS interns and PG doctors is mandatory. Non-payment of stipend is punishable, as per the NMC regulations."</p><p style="text-align: justify; ">"I do believe intervention by the PMO will end the injustice to interns and PG doctors who are not being paid any stipend or even nominal stipends by many medical college managements across the nation," he added.</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/60-medical-colleges-not-paying-stipend-to-medicos-nmc-response-to-rti-143862" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: 60 Medical Colleges Not Paying Stipend to Medicos- NMC response to RTI</i></b></a></p></div>

354. Delhi to become model state for AYUSH: Health Minister

     Wed, 30 Apr 2025 08:18:08 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284995-pankaj-singh-1.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">New Delhi: To strengthen traditional healthcare services, the Delhi government will soon deploy a mobile 'medical awareness van' to offer Ayush consultations and services in the slums and JJ clusters, Health Minister <a href="https://medicaldialogues.in/topics/pankaj-kumar-singh" target="_blank">Pankaj Kumar Singh</a> said on Tuesday. &nbsp;</span></p><p style="text-align: justify; ">The move will bring holistic care to the doorsteps of the underserved, he said.</p><p style="text-align: justify;">According to the PTI report, the Delhi government will roll out a series of ambitious initiatives to strengthen Ayush healthcare services in the national capital, including the launch of an integrated stress management programme and a state-of-the-art Ayush wellness centre, Singh said.</p><p style="text-align: justify;">"Delhi will become a model state for <a href="https://medicaldialogues.in/topics/Ayush" target="_blank">Ayush</a>, offering holistic healing and effective treatment for lifestyle disorders, benefiting all citizens," Singh said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/ayushman-vay-vandana-delhi-launches-rs-10-lakh-health-cover-for-senior-citizens-147480"><b>Also Read:Ayushman Vay Vandana: Delhi launches Rs 10 lakh health cover for Senior Citizens</b></a></p><p style="text-align: justify;">The stress management programme will integrate elements from yoga, Unani and homoeopathy to address rising cases of anxiety, depression, and other stress-related conditions, the health minister said.</p><p style="text-align: justify;">Chairing a review meeting with officials from the Directorate of <a href="https://medicaldialogues.in/topics/Ayush" target="_blank">Ayush </a>and various Ayurveda, Unani and homoeopathy institutions, Singh said Delhi aims to become a model state for Ayush-based healthcare, which offers holistic healing and effective treatment for lifestyle disorders.</p><p style="text-align: justify;">As part of the outreach efforts, a mobile medical awareness van will be deployed to provide Ayush consultations and services in the underserved areas, including slums and JJ clusters.</p><p style="text-align: justify;">"This will bring holistic healthcare to the doorsteps of people who might not otherwise have access to it," Singh said, reports PTI.</p><p style="text-align: justify;">The government also plans to implement the National <a href="https://medicaldialogues.in/topics/Ayush" target="_blank">Ayush </a>Mission in Delhi to streamline and expand access to traditional medicine systems.</p><p style="text-align: justify;">Officials said the mission would promote preventive care and holistic healing by integrating Ayush services into the city's broader healthcare network.</p><p style="text-align: justify;">To boost Ayush education, the minister directed officials to begin revamping infrastructure at the Ayush colleges, particularly student hostels.</p><p style="text-align: justify;">He also urged the hospital staff to maintain hygienic conditions and adopt a compassionate approach in patient care.</p><p style="text-align: justify;">&nbsp;"A clean and compassionate environment is fundamental to healing," Singh said.</p><p style="text-align: justify;">The Ayush wellness centre to be set up in Delhi will offer comprehensive treatment and wellness services, furthering the government's aim to provide accessible and affordable traditional healthcare options, he added.</p><p style="text-align: justify;">The health minister also underlined the Delhi government's broader vision to create a healthier and more resilient city by blending traditional systems with modern public health infrastructure.</p><p style="text-align: justify;">Under the leadership of Prime Minister Narendra Modi and Chief Minister Rekha Gupta, the capital is poised to become a leading hub for Ayush-based healthcare in the country, Singh said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/ayushman-bharat-scheme-to-roll-out-in-delhi-today-146363"><b>Also Read:Ayushman Bharat scheme to roll out in Delhi Today</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

355. Fixed duration Calquence based regimens recommended for EMA Committee for chronic lymphocytic leukaemia: AstraZenaca

     Wed, 30 Apr 2025 08:00:46 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/06/17/241275-astrazeneca-50.webp' /><p><a href="https://medicaldialogues.in/topics/AstraZeneca" style="text-align: justify;">AstraZeneca</a><span style="text-align: justify;"> </span><span style="text-align: justify;">has announced that a fixed-duration regimen of </span><span style="text-align: justify;">Calquence</span><span style="text-align: justify;">&nbsp;(</span><a href="https://medicaldialogues.in/topics/acalabrutinib" style="text-align: justify;">acalabrutinib</a><span style="text-align: justify;">)</span><span style="text-align: justify;">&nbsp;</span><span style="text-align: justify;">in combination with venetoclax, with or without obinutuzumab, has been recommended for approval in the European Union (EU) for the treatment of adult patients with previously untreated chronic lymphocytic leukaemia (CLL).</span></p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) based its positive opinion on results from the AMPLIFY Phase III trial, which were presented at the American Society of Haematology (ASH) 2024 Annual Meeting and published in The New England Journal of Medicine.</p><p style="text-align: justify; ">Results showed Calquence plus venetoclax reduced the risk of disease progression or death by 35% compared to standard-of-care chemoimmunotherapy (investigator’s choice of fludarabine-cyclophosphamide-rituximab or bendamustine-rituximab; hazard ratio [HR] 0.65; 95% confidence interval [CI] 0.49-0.87; p=0.0038). Calquence plus venetoclax with obinutuzumab demonstrated a 58% reduction in the risk of disease progression or death compared to standard-of-care chemoimmunotherapy (HR 0.42; 95% CI 0.30-0.59; p&lt;0.0001).</p><p style="text-align: justify; ">At three years, 77% of patients treated with Calquence plus venetoclax and 83% of patients treated with Calquence plus venetoclax and obinutuzumab were progression free, versus 67% of patients treated with chemoimmunotherapy. Median progression-free survival (PFS) was not reached for either experimental arm versus 47.6 months for chemoimmunotherapy.</p><p style="text-align: justify; ">Wojciech Jurczak, MD, Maria Sklodowska-Curie National Institute of Oncology, Kraków, Poland and investigator for the trial, said, “Chronic lymphocytic leukaemia is an incurable cancer which means patients live with the disease and stay on treatment for many years, which can have long-term effects. The fixed-duration Calquence regimens will allow patients to take breaks from their treatment, reducing the risk of long-term adverse events and drug resistance.”</p><p style="text-align: justify; ">Susan Galbraith, Executive Vice President, Oncology Haematology R&amp;D, AstraZeneca, said, “With this recommendation, Calquence plus venetoclax can potentially be the only all-oral second-generation BTK inhibitor option approved in Europe for patients with previously untreated chronic lymphocytic leukaemia. Calquence has demonstrated efficacy and safety in fixed-duration and treat-to-progression regimens providing patients and their doctors more treatment flexibility.”</p><p style="text-align: justify; ">CLL is the most common type of leukaemia in adults, with an estimated 27,000 patients diagnosed in the UK, France, Germany, Spain and Italy in 2024.</p><p style="text-align: justify; ">The safety and tolerability of Calquence was consistent with its known safety profile, and no new safety signals were identified.</p><p style="text-align: justify; ">Regulatory applications for Calquence plus venetoclax, with or without obinutuzumab, in this setting are currently under review in several countries based on the AMPLIFY results.</p></div>

356. 17-year-old girl Dies after injection, Family Alleges Medical Negligence

     Wed, 30 Apr 2025 07:45:06 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/05/20/238727-alleged-medical-negligence.webp' /><p><b>Haveri: </b>In a tragic incident, a 17-year-old girl died after allegedly suffering a severe adverse effects to an injection administered at a <a href="https://medicaldialogues.in/topics/private-hospitals">private hospital</a> in the city. The teenager had visited the hospital to seek treatment for a minor boil on her wrist.&nbsp;</p><p>According to the family, the girl was in good health earlier that day and was advised by the medical staff to undergo a minor surgical procedure. She was administered medication through a saline drip. However, shortly afterwards, she experienced severe complications, including intense itching and foaming in the mouth. Despite immediate attention, she could not be revived.</p><p>The deceased has been identified as a 17-year-old girl from Hedigonda village in Byadagi taluk, who had visited the hospital for treatment of a minor boil on her wrist.</p><p>Following their daughter’s demise on Tuesday, her grief-stricken parents placed her body outside the hospital to demand accountability and justice. They have accused the hospital of medical negligence, pointing out that their daughter had walked in with a minor issue and lost her life within hours. </p><p>After the incident unfolded, the hospital staff, including the attending doctors, were reportedly not present at the facility.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/kamineni-hospitals-found-vicariously-liable-for-medical-negligence-in-patients-death-147245" style="background-color: rgb(255, 255, 255);"><b>Also Read: Kamineni Hospitals found vicariously liable for medical negligence in patient's death</b></a></p><p>Taluk medical officer Dr. Prabhakar Kundur visited the hospital and conducted a preliminary inspection. Speaking to <a href="https://timesofindia.indiatimes.com/city/hubballi/teenage-girl-dies-after-alleged-medical-negligence-at-hosp/articleshow/120738656.cms" rel="nofollow">TOI</a>, he said they collected details and would temporarily close the hospital. He said a detailed report would be forwarded to senior officials for appropriate action.</p><p>Additional Superintendent of Police L.S. Shirakol, along with City CPI Mothilal Pawar and other police personnel, visited the scene to assess the situation and ensure order.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/up-ima-president-3-doctors-booked-for-alleged-negligence-after-patients-death-147072" style="background-color: rgb(255, 255, 255);"><b>Also Read: UP IMA President, 3 doctors booked for alleged negligence after patient's death</b></a></p><p>Medical Dialogues had previously reported that the President of the Uttar Pradesh chapter of the Indian Medical Association (IMA) and three other doctors have been booked in an alleged case of medical negligence following the death of a woman after childbirth at a private nursing home in Shahjahanpur district owned by the IMA president. The family of the deceased created an uproar for several hours at the hospital until the police registered an FIR.</p>

357. FIR against 2 doctors for forging documents to frame colleague as Quack

     Wed, 30 Apr 2025 07:18:43 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/31/280914-doctor-booked.webp' /><p style="text-align: justify; "><b>Chhatrapati Sambhajinagar:</b> In a recent case of forgery, an FIR has been registered against three individuals of a health department for allegedly trying to frame a qualified and authentic government doctor as a fake by forging his degree and other documents.</p><p style="text-align: justify; ">As a result of their actions, the doctor was labelled as a '<a href="https://medicaldialogues.in/topics/fake-doctor" target="_blank">fake doctor</a>'&nbsp;and dismissed from his position. He was also falsely implicated in a molestation case. Police investigation suggests that the conspiracy was driven by a colleague's desire to take over his position.</p><p style="text-align: justify; ">The three individuals booked in the case include a former district health officer, a current taluka health officer, and a Class IV employee. The FIR was registered following directions from the district and sessions court, after the police allegedly failed to act earlier due to alleged political pressure.&nbsp;</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/news/health/doctors/fake-orthopaedic-surgeon-arrested-for-using-forged-degrees-fraudulent-ids-147422" target="_blank"> Fake orthopaedic surgeon arrested for using forged degrees, Fraudulent IDs</a></b></p><p style="text-align: justify; ">The accused men have been booked under IPC sections 465 (punishment for forgery), 467 (forgery of valuable securities), 471 (using as genuine a forged document), 420 (cheating), 201 (destruction of evidence), and 120-B (criminal conspiracy).</p><p style="text-align: justify; ">The case centres around Dr Mohsin Khan, who worked as the taluka health officer in Sillod. In April 2023, he was accused of holding a fake medical degree. Based on the complaint lodged by the then district health officer, he was booked for cheating and forgery and was removed from his service.&nbsp;</p><p style="text-align: justify; ">However, a later police investigation revealed that Dr Khan’s degree was genuine and had been issued by Veer Bahadur Purvanchal University in Uttar Pradesh, not from the bogus Sai Ayurvedic College in Aligarh, as claimed.</p><p style="text-align: justify; ">According to police, the three accused conspired to create and submit forged documents to show Khan’s degree as fake. Based on this, a false FIR was registered, and he was labelled a "fake doctor." <a href="https://timesofindia.indiatimes.com/city/aurangabad/former-district-health-officer-taluka-health-officer-among-3-booked-for-framing-govt-doctor-with-forged-documents-getting-him-fired-from-job/articleshow/120739065.cms" rel="nofollow">TOI </a>sources claimed that the conspiracy may have stemmed from a colleague’s desire to take over Khan’s post.&nbsp;</p><p style="text-align: justify; ">Police told the Daily, "The colleague earlier pressured senior officials for the post and, along with the former DHO, allegedly demanded a bribe from Dr Khan to prevent repeated transfers. When Khan refused to pay, he was threatened and later implicated in a false molestation complaint filed by a female colleague."&nbsp;</p><p style="text-align: justify; ">Dr Khan said he had informed senior officials in writing about the harassment and began collecting proof of his innocence. The turning point came when police found his original degree certificates at the residence of the former district health officer.</p><p style="text-align: justify; ">Despite filing a complaint in September 2024, no action was initially taken, reportedly due to political pressure. It was only after he approached the court that the police were directed to register the FIR.</p><p style="text-align: justify; ">Speaking to TOI, Dr Khan said, "The accused conspired against me to ruin my career because I refused to pay a bribe and attempted to expose their wrongdoings. They filed a false molestation case and declared my degree fake. Today, the law has finally taken its course."</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/news/health/doctors/fake-cardiologist-row-2-top-uk-hospitals-deny-association-147315" target="_blank"> Fake Cardiologist Row: 2 Top UK Hospitals deny Association</a></b></p>

358. New NMC Move: Non-Teaching Doctors from Govt institutes now eligible for Faculty roles

     Wed, 30 Apr 2025 07:16:53 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284989-faculty-shortage.webp' /><p style="text-align: justify; "><b>New Delhi:</b>&nbsp;Non-teaching consultants and specialists working in government hospitals are going to be allowed to work as faculty in medical colleges, the chairman of the National Medical Commission (NMC), Dr BN Gangadhar, has confirmed.</p><p style="text-align: justify; ">NMC took this decision to increase the faculty pool in the medical colleges, and the specialist doctors who will be roped in to work as faculties include the specialists serving in defence and railway medical facilities as well.&nbsp;</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/health-news/nmc/whats-the-new-eligibility-criteria-for-non-teaching-doctors-check-out-nmc-draft-teq-provisions-142026" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: What's the new eligibility criteria for non-teaching doctors? Check out NMC Draft TEQ provisions</i></b></a></p><p style="text-align: justify; ">Confirming this, the NMC Chairman, Dr. Gangadhar, told <a href="https://www.thehindu.com/sci-tech/health/national-medical-commission-allows-specialists-working-in-non-teaching-govt-healthcare-institutes-to-be-faculty-in-medical-colleges/article69504997.ece" rel="nofollow">The Hindu</a> that non-teaching consultants, specialists, and medical officers with postgraduate medical degrees, and with two years of experience in a district headquarters government hospital or a 220-bed government hospital, would be eligible to become an Assistant Professor of that broad speciality.</p><p style="text-align: justify; ">Dr. Gangadhar further added that if they had 10 years of similar experience, they would be eligible to become an Associate Professor of that broad speciality.&nbsp;</p><div class="pasted-from-word-wrapper"><div class="" id="artmeterpv"></div><div class="articleblock-container" id="arthardpv"></div></div><p style="text-align: justify; ">Earlier, releasing the <a href="https://medicaldialogues.in/topics/teq-2024">Draft Teachers Eligibility Qualifications (TEQ) 2024</a>, the&nbsp;<a href="https://medicaldialogues.in/topics/nmc">National Medical Commission</a>&nbsp;had proposed allowing non-teaching doctors to become Assistant and associate professors if they had working experience in a 220-bedded teaching/non-teaching government hospital. Previously, under the existing TEQ 2022 Regulations, it was required that the non-teaching doctors had working experience at a 330-bed non-teaching hospital.</p><p style="text-align: justify; ">However, previously, the non-teaching doctors were only required to have only two years of work experience at the non-teaching/teaching hospital, the duration of the tenure was increased to 4 years in Draft TEQ 2024.</p><p style="text-align: justify; ">Specifying the norms for non-teaching Consultant/Specialist/Medical Officer working in Government Hospitals, NMC in Clause 3.12 of the Draft TEQ 2024 mentioned, "<i>A non-teaching Consultant/Specialist/Medical Officer, possessing Postgraduate Medical Degree, working for at least four years in a minimum 220 bedded teaching/non-teaching Govermment Hospital shall be eligible to become an Assistant Professor of that broad specialty. They should have completed the Basic Course in Biomedical Research (BCBR) prior to become eligible for such post. The subsequent promotions to higher teaching designations will be as per criteria mentioned in Table IA and 1B of this regulation. They will have to complete the Basic Course in Medical Education Technology (BCMET) Course within three years of such appointment if it is required for the specialty."</i></p><p style="text-align: justify; "><i>"A non-teaching Consultant/Specialist/Medical Officer, possessing Postgraduate Medical Degree, working for at least ten years in the concerned specialty in a minimum 220 bedded teaching/non-teaching Government Hospital shall be eligible to become Associate Professor of that broad specialty. He/She should have completed the Basic Course in Biomedical Rescarch (BCBR) Course prior to become eligible for such post. The subsequent promotions to higher teaching designations will be as per criteria mentioned in Table lA and lB of this regulation. They will have to complete the Basic Course in Medical Education Technology (BCMET) Course within thrce ycars of such appointment if it is required for the specialty,"</i> it added.</p><p style="text-align: justify; ">While the Draft TEQ 2024 has not been finalised yet, a recent media report suggested that aiming to tackle the <a href="https://medicaldialogues.in/topics/faculty-shortage">shortage of faculties</a> in medical colleges, NMC was planning to fill up the vacant faculty positions with retired doctors from the army and the railways.&nbsp;</p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">The Commission is reportedly considering filling at least 700 such vacant positions across government institutes. These teaching faculties- retired doctors from the armed forces, railways, and Employees' State Insurance Corporation, will teach specialised curriculum in the post-graduate courses.</span></p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/faculty-shortage-nmc-plans-to-rope-in-retired-army-railway-doctors-to-teach-specialised-curriculum-147373" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: Faculty Shortage: NMC plans to rope in Retired Army, Railway Doctors to teach specialised curriculum</i></b></a></p>

359. Woman doctor booked for alleged Anti-India social media post

     Wed, 30 Apr 2025 06:53:13 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284991-booked.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Mangaluru: The Mangaluru city police have booked a woman doctor&nbsp;</span>working at a private hospital for her alleged 'anti-India message' on social media.</p><p style="text-align: justify;">In the controversial video post, the medical professional can purportedly be heard saying, “I hate India”.</p><p style="text-align: justify; ">According to the PTI report, city police on Monday said they have taken cognisance of the matter and are verifying the authenticity of the post and the context in which the statement was made.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/state-news/jammu-kashmir/gmc-skims-medicos-booked-for-allegedly-raising-anti-india-slogans-celebrating-paks-victory-against-india-in-t20-world-cup-83672"><b>Also Read:GMC, SKIMS medicos booked for allegedly raising anti-India Slogans, celebrating Pak's victory against India in T20 World Cup</b></a></p><p style="text-align: justify;">“As of now, we are gathering more information and verifying whether the content violates any legal provisions,” a senior police official told PTI.</p><p style="text-align: justify;">As per a media report in the <a href="https://timesofindia.indiatimes.com/city/mangaluru/suo-motu-case-against-doctor-over-social-media-post-in-karnataka/articleshow/120738469.cms" rel="nofollow">TOI</a>, Mangaluru City police commissioner Anupam Agrawal said that police registered a case, and the doctor was called to the station for investigation. As part of the investigation, a notice was served to her to arrive at the station whenever asked. Her mobile phone was confiscated and sent for forensic analysis. A case was registered under sections 353 and 196 of the BNS, he said.</p><p style="text-align: justify;">No formal case has been registered yet, police said, adding that further action will be taken based on the outcome of the preliminary inquiry.</p><p style="text-align: justify;">In response, the hospital distanced itself from the doctor’s remarks and strongly condemned them, stating that the views expressed in the post were harmful to the nation’s interest and did not reflect the institution’s values.&nbsp;</p><p style="text-align: justify;"> <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/bengaluru-doctor-accused-of-throwing-stray-dog-to-death-from-third-floor-147306"><b>Also Read:Bengaluru Doctor accused of throwing stray dog to death from third floor</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

360. AstraZeneca discontinues Phase 3 trial of Truqap in metastatic castration-resistant prostate cancer

     Wed, 30 Apr 2025 06:44:10 -0000

     Truqap was discovered by AstraZeneca subsequent to a collaboration with Astex Therapeutics.

     <img src='https://medicaldialogues.in/h-upload/2025/01/06/267765-prostate-cancer-50-2.webp' /><p><span style="text-align: justify;"><a href="https://medicaldialogues.in/topics/AstraZeneca">AstraZeneca </a>has announced the discontinuation of the CAPItello-280 Phase III trial evaluating the efficacy and safety of Truqap (</span><span style="text-align: justify;">capivasertib) in combination with docetaxel and androgen-deprivation therapy (ADT) compared to docetaxel and ADT with placebo in patients with metastatic castration-resistant prostate cancer (mCRPC).</span></p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">This decision is based on the recommendation of the Independent Data Monitoring Committee (IDMC) following their review of data from a pre-specified interim analysis, which concluded that the Truqap combination was unlikely to meet the dual primary endpoints of radiographic progression-free survival (rPFS) and overall survival (OS) versus the comparator arm upon trial completion. The safety profile for Truqap was consistent with previous trials.</p><p style="text-align: justify; ">"The Company will work with investigators to ensure the necessary follow up with patients. Data from the trial will inform ongoing research," AstraZeneca stated in a release.</p><p style="text-align: justify; "><a href="https://medicaldialogues.in/topics/prostate-cancer">Prostate cancer </a>is the second most prevalent cancer in men and the fifth leading cause of male cancer death globally, with an incidence of more than 1.4 million and over 397,000 deaths in 2022.</p><p style="text-align: justify; ">Metastatic prostate cancer is associated with a significant mortality rate, with only one third of patients surviving five years after diagnosis. Development of prostate cancer is often driven by male sex hormones called androgens, including testosterone.</p><p style="text-align: justify; ">CAPItello-280 is a Phase III, double-blind, randomised trial evaluating the efficacy and safety of Truqap in combination with docetaxel and ADT compared to docetaxel and ADT in combination with placebo in patients with mCRPC.</p><p style="text-align: justify; ">The global trial enrolled 1,033 adult patients with histologically confirmed prostate adenocarcinoma with evidence of mCRPC with progression of disease despite ADT. The dual primary endpoints of the CAPItello-280 trial are rPFS as assessed by investigator and OS in the overall trial population. Key secondary endpoints include OS and rPFS as assessed by investigator in patients with mCRPC and PTEN-deficient tumours, OS and rPFS as assessed by investigator in patients with mCRPC and PTEN-proficient tumours, time to pain progression (TTPP) in the overall trial population and time to first symptomatic skeletal-related event (SSRE) in the overall trial population.</p></div><p style="text-align: justify; ">Truqap is a first-in-class, potent, adenosine triphosphate (ATP)-competitive inhibitor of all three AKT isoforms (AKT1/2/3). Truqap 400mg is administered twice daily according to an intermittent dosing schedule of four days on and three days off. This was chosen in early phase trials based on tolerability and the degree of target inhibition.</p><p style="text-align: justify; ">Truqap in combination with Faslodex (fulvestrant) is approved in the US, EU, Japan, China and several other countries for the treatment of adult patients with HR-positive (or estrogen receptor-positive), HER2-negative locally advanced or metastatic breast cancer with one or more biomarker alterations (PIK3CA, AKT1 or PTEN) following recurrence or progression on or after an endocrine-based regimen based on the results from the CAPItello-291 trial. Truqap is also approved in Australia for the treatment of adult patients with HR-positive, HER2-negative locally advanced or metastatic breast cancer following recurrence or progression on or after an endocrine based regimen based on these trial results.</p><p style="text-align: justify; ">Truqap is being evaluated in ongoing Phase III trials for the treatment of breast and prostate cancers.</p><p style="text-align: justify; ">Truqap was discovered by AstraZeneca subsequent to a collaboration with Astex Therapeutics (and its collaboration with the Institute of Cancer Research and Cancer Research Technology Limited).</p>

361. NBE Invites Applications for Diploma Final Exams June 2025, details

     Wed, 30 Apr 2025 06:28:31 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284990-application-invited.webp' /><p style="text-align: justify; "><b>New Delhi-</b> Through a notice, the National Board of Examinations in Medical Sciences (NBEMS) has invited online applications for the NBEMS Diploma Final Examination June 2025.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">As per the notice, NBEMS is going to conduct the NBEMS Diploma Final Theory Examination - June 2025 on 09th, 10th and 11th June 2025 on a computer-based platform at various examination centres across the country. </p><p dir="ltr" style="text-align: justify; ">On this, the online submission of the application form for the theory and practical exam and practical exam only will be available from today, i.e., April 30, 2025, 03:00 PM to May 20, 2025, 11:55 PM on the official website of NBEMS.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/fmge-june-2025-registration-live-fee-payment-guidelines-explained-147479"><b>Also Read:&nbsp;</b>FMGE June 2025 Registration Live: Fee, Payment guidelines Explained</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">The information bulletin will also be available from today, i.e., April 30, 2025, 03:00 PM, on the official website of NBEMS for the candidates willing to appear for the NBEMS Diploma Final Examination June 2025. The information bulletin will contain important details such as eligibility, exam scheme, schedule, application process, fees, etc.</p><p dir="ltr" style="text-align: justify; "><b><u>STEPS TO FILL OUT THE NBEMS DIPLOMA FINAL EXAM JUNE APPLICATION FORM 2025</u></b></p><p dir="ltr" style="text-align: justify; "><b>STEP 1- </b>Visit the official NBE website.</p><p dir="ltr" style="text-align: justify; "><b>STEP 2-</b> Register with a valid email ID and mobile number.</p><p dir="ltr" style="text-align: justify; "><b>STEP 3-</b> Fill out the application form with personal, academic, and contact details.</p><p dir="ltr" style="text-align: justify; "><b>STEP 4-</b> Upload required documents such as a passport-size photograph, signature, and degree certificates.</p><p dir="ltr" style="text-align: justify; "><b>STEP 5- </b>Pay the application fee online.</p><p dir="ltr" style="text-align: justify; "><b>STEP 6-</b> Submit the application form and take a printout for future reference.</p><p dir="ltr" style="text-align: justify; ">The National Board of Examinations (NBE) was established in 1975 in New Delhi. It is an autonomous entity within the Ministry of Health and Family Welfare, Government of India. NBE conducts a few examinations, such as DNB final (exit) examinations, Fellowship Entrance and Exit examinations, NEET-SS for admission to DM/Mch/DrNB superspecialty medical courses across India, etc.</p><p dir="ltr" style="text-align: justify; "><b><u><i>To view the notice, click the link below</i></u></b></p><p dir="ltr" style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/nbe-invites-applications-for-diploma-final-exam-june-2025jpg-284994.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/nbe-invites-applications-for-diploma-final-exam-june-2025jpg-284994.pdf</a></p></div><div class="pasted-from-word-wrapper"><div></div></div>

362. Cabinet to decide on Free MRIs at all Delhi Govt Hospitals

     Wed, 30 Apr 2025 06:15:21 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284988-rekha-gupta-1.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">New Delhi: In a bid to strengthen health infrastructure, the Delhi government is expected to decide on key proposals in a&nbsp;</span>meeting scheduled on Tuesday, including outsourcing of staff through PSUs and installing MRI machines in hospitals under a PPP model, official sources said.</p><p style="text-align: justify; ">The proposals will be discussed in the Cabinet meeting chaired by Chief Minister <a href="https://medicaldialogues.in/topics/rekha-gupta" target="_blank">Rekha Gupta</a>, scheduled for 12 noon, they said, news agency PTI reported.</p><p style="text-align: justify;">The Health Department seeks to centralise the outsourcing of staff required for documentation and other formalities at government hospitals and other health facilities of the government by roping in public sector undertakings (PSUs), they said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/ayushman-vay-vandana-delhi-launches-rs-10-lakh-health-cover-for-senior-citizens-147480"><b>Also Read:Ayushman Vay Vandana: Delhi launches Rs 10 lakh health cover for Senior Citizens</b></a></p><p style="text-align: justify;">Presently, the hospitals and other facilities like clinics hire these personnel through private placement entities, said an official.</p><p style="text-align: justify;">The other proposal is regarding the installation of magnetic resonance imaging (MRI) machines through a public-private partnership to meet the growing demand for such crucial scans, he said.</p><p style="text-align: justify;">There is a shortage of MRI machines in government hospitals, which needs to be immediately addressed to ensure that patients are not forced to get these tests done from expensive private facilities, he added, reports PTI.</p><p style="text-align: justify;">As per a media report in the <a href="https://timesofindia.indiatimes.com/city/delhi/govt-may-outsource-front-desk-ops-to-psus-in-state-hosps/articleshow/120705764.cms" rel="nofollow">TOI</a>, "Referring patients to a doctor in OPD or admitting them to hospital for treatment requires a lot of details from the kin and documentation to ensure they get the benefits of all schemes as per their eligibility. The govt has thus decided to engage a public sector undertaking to provide manpower for the purpose," said an official, requesting anonymity.</p><p>"We will begin the process of engaging a company to provide manpower as soon as the cabinet accords approval to the proposal," the official added. There are 39 state-run hospitals in the capital.&nbsp;</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/shortage-of-senior-junior-residents-at-delhi-aiims-mos-health-informs-parliament-145659" style="background-color: rgb(249, 249, 249); text-align: justify;"><b>Also Read:Shortage of Senior, Junior Residents at Delhi AIIMS: MoS Health informs Parliament</b></a><br></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

363. Ragging at Pune’s BJ Medical College: Orthopaedics PG medicos Suspended, expelled from hostel

     Wed, 30 Apr 2025 06:10:33 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/24/275778-ragging.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Pune: Taking<span style="background-color: rgb(255, 255, 255);">&nbsp;disciplinary action, BJ Medical College, Pune, has suspended three second-year postgraduate students from the Orthopaedics Department and evicted them from the hostel for allegedly ragging juniors.</span></p></div><div class="pasted-from-word-wrapper"><p>The action followed a formal complaint received by the college on Monday, alleging that the second-year PG students had subjected four juniors to mental and physical harassment, including the use of threatening language. A committee was promptly formed to investigate the allegations</p><p style="text-align: justify; ">Speaking to PTI on the incident, an official from the medical college said, "Three postgraduate students of the state-run <a href="https://medicaldialogues.in/topics/b-j-medical-college" target="_blank">BJ Medical College</a> in Pune have been suspended and removed from their hostel for allegedly <a href="https://medicaldialogues.in/topics/ragging" target="_blank">ragging </a>junior doctors."</p><p style="text-align: justify; ">The college took action after it received a complaint against three second-year PG students from the Orthopaedic Department, said Dr Eknath Pawar, dean of the medical college, which is attached to the <a href="https://medicaldialogues.in/topics/sassoon-general-hospital" target="_blank">Sassoon General Hospital</a>.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-colleges/kmcri-ragging-5-mbbs-students-suspended-for-forcing-juniors-to-attend-classes-as-proxies-145086"><b>Also Read:KMCRI ragging: 5 MBBS students suspended for forcing juniors to attend classes as proxies</b></a></p><p style="text-align: justify;">Sources in the medical college told PTI that the accused targeted four junior medical students from their department. They allegedly harassed the juniors mentally, sometimes physically, and even used intimidating language, said the sources.</p><p style="text-align: justify;">“The parents of the students first approached Mantralaya (state secretariat) in Mumbai. On Monday, the college authorities received a complaint. We formed a committee to investigate the matter. Based on the findings, three PG students were suspended and removed from their hostel,” said Pawar.</p><p style="text-align: justify;">A probe is underway, he added.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-colleges/gmc-nagarkurnool-3-mbbs-students-suspended-for-ragging-146014"><b>Also Read:GMC Nagarkurnool 3 MBBS students suspended for ragging</b></a></p><p style="text-align: justify;">Medical Dialogues had earlier reported taking cognisance of a ragging complaint, the Government Medical College (GMC), Nagarkurnool suspended three senior MBBS students for allegedly physically harassing, beating and slapping a first-year junior student in a hostel room. An FIR had also been registered against the accused in connection with the case.</p><p>Among the three, one student (Third year) had been suspended for three months, who was reported to be the main culprit, while the other two (Second year) received suspensions of one month.</p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

364. Zydus Lifesciences wins USFDA okay for cholesterol-lowering drug Niacin Extended Release

     Wed, 30 Apr 2025 05:45:50 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/12/282750-medicine-50-1.webp' /><p><b style="text-align: justify;">Ahmedabad:&nbsp;</b><span style="text-align: justify; background-color: rgb(255, 255, 255);"><a href="https://medicaldialogues.in/topics/zydus-lifesciences">Zydus Lifesciences Limited</a> has announced that the company has received final approval from the United States Food and Drug Administration (USFDA) to manufacture Niacin Extended-Release Tablets USP, 500 mg, 750 mg, and 1,000 mg (Niaspan Extended-Release Tablets, 500 mg, 750 mg, and 1,000 mg).</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Niacin is indicated to reduce elevated total <a href="https://medicaldialogues.in/topics/cholesterol">cholesterol </a>(TC), LDL cholesterol (LDL-C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase HDL cholesterol (HDL-C) in patients with primary hyperlipidaemia and mixed dyslipidaemia. It is also indicated to reduce the risk of recurrent myocardial infarction in patients with a history of myocardial infarction and hyperlipidaemia and to reduce TG in adult patients with severe hypertriglyceridemia. </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Niacin-Extended-Release tablets will be produced at the Group’s manufacturing site at Moraiya, Ahmedabad. </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Niacin-Extended-Release tablets had annual sales of USD 5.5 mn in the United States (IQVIA MAT February 2025). </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> The group now has 425 approvals and has so far filed 492 ANDAs since the commencement of the filing process in FY 2003-04.</span></p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/zydus-lifesciences-inks-pact-with-pai-partnersother-shareholders-to-buy-majority-stake-in-amplitude-surgical-sa-147330">Zydus Lifesciences inks pact with PAI Partners, other shareholders to buy majority stake in Amplitude Surgical SA</a></i></b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify; "><p>Zydus Lifesciences Ltd. is an innovative, global lifesciences company that discovers, develops, manufactures, and markets a broad range of healthcare therapies. The group has a significant presence in cancer related therapies and offers a wide range of solutions with cytotoxic, supportive &amp; targeted drugs.</p><p><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/medical-devices/zydus-medtech-braile-biomedica-of-brazil-ink-global-licensing-pact-to-commercialise-tavi-technology-146842">Zydus Medtech, Braile Biomedica of Brazil ink global licensing pact to commercialise TAVI technology</a></i></b></p></div></div><div class="pasted-from-word-wrapper"><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify; "><br></p></div></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify; "><p><br></p></div></div>

365. 50 per cent salary cut for Contractual Medical officers, Rajasthan Govt faces backlash

     Wed, 30 Apr 2025 05:00:03 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/20/275101-doctor-salary.webp' /><p style="text-align: justify; "><b>Jaipur: </b>In a recent job notification that went viral on social media, the <a href="https://medicaldialogues.in/topics/rajasthan-government" target="_blank">Rajasthan government</a> has announced that contractual Allopathy Medical Officers will now receive a monthly salary of Rs 28,050. This decision has drawn widespread criticism from the medical community, as it is a major cut from the previous salary of Rs 56,000 per month.&nbsp;</p><p style="text-align: justify; ">The official advertisement, signed by the Mission Director on April 17, 2025, under the National Health Mission (NHM), announced 162 vacancies for Allopathy Medical Officers. To be eligible, candidates must have an MBBS degree from a recognised institution, completed a mandatory rotatory internship, and be registered with the Rajasthan Medical Council. For this, the government will only pay them Rs 28,050 monthly.&nbsp;</p><p style="text-align: justify; ">The significant salary cut has angered doctors across the state, who believe they deserve fair pay for the critical role they play in every emergency, saving countless lives. After investing years of hard work and a large amount of money into completing their medical education, they feel disrespected and frustrated by such a low amount.</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/news/health/doctors/salary-hike-wb-senior-residents-to-now-get-rs-15000-more-junior-doctors-rs-10000-143861" target="_blank"> Salary Hike! WB Senior Residents to now get Rs 15,000 MORE, Junior Doctors Rs 10,000</a></b></p><p style="text-align: justify; ">Previously, doctors who were employed on a contract basis were earning Rs 56,000 per month, but with the new salary structure, the pay has been slashed by almost 50 per cent. This has come as a major disappointment for doctors, especially at a time when healthcare workers have been demanding better pay and improved working conditions in the public health system for a long time.&nbsp;</p><p style="text-align: justify; ">Slamming the state government for giving such a low salary, several doctors took to social media to express their frustration. They strongly criticised the significant pay cut for MBBS doctors, especially when compared to other welfare schemes where beneficiaries earn more.</p><p style="text-align: justify; ">The recruitment notice going viral on the internet and igniting rage among doctors states, <i>"In accordance with the above reference and under the provisions of the Rajasthan Contractual Hiring to Civil Posts Rules, 2022, approval is hereby granted to proceed with the recruitment for vacant contractual posts under NHM through the District Health Committee, considering the urgent need for human resources and operational efficiency. Approval has been received from the Finance Department’s letter No. 152500633 dated 29.03.2025. Recruitment may be carried out either through a walk-in process or on a merit basis no later than 30.03.2026, and action must be taken at the district level accordingly."</i></p><p style="text-align: justify; ">The notice also adds that the government is planning to recruit a total of 2,855 health workers under NHM. The posts include Allopathy Medical Officers, Female Health Workers, Nurses, Lab Technicians, Pharmacists, and Radiographers. All appointments will be made at the district level by the respective health committees.</p><p style="text-align: justify; ">Along with medical officers, 159 posts have also been announced for Female Health Workers, with a monthly pay of Rs 13,150. Applicants for this role must have completed the Auxiliary Nurse Midwifery (ANM) training or Health Worker Female course and must be registered with the Rajasthan Nursing Council as a B Grade Nurse.</p><p style="text-align: justify; ">The government has also announced the hiring of 1,941 nurses at a monthly pay of Rs 18,900. Applicants must have completed their senior secondary education and hold a GNM diploma or equivalent qualification, along with registration in the Rajasthan Nursing Council. Additionally, the government is recruiting for 414 Lab Technician posts, 151 Pharmacist posts, and 28 Radiographer posts, each offering a salary of Rs 13,150 per month.&nbsp;</p><p style="text-align: justify; ">With the new salary structure, healthcare workers have raised concerns that such a drastic pay cut could affect the morale of doctors and their willingness to work passionately. Not only doctors but also the general public slammed the government for paying such low salaries to the healthcare workers.&nbsp;</p><p style="text-align: justify; ">Sharing the information, one doctor wrote on X (formerly Twitter), “In a shocking move, the Rajasthan government has slashed the monthly salary of contractual doctors from ₹56,000 to ₹28,050, contrary to expectations of a hike. Can it improve the health structure?</p><p style="text-align: justify; ">Similarly, Dr Harshad Sharma, State executive member at Indian Medical Association (IMA), said in a tweet, "This decision is completely contrary to the previous orders. On March 30, 2022, the then Mission Director, Dr. Jitendra Kumar Soni had fixed the salary of full-time contract doctors at Rs 56,600. Even in another order issued on March 1, 2024, the same salary was fixed for contract doctors.</p><p style="text-align: justify; ">However, the old doctors will continue to get a salary of Rs 56,600, but the new doctors will get a reduced amount. Experts say that after deducting the contract part, this amount will be only around Rs 25,000. The government's decision to cut doctors' salaries by up to 50% is not just an administrative order but a blatant insult to our dedication, sacrifice and spirit of service to humanity. This decision is not only an economic injustice but also a deep blow to the dignity of an ideal profession like medicine. We are the ones who sacrificed our youth under the burden of books, the ones who sacrificed their sleep, festivals, family and personal happiness to save the lives of unknown faces, the same people who risked their lives to protect the country during the storm of the pandemic."</p><p style="text-align: justify; ">Dr Lakshya Mittal, National President of United Doctors Front (UDF), tweeted, "Rajasthan- The first state in India where medical education was made a joke. Faculty from YouTube, study by yourself, job on contract, and the salary of Rs 56100 is now only Rs 25000."</p><p style="text-align: justify; ">Medical Dialogues had previously reported that despite completing their postgraduate degrees, the doctors in 13 different specialities in Rajasthan are unable to contribute to the State public health sector as the Rajasthan Government has not created any posts of junior specialists, senior specialists, and principal specialists in those specialities in its hospitals.&nbsp;</p><p style="text-align: justify; ">These specialities include biochemistry, radiation oncology, transfusion medicine, preventive and social medicine, emergency medicine, physical medicine and rehabilitation, palliative medicine, anatomy, physiology, pharmacology, nuclear medicine, family medicine, and hospital administration.</p><p style="text-align: justify; ">Even though the MBBS doctors have completed their post-graduation in these 13 different specialities in the State's medical colleges and many are studying the courses, there is not a single approved position in those 13 specialities in medical colleges, district and sub-district hospitals.</p><p style="text-align: justify; ">Due to this, neither the people nor the State Government are able to utilise the money invested in the specialised education of the doctors studying these specialities. On the other hand, the medical students who are pursuing their PG degrees in these specialities are also worried about their future due to the limited opportunities to work in the State.</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/doctors/rajasthans-healthcare-paradox-trained-doctors-but-no-jobs-in-13-specialities-146372" target="_blank">Rajasthan's Healthcare Paradox: Trained Doctors, But No Jobs in 13 specialities</a></b></p>

366. 2 nursing students die in car accident, 3 injured

     Wed, 30 Apr 2025 04:00:52 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/26/280354-accident-1.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Hyderabad: In an unfortunate incident, two nursing students died in a car accident in&nbsp;</span>Telangana's Gadwal town recently. Two female students died on the spot, while three others were critically injured.</p><p>As per the IANS report, a<span style="text-align: justify;">&nbsp;car ran amok in Telangana's Gadwal town on Tuesday, killing two nursing students and injuring some others.</span></p><p style="text-align: justify;">The incident occurred on Tuesday evening when students of a nursing college were waiting for a bus at a bus stop to go to their hostel.</p><p style="text-align: justify;">According to police, the SUV rammed into the students waiting at the Housing Board Turning Bus Stop in the Gadwal district headquarters.</p><p style="text-align: justify; ">Two female students died on the spot, while three others were critically injured. They were shifted to the government hospital, where the condition of two of them is stated to be critical.</p><p style="text-align: justify;">Two children, who were also waiting at the bus stop, sustained grievous injuries and were also admitted to a hospital.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/state-news/madhya-pradesh/nursing-student-dies-two-injured-in-accident-in-bhopal-145562"><b>Also Read:Nursing Student Dies, Two Injured in Accident in Bhopal</b></a></p><p style="text-align: justify;">The deceased have been identified as Maheshwari, a resident of Makthal, and Manisha, who hailed from Wanaparthy.</p><p style="text-align: justify;">After the accident, the SUV driver escaped from the spot, leaving behind the vehicle. Locals said the driver lost control of the vehicle as he was drunk.</p><p style="text-align: justify;">Police officials rushed to the spot and shifted the injured to the hospital. The bodies of the two deceased students were also shifted to the mortuary at the government hospital for autopsy.</p><p style="text-align: justify;">Police registered a case and took up an investigation. A police officer said they were trying to apprehend the person who was driving the vehicle, reports IANS.</p><p style="text-align: justify;">The incident sent shock waves among parents of the students of the nursing college.</p><p style="text-align: justify;">Gadwal MLA Bandla Krishna Mohan Reddy, district Collector B. M. Santosh and Superintendent of Police T. Srinivasa Rao visited the government hospital.</p><p style="text-align: justify;">Health Minister Damodar Raja Narasimha has expressed shock over the accident. He condoled the death of two nursing students. He spoke to the Gadwal MLA over the phone.</p><p style="text-align: justify;">The Minister directed officials to ensure the best possible treatment to the injured. He also asked them to provide assistance to the families of the deceased students.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/state-news/himachal-pradesh/bsc-nursing-student-death-mandi-police-registers-murder-case-137882"><b>Also Read:BSc Nursing Student Death: Mandi Police Registers murder Case</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

367. Is mere presence during surgery enough to prosecute? HC Clears Gynaecologist in Alleged Kidney Removal Case

     Wed, 30 Apr 2025 04:00:13 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/05/16/238378-patna-hc.webp' /><p style="text-align: justify; "><b>Patna:</b>&nbsp;Granting relief to a <a href="https://medicaldialogues.in/topics/gynaecologist">gynaecologist</a>, the Patna High Court recently quashed all criminal proceedings against her in a&nbsp;<a href="https://medicaldialogues.in/topics/Medical%20Negligence">medical negligence</a> case dating back to 2003, where a patient had alleged that his right kidney was removed without consent by the treating doctors.&nbsp;</p><p style="text-align: justify; ">After taking note of the report by PGI Chandigarh, the HC bench comprising Chandra Shekhar Jha set aside the order dated 23.02.2025 by the Sessions Judge, Patna, which had dismissed the application for discharge filed by the petitioner under Section 227 of the Cr.PC.</p><p style="text-align: justify; ">The history of the case goes back to 2000, when the complainant was suffering from abdominal pain, and later he alleged that his right kidney was removed without consent during treatment by Dr. Sinha, a surgeon. He alleged that due to this, he due was suffering from various medical complications. Dr. Sinha's wife, a gynaecologist, was present during the surgery as a part of the medical team, and later she was also named a co-accused in the case.</p><p style="text-align: justify; ">Taking note of the complaint, the Jurisdictional Magistrate committed the case before the trial court under Section 209 of the Cr.P.C. for the trial. When the trial court dismissed the application for discharge filed by the gynaecologist, she approached the High Court challenging the order.</p><p style="text-align: justify; ">The counsel for the petitioner submitted that the petitioner is a gynaecologist by profession and there was no need for her presence during the operation, where it had been alleged that the complainant's right kidney was removed. It was further submitted that the operation was conducted by the petitioner's husband, who is a surgeon. However, out of oblique motive, the petitioner was made an accused in this case.</p><p style="text-align: justify; ">Further, the counsel pointed out that the petitioner had earlier moved before the court for constituting a Medical Board to seek an expert opinion regarding the alleged medical negligence and it was rejected by the order dated 11.10.2010.</p><p style="text-align: justify; ">He also submitted that for further testing to ascertain that it was a case of kidney removal or absence since birth, a Medical Board was constituted under the Chairmanship of the HoD, Nephrology, <a href="https://speciality.medicaldialogues.in/topics/pgimer">PGIMER</a>, Chandigarh, where after going through CT Pyelography/Cystoscopy, it was categorically stated that the right kidney of the complainant was not removed, rather, it was found shrunken and severely atrophic.</p><p style="text-align: justify; ">On the other hand, the complainant's counsel submitted that the petitioner's husband had categorically recorded that the complainant's right kidney was present before surgery in 2000. The complainant was treated for “Chyluria”, where the pyelolymphatic duct was operated for milky discharge of urine. It is submitted that after operation, the complainant developed&nbsp; "pain and, thereafter, he was treated with another physician. During the treatment, he came to know that his right kidney was not visible and later the report of AIIMS New Delhi and Mahavir Cancer Sansthan, Patna also suggested that the right kidney was not visible.</p><p style="text-align: justify; ">While considering the matter, the HC bench perused the medical report of Postgraduate Institute of Medical Education and Research, Chandigarh dated 16.03.2016, which recorded that <i>"In view of findings on cystoscopy, retrograde ureteropyelography and CT Pyelography, the committee concluded that the right kidney of Mr. *** was not removed. However, it is shrunken and severely atrophic."</i></p><p style="text-align: justify; ">Taking note of this, the HC bench observed, <i>"The aforesaid report of P.G.I., Chandigarh suggests that the complainant left the test for a long period and has made himself available only in the year-2016 to get it concluded. It also appears that none of the radiological tests prior to P.G.I., Chandigarh suggests that it was a case of kidney removal rather it only suggest that the right kidney of O.P. No.2 is not visualized."</i></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">Referring to the previous orders passed by the Supreme Court, the HC bench observed that the petitioner gynaecologist, was only present during the operation and therefore all criminal proceedings against her were liable to be dismissed.</span></p><blockquote style="text-align: justify; "><i><span style="background-color: rgb(255, 255, 255);">"</span>Considering the aforesaid factual and legal submissions and by taking note of facts, as admittedly the petitioner is the wife of Dr. *** Sinha, who conducted the operation upon O.P. No.2 on 13.09.2000, where petitioner was only said to be present and further by taking note of the report of P.G.I., Chandigarh, which is a document of unimpeachable character, therefore, taking note of Devendra Nath Padhi case, Bhajan Lal Case and other legal reports as discussed, this Court is of the opinion that the impugned order dated 23.02.2024 as passed by learned Additional Sessions JudgeX, Patna in Sessions Trial No.440 of 2023 arising out of Complaint Case No.1750(c) of 2003 along with all its consequential proceedings qua petitioner is fit to be set aside/quashed to secure the ends of justice,"</i> ordered the Court.</blockquote><p style="text-align: justify; "><i>"Hence, the impugned order dated 23.02.2024 with all its consequential proceedings qua petitioner as passed by learned Additional Sessions Judge-X, Patna in Sessions Trial No.440 of 2023 arising out of Complaint Case No.1750(c) of 2003, is hereby set aside/quashed,"</i> it further noted.</p><p style="text-align: justify; "><b><i>To view the order, click on the link below:</i></b></p><p style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/patna-hc-order-285020.pdf"><b><i>https://medicaldialogues.in/pdf_upload/patna-hc-order-285020.pdf</i></b></a></p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/kamineni-hospitals-found-vicariously-liable-for-medical-negligence-in-patients-death-147245" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: Kamineni Hospitals found vicariously liable for medical negligence in patient's death</i></b></a></p>

368. Statin use may improve survival in patients with some blood cancers: Study

     Wed, 30 Apr 2025 03:30:27 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/06/30/213167-statins.webp' /><p style="text-align: justify; ">Patients with<a href="https://medicaldialogues.in/topics/chronic%20lymphocytic%20leukemia"> chronic lymphocytic leukemia</a> (CLL) or <a href="https://medicaldialogues.in/topics/small%20lymphocytic%20lymphoma">small lymphocytic lymphoma </a>(SLL) who were taking cholesterol-lowering <a href="https://medicaldialogues.in/topics/Statin">statin</a> medications at the start of their <a href="https://medicaldialogues.in/topics/cancer">cancer</a> treatment had a 61% lower risk of dying from their cancer compared to similar patients who were not taking statins, according to a study published today in the journal <i>Blood Advances</i>. </p><p style="text-align: justify;">“This is the first systematic evaluation of the association of statin use with survival outcomes in patients with CLL or SLL who have been treated with contemporary targeted agents such as <a href="https://medicaldialogues.in/topics/ibrutinib">ibrutinib</a>,” said the study’s principal investigator, Ahmad Abuhelwa, PhD, an assistant professor of pharmacy practice and pharmacotherapeutics at the University of Sharjah in the United Arab Emirates. “Our results highlight a strong link between statin use and improved survival in this patient population.” </p><p style="text-align: justify;">CLL is a slow-growing cancer that starts in the blood-forming cells of the bone marrow and is the most common form of leukemia in adults in the United States. SLL, also a slow-growing cancer, affects the same type of cells as CLL but starts in lymphoid tissues such as the spleen instead of in the blood-forming cells. </p><p style="text-align: justify;">Statins are among the most widely prescribed medications. It’s estimated that over 90 million adults in the United States take a statin drug to reduce their cholesterol levels and lower their risk for heart disease, which can lead to heart attacks or strokes. Previous studies have linked statin use to reduced death rates from several cancers, including CLL, said Dr. Abuhelwa. However, those studies did not evaluate the effects of statin use in patients who were treated with newer cancer therapies such as the targeted drug ibrutinib, he said. </p><p style="text-align: justify;">In the current study, Dr. Abuhelwa and his colleagues analyzed data from 1,467 patients with CLL or SLL who participated in four international clinical trials conducted between 2012 and 2019. In these trials, patients were randomly assigned to treatment with ibrutinib either alone or in combination with other anti-cancer drugs, or to a drug regimen that did not include ibrutinib. A total of 424 patients (29%) were taking a statin at the time they started treatment across the four clinical trials. The median patient age was 65, and 66% were men; 92% had CLL, which was either newly diagnosed, had come back, or had not responded to prior treatment. </p><p style="text-align: justify;">The study’s primary endpoints were cancer-specific survival (how long patients lived after starting treatment before dying specifically from their cancer), overall survival (how long patients lived after starting treatment, regardless of the cause of death), and progression-free survival (how long patients lived after starting treatment before their cancer worsened or they died from any cause). The secondary endpoint was the proportion of patients who experienced severe or life-threatening adverse events. The median follow-up time for all patients enrolled in the four trials was five years for overall survival and 22 months for progression-free survival. </p><p style="text-align: justify;">To account for potential confounding factors, the investigators adjusted their analysis for variables including each patient’s diagnosis, age, sex, weight, physical functioning (as assessed by doctors), disease severity, length of time since their diagnosis, number of co-existing illnesses, use of other medications for heart conditions or high blood pressure, and the specific anti-cancer treatment regimen received. </p><p style="text-align: justify;">Results showed that, regardless of any of these factors, patients who took a statin had, on average, a 61% reduced risk of dying from their cancer, a 38% reduced risk of death from any cause, and a 26% reduced risk of disease progression. Importantly, statin use did not increase the likelihood of severe or life-threatening adverse events. </p><p style="text-align: justify;">“These findings don’t allow us to say for certain that statins directly improve cancer outcomes,” said Dr. Abuhelwa. “However, the fact that this association remained strong even after accounting for multiple factors makes it an important area for future research.” As next steps, he recommended conducting laboratory studies to better understand how statins may influence cancer biology, as well as prospective clinical trials in which patients with CLL or SLL are randomly assigned to take a statin or not. </p><p style="text-align: justify; ">The study has several limitations given its observational nature. For example, patients enrolled in clinical trials tend to be monitored more closely than those who receive treatment outside of a clinical trial, so the study findings may not be generalizable to patients treated in non-clinical trial settings. Additionally, because patients used various statins at different doses, the study could not determine the effects of specific statin types, doses, or duration of use on patients’ survival. </p><p style="text-align: justify; ">“While our results are very promising, we can’t recommend starting statins for CLL/SLL treatment based on this study alone,” Dr. Abuhelwa said. “Future clinical trials are needed to determine definitively whether statins have a direct benefit on cancer survival.”&nbsp;</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Ahmad Y Abuhelwa, Sara A Almansour, Jennifer R. Brown, Humaid O Al-Shamsi, Ziad Abuhelwa, Zelal Kharaba, Yasser Bustanji, Mohammad H Semreen, Salma M. Ali, Ahmad Alhuraiji, Ross A McKinnon, Michael J Sorich, Karem H Alzoubi, Ashley M Hopkins, Statin use and survival in SLL/CLL treated with ibrutinib: Pooled analysis of four randomized controlled trials, Blood Advances, https://doi.org/10.1182/bloodadvances.2024015287</p>

369. Invasive Coronary Function Testing Safe and Effective for Diagnosing Vasomotor Dysfunction in ANOCA Patients: Study

     Wed, 30 Apr 2025 03:15:28 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/26/276127-coronary-function-test.webp' /><p style="text-align: justify; ">Netherlands: A recent study published in <em>JAMA Cardiology </em>has demonstrated that coronary function testing (CFT) is a feasible and safe procedure across various healthcare settings. The findings highlight the high <a href="https://medicaldialogues.in/topics/diagnostic-modalities">diagnostic yield </a>of the test, reinforcing its role in assessing coronary vasomotor function.&nbsp;</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Notably, the study also found that invasive coronary functional testing to identify the cause of angina in patients with<a href="https://medicaldialogues.in/topics/anoca"> nonobstructive coronary artery disease (ANOCA) </a>can be safely performed at highly experienced and less-experienced centers, further supporting its broader clinical applicability.</p><p style="text-align: justify; ">"The invasive testing was conducted across 15 tertiary and nontertiary hospitals in the Netherlands, yielding a high diagnostic success rate. <a href="https://medicaldialogues.in/topics/coronary-artery-spasm">Spasm </a>emerged as the most common ANOCA endotype, while the procedure was associated with low rates of both major and minor complications," the researchers reported. </p><p style="text-align: justify; ">The researchers note that patients with angina and no obstructive coronary artery disease often have coronary vasomotor dysfunction, including epicardial spasm, microvascular spasm, and microcirculatory dysfunction. Invasive coronary function testing effectively diagnoses these endotypes and has previously been deemed safe in expert tertiary centers. Considering this, Caïa Crooijmans, Department of Cardiology Radboudumc, Nijmegen, the Netherlands, and colleagues aimed to assess the prevalence of vasomotor dysfunction in clinically referred ANOCA patients while evaluating the safety and feasibility of coronary function testing. </p><p style="text-align: justify; ">For this purpose, the researchers conducted a quality improvement study using the Netherlands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT), a prospective observational registry involving 15 hospitals, including two tertiary and 13 nontertiary centers. The study included patients with angina and no obstructive coronary artery disease who were referred for a clinically indicated coronary function test (CFT) between December 2020 and January 2024. A complete CFT comprised of acetylcholine spasm provocation testing and the assessment of microcirculatory function. The study evaluated the prevalence of different endotypes based on test results while also assessing the overall safety of the procedure. </p><p style="text-align: justify; "><strong>The investigation uncovered the following findings:</strong></p><ul><li style="text-align: justify; "> 1,207 patients were included, with 978 (81%) females. The mean age of participants was 60 years.</li><li style="text-align: justify; ">Coronary vasomotor dysfunction was highly prevalent, affecting 78% of patients.</li><li style="text-align: justify; ">Major complications were reported in 11 cases (0.9%), while minor complications occurred in 10 of the cases (0.8%).</li><li style="text-align: justify; ">Among these, three major and all minor complications were directly related to the coronary function test.</li><li style="text-align: justify; ">No cases of procedural death, myocardial infarction, or stroke were observed.</li><li style="text-align: justify; ">The occurrence of complications was similar between tertiary and nontertiary centers.</li></ul><p style="text-align: justify; ">The researchers found coronary function testing is feasible and safe across tertiary and nontertiary centers, demonstrating a high diagnostic yield. Their findings suggest considering CFT for all patients with angina and no obstructive coronary artery disease, given its effectiveness in identifying vasomotor dysfunction, which was present in 78% of cases.</p><p style="text-align: justify; ">"Conducted within the Dutch NL-CFT network, the study reported a very low overall complication rate of 1.7%, reinforcing the procedure’s safety. With no observed cases of procedural death, myocardial infarction, or stroke, and comparable complication rates across different healthcare settings, the results support broader clinical adoption of CFT for improved diagnosis and management of coronary vasomotor dysfunction," the researchers wrote.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Crooijmans C, Jansen TPJ, Meeder JG, et al. Safety, Feasibility, and Diagnostic Yield of Invasive Coronary Function Testing: Netherlands Registry of Invasive Coronary Vasomotor Function Testing. JAMA Cardiol. Published online February 19, 2025. doi:10.1001/jamacardio.2024.5670</p></div><p style="text-align: justify; "><br></p>

370. Smoking, high BP and diabetes independently linked to peripheral vascular disease, suggests study

     Wed, 30 Apr 2025 03:15:06 -0000

     <img src='https://medicaldialogues.in/h-upload/2022/08/18/183583-peripheral-vascular-disease.webp' /><p style="text-align: justify; ">A new study published in the journal of <i>Cureus</i> showed that smoking, diabetes, and high blood pressure are independent risk factors for peripheral vascular disease (PVD) in Northeast India that are specific to a certain location.</p><p style="text-align: justify; ">Peripheral arterial disease (PAD) is the subject of this study because of its increased rates of morbidity and mortality associated with cardiovascular fatalities. The majority of research on PVD risk factors comes from Western nations, with little information accessible in developing nations like India. This study was set to examine the different risk factors most frequently linked to peripheral vascular disease in a northeastern Indian tertiary care hospital because there is a severe paucity of data on PVD in this area.</p><p style="text-align: justify; ">Finding risk variables in patients with PVD was the goal of this hospital-based case-control research, which was carried out in both retrospective and prospective modalities. From January 2015 to January 2025, a tertiary care teaching hospital in Northeast India served as the study's site. Group A consisted of individuals with PVD, while Group B consisted of healthy volunteers who did not have PVD. </p><p style="text-align: justify; ">The study examined the course of the disease and the results of treatment over a ten-year period (January 2015–January 2025). It included prospective data (October 2020–January 2025) from a questionnaire survey and follow-ups, as well as retrospective data (January 2015–October 2020) from hospital records.</p><p style="text-align: justify; ">A total of 688 controls and 172 cases, at a 1:4 ratio, took part in the study. When compared to controls, cases had considerably higher rates of hypertension, diabetes mellitus, smoking history, and cardiac conditions. Peripheral vascular disease was substantially correlated with smokers' daily cigarette consumption and smoking duration. The risk of peripheral vascular disease was considerably raised when smoking was coupled with diabetes mellitus and hypertension.</p><p style="text-align: justify; ">The most prevalent vascular pathology was atherosclerosis below the aortic bifurcation, which was detected in 104 patients (60.47%), followed by thromboangiitis obliterans in 63 individuals (36.63%). Male gender, smoking history, daily cigarette use, diabetes mellitus, and hypertension were all found to be distinct risk factors for peripheral vascular disease using multivariate logistic regression analysis.</p><p style="text-align: justify; ">The most popular therapy was amputation, which was followed by rehabilitation. Amputation was avoided in 17 of the 21 patients who tried bone marrow cell treatment. Overall, in Northeast India, smoking, diabetes, and alcohol use were found to be independent risk factors for PVD that were specific to a given location.</p><p style="text-align: justify; ">Source:</p><p style="text-align: justify; ">Hajong, R., Rabha, P., Medhi, B. B., Sharma, S., Pai, P. S., Baruah, A. J., &amp; Devi, K. M. (2025). A retrospective risk-factor analysis of patients presenting with peripheral vascular disease in a tertiary care hospital in North-East India. Cureus.<a href="https://www.cureus.com/articles/356156-a-retrospective-risk-factor-analysis-of-patients-presenting-with-peripheral-vascular-disease-in-a-tertiary-care-hospital-in-north-east-india#!/" rel="nofollow"> https://doi.org/10.7759/cureus.82661</a></p>

371. Sound Wave Therapy Targets Amygdala to Relieve Depression, Anxiety, and PTSD Symptoms: Study Shows

     Wed, 30 Apr 2025 03:00:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285006-mdtv-2025-04-30t123557817.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">New research from Dell Medical School at The University of Texas at Austin introduces a groundbreaking treatment for patients suffering from <a href="https://medicaldialogues.in/topics/depression">depression</a>, <a href="https://medicaldialogues.in/topics/anxiety">anxiety</a>, and <a href="https://medicaldialogues.in/topics/trauma">trauma</a>-related disorders. The study, published in <i><a href="https://medicaldialogues.in/topics/Molecular-Psychiatry">Molecular Psychiatry</a></i>, explores the use of low-intensity focused ultrasound technology to safely and effectively modulate deep brain activity. This approach targets the amygdala, the brain region known for its role in mood and anxiety disorders, without the need for surgery or invasive procedures.</div><div style="text-align: justify;">In a double-blind study, 29 patients with various mood and anxiety disorders underwent MRI-guided focused ultrasound treatment on the left amygdala. After three weeks of daily treatments, participants showed significant improvements across a range of symptoms, including depression, anxiety, and PTSD. “This is the first time we’ve been able to directly modulate deep brain activity without invasive procedures or medications,” said Gregory Fonzo, Ph.D., the study's senior author.</div><div style="text-align: justify;">The treatment, which was well tolerated with no serious adverse events, reduced amygdala activity both immediately and over the course of the treatment period. This offers new hope for patients who haven’t responded to traditional therapies. Researchers are optimistic about the safety and efficacy of this non-invasive approach and are planning larger clinical trials.</div><div style="text-align: justify;">References: Barksdale, B. R., et al. (2025). Low-intensity transcranial focused ultrasound amygdala neuromodulation: a double-blind sham-controlled target engagement study and unblinded single-arm clinical trial. Molecular Psychiatry. doi.org/10.1038/s41380-025-03033-w.</div><div></div></div>

372. Study Identifies 56 Risk Factors That Could Prevent 63 Percent of Sudden Cardiac Arrest Cases

     Wed, 30 Apr 2025 02:45:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/285003-mdtv-2025-04-30t122615801.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">A new study published in the<i><a href="https://medicaldialogues.in/topics/Canadian-Journal-of-Cardiology"> Canadian Journal of Cardiology</a></i> reveals that 56 non-clinical risk factors, including lifestyle, physical measures, psychosocial factors, and environmental influences, could help prevent up to 63% of sudden <a href="https://medicaldialogues.in/topics/cardiac-arrest">cardiac arrest</a> (SCA) cases. SCA, a leading cause of death worldwide, claims about 60,000 lives annually in Canada alone. The study's lead author, Huihuan Luo, PhD, of Fudan University, emphasizes that improving modifiable risk factors, especially lifestyle habits, can significantly reduce SCA risk.</div><div style="text-align: justify;">Using an exposome-wide association study combined with Mendelian randomization, the research uncovered surprising findings. It found that eliminating the worst 40%–63% of risk factors, particularly lifestyle-related ones, could prevent a substantial portion of SCA cases. Factors like positive mood, weight management, <a href="https://medicaldialogues.in/topics/blood-pressure">blood pressure</a> control, and even moderate champagne or white wine consumption emerged as protective elements. "Surprisingly, higher consumption of champagne and white wine showed a cardioprotective effect, challenging the notion that only red wine offers these benefits," said Nicholas Grubic, MSc, and Dakota Gustafson, PhD, in the accompanying editorial.</div><div style="text-align: justify;">The study also revealed an inverse relationship between computer use and SCA risk, though further analysis clarified that this likely reflects socioeconomic or occupational differences rather than a direct protective effect.</div><div style="text-align: justify;">The researchers stress the importance of transitioning from reactive to preventive strategies to reduce the SCA burden, particularly in resource-limited settings. Identifying and targeting modifiable factors could lead to significant improvements in public health outcomes.</div><div style="text-align: justify;">References: Establishment and Validation of Prediction Models for Non-curative Resection After ESD for Early Gastric Cancer</div><div></div></div>

373. Study Links Rising Prediabetes in Youth to Increased Heart Risks and Early Cardiovascular Damage

     Wed, 30 Apr 2025 02:30:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/30/284998-mdtv-2025-04-30t122030553.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">A groundbreaking study from the University of Bristol's Children of the 90s cohort has revealed alarming trends in the health of <a href="https://medicaldialogues.in/topics/adolescents">adolescents</a> transitioning to young adulthood. The study tracked 1,595 participants from age 17 to 24, assessing the prevalence of <a href="https://medicaldialogues.in/topics/prediabetes">prediabetes </a>and its effects on heart health. Using two different <a href="https://medicaldialogues.in/topics/fasting">fasting </a>blood glucose cutpoints (≥5.6 mmol/L and ≥6.1 mmol/L), researchers found a significant increase in prediabetes, with 6.2% of 17-year-olds exhibiting fasting <a href="https://medicaldialogues.in/topics/blood-sugar">blood sugar</a> ≥5.6 mmol/L, rising to 26.9% by age 24.</div><div style="text-align: justify;">The study also noted a threefold increase in the prevalence of left ventricular hypertrophy (LVH) from 2.4% at age 17 to 7.1% at 24. "Even healthy-looking adolescents may be on a path toward cardiovascular diseases due to high blood glucose and insulin resistance," said Andrew Agbaje, associate professor at the University of Eastern Finland.</div><div style="text-align: justify;">The findings highlight a troubling link between persistently high blood glucose and heart dysfunction, particularly in females, where the damage to heart function occurred five times faster than in males. Insulin resistance was also associated with a 10% increased risk of premature heart damage. The study underscores the importance of early intervention and lifestyle changes, especially as adolescents gain independence from family influences.</div><div style="text-align: justify;">This research, the largest of its kind, stresses the critical need for awareness and prevention of cardiometabolic diseases in youth, particularly in light of the rising prevalence of prediabetes.</div><div style="text-align: justify;">Reference: Agbaje, A. O., et al. (2025) Persistent Hyperglycemia and Insulin Resistance with the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care. doi.org/10.2337/dc24-2459.</div><div></div></div>

374. Antenatal care Contacts beyond 4 to 7 years fails to enhance immediate or exclusive breastfeeding rates: Study

     Tue, 29 Apr 2025 15:30:53 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/03/03/203742-breastfeeding-tips720x432.webp' /><p style="text-align: justify; ">Recent study investigates breastfeeding practices in sub-Saharan Africa following the 2016 World Health Organization (WHO) antenatal care (ANC) policy update, which recommends a minimum of eight ANC contacts during pregnancy. It examines trends in immediate and exclusive breastfeeding (IEBF) and explores the relationship between ANC uptake (specifically comparing 4-7 contacts versus 8+ contacts) and breastfeeding practices.</p><p style="text-align: justify; ">Analysis of DHS Data in Sub-Saharan Africa</p><p style="text-align: justify;">Data from Demographic and Health Surveys (DHS) conducted between 2018 and 2023 across 19 sub-Saharan African countries were analyzed. The analysis included 25,669 individuals and focused on immediate breastfeeding (IBF), defined as breastfeeding within one hour of birth, and exclusive breastfeeding (EBF) for infants aged zero to six months. Several health service, clinical, social and contextual factors available in DHS surveys for eligible countries were also considered.</p><p style="text-align: justify;">Variations in Breastfeeding Rates Across Countries</p><p style="text-align: justify;">The study found substantial variations in breastfeeding rates across countries. IBF ranged from 24.4% in Senegal to 86.7% in Rwanda, while EBF ranged from 17.6% in Gabon to 74.2% in Kenya. Most countries' IBF rates were higher than EBF rates. Only a small fraction of women, 8.6% on average, reported attending eight or more ANC contacts.</p><p style="text-align: justify;">Association Between ANC Contacts and Breastfeeding Practices</p><p style="text-align: justify;">Pooled analysis across all countries showed that having 8+ ANC contacts, compared to 4-7 contacts, was not significantly associated with either IBF or EBF. However, results did indicate that there was a relationship between health service, clinical, demographic, and contextual factors and IBF and EBF.</p><p style="text-align: justify;">Implications for Promoting Optimal Breastfeeding Practices</p><p style="text-align: justify;">The findings suggest limited additional benefits of 8+ ANC contacts over 4-7 contacts in promoting IEBF, despite the WHO's recommendation. It emphasizes the need for comprehensive strategies to promote ANC uptake and improve the quality of ANC contacts through behavior change interventions and complementary health service delivery. The results highlight the need to focus on improved quality of care, tailored interventions, and addressing misconceptions to improve both ANC attendance and breastfeeding outcomes in sub-Saharan Africa.</p><p style="text-align: justify;">Key Points</p><p style="text-align: justify;">* The study analyzes data from Demographic and Health Surveys (DHS) conducted between 2018 and 2023 in 19 sub-Saharan African countries, involving 25,669 individuals, to assess breastfeeding practices following the 2016 WHO antenatal care (ANC) policy update.</p><p style="text-align: justify;">\* Immediate breastfeeding (IBF) rates varied significantly across countries, ranging from 24.4% in Senegal to 86.7% in Rwanda, while exclusive breastfeeding (EBF) rates ranged from 17.6% in Gabon to 74.2% in Kenya.</p><p style="text-align: justify;">\* Across the surveyed countries, a small percentage of women (8.6% on average) reported attending eight or more ANC contacts, as recommended by the WHO.</p><p style="text-align: justify;">\* Pooled analysis revealed that attending 8+ ANC contacts, compared to 4-7 contacts, did not show a significant association with either immediate or exclusive breastfeeding practices.</p><p style="text-align: justify;">\* Health service, clinical, demographic, and contextual factors were found to have a relationship with immediate breastfeeding and exclusive breastfeeding practices.</p><p style="text-align: justify;">\* The findings suggest that increasing ANC contacts beyond 4-7 may not significantly improve immediate and exclusive breastfeeding rates, highlighting the importance of comprehensive strategies focusing on the quality of ANC contacts, behavior change interventions, and complementary health service delivery.</p><p style="text-align: justify;">Reference –</p><p style="text-align: justify;">Bolanle Olapeju et al. (2025). Antenatal Care And Breastfeeding Practices In Sub-Saharan Africa: An Analysis Of Demographic And Health Surveys. *BMC Pregnancy And Childbirth*, 25. https://doi.org/10.1186/s12884-025-07188-w.</p>

375. Study Finds TD/PV Ratio Boosts Prostate Cancer Detection When Combined with PI-RADS

     Tue, 29 Apr 2025 15:30:27 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/17/283356-prostate-biopsy.webp' /><p style="text-align: justify; "><strong>Japan</strong>: A recent retrospective analysis has highlighted the tumor diameter-to-prostate volume ratio (TD/PV) as an effective predictive marker for <a href="https://medicaldialogues.in/topics/prostate--cancer">prostate cancer (PCa)</a> and clinically significant prostate cancer (csPCa) in men undergoing <a href="https://medicaldialogues.in/topics/mri">MRI</a>/transrectal ultrasound (MRI/TRUS) fusion-targeted <a href="https://medicaldialogues.in/topics/biopsies">biopsies</a>.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Published in <em>Urologic Oncology: Seminars and Original Investigations</em>, the study demonstrated that incorporating TD/PV into the biopsy process enhanced prediction accuracy, surpassing traditional markers. Additionally, when combined with the prostate imaging-reporting and data system (PI-RADS), TD/PV further improved prediction accuracy, achieving AUC values of 0.861 and 0.845 for PCa and csPCa, respectively.</p><p style="text-align: justify; ">MRI, alongside PI-RADS and MRI/TRUS fusion-targeted biopsy, has significantly improved the accuracy of prostate cancer diagnosis. However, some suspected PCa lesions in PI-RADS categories 3 and 4 remain undiagnosed, pointing to the need for further refinement of diagnostic methods. The researchers suggest that the accuracy of MRI/TRUS fusion-targeted biopsy can be improved by incorporating lesion size and prostate volume (PV) into the PI-RADS evaluation.</p><p style="text-align: justify; ">To explore this, Shunsuke Miyamoto and colleagues from the Department of Urology at Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan, investigated how the TD/PV ratio could enhance the prediction of PCa and csPCa in PI-RADS categories 3–5 lesions. They also aimed to develop predictive nomograms that combined TD/PV and PI-RADS.</p><p style="text-align: justify; ">The researchers reviewed data from patients who underwent MRI/TRUS fusion-targeted biopsy for PI-RADS 2.1 categories 3–5 lesions between 2017 and 2023. TD/PV was calculated by dividing tumor diameter by total prostate volume, with csPCa defined as a Gleason score of ≥ 3+4. The predictive nomograms for PCa and csPCa were created using univariable and multivariable logistic regression. Their accuracy was evaluated using receiver operating characteristic (ROC) curves and the area under the curve (AUC).</p><p style="text-align: justify; ">Key findings from the study included:</p><ul><li style="text-align: justify; ">A total of 565 patients were analyzed.</li><li style="text-align: justify; ">The AUC of TD/PV was significantly higher than that of PSA, tumor diameter, PSA density, and PI-RADS for predicting PCa (AUC: 0.840) and csPCa (AUC: 0.819).</li><li style="text-align: justify; ">Multivariable analyses confirmed TD/PV as a significant predictive factor for both PCa and csPCa in MRI/TRUS fusion-targeted biopsy.</li><li style="text-align: justify; ">Predictive nomograms combining TD/PV and PI-RADS were developed, with AUCs for PCa and csPCa predictions being 0.861 and 0.845, respectively.</li></ul><p style="text-align: justify; ">"In the retrospective analysis, the combination of TD/PV and PI-RADS category significantly improved the prediction of PCa and csPCa in MRI/TRUS fusion-targeted biopsy, particularly for PI-RADS categories 3 and 4 lesions," the authors noted. "The predictive nomograms integrating TD/PV with PI-RADS provided a more accurate prediction of PCa and csPCa diagnoses."</p><p style="text-align: justify; ">They concluded, "These findings offer valuable insights for physicians, aiding in better decision-making regarding the indications for MRI/TRUS fusion-targeted biopsy."</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Kohada, Y., Miyamoto, S., Hayashi, T., Tasaka, R., Honda, Y., Ishikawa, A., Kobatake, K., Sekino, Y., Kitano, H., Goto, K., Ikeda, K., Goriki, A., Hieda, K., Kitamura, N., Awai, K., &amp; Hinata, N. (2025). Utility of tumor diameter-to-prostate volume ratio for predicting the outcome of magnetic resonance imaging/transrectal ultrasound fusion-targeted biopsy. Urologic Oncology: Seminars and Original Investigations. https://doi.org/10.1016/j.urolonc.2025.03.021</p></div><p style="text-align: justify; "><br></p>

376. Twice-Weekly and Thrice-Weekly Hemodialysis have Comparative Survival Outcomes: Study

     Tue, 29 Apr 2025 15:15:55 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/19/232503-hemodialysis-50.webp' /><p style="text-align: justify; ">Researchers have found in a new study that Patients undergoing twice-weekly hemodialysis demonstrated comparable overall survival at two years when compared to those on a thrice-weekly schedule. While a twice-weekly regimen may serve as a viable option during the initial year of dialysis—particularly in resource-limited settings—it poses potential risks that require vigilant monitoring beyond the first year.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">The optimal frequency of maintenance hemodialysis remains a subject of debate. In many countries, twice-weekly hemodialysis is still commonly practiced. This trial aimed to compare the outcomes of patients undergoing twice-weekly versus thrice-weekly hemodialysis.</p><p dir="ltr" style="text-align: justify; ">This prospective, multicenter, nonrandomized trial included incident adult patients, with chronic kidney disease stage 5, initiating hemodialysis between January 2018 and August 2021. Patients were allocated to either a twice-weekly or thrice-weekly regimen, and monitored at 1, 3, 6, 12 and 24 months. This trial was terminated before reaching the required sample size due to the COVID-19 pandemic and economic factors. Recruitment achieved 25% of the projected number. Missing baseline factors were imputed using multiple imputation algorithms, then entered in a logistic regression model to estimate propensity scores. </p><p dir="ltr" style="text-align: justify; ">The primary outcome was two-year survival analyzed using a Cox regression survival model adjusted for propensity scores and baseline residual urine output. Secondary outcomes included hospitalization rates, uncontrolled hypertension and cumulative erythropoietin dose at two years, analyzed using regression models adjusted for propensity scores and baseline residual urine output. All analyses were conducted on an intention-to-treat basis. </p><p dir="ltr" style="text-align: justify; ">Results: A total of 132 patients on thrice-weekly hemodialysis and 71 on twice-weekly hemodialysis were included. The mean age was 67 ± 15 years and the median eGFR at dialysis initiation was 6 (4,8) mL/min/1.73 m2. At one year, patients in the twice-weekly group had greater residual urine output. At two years, there was no significant difference in survival (HR = 0.84; 95% CI: 0.37, 1.90), hospitalization rates (P = 0.515) or uncontrolled hypertension (P = 0.442). The twice-weekly group showed a trend toward higher erythropoietin requirements (P = 0.08). Serum potassium levels and the number of antihypertensive medications were greater in the twice-weekly group. Patients on twice-weekly hemodialysis showed comparable overall survival at two years to those on thrice-weekly hemodialysis. While a twice-weekly regimen may be a viable option during the first year of dialysis, especially in low-resource settings, it carries potential risks that necessitate careful monitoring after the first year.</p><div style="text-align: justify;"></div><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Aoun, M., Finianos, S., Beaini, C. et al. Twice against thrice-weekly hemodialysis (TATH): a multicenter nonrandomized trial. BMC Nephrol 26, 176 (2025). https://doi.org/10.1186/s12882-025-04105-3</p><div style="text-align: justify;"></div><div style="text-align: justify;"></div></div>

377. In Pediatric Cardiac Surgery video Laryngoscopy for TEE Probe Insertion safe with higher first attempt success rate: Study

     Tue, 29 Apr 2025 15:00:59 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/02/25/203195-transesophageal-echocardiography.webp' /><p style="text-align: justify; ">Recent randomized controlled study compared the use of video laryngoscopy (VL) versus the conventional blind technique for inserting the transoesophageal echocardiography (TEE) probe in 100 pediatric patients (aged 2-10 years) undergoing cardiac surgery. The primary outcome was the incidence of oropharyngeal injury, while the secondary outcomes were the number of insertion attempts, duration of successful insertion, and the relationship between the laryngeal and oesophageal inlet.</p><p style="text-align: justify;">Patient Randomization and Procedures</p><p style="text-align: justify;">Patients were randomized into two groups - the conventional group (Group C, n=50) where the TEE probe was inserted using the blind technique, and the VL group (Group VL, n=50) where VL was used to insert the probe. All patients underwent VL examination after TEE probe removal to assess for oropharyngeal injury. The results showed that the incidence of pharyngeal mucosal injury was significantly lower in Group VL (n=2, 4%) compared to Group C (n=9, 18%, p=0.025). The number of attempts for successful TEE probe insertion was also significantly lower in Group VL (p&lt;0.05). The mean duration for successful insertion on the first attempt was significantly longer in Group VL (28.75±7.65 seconds) compared to Group C (18.55±5.0 seconds, p&lt;0.0001). In Group VL, the oesophageal inlet was found to be posterior in 86% of patients and posterolateral in 14% relative to the laryngeal inlet.</p><p style="text-align: justify;">Conclusion and Recommendations</p><p style="text-align: justify;">The authors concluded that using VL for TEE probe insertion in pediatric cardiac surgery patients significantly reduced the incidence of pharyngeal injury and provided direct visualization of the oesophageal inlet, leading to a higher first-attempt success rate compared to the conventional blind technique. They recommended regular use of VL for TEE probe insertion in this patient population.</p><p style="text-align: justify;">Key Points</p><p style="text-align: justify;">1. This randomized controlled study compared the use of video laryngoscopy (VL) versus the conventional blind technique for inserting the transoesophageal echocardiography (TEE) probe in 100 pediatric patients (aged 2-10 years) undergoing cardiac surgery.</p><p style="text-align: justify;">2. The primary outcome was the incidence of oropharyngeal injury, while the secondary outcomes were the number of insertion attempts, duration of successful insertion, and the relationship between the laryngeal and oesophageal inlet.</p><p style="text-align: justify;">3. Patients were randomized into two groups - the conventional group (Group C, n=50) where the TEE probe was inserted using the blind technique, and the VL group (Group VL, n=50) where VL was used to insert the probe. All patients underwent VL examination after TEE probe removal to assess for oropharyngeal injury.</p><p style="text-align: justify;">4. The incidence of pharyngeal mucosal injury was significantly lower in Group VL (n=2, 4%) compared to Group C (n=9, 18%, p=0.025). The number of attempts for successful TEE probe insertion was also significantly lower in Group VL (p&lt;0.05). The mean duration for successful insertion on the first attempt was significantly longer in Group VL (28.75±7.65 seconds) compared to Group C (18.55±5.0 seconds, p&lt;0.0001).</p><p style="text-align: justify;">5. In Group VL, the oesophageal inlet was found to be posterior in 86% of patients and posterolateral in 14% relative to the laryngeal inlet.</p><p style="text-align: justify;">6. The authors concluded that using VL for TEE probe insertion in pediatric cardiac surgery patients significantly reduced the incidence of pharyngeal injury and provided direct visualization of the oesophageal inlet, leading to a higher first-attempt success rate compared to the conventional blind technique. They recommended regular use of VL for TEE probe insertion in this patient population.</p><p style="text-align: justify;">Reference –</p><p style="text-align: justify;">Guriqbal Singh et al. (2025). A Randomised Controlled Trial Comparing Video Laryngoscopy Versus Conventional Blind Technique For Transoesophageal Echocardiography Probe Insertion In Paediatric Patients Undergoing Cardiac Surgery: A Pilot Study. *Indian Journal Of Anaesthesia*. https://doi.org/10.4103/ija.ija_975_24</p>

378. Persistent organic pollutants are associated with higher BP in teenagers after weight loss surgery: Study

     Tue, 29 Apr 2025 15:00:19 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/06/231630-blood-pressure-50.webp' /><p style="text-align: justify; ">Researchers from the Keck School of Medicine of USC have found that persistent organic pollutants (POPs)-synthetic toxic chemicals often found in food sources and stored in body fat-are associated with long term higher <a href="https://medicaldialogues.in/topics/blood-pressure">blood pressure</a> in adolescents who have undergone <a href="https://medicaldialogues.in/topics/bariatric-surgery">bariatric surgery</a>, a weight-loss intervention. </p><p style="text-align: justify; ">The study, funded by the National Institutes of Health and published in the ACS journal <i>Environmental Science &amp; Technology</i>, suggested that POPs diminished the beneficial effect of bariatric surgery on improved blood pressure due to disruptions in lipid metabolism, which is how the body processes fat. The researchers also identified a plausible biological pathway explaining the relationship between POPs and changes in blood pressure. </p><p style="text-align: justify;">These findings could eventually lead to treatments to reduce adverse health effects of exposure to these environmental chemicals on individuals with <a href="https://medicaldialogues.in/topics/obesity">obesity</a>, particularly for those pursuing weight-loss interventions such as bariatric surgery. </p><p style="text-align: justify; ">“While bariatric surgery is an effective treatment used to address severe obesity and improve cardiometabolic health, it also releases POPs stored in fat into the bloodstream,” says Shudi Pan, the study’s first author and a fourth year PhD candidate in the Department of Population and Public Health Sciences at Keck School of Medicine of USC. </p><p style="text-align: justify;">Although their toxicity led many countries to start restricting the use of POPS more than 20 years ago, they remain a global health challenge since they persist for long periods in the environment. They have been detected at concerning levels worldwide even in regions where these chemicals were never manufactured or used. </p><p style="text-align: justify;">“POPs are considered an emerging risk factor for <a href="https://medicaldialogues.in/topics/hypertension">hypertension</a> and our study provided us a unique opportunity to evaluate the relationship between POPs exposure and blood pressure. Until now, few studies have examined how POPs exposures in adipose tissue affect blood pressure,” says Pan. “Similarly, the mechanisms underlying the relationship between POP mixtures and blood pressure have been unclear.” </p><p style="text-align: justify;">The study included data from 57 adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) consortium, who underwent bariatric surgery. </p><p style="text-align: justify;">“We measured the level of POPs stored in adipose tissue before surgery. After, we assessed whether it affected blood pressure in the short term—at 6 months, and then five years after surgery,” says Pan. </p><p style="text-align: justify;">Pan’s research found that POPs mixtures were linked to higher systolic blood pressure five years after bariatric surgery. Additionally, the researchers incorporated metabolomics to understand the underlying mechanisms of POP mixtures in adipose tissue on changes in blood pressure. Metabolomics refers to the study of metabolites which are small molecules or substances made when the body breaks down food, chemicals, or its own tissue—in this case the breakdown of body fat after bariatric surgery. </p><p style="text-align: justify;">“Through a technique called high-resolution mass spectrometry, we assessed these metabolites, thousands at a time, to determine what complex biological changes were occurring that led to changes in blood pressure,” says Pan. </p><p style="text-align: justify;">The researchers’ analysis revealed that one particular pathway involved in the production of prostaglandin was key in influencing blood pressure changes in the long-term, making this one of the first studies to identify a plausible rationale. Prostaglandin has long been proved to be involved in blood pressure regulation, and this study found that POPs modified prostaglandin pathways, contributing to disruptions in blood pressure regulations. </p><p style="text-align: justify;">“While our study had a small sample size, we think the prostaglandin pathway is a key player in understanding the biological mechanism between POPs and the development of high blood pressure in this demographic and more research is needed to further understand this particular pathway linking POP exposures to blood pressure regulation,” says Pan. </p><p style="text-align: justify; ">High blood pressure in adolescence is associated with an increased risk of cardiovascular disease and cardiovascular diseases mortality in adulthood. Interventions that can address early life hypertension can help reduce the risk of cardiovascular disease, which remains a leading cause of death worldwide.&nbsp;</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Shudi PanZhenjiang Li*Douglas I. WalkerBrittney O. BaumertHongxu WangJesse A. Goodrich, Metabolic Signatures in Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures to Blood Pressure Five Years After Bariatric Surgery Among Adolescents, Environmental Science &amp; Technology, DOI:10.1021/acs.est.4c13902.&nbsp;</p>

379. Almost half of children with complicated appendicitis can recover from surgery at home: Study

     Tue, 29 Apr 2025 15:00:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/11/27/262483-appendicitis-50.webp' /><p style="text-align: justify; ">Almost half of children who require surgery for complicated<a href="https://medicaldialogues.in/topics/appendicitis"> appendicitis </a>can safely complete their recovery at home, according to a new study. </p><p style="text-align: justify;">The research, led by Murdoch Children’s Research Institute (MCRI) and published in the <i>Journal of Pediatric Surgery</i>, found more than 40 per cent who received care in the home following a complex appendectomy recovered faster and had fewer complications. </p><p style="text-align: justify;">More than 300 patients present with appendicitis to The Royal Children's Hospital (RCH) every year, with about one in three experiencing a burst appendix or severe infection. </p><p style="text-align: justify;">The study involved 83 children, aged five to 18 years, admitted to the RCH for a complicated appendicectomy, with 35 suitable for the Hospital in the Home (HITH) program. All patients needed at least five days of intravenous <a href="https://medicaldialogues.in/topics/antibiotics">antibiotics</a> (IV) post-surgery. Under the program, a nurse visited the child’s home daily to administer the antibiotics and record clinical observations. </p><p style="text-align: justify;">MCRI Associate Professor Penelope Bryant said under this model, patients at home recovered more quickly and didn’t require readmission to hospital. </p><p style="text-align: justify;">“Acute post-operative care at home is rare, but we found it’s possible for children to spend 35 per cent less time in hospital after complicated surgery,” she said. This could be done safely and without prolonging IV courses or broadening antibiotic use. </p><p style="text-align: justify;">“These findings will help clinicians to identify which children are suitable for HITH care following surgery for complicated appendicitis.” </p><p style="text-align: justify;">MCRI Associate Professor Warwick Teague said the HITH program, used heavily during the COVID-19 pandemic, had the added benefits of reduced hospital and family costs, improved quality of life, less time taken from work and prevention of hospital-acquired infections. </p><p style="text-align: justify;">“The pandemic presented us with the need and opportunity to deliver care to children in their home,” he said. This study showed even children who had severe appendicitis can be well cared for at home after surgery, freeing up hospital beds for other sick children and those needing surgery. </p><p style="text-align: justify;">“Traditionally after surgery for severe appendicitis, surgeons have insisted on daily reviews in hospital by the surgical team. However, in this study we learnt that optimal postoperative care be delivered at home, by well-trained non-surgical clinicians working as a team with surgeons.” </p><p style="text-align: justify; ">“For complicated appendicitis, the HITH program also saved over $1,400 per day for the hospital and $300 daily for families, reducing cost-of-living pressures with longer-term benefits for healthcare sustainability.”</p><p style="text-align: justify;">Reference:</p><p style="text-align: justify; ">Ling Chen, Sebastian K. King, Misel Trajanovska, Lynda M. Gaynor, Veronica Cerratti, Rosemary Burgess, Gregory J.G. Nolan, Warwick J. Teague, Penelope A. Bryant, Getting children home sooner on intravenous antibiotics with a Hospital-in-the-Home model of care for complicated appendicitis, Journal of Pediatric Surgery Open, 2025,https://doi.org/10.1016/j.yjpso.2025.100196.</p>

380. Bubbly idea: Ultrafine bubble showers suppress atopic dermatitis

     Tue, 29 Apr 2025 15:00:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/03/11/234011-atopic-dermatitis-50.webp' /><p style="text-align: justify; ">Bubble baths might be soothing soaks, but bubble showers could be the next thing in keeping the skin clean. </p><p style="text-align: justify;">An Osaka Metropolitan University-led medical research team found that ultrafine bubble showers might help prevent <a href="https://medicaldialogues.in/topics/atopic-dermatitis">atopic dermatitis</a>. </p><p style="text-align: justify;">Graduate School of Medicine student Ayaki Matsumoto and Associate Professor Hisayoshi Imanishi led the study into using ultrafine bubbles, often used to clean medical equipment, on mice with atopic dermatitis. </p><p style="text-align: justify; ">The scientists found that in mice with atopic dermatitis due to external factors, inflammation was markedly suppressed when the affected skin was showered with ultrafine bubbles, while normal showers also showed some positive results. Additionally, the ultrafine bubble showers improved the levels of proteins in the skin that act as a protective barrier. For mice with atopic dermatitis caused by genetic factors, however, there were no significant differences even compared to mice who were not showered. </p><p style="text-align: justify;">“The results of this study suggest that ultrafine bubble shower treatment might be a new treatment for allergen-induced atopic dermatitis for humans, but this study was conducted on mice and the shower treatment period was short, only a week or two,” stated graduate student Matsumoto. </p><p style="text-align: justify;">“From now on,” Professor Imanishi added, “it will be necessary to conduct ultrafine bubble shower therapy for several months on human patients to examine the effects.”</p><p style="text-align: justify;">Reference:</p><p style="text-align: justify;">Ayaki Matsumoto, Beneficial effects of ultrafine bubble shower on a mouse model of atopic dermatitis, Frontiers in Immunology, https://doi.org/10.3389/fimmu.2024.1483000.</p>

381. Subarachnoid spinal anesthesia Safe and Effective Anesthesia Option for High-Risk Obstetric Cases: Study

     Tue, 29 Apr 2025 15:00:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2021/04/16/151321-spinal-anesthesia.webp' /><p style="text-align: justify; ">Recent study discusses the challenges of managing parturients with cardiovascular disease (CVD) during anesthesia, highlighting the increased perioperative morbidity and mortality due to the heightened demands of pregnancy. The preference for regional anesthesia in obstetrics is established, with general anesthesia (GA) and conventional spinal posing risks of hemodynamic instability in CVD patients. The introduction of segmental spinal anesthesia (SSA) has shown promise in providing better hemodynamic stability by confining anesthesia to specific dermatomes, enhancing safety for high-risk patients.</p><p style="text-align: justify; ">Case Studies of Parturients with Pre-Existing Cardiovascular Disease</p><p style="text-align: justify; ">The research presented five cases of parturients with significant pre-existing CVD (severe mitral stenosis, aortic stenosis, hypertrophic obstructive cardiomyopathy, and peripartum cardiomyopathy) who successfully underwent cesarean section under SSA at a particular institute from September 2023 to January 2024. The implementation of thorough preoperative evaluation and optimization was emphasized, with a multidisciplinary approach for planning combined epidural and SSA, invasive monitoring, and postoperative intensive care unit (ICU) management. Informed consent and meticulous monitoring were highlighted throughout the procedures.</p><p style="text-align: justify; ">Anesthetic Technique Employed for Parturients with CVD</p><p style="text-align: justify; ">The anesthetic technique employed included segmental spinal administration at specific vertebra levels using a combination of bupivacaine and fentanyl to achieve effective blockade and hemodynamic stability. Close monitoring and prompt management of hypotensive episodes with phenylephrine boluses were reported. Postoperative care included ongoing vigilance, epidural analgesia, cardiac function reassessment, and uneventful recovery for all cases.</p><p style="text-align: justify; ">Discussion on Anesthesia Options for CVD Patients</p><p style="text-align: justify; ">Different options for anesthesia were discussed, including graded epidural, combined spinal-epidural, and continuous spinal anesthesia, with a preference for SSA due to its muscle relaxation, reduced anesthetic requirement, and stable hemodynamics. The study emphasized the potential risks of GA in CVD patients, suggesting carefully managed GA might be necessary in specific scenarios to ensure patient safety. The findings advocate for SSA as an effective, safe, and viable alternative anesthesia technique for high-risk obstetric cases involving parturients with underlying CVD. The research exhibited successful outcomes, underlining the importance of individualized approaches and meticulous perioperative management to enhance safety and optimize recovery in such complex clinical scenarios.</p><p style="text-align: justify; ">Key Points</p><p style="text-align: justify;">- Regional anesthesia, especially segmental spinal anesthesia (SSA), is preferred over general anesthesia (GA) in managing parturients with cardiovascular disease (CVD) due to the risks of hemodynamic instability associated with GA and conventional spinal anesthesia.</p><p style="text-align: justify;">- Five cases of parturients with significant pre-existing CVD successfully underwent cesarean section under SSA, emphasizing the importance of thorough preoperative evaluation, multidisciplinary planning, invasive monitoring, and postoperative intensive care unit (ICU) management to ensure patient safety.</p><p style="text-align: justify;">- The anesthetic technique employed involved segmental spinal administration at specific vertebra levels using a combination of medications to achieve effective blockade and stable hemodynamics, with close monitoring and prompt management of hypotensive episodes.</p><p style="text-align: justify;">- Different anesthesia options, including graded epidural, combined spinal-epidural, and continuous spinal anesthesia, were discussed, with a preference for SSA due to its muscle relaxation, reduced anesthetic requirement, and stable hemodynamics, highlighting the potential risks of GA in CVD patients.</p><p style="text-align: justify;">- The study advocates for SSA as an effective, safe, and viable alternative anesthesia technique for high-risk obstetric cases involving parturients with underlying CVD, stressing the importance of individualized approaches and meticulous perioperative management to enhance safety and optimize recovery in complex clinical scenarios.</p><p style="text-align: justify;">- Successful outcomes were achieved with the use of SSA, underscoring the significance of personalized care and detailed perioperative management in improving safety and recovery for parturients with CVD undergoing anesthesia for cesarean sections.</p><p style="text-align: justify;">Reference –</p><p style="text-align: justify;">Ajit Kumar et al. (2025). Enhancing Recovery In Cervical Spine Surgery With Erector Spinae Plane (ESP) Block- A Case Series. *Indian Journal Of Anaesthesia*. https://doi.org/10.4103/ija.ija_690_24.</p>

382. Osteoporosis cases on the rise but risk differs across demographics, reveals study

     Tue, 29 Apr 2025 14:45:46 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/02/11/273655-osteoporosis-50.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">While increased average life expectancy is a testament to modern medicine and public health efforts, an aging population comes with an increased presence of chronic diseases such as <a href="https://medicaldialogues.in/topics/osteoporosis">osteoporosis</a>. Research published in <em>Osteoporosis International</em> by Hong Xue&nbsp; and graduate students Christopher Naso, Ge Song, and Kenny Lin supplies evidence that some groups are at greater risk for osteoporosis and less likely to receive an official diagnosis:</p><p style="text-align: justify; ">• From 2005 to 2018, there has been a significant increase in the overall number of individuals who have osteoporosis in the U.S.</p><p style="text-align: justify; ">• Osteoporosis has increased across all age groups, except those 80 years and older.</p><p style="text-align: justify; ">• Non-Hispanic White women were shown to have the highest prevalence of diagnosed osteoporosis.</p><p style="text-align: justify; "><span>•&nbsp;</span>Nearly 70% of individuals with osteoporosis have gone undiagnosed, primarily men, Mexican Americans, and individuals aged 50-59.</p><p style="text-align: justify; ">This study is the first to assess undiagnosed osteoporosis trends over time across by gender, ethnicity/race, age group, and both gender and ethnicity/race. Findings indicate there is greater need for proactive care for <a href="https://medicaldialogues.in/topics/bone-health">bone health</a>.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Naso, C.M., Lin, SY., Song, G. et al. Time trend analysis of osteoporosis prevalence among adults 50 years of age and older in the USA, 2005–2018. Osteoporos Int 36, 547–554 (2025). https://doi.org/10.1007/s00198-025-07395-3</p></div>

383. Weight training protects older people's brains against dementia, study suggests

     Tue, 29 Apr 2025 14:45:40 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/12/278187-dementia-3.webp' /><p style="text-align: justify; ">The benefits of weight training are many: it promotes gains in strength and muscle mass, reduces body fat, and contributes to well-being and <a href="https://medicaldialogues.in/topics/mental%20health">mental health.</a> And now a study carried out at the State University of Campinas (UNICAMP), in the state of São Paulo, Brazil, has demonstrated another important effect: it protects the brains of older people against<a href="https://medicaldialogues.in/topics/dementia"> dementia</a>. The results were published in the journal <i>GeroScience</i>. </p><p style="text-align: justify;">The study involved 44 people with mild <a href="https://medicaldialogues.in/topics/cognitive-impairment">cognitive impairment </a>– an intermediate clinical condition between normal aging and <a href="https://medicaldialogues.in/topics/alzheimer%E2%80%99s-disease">Alzheimer’s disease</a> in which <a href="https://medicaldialogues.in/topics/cognitive-decline">cognitive decline</a> is greater than expected for age, indicating a higher risk of dementia. The results showed that strength training not only improved memory performance but also altered brain anatomy. </p><p style="text-align: justify; ">After six months of twice-weekly weight training, the participants showed protection against atrophy in the hippocampus and precuneus – brain areas associated with Alzheimer’s disease-as well as improvements in parameters that reflect the health of neurons (white matter integrity). </p><p style="text-align: justify;">“We already knew that there would be physical improvement. Cognitive improvement was also imagined, but we wanted to see the effect of weight training on the brains of older people with mild cognitive impairment. The study showed that, fortunately, weight training is a strong ally against dementia, even for people who are already at high risk of developing it,” says Isadora Ribeiro, a FAPESP doctoral fellowship recipient at UNICAMP’s School of Medical Sciences (FCM) and first author of the article. </p><p style="text-align: justify; ">The work was carried out within the framework of the Brazilian Institute for Neuroscience and Neurotechnology (BRAINN) – a FAPESP Research, Innovation and Dissemination Center (RIDC)-and is the first to demonstrate what happens to the integrity of the white matter of individuals with mild cognitive impairment after weight training. </p><p style="text-align: justify;">“As well as neuropsychological tests, we also performed MRI scans at the beginning and end of the study. These results are very important because they indicate the need to include more physical educators in the public health system at the primary health care level since increased muscle strength is associated with a reduced risk of dementia. It’s a less complex and cheaper treatment that can protect people from serious diseases,” comments Marcio Balthazar, BRAINN researcher and study supervisor. </p><p style="text-align: justify;">“For example, the new anti-amyloid drugs approved in the United States indicated for the treatment of dementia and for people with mild cognitive impairment, cost around USD 30,000 a year. That’s a very high cost. These non-pharmacological measures, as we’ve shown is the case with weight training, are effective, not only in preventing dementia but also in improving mild cognitive impairment,” the researcher adds. </p><h3 style="text-align: justify; ">Protocol </h3><p style="text-align: justify;">The research participants were divided into two groups: half underwent a resistance exercise program with weight training sessions twice a week, at moderate to high intensity and with progressive loads; the other half did not exercise during the study period and were part of the so-called control group. </p><p style="text-align: justify;">In the analyses carried out at the end of the intervention, the volunteers who practiced weight training had better performance in verbal episodic memory, improved integrity of neurons and areas related to Alzheimer’s disease protected from atrophy, while the control group showed a worsening of brain parameters. </p><p style="text-align: justify;">“A characteristic of people with mild cognitive impairment is that they have volume loss in some brain regions associated with the development of Alzheimer’s. But in the group that did strength training, the right side of the hippocampus and precuneus were protected from atrophy. This result justifies the importance of regular weight training, especially for older people,” Ribeiro highlights. </p><p style="text-align: justify;">The researcher believes that a longer period of training could lead to even more positive results than those reported in the study. “All the individuals in the bodybuilding group showed improvements in memory and brain anatomy. However, five of them reached the end of the study without a clinical diagnosis of mild cognitive impairment, such was their improvement. This leads us to imagine that longer training sessions, lasting three years, for example, could reverse this diagnosis or delay any kind of dementia progression. It’s certainly something to be hopeful about and something that needs to be studied in the future,” Ribeiro argues. </p><p style="text-align: justify;">According to the researchers, weight training can protect the brain against dementia on two fronts: by stimulating the production of neural growth factor (an important protein for the growth, maintenance and survival of neurons) and by promoting global disinflammation in the body. </p><p style="text-align: justify; ">“Any physical exercise, whether weight training or aerobic activity, is known to increase levels of a chemical involved in brain cell growth. It can also mobilize anti-inflammatory T-cells. This is key. After all, the more pro-inflammatory protein that is released in the body, the greater the chance of developing dementia, accelerating the neurodegenerative process and forming dysfunctional proteins that eventually kill neurons,” Balthazar explains. </p><p style="text-align: justify; ">To assess these issues, the volunteers’ levels of irisin and BDNF (brain-derived neurotrophic factor) – substances whose synthesis is stimulated by muscle contraction and which are associated with neural protection and synaptic plasticity-were measured. The results are currently being analyzed. </p><p style="text-align: justify; ">“It’s a continuation of this study in which we’ll try to better understand how these factors are related to changes in brain anatomy. We believe that it’s a set of anti-inflammatory and neuroprotective factors that lead to these changes,” Ribeiro predicts.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Ribeiro, I.C., Teixeira, C.V.L., de Resende, T.J.R. et al. Resistance training protects the hippocampus and precuneus against atrophy and benefits white matter integrity in older adults with mild cognitive impairment. GeroScience (2025). https://doi.org/10.1007/s11357-024-01483-8</p>

384. Pretreatment with chlorhexidine and benzalkonium chloride fails to impact Long-Term Bonding in immediate dentin sealing: Study

     Tue, 29 Apr 2025 14:45:39 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/03/18/205395-teeth-2.webp' /><p style="text-align: justify; ">Researchers have found in a new study that pretreatment with chlorhexidine and benzalkonium chloride does not improve long-term bonding in immediate dentin sealing when using a universal adhesive. However, All Bond Universal adhesive applied in the etch-and-rinse mode demonstrated better long-term bonding performance compared to its self-etch mode when antibacterial agents were used. </p><p style="text-align: justify; ">Effective and durable bonding in immediate dentin sealing is a crucial factor in the success of adhesive-bonded restorations. This study aimed to examine the effects of chlorhexidine and benzalkonium chloride pretreatments on the initial and long-term bond strength of a universal adhesive applied in two different etching modes. The research involved preparing flat dentin surfaces from extracted molars, which were divided into six groups based on pretreatment type and etching mode.</p><p style="text-align: justify; "> The adhesive was used in either etch-and-rinse or self-etch mode, followed by the application of a hydrophobic resin layer. After the provisional stage and final cementation with resin, bond strength was evaluated both immediately after application and again after one year of storage.The results indicated that pretreatment with chlorhexidine did not have a significant effect on bond strength, while pretreatment with benzalkonium chloride led to weaker immediate bonding performance when used in self-etch mode. However, in the etch-and-rinse mode, there were no substantial differences in bond strength among the pretreatment groups immediately after bonding or after one year. </p><p style="text-align: justify; ">Over time, the bond strength in the self-etch mode declined across all groups, with the chlorhexidine group showing the weakest long-term bonding. In contrast, the etch-and-rinse mode showed stable or slightly improved bond strength over time, with the benzalkonium chloride group achieving the highest values after one year. Overall, neither chlorhexidine nor benzalkonium chloride pretreatment provided additional benefits in improving long-term bonding performance in immediate dentin sealing when using the universal adhesive in this study. However, when incorporating antibacterial agents, the etch-and-rinse mode of All Bond Universal adhesive demonstrated superior long-term bonding compared to its self-etch mode. These findings suggest that the choice of etching mode plays a critical role in maintaining durable adhesive restorations.</p><div class="pasted-from-word-wrapper"><div style="text-align: justify;"></div><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Shafiei, F., Jowkar, Z., Eslamipanah, S. et al. Comparative evaluation of chlorhexidine and benzalkonium chloride pretreatments on bond strength durability of immediate dentin sealing with universal adhesive: an in vitro study. BMC Oral Health 25, 390 (2025). https://doi.org/10.1186/s12903-025-05745-5</p><div style="text-align: justify;"></div><div style="text-align: justify;"></div><div style="text-align: justify;"></div><div style="text-align: justify;"></div></div>

385. Norepinephrine as initial vasoactive agent has lower mortality rates in Pediatric Septic Shock compared to Epinephrine: JAMA

     Tue, 29 Apr 2025 14:45:23 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/13/282907-jpm-13-01548-g005.webp' /><p style="text-align: justify; ">Researchers have found in a new study that Children without known cardiac dysfunction who were treated with norepinephrine as the initial vasoactive agent for septic shock showed lower mortality rates compared to those treated with epinephrine, though both groups had similar rates of major adverse kidney events within 30 days (MAKE30). Further prospective studies are required to confirm whether norepinephrine should be the preferred first-line agent in such cases.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">There is no consensus and wide practice variation in the choice of initial vasoactive agent in children with septic shock. A study was done to determine whether receipt of epinephrine compared with norepinephrine as the first vasoactive medication administered is associated with improved outcomes among children with septic shock without known cardiac dysfunction.</p><p dir="ltr" style="text-align: justify; "> This single-center, retrospective cohort study used propensity score matching to examine encounters in which a patient was diagnosed with septic shock and required a vasoactive infusion within 24 hours of ED arrival at a freestanding quaternary care children’s hospital. Participants included patients aged 1 month to 18 years who presented to the ED and were diagnosed with septic shock without known cardiac dysfunction and began an epinephrine or norepinephrine infusion within 24 hours of ED arrival between June 1, 2017, and December 31, 2023. Data were analyzed from March 1 to December 31, 2024. </p><p dir="ltr" style="text-align: justify; "> The primary outcome was major adverse kidney events by 30 days (MAKE30). Secondary outcomes were 30-day in-hospital mortality, 3-day mortality, need for kidney replacement therapy or persistent kidney dysfunction, endotracheal intubation, mechanical ventilation days, extracorporeal membrane oxygenation, and hospital and intensive care unit length of stay. Primary and secondary outcomes were assessed with the χ2 test of proportions for binary variables and Wilcoxon rank sum test for continuous variables. </p><p dir="ltr" style="text-align: justify; ">Results Among 231 included encounters, the median (IQR) age was 11.4 (5.6-15.4) years, 126 were female (54.6%), and 142 had a medical history that predisposed them to sepsis (61.5%). Most (147 [63.6%]) initially received an epinephrine infusion and 84 (36.4%) received norepinephrine. In the epinephrine group, 9 of 147 (6.1%) met the outcome of MAKE30 and 6 of 147 (4.1%) died within 30 days. In the norepinephrine group, 3 of 84 (3.6%) met MAKE30 and there were no deaths. After inverse probability of treatment weighting, there were no significant differences in the primary outcome, MAKE30. With 2:1 propensity matching, epinephrine was associated with greater 30-day mortality compared with norepinephrine (3.7% vs 0%; risk difference: 3.7%; 95% CI, 0.2%-7.2%). In this study, those receiving epinephrine had greater 30-day mortality but no difference in MAKE30. Prospective, confirmatory studies are needed to determine if norepinephrine should be the first-line vasoactive agent in pediatric septic shock.</p><div style="text-align: justify;"></div><div style="text-align: justify;"></div><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Eisenberg MA, Georgette N, Baker AH, Priebe GP, Monuteaux MC. Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock. JAMA Netw Open. 2025;8(4):e254720. doi:10.1001/jamanetworkopen.2025.4720</p><div style="text-align: justify;"></div><div style="text-align: justify;"></div></div>

386. Self-Harm in India: Study Links Suicide Attempts and NSSI to Mental Health Disorders

     Tue, 29 Apr 2025 14:45:21 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/19/279189-self-harm.webp' /><p style="text-align: justify; ">India: A recent secondary analysis examining cases of non-suicidal self-injury (NSSI) and suicide attempts has shed light on the patterns and clinical characteristics of individuals presenting with self-harm at a tertiary care hospital. The Indian study, published in the <em>Cureus </em>Journal, identified distinct differences between suicide attempts and NSSI.&nbsp; &nbsp; &nbsp;</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The researchers reported that suicide attempts were most prevalent among individuals aged 31–40 years, with depressive disorder identified in 68.7% of cases. In contrast, non-suicidal self-injury (NSSI) was more common in the 18–30 age group and was frequently linked to substance use disorder (67.1%). They further noted that self-poisoning was the most commonly used method, possibly due to insufficient pesticide regulations.</p><p style="text-align: justify; ">The researchers note that self-harm encompasses both suicide attempts and non-suicidal self-injury (NSSI), each associated with psychiatric disorders and psychosocial stressors. While suicide attempts reflect an intent to end one’s life, NSSI often functions as a maladaptive coping strategy. In India, the stigma surrounding mental health and limited access to psychiatric care pose significant barriers to early intervention.</p><p style="text-align: justify; ">Against the above background, Kashyap Shah, Psychiatry, Mahatma Gandhi Memorial Medical College, Indore, IND, and colleagues examined the patterns of self-harm, underlying psychiatric comorbidities, and key risk factors among patients seeking care at a tertiary hospital, highlighting the need for targeted prevention strategies. </p><p style="text-align: justify; ">For this purpose, the researchers conducted a retrospective review of medical records from 165 patients who presented with suicide attempts or non-suicidal self-injury between January and June 2024. They analyzed data on demographics, psychiatric diagnoses, self-harm methods, and substance use using both descriptive and inferential statistical approaches. </p><p style="text-align: justify; ">Based on the study, the researchers reported the following findings:</p><ul><li style="text-align: justify; ">Among the 165 cases, 69 involved suicide attempts, while 96 were cases of non-suicidal self-injury (NSSI).</li><li style="text-align: justify; ">Suicide attempts were more prevalent in individuals aged 31–40 years, whereas NSSI was more common in the 18–30 age group.</li><li style="text-align: justify; ">Depressive disorder was the most frequent diagnosis among those who attempted suicide, affecting 55 individuals (68.7%).</li><li style="text-align: justify; ">Substance use disorder was more commonly associated with NSSI, reported in 51 individuals (67.1%).</li><li style="text-align: justify; ">Self-poisoning was the most frequently used method, possibly due to weak pesticide regulations in India.</li><li style="text-align: justify; ">A significant association was observed between suicide intent and a history of past suicide attempts.</li></ul><p style="text-align: justify; ">This study emphasizes the link between non-suicidal self-injury, suicide attempts, and shared risk factors. Early intervention is key to managing self-harm and preventing suicide. Immediate priorities include medical stabilization and a thorough suicide risk assessment.</p><p style="text-align: justify; ">The authors stressed that addressing psychosocial risks, administering appropriate pharmacotherapy for co-existing mental illnesses, and implementing structured post-discharge care are crucial in reducing self-harm and suicide risk.</p><p style="text-align: justify; ">They concluded that targeted interventions, including early screening and restricting access to harmful substances, could significantly improve mental health outcomes and alleviate the burden of self-harm.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Shah K, Mathur R, Mishra S, et al. (March 17, 2025) Non-suicidal Self-Injury and Suicide Attempts: A Secondary Analysis Describing the Patterns and Clinical Characteristics of Patients Presenting With Self-Harm to a Tertiary Care Hospital. Cureus 17(3): e80715. DOI 10.7759/cureus.80715</p></div><p style="text-align: justify; "><br></p>

387. Stroke Patients with Artery Dissection Face Greater Risks with IV Thrombolysis: Study Finds

     Tue, 29 Apr 2025 14:45:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/06/01/211007-ischemic-stroke.webp' /><p style="text-align: justify; "><strong>Japan</strong>: A recent study has highlighted the potential risks and outcomes associated with intravenous thrombolysis (IVT) in patients with<a href="https://medicaldialogues.in/topics/acute-ischemic-stroke-ais"> acute ischemic stroke (AIS)</a> who have underlying intracranial artery dissection (IAD). The nationwide study found that patients with AIS and IAD face a threefold higher risk of intracranial hemorrhage following<a href="https://speciality.medicaldialogues.in/topics/intravenous-thrombolysis/"> intravenous thrombolysis</a>.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">"While IAD did not increase in-hospital mortality, we observed a significant reduction in the chances of achieving functional independence at discharge. These findings highlight the importance of thorough risk assessment before administering IVT to patients with IAD, ensuring a more informed and cautious approach to treatment," the researchers wrote in the<em> International Journal of Stroke. </em></p><p style="text-align: justify; ">IVT is a widely used AIS treatment aiming to restore blood flow and minimize neurological damage. However, its safety in patients with underlying intracranial artery dissection remains uncertain due to the structural fragility of the dissected artery. This raises concerns about potential complications, including intramural hematoma exacerbation and arterial rupture, making it crucial to carefully evaluate the risks before administering IVT in such cases.</p><p style="text-align: justify; ">Given these potential risks, Yuichi Imanaka, Department of Health Security System, Center for Health Security, Graduate School of Medicine, Kyoto University, Kyoto, Japan, and colleagues aimed to determine whether IAD is associated with an increased likelihood of <a href="https://medicaldialogues.in/topics/intracerebral-hemorrhage">intracranial hemorrhage (ICH)</a> following IVT and to assess its impact on functional outcomes.</p><p style="text-align: justify; ">For this purpose, the researchers conducted a retrospective matched-pair cohort study using a nationwide inpatient database in Japan, including AIS patients treated with IVT from 2010 to 2024. They excluded cases with carotid or vertebral artery dissections, missing mRS data, or prior intra-arterial thrombolysis. Patients with IAD were matched 1:4 with non-IAD controls based on key clinical factors. Outcomes, including ICH, functional independence at discharge (mRS 0–2), and in-hospital mortality, were analyzed using multivariable logistic regression, adjusting for demographic, clinical, and hospital-related variables. </p><p style="text-align: justify; ">The key findings of the study were as follows:</p><ul><li style="text-align: justify; ">Among 83,139 AIS patients treated with IVT, 242 (0.3%) had underlying IAD (median age: 54 years; 34% women). These patients were matched with 968 non-IAD controls.</li><li style="text-align: justify; ">IAD was linked to a higher risk of ICH (OR = 3.18).</li><li style="text-align: justify; ">Patients with IAD had a lower likelihood of functional independence at discharge (OR = 0.51).</li><li style="text-align: justify; ">IAD was not associated with increased in-hospital mortality (OR = 1.09).</li></ul><p style="text-align: justify; ">"The findings suggest that patients with underlying intracranial artery dissection have a higher risk of intracranial hemorrhage and a lower likelihood of functional recovery after intravenous thrombolysis compared to those without IAD," the researchers concluded. </p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Egashira, S., Kunisawa, S., Koga, M., Ihara, M., Tsuruta, W., Uesaka, Y., Fushimi, K., Toda, T., &amp; Imanaka, Y. (2025). Safety and outcomes of intravenous thrombolysis in acute ischemic stroke with intracranial artery dissection. International Journal of Stroke. https://doi.org/10.1177/17474930251317326</p></div><p style="text-align: justify; "><br></p>

388. Dupilumab Reduces COPD Exacerbations, Shows Promise for Personalized Treatment: Study Finds

     Tue, 29 Apr 2025 14:30:40 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/01/10/229638-copd-exacerbations.webp' /><p style="text-align: justify; ">USA: A pooled analysis of two phase 3, randomized, double-blind, placebo-controlled trials has demonstrated the effectiveness of <a href="https://medicaldialogues.in/topics/dupilumab">dupilumab </a>as an add-on therapy for patients with <a href="https://medicaldialogues.in/topics/chronic-obstructive-pulmonary-disease-copd">chronic obstructive pulmonary disease (COPD) </a>with<a href="https://medicaldialogues.in/topics/type-2-inflammation"> type 2 inflammation</a>.&nbsp;&nbsp;</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The findings, published in<em> The Lancet Respiratory Medicine, </em>suggest that dupilumab, when used alongside standard triple therapy, significantly reduces the rate of moderate or severe exacerbations, offering a targeted approach for managing COPD in patients with specific clinical profiles.</p><p style="text-align: justify; ">COPD is a progressive lung disease often characterized by recurrent exacerbations that lead to worsening lung function and reduced quality of life. While standard treatments help manage symptoms, there remains a need for therapies tailored to specific disease subtypes, such as those with underlying type 2 inflammation. Dupilumab is a fully human monoclonal antibody that targets the shared receptor for IL-4 and IL-13, two key drivers of type 2 inflammation. Given their role in COPD with type 2 inflammation, Prof Surya P Bhatt, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama, Birmingham, AL, USA, and colleagues aimed to evaluate the effectiveness and safety of dupilumab in treating these patients. </p><p style="text-align: justify; ">For this purpose, the researchers conducted a pooled analysis of data from the phase 3 BOREAS and NOTUS trials, which included patients from 38 countries. Participants were 40–85 years old, had COPD diagnosed for at least a year, a smoking history of at least 10 pack-years, and experienced frequent exacerbations despite triple therapy. Patients were randomly assigned to receive either subcutaneous dupilumab 300 mg or a placebo every two weeks for 52 weeks. The study aimed to assess the effectiveness of dupilumab in reducing moderate or severe exacerbations while maintaining standard inhaled therapy. </p><p style="text-align: justify; ">Key Findings:</p><ul><li style="text-align: justify; ">One-thousand-eight hundred and seventy-four patients were enrolled in the BOREAS and NOTUS trials between May 9, 2019, and May 23, 2023. Of these, 938 (50.1%) received dupilumab, while 936 (49.9%) were given a placebo.</li><li style="text-align: justify; ">The average age was 65.1 years, with 33.2% female and 66.8% male participants. Most patients (86.9%) were White, 38.4% were from Eastern Europe, and 70.2% were former smokers.</li><li style="text-align: justify; ">Over 52 weeks, 559 moderate or severe exacerbations occurred in 36.0% of the dupilumab group, compared to 774 exacerbations in 42.1% of the placebo group.</li><li style="text-align: justify; ">Dupilumab reduced the annualized rate of moderate or severe exacerbations (0.794 vs. 1.156 in the placebo group, incidence rate ratio: 0.687).</li><li style="text-align: justify; ">The time to the first severe exacerbation was longer with dupilumab compared to placebo (0.611).</li><li style="text-align: justify; ">However, there was no significant reduction in the annualized rate of severe exacerbations (0.084 vs. 0.124).</li><li style="text-align: justify; ">The rates of treatment-related adverse events, serious adverse events, discontinuations, and deaths were similar in both groups.</li></ul><p style="text-align: justify; ">The study showed that dupilumab, when added to standard triple therapy, significantly lowered the annualized rate of moderate or severe exacerbations compared to placebo.</p><p style="text-align: justify; ">"These findings highlight its potential as a targeted treatment option for COPD patients with specific clinical profiles," the authors concluded.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Bhatt SP, Rabe KF, Hanania NA, Vogelmeier CF, Bafadhel M, Christenson SA, Papi A, Singh D, Laws E, Dakin P, Maloney J, Lu X, Bauer D, Bansal A, Abdulai RM, Robinson LB. Dupilumab for chronic obstructive pulmonary disease with type 2 inflammation: a pooled analysis of two phase 3, randomised, double-blind, placebo-controlled trials. Lancet Respir Med. 2025 Mar;13(3):234-243. doi: 10.1016/S2213-2600(24)00409-0. Epub 2025 Jan 31. PMID: 39900091.</p></div><p style="text-align: justify; "><br></p>

389. Fatty liver linked to increased risk of death from several diseases: Study

     Tue, 29 Apr 2025 14:30:36 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/02/27/203260-fatty-liver.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">A comprehensive study from Karolinska Institutet shows that people with <a href="https://medicaldialogues.in/topics/fatty-liver-disease">fatty liver disease</a> have almost twice the mortality rate of the general population. They have an increased risk of dying from both liver diseases and common diseases such as<a href="https://medicaldialogues.in/topics/cancer"> cancer</a> and <a href="https://medicaldialogues.in/topics/cardiovascular-disease">cardiovascular disease</a>, according to the study published in <em>The Journal of Hepatology</em>.</p><p style="text-align: justify;">It is estimated that one in five people in Sweden has fatty <a href="https://medicaldialogues.in/topics/liver-disease">liver disease</a> known as MASLD (metabolic dysfunction-associated steatotic liver disease), and globally it may be as many as one in four. The disease is caused by overweight or <a href="https://medicaldialogues.in/topics/obesity">obesity</a> and is characterised by an excessive accumulation of fat in the liver, which can lead to severe liver damage and <a href="https://medicaldialogues.in/topics/liver-cancer">liver cance</a>r.</p><h3 style="text-align: justify; ">Hidden health condition</h3><p style="text-align: justify;">“Many people are not aware that they have fatty liver disease because it rarely causes any symptoms in the earlier stages,” says Axel Wester, assistant professor at the Department of Medicine, Huddinge, Karolinska Institutet and physician at Karolinska University Hospital. “Our study shows that people diagnosed with MASLD have an increased risk of dying from many different diseases, not just liver disease.”</p><p style="text-align: justify;">The researchers identified all patients diagnosed with MASLD in Sweden between 2002 and 2020, more than 13,000 patients in total, and analysed their risk of death from different causes compared to the general population.</p><p style="text-align: justify;">The overall mortality rate for people with MASLD was almost twice as high. The risk was elevated for nearly all causes of death studied, but especially for death from liver disease (27 times higher mortality) and liver cancer (35 times higher mortality). However, the most common causes of death were cardiovascular disease and non-liver cancer, with mortality rates 54 and 47 per cent higher, respectively.</p><h3 style="text-align: justify; ">A holistic approach</h3><p style="text-align: justify; ">People with MASLD also had an increased risk of dying from infections, gastrointestinal diseases, respiratory diseases, endocrine diseases or external causes, but not from mental illness.</p><p style="text-align: justify;">“It is important that we do not only focus on the liver when treating patients with fatty liver disease,” says Hannes Hagström, adjunct professor at the Department of Medicine, Huddinge, Karolinska Institutet and senior physician at Karolinska University Hospital. “A holistic approach and early intervention involving different medical specialities can be crucial to improve the prognosis for these patients.”</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Issa, Gabriel et al., Cause-specific mortality in 13,099 patients with metabolic dysfunction-associated steatotic liver disease in Sweden, Journal of Hepatology, DOI:10.1016/j.jhep.2025.03.001.</p></div>

390. Adding some spice- Curcumin helps treat mycobacterium abscessus, reports research

     Tue, 29 Apr 2025 14:30:32 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/19/279173-curcumin.webp' /><p style="text-align: justify; "><a href="https://medicaldialogues.in/topics/mycobacterium-abscessus">Mycobacterium abscessus</a> is a fast-growing, pathogenic mycobacteria that can cause <a href="https://medicaldialogues.in/topics/lung-infections">lung infections</a>, and people who have respiratory conditions or are immunocompromised face a higher risk. It can also cause skin infections. The microbe is closely related to the one that causes tuberculosis and is naturally resistant to many antibiotics. Infections often require a year or more of a combination of drugs.</p><p style="text-align: justify; ">A study published this week in<i> Microbiology Spectrum</i> reports a potential way to improve treatment: Add a little spice. Researchers at Shanghai Jiao Tong University, in China, found that adding curcumin boosts the efficacy of<a href="https://medicaldialogues.in/topics/bedaquiline"> bedaquiline</a>, an antimycobacterial used to treat tuberculosis, in combating M. abscessus infections. Curcumin is the compound that gives turmeric its characteristic bright orange color. </p><p style="text-align: justify; ">“This low-toxicity natural product combined with existing drugs could pioneer new treatment pathways for resistant infections,” said microbiologist Zhe Wang, Ph.D, senior author on the study. “It’s particularly relevant in immunocompromised populations,” Wang added, who are more vulnerable to these infections. </p><p style="text-align: justify;">Wang’s lab focuses on innovative approaches to treating infectious disease; those approaches include repurposing known drugs and finding ways to combine natural products with known treatments. They knew that treatment for M. abscessus often leads to poor outcomes—only about half of people who undergo treatment become non-infectious, according to previous studies. Bedaquiline is an antibiotic used to treat multidrug-resistant tuberculosis and has shown some promise in relieving symptoms of non-tuberculosis mycobacterial infections, including M. abscessus. However, the drug does not eliminate all the infectious microbes from a sample. </p><p style="text-align: justify;">The researchers, searching for ways to boost the efficacy of bedaquiline, investigated curcumin, which has long been used in traditional Asian medicine to treat a wide variety of conditions. Previous pharmacological studies suggest that curcumin has protective effects against tuberculosis. </p><p style="text-align: justify;">In lab studies, the researchers found that bedaquiline alone first inhibited the growth of M. abscessus, but the bacteria began to grow again after 2 weeks. The combination of the drug and curcumin, however, suppressed the growth and reproduction of the bacteria, suggesting that curcumin may act as an antibiotic resistance breaker. In mice, the researchers found that the drug combination slowed or stopped infection better than either compound alone, both in immunocompromised mice and those with a healthy immune system. “The combination demonstrates synergistic enhancement of antibacterial activity and improved infection clearance,” Wang said. </p><p style="text-align: justify; ">The researchers are now investigating the specific molecular targets that play a role in the mechanisms behind the effects of the combination therapy. They’re also evaluating the combination against other resistant mycobacterial strains and conducting safety assessment to prepare for clinical trials and, down the road, the development of new therapeutics. “This study highlights the innovative value of combining drug repurposing with natural products,” Wang said.&nbsp;</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Luo, D., et al. (2025) Curcumin enhances bedaquiline’s efficacy against Mycobacterium abscessus: in vitro and in vivo evidence. Microbiology Spectrum. doi.org/10.1128/spectrum.02295-24.</p>

391. 61 Formulations declared Not of standard quality as per data provided by states: CDSCO Drug Alert

     Tue, 29 Apr 2025 12:30:35 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/01/23/230825-cdsco-drug-alert.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; "><b>New Delhi:</b> In line with the 'Not of Standard Quality' data provided by states, the apex drug regulatory body, the Central Drug Standard Control Organization (CDSCO), in its latest drug alert, has flagged 61 medicine batches for failing to qualify for a random sample test for March 2025.</p><div class="pasted-from-word-wrapper" style="text-align: justify; ">The list of drugs declared not of standard quality includes Norfloxacin Tablets manufactured by Revat Laboratories, Parenteral preparations, Oxytetracycline Hydrochloride Injection I.P. (Steclin Injection), Veterinary manufactured by Zenex Animal Health, Telmivaz Tablets, Telmisartan Tablets IP 40mg manufactured by Mascot Healthseries, Norfloxacin Tablets manufactured by Revat Laboratories, Folic Acid Tablets IP 5mg manufactured by Adroit Pharmaceuticals, Albendazole Tablets IP 400mg manufactured by Samkem, Albendazole Tablets IP 400mg manufactured by Samkem other.</div><p style="text-align: justify; ">This came as part of the continuous regulatory surveillance, where drug samples are picked from sales/distribution points, analyzed, and lists of Not of Standard Quality (NSQ) drugs are displayed on the CDSCO portal on a monthly basis.</p><p style="text-align: justify; ">"The purpose of displaying the NSQ list is to make stakeholders aware about the NSQ batches identified in the market." the alert added.</p><div class="pasted-from-word-wrapper" style="text-align: justify; ">The drugs that fail to meet the quality standards or specifications are known as Non-Standard Quality (NSQ) drugs. Further, the term ‘standards of quality’ is defined under Section 16 (1) (a) of the Drugs and Cosmetics Act, 1940, which states that the ‘standards of quality’ mean that the drug complies with the standards set out in the Second Schedule of the said Act.</div><p style="text-align: justify; ">Furthermore, the alert mentioned that NSQ data received in EXCEL SHEET from State Drugs Licensing Authorities of Kerala, West Bengal, Telangana Jammu and Kashmir, Himachal Pradesh and Puducherry, (PDF Format), Assam (PDF Format), Tripura (PDF Format), for the month of March, 2025 as per DCG (I) Circular dated 09.02.2024.</p><p style="text-align: justify; ">Further, it added that State Drugs Licensing Authorities of Andhra Pradesh, Goa, Arunachal Pradesh, Bihar, Chhattisgarh, Chandigarh, Gujarat, Haryana, Jharkhand, Karnataka, Manipur, Madhya Pradesh, Maharashtra, Meghalaya, Mizoram, Nagaland, Odisha, Punjab, Rajasthan, Sikkim, Tamil Nadu, Delhi, Uttarakhand, Uttar Pradesh, Andaman and Nicobar Islands, Dadar and Nagar Haveli, Daman and Diu, Ladakh, Lakshadweep have not submitted any data in respect of the Not of Standard Quality (NSQ) Alert for the Month of March, 2025 as per DCG(I) Circular dated 09.02.2024.</p><div class="pasted-from-word-wrapper"><div class="WordSection1"><p style="text-align: justify; ">B. <u>NOT OF STANDARD QUALITY ALERT FOR THE MONTH OF MARCH– 2025</u> (State Laboratories)</p><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"><p class="TableParagraph">S.No</p></td><td width="132" valign="top"><p class="TableParagraph">Product/Drug Name</p></td><td width="66" valign="top"><p class="TableParagraph">Batch No.</p></td><td width="95" valign="top"><p class="TableParagraph">Manufactu ring Date</p></td><td width="76" valign="top"><p class="TableParagraph">Expiry Date</p></td><td width="238" valign="top"><p class="TableParagraph">Manufactured By</p></td><td width="178" valign="top"><p class="TableParagraph">NSQ Result</p></td><td width="189" valign="top"><p class="TableParagraph">Reported by State Laboratory</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">1.</p></td><td width="132" valign="top"><p class="TableParagraph">Norfloxacin Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">RNFT- 016</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">Sep-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Revat Laboratories Pvt.Ltd, 12-321, Opp IDA Kurnool road, Pernamitta, Ongole - 523002 Andhra Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Dissolution does not comply as per IP 2022.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">2.</p></td><td width="132" valign="top"><p class="TableParagraph">Parenteral preprations, Oxytetracycline Hydrochloride Injection I.P. (Steclin Injection),</p><p class="TableParagraph">Veterinary</p></td><td width="66" valign="top"><p class="TableParagraph">STIA23 93</p></td><td width="95" valign="top"><p class="TableParagraph">Nov-23</p></td><td width="76" valign="top"><p class="TableParagraph">Oct-25</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Zenex Animal Health India Pvt.Ltd, Plot No. 1&amp;2, Near Erthardt Leimer, Sarkhej Bawla Highway, Sari Patiya, Dist: Ahmedabad - 382220. Gujarat.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not comply description as per IP 2022 Oxytetracycline Hydrochloride Injection I.P (Veterinary Monograph)</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">3.</p></td><td width="132" valign="top"><p class="TableParagraph">Telmivaz Tablets, Telmisartan Tablets IP 40mg,</p></td><td width="66" valign="top"><p class="TableParagraph">CMT242 202B</p></td><td width="95" valign="top"><p class="TableParagraph">Nov-24</p></td><td width="76" valign="top"><p class="TableParagraph">Oct-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Mascot Healthseries Pvt.Ltd, At - Plot No. 52, Sec-6A, IIE, Sidcul, Haridwar - 249 403, Uttarakhand.</p><p class="TableParagraph">Mrkt: Saanso Life Sciences Pvt.Ltd, 1 st Floor, Quadrant 2, A1, Cyber Towers, Hitech city, Madhapur, Hyderabad, Telangana - 500081.</p></td><td width="178" valign="top"><p class="TableParagraph">The tablet coating was found to adhere to the foil, and it was observed that the coating peeled off during the removal of the tablets from the strip.</p><p class="TableParagraph">Hence, the sample does not comply with the test for</p><p class="TableParagraph">Description of Tablets.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">4.</p></td><td width="132" valign="top"><p class="TableParagraph">Norfloxacin Tablets IP 400mg</p></td><td width="66" valign="top"><p class="TableParagraph">RNFT- 017</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">Sep-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Revat Laboratories Pvt.Ltd, 12-321, Opp IDA Kurnool road, Pernamitta, Ongole - 523002 Andhra Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample Does not complies in respect of Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">5.</p></td><td width="132" valign="top"><p class="TableParagraph">Folic Acid Tablets IP 5mg</p></td><td width="66" valign="top"><p class="TableParagraph">TS7552</p></td><td width="95" valign="top"><p class="TableParagraph">Jan-24</p></td><td width="76" valign="top"><p class="TableParagraph">Dec-25</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Adroit Pharmaceuticals Pvt.Ltd, 46, Garoba Maidan, Nagpur -</p><p class="TableParagraph">8, Maharashtra.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample Does not complies in respect of Dissolution</p><p class="TableParagraph">Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">6.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/009 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Samkem 15-B &amp; 10-B, Akvn Industrialarea, Rangwasa, Rao,</p><p class="TableParagraph">Indore - 453331, (MP), Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample Does not complies in respect of Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">7.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/017 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Samkem 15-B &amp; 10-B, Akvn Industrialarea, Rangwasa, Rao,</p><p class="TableParagraph">Indore - 453331, (MP), Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample Does not complies in respect of Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection2"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"><p class="TableParagraph">8.</p></td><td width="132" valign="top"><p class="TableParagraph">Panaval-40 tablets, Pantoprazole Gastro-resistant tablets IP 40 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">BLT- 231650</p></td><td width="95" valign="top"><p class="TableParagraph">Feb-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jan-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Brit Life science Sainwala, Kaula Wala Bhoodroad, Kala Amb, Distt. Sirmour, HP-173 030. Himachal Pradesh. Mrkt:</p><p class="TableParagraph">M/s. Avel Life Sciences.</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not complies for Dissolution test a per IP Secifications, hence the sample is of Not</p><p class="TableParagraph">of Standard Quality.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">9.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets I.P. 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">C25F94 4017</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-24</p></td><td width="76" valign="top"><p class="TableParagraph">May-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Concept Pharmaceuticals Ltd, Khasra No. 104, Asaf Nagar, Roorkee - 247 667. Uttarakhand.</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not meet the Dissolution test parameter as per IP specifications, hence it is of</p><p class="TableParagraph">Not of Standard Quality.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">10.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/024 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa,</p><p class="TableParagraph">Rao, Indore - 453331. (M.P). Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">11.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/010 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa, Rao, Indore - 453331. (M.P). Madhya Pradesh. (WHO-GMP &amp; GLP Certified Company)(An ISO 9001:</p><p class="TableParagraph">2015 Certified Company) Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">12.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/012 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa, Rao, Indore - 453331. (M.P). Madhya Pradesh. (WHO-GMP &amp; GLP Certified Company)(An ISO 9001: 2015 Certified Company) Madhya</p><p class="TableParagraph">Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">13.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/013 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa, Rao, Indore - 453331. (M.P). Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">14.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/025 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa, Rao, Indore - 453331. (M.P). Madhya</p><p class="TableParagraph">Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">15.</p></td><td width="132" valign="top"><p class="TableParagraph">Albendazole Tablets IP 400 mg,</p></td><td width="66" valign="top"><p class="TableParagraph">T24/012 A</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Samkem 15-B &amp; 10-B,</p><p class="TableParagraph">A.K.V.N. Industrial Area, Rangwasa, Rao, Indore - 453331. (M.P). Madhya Pradesh.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not meets the Specifications wrt.</p><p class="TableParagraph">Dissolution Test as per IP.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">16.</p></td><td width="132" valign="top"><p class="TableParagraph">Moxirid-LB 625 Tablets, Axoxycillin, Potassium Clavulanate &amp; Lactic Acid Bacillus</p><p class="TableParagraph">Tablets</p></td><td width="66" valign="top"><p class="TableParagraph">BT0324 089A</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">Mar-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Alencure Bitech Pvt.Ltd, village: Nagal, Suketi road, Pharmaceuticals O Moginanand Kala Amb, Distt: Sirmouour - 173 030 (HP). Himachal Pradesh.</p><p class="TableParagraph">Mrkt: Trullp Pharma, H-34B, Village</p></td><td width="178" valign="top"><p class="TableParagraph">MISBRANDED</p><p class="TableParagraph">The sample is deemed to be misbranded as it is only indicated as approved colur used on the label of the product but failed to</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr></tbody></table></div><div class="WordSection3"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"></td><td width="132" valign="top"></td><td width="66" valign="top"></td><td width="95" valign="top"></td><td width="76" valign="top"></td><td width="238" valign="top"><p class="TableParagraph">Saketri, Panchkula Haryana - 134 109.</p></td><td width="178" valign="top"><p class="TableParagraph">indicate the common name of the colur on the label as required as per Rule 127(2) of Drugs Rules, 1945.</p><p class="TableParagraph">Hence the drug is a Misbranded drug as per Section 17 of Drugs and</p><p class="TableParagraph">Cosmetics Act 1940.</p></td><td width="189" valign="top"></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">17.</p></td><td width="132" valign="top"><p class="TableParagraph">Paracetamol IP Paediatric syrup 125mg/5ml</p></td><td width="66" valign="top"><p class="TableParagraph">KGP. 240227.</p></td><td width="95" valign="top"><p class="TableParagraph">Feb-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jan-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Karuppharma Pvt.Ltd., D. NO. 2-67, Sy.No.68, Kachivani Singaram, Ghatkesar mandal, Medchal - Malkajgiri Dist. Telangana.</p></td><td width="178" valign="top"><p class="TableParagraph">MISBRANDED</p><p class="TableParagraph">The label of the sample indicates only Approved Coloures Used but failed to indicate the common name of the color, as required as per Rule 127(2) of the Drugs Rules, 1945. Hence the drug is deemed to be Misbranded as per Section 17 of the Drugs and Cosmetics Act, 1940,</p><p class="TableParagraph">as the drug is not labeled in the prescribed manner.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">18.</p></td><td width="132" valign="top"><p class="TableParagraph">Mefifresh Tablets, Mefenamic Acid &amp; Dicyclomine Hydrochloride Tablets,</p></td><td width="66" valign="top"><p class="TableParagraph">T09243 9</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Aug-27</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: M/s. Swefn Pharmaceuticals Pvt.Ltd, 7, Sopan kesar Industrial Hub, Vil. Moraiya, Tal. Sanand, Dist. Ahmedabad - 382213 Gujarat.</p><p class="TableParagraph">Mrkt: M/s. Smart Laboratories Pvt.Ltd, 1004, Brooklyn Tower, Nr. YMCA club, S.G. Highway, Ahmedabad 380051 (Guj).</p></td><td width="178" valign="top"><p class="TableParagraph">MISBRANDED</p><p class="TableParagraph">The drug product Mefenamic Acid and Dicyclomine HCL tablets is official in Indian Pharmacopoeia. But the letters IP is not mentioned on the strip after the product name Mefenamic Acid and Dicyclomine HCL tablets. Hence it is Misbranded drug under section 17 of Drugs and</p><p class="TableParagraph">Cosmetics Act, 1940.</p></td><td width="189" valign="top"><p class="TableParagraph">State Lab,</p><p class="TableParagraph">Drugs Control Laboratory, Telangana.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">19.</p></td><td width="132" valign="top"><p class="TableParagraph">Glimepiride Tab IP</p></td><td width="66" valign="top"><p class="TableParagraph">GP4039</p></td><td width="95" valign="top"><p class="TableParagraph">Mar-24</p></td><td width="76" valign="top"><p class="TableParagraph">Aug-26</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala State Drugs and Pharmaceuticals Limited, Kalavoor</p><p class="TableParagraph">.P.O, Alappuzha -688 522</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘Dissolution’ Specified in the laboratory</p><p class="TableParagraph">protocol as per IP</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">20.</p></td><td width="132" valign="top"><p class="TableParagraph">Beauty care EGG Protein Shampoo</p></td><td width="66" valign="top"><p class="TableParagraph">3</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-24</p></td><td width="76" valign="top"><p class="TableParagraph">May-26</p></td><td width="238" valign="top"><p class="TableParagraph">Universal Cosmetics Industries, B- 29, Balaji Ind.Est, Akruli Road, Kandivali(E), Mumbai 101, Maharashtra</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for microbial limit as specified in the Laboratory Protocol as per IS 14648 : 2011 for</p><p class="TableParagraph">microbiological examination of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection4"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"><p class="TableParagraph">21.</p></td><td width="132" valign="top"><p class="TableParagraph">Lilium Fruit Massage Cream</p></td><td width="66" valign="top"><p class="TableParagraph">MCF240 8118</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before 36 Months from the</p><p class="TableParagraph">date of Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Lilium Cosmetics Pvt Ltd,A-97, sector-80, Gautham Budh Nagar,Noida, Uttarpradesh-201306</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for Heavy metals (as pb) parts per million, as specifed in the Laboratory protocol as per IS 6608:2004 for</p><p class="TableParagraph">specification of skin cream</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">22.</p></td><td width="132" valign="top"><p class="TableParagraph">Silk &amp; Sheen sandal face pack</p></td><td width="66" valign="top"><p class="TableParagraph">01</p></td><td width="95" valign="top"><p class="TableParagraph">Nov-24</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before 30 Months from the date of Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Kamal Home products, Gala No. 104, Nirav-7, S No.44,45,93,94, Village Sativali, Vasai(E), Distt.Thane-401 208</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests for total viable count and Gram negative pathogens, psuedomonas aeruginosa as specified in the Laboratory Protocol as per IS 14648 : 2011 for</p><p class="TableParagraph">microbiological examination of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">23.</p></td><td width="132" valign="top"><p class="TableParagraph">Glimepiride Tab IP 1 mg</p></td><td width="66" valign="top"><p class="TableParagraph">GP4053</p></td><td width="95" valign="top"><p class="TableParagraph">Mar-24</p></td><td width="76" valign="top"><p class="TableParagraph">Feb-26</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala State Drugs and Pharmaceuticals Limited, Kalavoor</p><p class="TableParagraph">.P.O, Alappuzha -688 522</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the Descriptive part for tablets as specified in the Laboratory Protocol as per IP</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">24.</p></td><td width="132" valign="top"><p class="TableParagraph">Karas 2 H Hygiene Hand Sanitizer 500 ml</p></td><td width="66" valign="top"><p class="TableParagraph">IIACCJ2 4</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">2 Yrs. From the date of Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Karas Healthcare Private Ltd, 16/164B, Paravoor Road, Mannam, Vaniyakkad, North Paravur, Ernakulam, 683 520</p></td><td width="178" valign="top"><p class="TableParagraph">The sample gives negative results for the presence of Ethyl , Alcohol and positive results for the presence of Methanol as per IP. The sample contains 78.39% v/v of Methanol as specified in the Laboratory Protocol.</p><p class="TableParagraph">Hence the sample is spurious and declared as NSQ</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">25.</p></td><td width="132" valign="top"><p class="TableParagraph">Vitamin B 12 Injection IP</p></td><td width="66" valign="top"><p class="TableParagraph">CHI – 40139</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-24</p></td><td width="76" valign="top"><p class="TableParagraph">May-26</p></td><td width="238" valign="top"><p class="TableParagraph">Cotec Healthcare Pvt.Ltd, K.H.No. 593/1 Roorkee , Dehradun , High way, Kishanpur, Roorkee- 247667</p><p class="TableParagraph">Uttarakhand</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘Sterility’ and ‘Assay’ as per IP</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">26.</p></td><td width="132" valign="top"><p class="TableParagraph">Blue Heaven Get matte Lipstick (4g)</p></td><td width="66" valign="top"><p class="TableParagraph">KA4A1</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before 36 Months from Mfd.</p></td><td width="238" valign="top"><p class="TableParagraph">Blue Heaven Cosmetics (P) Ltd,Plot No. 15, Sector -4, IMT, Manesar,</p><p class="TableParagraph">Gurugram, Haryana- 122052</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol as</p><p class="TableParagraph">per Cosmetic Rules, 2020 for Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">27.</p></td><td width="132" valign="top"><p class="TableParagraph">Faiza Beauty Cream 45 gm</p></td><td width="66" valign="top"><p class="TableParagraph">24FX23</p></td><td width="95" valign="top"><p class="TableParagraph">Apr-24</p></td><td width="76" valign="top"><p class="TableParagraph">Apr-27</p></td><td width="238" valign="top"><p class="TableParagraph">Poonia Brothers Pvt Ltd</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in</p><p class="TableParagraph">finished cosmetics products as specified in</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection5"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"></td><td width="132" valign="top"></td><td width="66" valign="top"></td><td width="95" valign="top"></td><td width="76" valign="top"></td><td width="238" valign="top"></td><td width="178" valign="top"><p class="TableParagraph">the Laboratory protocol as per Cosmetic Rules, 2020 for Standards of Cosmetics</p></td><td width="189" valign="top"></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">28.</p></td><td width="132" valign="top"><p class="TableParagraph">Goree Day &amp; Night Beauty Cream</p></td><td width="66" valign="top"><p class="TableParagraph">GDN17 5</p></td><td width="95" valign="top"><p class="TableParagraph">Apr-24</p></td><td width="76" valign="top"><p class="TableParagraph">Mar-27</p></td><td width="238" valign="top"><p class="TableParagraph">Goree Cosmetics (pvt)Ltd, Made in Pakisthan</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol as per Cosmetic Rules,</p><p class="TableParagraph">2020 for Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">29.</p></td><td width="132" valign="top"><p class="TableParagraph">Sandal Beauty Cream</p></td><td width="66" valign="top"><p class="TableParagraph">133E</p></td><td width="95" valign="top"><p class="TableParagraph">NIL</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before July 27</p></td><td width="238" valign="top"><p class="TableParagraph">MMC Cosmetics Pvt Ltd, Made in Pakisthan</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol as per Cosmetic Rules, 2020 for Standards of</p><p class="TableParagraph">Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">30.</p></td><td width="132" valign="top"><p class="TableParagraph">Fem creme Bleach</p></td><td width="66" valign="top"><p class="TableParagraph">BM1516</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jun-26</p></td><td width="238" valign="top"><p class="TableParagraph">Dabur India Ltd, Village Manakpur, Tehsil, Baddi, Distt, Soaln (HP)- 174 101</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol . Does not conform to Cosmetic Rules, 2020 for</p><p class="TableParagraph">Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">31.</p></td><td width="132" valign="top"><p class="TableParagraph">Faiza Moisture Blancing Whitening Face Wash</p></td><td width="66" valign="top"><p class="TableParagraph">NIL</p></td><td width="95" valign="top"><p class="TableParagraph">Jan-23</p></td><td width="76" valign="top"><p class="TableParagraph">Jun-26</p></td><td width="238" valign="top"><p class="TableParagraph">Poonia Brothers Pvt Ltd</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol . Does not conform to Cosmetic Rules, 2020 for</p><p class="TableParagraph">Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">32.</p></td><td width="132" valign="top"><p class="TableParagraph">Top UP Matte Super Light Liquid Lipstick</p></td><td width="66" valign="top"><p class="TableParagraph">202742</p><p class="TableParagraph">6</p></td><td width="95" valign="top"><p class="TableParagraph">Apr-23</p></td><td width="76" valign="top"><p class="TableParagraph">Apr-27</p></td><td width="238" valign="top"><p class="TableParagraph">Yiwn Baolina Cosmetics Co Ltd, Yiwn Ltd, Yiting Town, Yiwn city, Jinhua city, Zhejiang Province, China</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetics products as specified in the Laboratory protocol . Does not conform to</p><p class="TableParagraph">Cosmetic Rules, 2020 for Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">33.</p></td><td width="132" valign="top"><p class="TableParagraph">Quench Ultra</p><p class="TableParagraph">Light Nourishing Face and Body</p></td><td width="66" valign="top"><p class="TableParagraph">BB54</p></td><td width="95" valign="top"><p class="TableParagraph">May-23</p></td><td width="76" valign="top"><p class="TableParagraph">Apr-27</p></td><td width="238" valign="top"><p class="TableParagraph">Velvette life style Pvt Ltd, B-1004, Palatial Heights, Andheri (E),</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests for Total</p><p class="TableParagraph">fatty substance content percent by mass, Total</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection6"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"></td><td width="132" valign="top"><p class="TableParagraph">Cream (with Avocado Vitamin C&amp;E )</p></td><td width="66" valign="top"></td><td width="95" valign="top"></td><td width="76" valign="top"></td><td width="238" valign="top"><p class="TableParagraph">Mumbai- 400072, Maharashtra (Marketed By)</p></td><td width="178" valign="top"><p class="TableParagraph">residue percent by mass and Heavy metals as Lead (pb) parts per million as per IS 6608: 2004 for</p><p class="TableParagraph">specification of skin cream</p></td><td width="189" valign="top"></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">34.</p></td><td width="132" valign="top"><p class="TableParagraph">Silk &amp; Sheen Apricot Facial Scrub</p></td><td width="66" valign="top"><p class="TableParagraph">01</p></td><td width="95" valign="top"><p class="TableParagraph">Jul-24</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before 30 Months from the date of Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Kamal Home products, Gala No. 104, Nirav-7, S No.44,45,93,94, Village Sativali, Vasai (E),Taluka Vasai, Distt.Thane-401 208</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetic products as specified in the Laboratory protocol as per Cosmetic Rules, 2020 for</p><p class="TableParagraph">Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">35.</p></td><td width="132" valign="top"><p class="TableParagraph">Red four seven seas twist matte lipstick</p></td><td width="66" valign="top"><p class="TableParagraph">NG229</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jun-29</p></td><td width="238" valign="top"><p class="TableParagraph">Seven seas Beauty products, Add. Ground floor, B-68, Gt karnal Road, Industrial area, Delhi-110033 (Marketed by)</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetic products as specified in the Laboratory protocol as per Cosmetic Rules, 2020 for</p><p class="TableParagraph">Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">36.</p></td><td width="132" valign="top"><p class="TableParagraph">Nature’s Essence Moisturing aloe beauty gel</p></td><td width="66" valign="top"><p class="TableParagraph">BCC4A 3</p></td><td width="95" valign="top"><p class="TableParagraph">Mar-24</p></td><td width="76" valign="top"><p class="TableParagraph">Best Before 36 Months from the date Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Esme Consumer Pvt Ltd,8, IP-II Salempur, Mehdood Haridwar- 249402</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of ‘mercury, parts per million’ as specified in the Laboratory protocol as per IS 18429 : 2023 for</p><p class="TableParagraph">specification of skin gel</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">37.</p></td><td width="132" valign="top"><p class="TableParagraph">Lipgloss ES-181</p></td><td width="66" valign="top"><p class="TableParagraph">GL8024</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-23</p></td><td width="76" valign="top"><p class="TableParagraph">Oct-28</p></td><td width="238" valign="top"><p class="TableParagraph">Shubh Laxmi Traders (imported by)</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test for the content of mercury in finished cosmetic products as specified in the Laboratory protocol as per Cosmetic Rules, 2020 for</p><p class="TableParagraph">Standards of Cosmetics</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">38.</p></td><td width="132" valign="top"><p class="TableParagraph">Niyo Plus Baby Shampoo</p></td><td width="66" valign="top"><p class="TableParagraph">BBS121</p></td><td width="95" valign="top"><p class="TableParagraph">Nov-24</p></td><td width="76" valign="top"><p class="TableParagraph">Oct-26</p></td><td width="238" valign="top"><p class="TableParagraph">Jeevanam Healthcare, Punalur, Kollam, Kerala(Marketed by)</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘Total microbial count , CFU/ml’ as specified in the Laboratory Protocol as per IS 17117 : 2019 for</p><p class="TableParagraph">specification of hair shampoo for babies.</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">39.</p></td><td width="132" valign="top"><p class="TableParagraph">Fexofenadine Tab IP [Fexodil-180]</p></td><td width="66" valign="top"><p class="TableParagraph">T – 3105</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">Sep-26</p></td><td width="238" valign="top"><p class="TableParagraph">Jackson Laboratories Pvt Ltd, 22-24, Majitha Road, Byepass, Amritsar -</p><p class="TableParagraph">143 001</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘Dissolution’ as per IP</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">40.</p></td><td width="132" valign="top"><p class="TableParagraph">Paracetamol Tab IP 500 mg</p></td><td width="66" valign="top"><p class="TableParagraph">D 2999/24</p><p class="TableParagraph">-25</p></td><td width="95" valign="top"><p class="TableParagraph">NIL</p></td><td width="76" valign="top"><p class="TableParagraph">NIL</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala Medical services Corporation Limited, Thycaud P.O, Thiruvananthapuram</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests dissolution specified in the Laboratory Protocol</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection7"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"><p class="TableParagraph">41.</p></td><td width="132" valign="top"><p class="TableParagraph">Paracetamol Tab IP 500 mg</p></td><td width="66" valign="top"><p class="TableParagraph">D 3212/24</p><p class="TableParagraph">-25</p></td><td width="95" valign="top"><p class="TableParagraph">NIL</p></td><td width="76" valign="top"><p class="TableParagraph">NIL</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala Medical services Corporation Limited, Thycaud P.O, Thiruvananthapuram</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests dissolution specified in the Laboratory Protocol</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">42.</p></td><td width="132" valign="top"><p class="TableParagraph">Paracetamol Tabl IP 500 mg</p></td><td width="66" valign="top"><p class="TableParagraph">D 3213/24</p><p class="TableParagraph">-25</p></td><td width="95" valign="top"><p class="TableParagraph">NIL</p></td><td width="76" valign="top"><p class="TableParagraph">NIL</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala Medical services Corporation</p><p class="TableParagraph">Limited, Thycaud P.O, Thiruvananthapuram</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests dissolution</p><p class="TableParagraph">specified in the Laboratory Protocol</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">43.</p></td><td width="132" valign="top"><p class="TableParagraph">Amrutharishtam</p></td><td width="66" valign="top"><p class="TableParagraph">1031</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">5 Yrs from the date of</p><p class="TableParagraph">Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Vaidyasala Veetil Oushadhasala, Kulanjiyil, Elamadu.P.O, Kollam-691 539</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘Total Solids’ as specified in the Laboratory protocol as per</p><p class="TableParagraph">API</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">44.</p></td><td width="132" valign="top"><p class="TableParagraph">Dasamularishtam</p></td><td width="66" valign="top"><p class="TableParagraph">1042</p></td><td width="95" valign="top"><p class="TableParagraph">Jan-25</p></td><td width="76" valign="top"><p class="TableParagraph">5 Yrs from the date of Mfg.</p></td><td width="238" valign="top"><p class="TableParagraph">Vaidyasala Veetil Oushadhasala, Kulanjiyil, Elamadu.P.O, Kollam-691 539</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the test ‘pH’ ,‘Total Solids’ ‘Specific Gravity’, and ‘Alcohol Content’ as</p><p class="TableParagraph">specified in the Laboratory protocol as per API</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">45.</p></td><td width="132" valign="top"><p class="TableParagraph">Avipathi Choornam</p></td><td width="66" valign="top"><p class="TableParagraph">AV 461625</p></td><td width="95" valign="top"><p class="TableParagraph">Jan-25</p></td><td width="76" valign="top"><p class="TableParagraph">Dec-26</p></td><td width="238" valign="top"><p class="TableParagraph">Changethu Herbs &amp; Drugs, Thonnallur, Pandalam</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests ‘Total sugar’, ‘Alcohol soluble Extractive ’ and ‘Water soluble Extractive’, as</p><p class="TableParagraph">specified in the Laboratory Protocol as per API</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">46.</p></td><td width="132" valign="top"><p class="TableParagraph">Paracetamol Tab IP 500 mg</p></td><td width="66" valign="top"><p class="TableParagraph">D 3103/24</p><p class="TableParagraph">-25</p></td><td width="95" valign="top"><p class="TableParagraph">NIL</p></td><td width="76" valign="top"><p class="TableParagraph">NIL</p></td><td width="238" valign="top"><p class="TableParagraph">Kerala Medical services Corporation Limited, Thycaud P.O, Thiruvananthapuram</p></td><td width="178" valign="top"><p class="TableParagraph">It fails the tests for dissolution and descriptive part for tablets as specified in the Laboratory Protocol as per IP</p></td><td width="189" valign="top"><p class="TableParagraph">Drugs Testing Laboratory Thiruvananthapuram</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">47.</p></td><td width="132" valign="top"><p class="TableParagraph">Sodium Valporate Tablets I.P. 500mg.</p></td><td width="66" valign="top"><p class="TableParagraph">SGT- 24173</p></td><td width="95" valign="top"><p class="TableParagraph">Apr-24</p></td><td width="76" valign="top"><p class="TableParagraph">May-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s. Spectrum Formulation Pvt. Ltd., Khasra No. 12, Makhanpur, Bhagwanpur, Roorkee, Haridwar -</p><p class="TableParagraph">247 661, U.K.</p></td><td width="178" valign="top"><p class="TableParagraph">Does not conform to I.P.</p></td><td width="189" valign="top"><p class="TableParagraph">State Drugs Testing Laboratory, Kolkata, West Bengal.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">48.</p></td><td width="132" valign="top"><p class="TableParagraph">Telvas H 40/12.5 (Telmisartan &amp; Hydrochlorothiazide Tablets I.P.)</p></td><td width="66" valign="top"><p class="TableParagraph">SPB240 306</p></td><td width="95" valign="top"><p class="TableParagraph">Feb-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jan-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s. Aristo Pharmaceutical Pvt. Ltd., Plot No. 2040-46, N.H.-10, Baghey Khola, P.O. Majhitar, East Sikkim-737 136.</p></td><td width="178" valign="top"><p class="TableParagraph">Does not conform to I.P.</p></td><td width="189" valign="top"><p class="TableParagraph">State Drugs Testing Laboratory, Kolkata, West Bengal.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">49.</p></td><td width="132" valign="top"><p class="TableParagraph">Telso 80</p><p class="TableParagraph">(Telmisartan Tab I.P.)</p></td><td width="66" valign="top"><p class="TableParagraph">MT2321 76</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-23</p></td><td width="76" valign="top"><p class="TableParagraph">May-25</p></td><td width="238" valign="top"><p class="TableParagraph">M/s. Mascot Health Series Pvt. Ltd.,</p><p class="TableParagraph">Plot No. 79, 80, Sec-6A, IIE, Sidcul, Haridwar-249403</p></td><td width="178" valign="top"><p class="TableParagraph">Does not conform to I.P.</p></td><td width="189" valign="top"><p class="TableParagraph">State Drugs Testing</p><p class="TableParagraph">Laboratory, Kolkata, West Bengal.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">50.</p></td><td width="132" valign="top"><p class="TableParagraph">Telvas-AM (Telmisartan &amp; Amlodipine Tablets I.P.)</p></td><td width="66" valign="top"><p class="TableParagraph">BPG241 827</p></td><td width="95" valign="top"><p class="TableParagraph">Jul-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jun-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s. Aristo Pharmaceutical Pvt. Ltd., Vill. Makhnumajra, P.O. Bhud, Dist. Solan, H.P.-173 205.</p></td><td width="178" valign="top"><p class="TableParagraph">Does not conform to I.P.</p></td><td width="189" valign="top"><p class="TableParagraph">State Drugs Testing Laboratory, Kolkata, West Bengal.</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">51.</p></td><td width="132" valign="top"><p class="TableParagraph">Telvas 40 (Telmisartan Tablets I.P. 40mg.)</p></td><td width="66" valign="top"><p class="TableParagraph">SPB240 221</p></td><td width="95" valign="top"><p class="TableParagraph">Feb-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jan-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s. Aristo Pharmaceutical Pvt. Ltd., Plot No. 2040-46, N.H.-10, Baghey</p><p class="TableParagraph">Khola, P.O. Majhitar, East Sikkim-737 136.</p></td><td width="178" valign="top"><p class="TableParagraph">Does not conform to I.P.</p></td><td width="189" valign="top"><p class="TableParagraph">State Drugs Testing Laboratory, Kolkata, West Bengal.</p></td></tr></tbody></table></div><div style="text-align: justify;"></div><div class="WordSection8"><table border="1" cellspacing="0" cellpadding="0" style="text-align: justify; "><tbody><tr><td width="73" valign="top"><p class="TableParagraph">52.</p></td><td width="132" valign="top"><p class="TableParagraph">Shafcin-650</p></td><td width="66" valign="top"><p class="TableParagraph">AT-119</p></td><td width="95" valign="top"><p class="TableParagraph">Aug-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jul-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Ambrosia Pharma , 91 , Indl. Estate , Zainakot Srinagar</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not confirm to IP 2022 requirement with respect to Dissolution Test</p></td><td width="189" valign="top"><p class="TableParagraph">Drug Testing Laboratory Srinagar (J&amp;K) - Report attached as Annexure A</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">53.</p></td><td width="132" valign="top"><p class="TableParagraph">Petop-40</p></td><td width="66" valign="top"><p class="TableParagraph">PTP- 119</p></td><td width="95" valign="top"><p class="TableParagraph">Aug-24</p></td><td width="76" valign="top"><p class="TableParagraph">Jan-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mfg By: Ocean Organics Pvt Ltd P.O Khanna Nagar Amritsar -143001</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not conform to the IP 2022 requirement with respect to</p><p class="TableParagraph">Dissolution Test</p></td><td width="189" valign="top"><p class="TableParagraph">Drug Testing Laboratory Srinagar (J&amp;K) - Report attached as Annexure B</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">54.</p></td><td width="132" valign="top"><p class="TableParagraph">Pantobac-40</p></td><td width="66" valign="top"><p class="TableParagraph">MT2408 61</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Aug-26</p></td><td width="238" valign="top"><p class="TableParagraph">Mancare Laboratories Pvt Ltd Plot No. 11, Pharmacity Selaqui Dehradun , Uttarakhand 248011 Mrk By: NAVA Healthcare Pvt Ltd</p><p class="TableParagraph">C1/10 Lal Sai Marg Janakpuri New Delhi - 110058</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not conform to the IP requirements w,r,t Dissolution test</p></td><td width="189" valign="top"><p class="TableParagraph">Drug Testing Laboratory Srinagar (J&amp;K) - Report attached as Annexure C</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">55.</p></td><td width="132" valign="top"><p class="TableParagraph">Aticold</p></td><td width="66" valign="top"><p class="TableParagraph">TG24- 1268</p></td><td width="95" valign="top"><p class="TableParagraph">Jun-24</p></td><td width="76" valign="top"><p class="TableParagraph">May-26</p></td><td width="238" valign="top"><p class="TableParagraph">Athens Lifesciences Mauza Rampur Jattan Nahan Road Kala Amb Distt. Sirmour H.P 173030</p><p class="TableParagraph">Mfg For : Telethon Healthcare SCF 236 Second Floor Sector 13 Manimajra Chandigarh UT</p></td><td width="178" valign="top"><p class="TableParagraph">The sample does not conform to the IP 2022 requirement w.r.t Uniformity of weight &amp; Disintegration Test</p></td><td width="189" valign="top"><p class="TableParagraph">Combined Food &amp; Drug Testing Laboratory Jammu (J&amp;K) - Report attached as Annexure D</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">56.</p></td><td width="132" valign="top"><p class="TableParagraph">Calagy ( Calamine Lotion I.P.)</p></td><td width="66" valign="top"><p class="TableParagraph">SPA243 098</p></td><td width="95" valign="top"><p class="TableParagraph">Oct-24</p></td><td width="76" valign="top"><p class="TableParagraph">Sep-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s Skymap Pharmaceuticals Pvt. Ltd, Roorkee</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to clain as per I.P. 2022</p><p class="TableParagraph">w.r.t. assay of Zinc Oxide</p></td><td width="189" valign="top"><p class="TableParagraph">State lab</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">57.</p></td><td width="132" valign="top"><p class="TableParagraph">Deflazacort 6 mg Tablets</p></td><td width="66" valign="top"><p class="TableParagraph">CPT- 241518</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s Catasta Pharmaceuticals, Plot No. 113, DIC, Ind. Area, Baddi, Distt. Solan HP</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to clain as per Patent &amp; Proprietary in respect to</p><p class="TableParagraph">the Assay of Deflazacort.</p></td><td width="189" valign="top"><p class="TableParagraph">DTL BADDI</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">58.</p></td><td width="132" valign="top"><p class="TableParagraph">Diclofenac Potassium &amp; Paracetamol Tablets</p></td><td width="66" valign="top"><p class="TableParagraph">CPT- 241506</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s Catasta Pharmaceuticals, Plot No. 113, DIC, Ind. Area, Baddi, Distt. Solan HP</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to clain as per Patent &amp; Proprietary in respect to</p><p class="TableParagraph">the Assay of Diclofenac Pottassium</p></td><td width="189" valign="top"><p class="TableParagraph">DTL BADDI</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">59.</p></td><td width="132" valign="top"><p class="TableParagraph">Etoricoxib &amp; Thiocolchicoside Soft gel Capsules (Sancap)</p></td><td width="66" valign="top"><p class="TableParagraph">CD- 242077</p></td><td width="95" valign="top"><p class="TableParagraph">Dec-24</p></td><td width="76" valign="top"><p class="TableParagraph">Nov-26</p></td><td width="238" valign="top"><p class="TableParagraph">M/s Capsoft Healthcare Pvt Ltd, Shed no 6, khasra no 760-761, khaslsa complex, Vill Karuana, Sai Road Baddi, Distt. Solan H.P.</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to clain as per Patent &amp; Proprietary in respect to the Assay of Etoricoxib &amp;</p><p class="TableParagraph">Thiocolchicoside</p></td><td width="189" valign="top"><p class="TableParagraph">DTL BADDI</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">60.</p></td><td width="132" valign="top"><p class="TableParagraph">Sucralfate USP</p></td><td width="66" valign="top"><p class="TableParagraph">LSU240 9105</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">Aug-24</p></td><td width="238" valign="top"><p class="TableParagraph">Legend Industries at unit-II Plot no C1/200-201/4 Phase-II, opp. Encore Ltd. Naroda GIDC Ahmedabad</p><p class="TableParagraph">382330</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to U.S.P respect to identification and Assay of</p><p class="TableParagraph">Sucralfate.</p></td><td width="189" valign="top"><p class="TableParagraph">CDL Kolkata</p></td></tr><tr><td width="73" valign="top"><p class="TableParagraph">61.</p></td><td width="132" valign="top"><p class="TableParagraph">Sucralfate USP</p></td><td width="66" valign="top"><p class="TableParagraph">LSU240 9106</p></td><td width="95" valign="top"><p class="TableParagraph">Sep-24</p></td><td width="76" valign="top"><p class="TableParagraph">08/2025</p></td><td width="238" valign="top"><p class="TableParagraph">Legend Industries at unit-II Plot no C1/200-201/4 Phase-II, opp. Encore Ltd. Naroda GIDC Ahmedabad 382331</p></td><td width="178" valign="top"><p class="TableParagraph">Sample does not conforms to U.S.P respect to identification and Assay of Sucralfate.</p></td><td width="189" valign="top"><p class="TableParagraph">CDL Kolkata</p></td></tr></tbody></table><div style="text-align: justify;"></div></div></div><p style="text-align: justify; ">Also Read:<a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/drug-alert-70-drug-samples-fail-to-clear-cdsco-test-1-declared-spurious-147190">Drug Alert: 70 Drug Samples Fail To Clear CDSCO Test, 1 Declared spurious</a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><p style="text-align: justify; ">To view the official notice, click the link below:</p><div class="hocal-draggable" style="text-align: justify; " draggable="true"><a href="https://medicaldialogues.in/pdf_upload/stat2025-284675.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/stat2025-284675.pdf</a></div></div>

392. Himachal Pradesh hikes doctor stipends to tackle specialist shortage

     Tue, 29 Apr 2025 12:30:32 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284930-mdtv-2025-04-29t170134477.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">In a major move to address the shortage of medical specialists in the state, the Himachal Pradesh government has announced a stipend hike for doctors, ranging from 50% to 170%. Senior residents and tutor specialists will now receive Rs 1 lakh per month, up from the earlier Rs 60,000– Rs 65,000, while super specialists’ stipends have been raised to Rs 1.30 lakh.</p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">The decision aims to make government service more appealing to skilled medical professionals and fill the 376 vacant specialist posts across the state's medical colleges. The government also announced that doctors on study leave would continue to draw full pay, further incentivising retention and career growth.</p></div></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/health/doctors/senior-residents-to-now-get-rs-1-lakh-super-specialists-rs-13-lakh-stipend-hike-for-himachal-doctors-147403"><b>Senior Residents to now get Rs 1 Lakh, Super Specialists Rs 1.3 Lakh- Stipend Hike for Himachal Doctors</b></a></i></div></div></div>

393. 25-year-old FMGE aspirant dies of burn injuries in Hisar; Family alleges murder

     Tue, 29 Apr 2025 12:30:18 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284924-mdtv-2025-04-29t164843664.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">In a shocking and tragic incident, an Alwar-based 25-year-old Foreign Medical Graduate died with severe <a href="https://medicaldialogues.in/topics/burn%C2%A0injuries">burn injuries</a>. While it is still unclear how the doctor got the injuries, the Rajasthan police have registered a murder case against a man from Rewari.</p><p style="text-align: justify;">The doctor, who completed her medical degree from the Philippines and was preparing for the <a href="https://medicaldialogues.in/topics/Foreign%20Medical%20Graduate%20Examination">Foreign Medical Graduates Examination</a> (FMGE), was supposed to be in Delhi for her education. However, she was mysteriously found in Haryana's Hisar with severe burn injuries.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/health/doctors/stabbed-set-on-fire-25-year-old-doctor-preparing-for-fmge-dies-police-register-murder-case-147400"><b>Stabbed, Set on Fire? 25-year-old Doctor preparing for FMGE dies, Police register murder case</b></a></i></div><div></div></div><div class="pasted-from-word-wrapper"></div></div>

394. Doctors demand single-shift NEET PG 2025: "One Nation, One Shift" gains momentum

     Tue, 29 Apr 2025 12:15:38 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284928-mdtv-2025-04-29t165652412.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Demands for a single-shift NEET PG 2025 are escalating further, as doctors push for "One Nation, One Shift" to ensure fairness and transparency.</p><p style="text-align: justify;">Pointing out that the NEET UG entrance examination is held for 25 lakh students, who appear in one exam in a single shift, RTI activist Dr. Vivek Pandey has questioned why the same is not possible for the NEET Postgraduate exam as well.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/education/one-nation-one-shift-doctors-demand-for-single-shift-neet-pg-2025-intensifies-147415#:~:text=New%20Delhi%3A%20Demands%20for%20a,single%20shift%2C%20RTI%20activist%20Dr."><b>One Nation, One Shift! Doctors' Demand for Single-Shift NEET PG 2025 Intensifies</b></a></i></div><div><i></i></div></div><div class="pasted-from-word-wrapper"></div></div>

395. NMC Allows Delhi Medical Council to Relax Stipend Condition, give internship posting to FMGs at MCD Hospitals

     Tue, 29 Apr 2025 12:13:30 -0000

     <img src='https://medicaldialogues.in/h-upload/2022/08/31/184735-fmg-internship.webp' /><p style="text-align: justify; "><b>New Delhi:</b>&nbsp;Taking cognisance of the difficulties faced by the <a href="https://medicaldialogues.in/topics/Foreign-medical-graduates">Foreign Medical Graduates </a>(FMGs) to complete their one-year compulsory rotating internship training in Delhi, the <a href="https://medicaldialogues.in/topics/NMC">National Medical Commission</a> (NMC) has agreed to Delhi Medical Council's proposal to relax the condition to pay stipend to medical graduates from abroad, who are willing to forgo the stipend.</p><p style="text-align: justify; ">Although, the Apex Medical Commission acknowledged that as per FMGL Regulations, 2021, grant of stipend to interns is a State matter and NMC only is a regulatory body, it decided to relax the stipend conditions while keeping in view the best interest of students and financial implication to provide stipend by the <a href="https://medicaldialogues.in/topics/municipal-corporations">Municipal Corporation of Delhi</a> (MCDs).</p><p style="text-align: justify; ">As per the rules, the medical graduates from abroad must undergo a one-year mandatory internship to be able to register and practice in India. Without its completion, the FMGs become ineligible to appear in postgraduate (PG) entrance tests and commence their medical practice.</p><p style="text-align: justify; ">While institutes like Maulana Azad Medical College (MAMC) and <a href="https://medicaldialogues.in/topics/vmmc-and-safdarjung-hospital">Vardhman Mahavir Medical College</a> (VMMC) have existing Preventive and Social Medicine (PSM) departments, where the FMGs can undergo their mandatory training, these facilities are not present at non-teaching facilities such as Deen Dayal Upadhyaya Hospital, Ganga Ram, and BLK Max Hospital.</p><p style="text-align: justify; ">Even though these institutes offer internships to FMGs, they lack the mandatory PSM departments. Therefore, the students at these institutes are required to complete a three-month internship at alternative facilities like MCD hospitals with community medicine facilities.</p><p style="text-align: justify; ">Medical Dialogues had earlier reported that FMGs were alleging that the MCD had not allocated existing positions to FMG students, citing financial and position constraints. Due to this, the FMGs could not get the required practical experience. Explaining the issue, an Executive Member of the Delhi Medical Council, Dr. Ashwini Dalmiya had mentioned that the issue emerged after the Supreme Court proceedings regarding the FMG internship compensation as the Apex Court had mandated equal treatment and stipends for the FMGs during the internship. Following this, MCD stopped offering internship positions, citing inability to provide stipends due to budget limitations.</p><p style="text-align: justify; ">Raising the issue, the <a href="https://medicaldialogues.in/topics/delhi-medical-council">Delhi Medical Council</a> had written to the NMC. Now, the <a href="https://medicaldialogues.in/topics/undergraduate-medical-education-board">Undergraduate Medical Education Board</a> (UGMEB) of the apex Medical Commission has responded and agreed to relax the conditions for paying stipend to the FMGs if they forgo the stipend.</p><div contenteditable="false" data-width="523" style="left:NaN%;width:50%" class="image-and-caption-wrapper clearfix hocalwire-draggable float-none"><img src="https://medicaldialogues.in/h-upload/2025/04/29/284927-image-29-04-25-at-452-pm.webp" draggable="true" class="hocalwire-draggable float-none" data-float-none="true" data-uid="23690mWfPledLyFVXyu93ZOlZ4K0YElmK6fUw5771080" data-watermark="false" style="width: 100%;" info-selector="#info_item_1745925771736"><div class="inside_editor_caption image_caption hocalwire-draggable float-none" id="info_item_1745925771736"><br></div></div><p>Writing to the President of DMC on 28.04.2025, the UGMEB mentioned, <i>"The proposal of Delhi Medical Council to relax the condition to pay stipend to FMGs who are willing to forgo the stipend in Delhi, has been examined in National Medical Commission."</i></p><p><i>"As per FMGL Regulations, 2021, grant of stipend to interns is a State matter and NMC is only a regulatory body. However, keeping in view the best interests of students, and financial implication to provide stipend by Municipal Corporation of Delhi; the National Medical Commission has no objection to the proposal of Delhi Medical Council to relax the condition to pay stipend to FMGs who are willing to forgo the stipend,"</i> clarified NMC, while agreeing to DMC's proposal to relax the condition of paying stipend to FMGs.</p><p><i>"This is in view of the urgency involved &amp; to facilitate completion of their mandatory internship training, without further delay," </i>NMC UG Board further mentioned in the communication.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/delhi-fmgs-unable-to-enrol-for-internships-at-mcd-hospitals-147136" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: Delhi FMGs Unable to Enrol for Internships at MCD Hospitals</i></b></a></p>

396. Health Bulletin 29/ April/ 2025

     Tue, 29 Apr 2025 12:08:06 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284908-health-bulletin-2025-04-29t152211208.webp' /><p style="text-align: justify; "><b>Here are the top health news for the day:</b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Madras HC grants relief to doctor whose&nbsp;</b><span style="background-color: rgb(249, 249, 249);"><b>MD degree withheld over incomplete bond service</b></span></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">Noting that a posting was not issued within the two-year bond period, the Madras High Court bench recently granted relief to a doctor, whose Post Graduate Degree Certificate was retained by Madras Medical College due to the incomplete bond service liability.</p><p style="text-align: justify;">The HC bench comprising Justice N Mala directed the Dean of Madras Medical College to return the Post Graduate Degree Certificate in MD General Medicine to the petitioner within four weeks.</p></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/news/health/doctors/hc-relief-to-doctor-whose-md-medicine-degree-certificate-withheld-due-to-incomplete-bond-service-147424#:~:text=Earlier%2C%20reiterating%20that%20the%20bond,withheld%20by%20the%20institute%20on">HC comes to rescue of doctor whose MD Medicine degree certificate withheld due to incomplete bond service</a></i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>25-year-old FMGE aspirant dies of burn injuries in Hisar; Family alleges murder</b></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">In a shocking and tragic incident, an Alwar-based 25-year-old Foreign Medical Graduate died with severe <a href="https://medicaldialogues.in/topics/burn%C2%A0injuries">burn injuries</a>. While it is still unclear how the doctor got the injuries, the Rajasthan police have registered a murder case against a man from Rewari.</p><p style="text-align: justify;">The doctor, who completed her medical degree from the Philippines and was preparing for the <a href="https://medicaldialogues.in/topics/Foreign%20Medical%20Graduate%20Examination">Foreign Medical Graduates Examination</a> (FMGE), was supposed to be in Delhi for her education. However, she was mysteriously found in Haryana's Hisar with severe burn injuries.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/news/health/doctors/stabbed-set-on-fire-25-year-old-doctor-preparing-for-fmge-dies-police-register-murder-case-147400">Stabbed, Set on Fire? 25-year-old Doctor preparing for FMGE dies, Police register murder case</a></i></b></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Doctors demand single-shift NEET PG 2025: "One Nation, One Shift" gains momentum</b></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">Demands for a single-shift NEET PG 2025 are escalating further, as doctors push for "One Nation, One Shift" to ensure fairness and transparency.</p><p style="text-align: justify;">Pointing out that the NEET UG entrance examination is held for 25 lakh students, who appear in one exam in a single shift, RTI activist Dr. Vivek Pandey has questioned why the same is not possible for the NEET Postgraduate exam as well.</p></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><b><a href="https://medicaldialogues.in/news/education/one-nation-one-shift-doctors-demand-for-single-shift-neet-pg-2025-intensifies-147415#:~:text=New%20Delhi%3A%20Demands%20for%20a,single%20shift%2C%20RTI%20activist%20Dr.">One Nation, One Shift! Doctors' Demand for Single-Shift NEET PG 2025 Intensifies</a></b></i></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Himachal Pradesh hikes doctor stipends to tackle specialist shortage</b></div></div><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">In a major move to address the shortage of medical specialists in the state, the Himachal Pradesh government has announced a stipend hike for doctors, ranging from 50% to 170%. Senior residents and tutor specialists will now receive Rs 1 lakh per month, up from the earlier Rs 60,000– Rs 65,000, while super specialists’ stipends have been raised to Rs 1.30 lakh.</p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify;">The decision aims to make government service more appealing to skilled medical professionals and fill the 376 vacant specialist posts across the state's medical colleges. The government also announced that doctors on study leave would continue to draw full pay, further incentivising retention and career growth.</p></div></div><div class="pasted-from-word-wrapper"><div><p style="text-align: justify;"><b><i>For more information, click on the link below:</i></b></p></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b><i><a href="https://medicaldialogues.in/news/health/doctors/senior-residents-to-now-get-rs-1-lakh-super-specialists-rs-13-lakh-stipend-hike-for-himachal-doctors-147403">Senior Residents to now get Rs 1 Lakh, Super Specialists Rs 1.3 Lakh- Stipend Hike for Himachal Doctors</a></i></b></div><div></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><i><b><a href="https://medicaldialogues.in/news/education/one-nation-one-shift-doctors-demand-for-single-shift-neet-pg-2025-intensifies-147415#:~:text=New%20Delhi%3A%20Demands%20for%20a,single%20shift%2C%20RTI%20activist%20Dr."></a></b></i></div><div></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><b><i><a href="https://medicaldialogues.in/news/health/doctors/stabbed-set-on-fire-25-year-old-doctor-preparing-for-fmge-dies-police-register-murder-case-147400"></a></i></b></div><div></div></div><div class="pasted-from-word-wrapper"><div></div><div></div></div><div class="pasted-from-word-wrapper"><div><b><i><a href="https://medicaldialogues.in/news/health/doctors/hc-relief-to-doctor-whose-md-medicine-degree-certificate-withheld-due-to-incomplete-bond-service-147424#:~:text=Earlier%2C%20reiterating%20that%20the%20bond,withheld%20by%20the%20institute%20on"></a></i></b></div><div></div></div>

397. Madras HC grants relief to doctor whose MD degree withheld over incomplete bond service

     Tue, 29 Apr 2025 12:00:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284922-mdtv-2025-04-29t164543626.webp' /><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Noting that a posting was not issued within the two-year bond period, the Madras High Court bench recently granted relief to a doctor, whose Post Graduate Degree Certificate was retained by Madras Medical College due to the incomplete bond service liability.</p><p style="text-align: justify;">The HC bench comprising Justice N Mala directed the Dean of Madras Medical College to return the Post Graduate Degree Certificate in MD General Medicine to the petitioner within four weeks.</p></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><b>For more information, click on the link below:</b></i></div></div><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><i><a href="https://medicaldialogues.in/news/health/doctors/hc-relief-to-doctor-whose-md-medicine-degree-certificate-withheld-due-to-incomplete-bond-service-147424#:~:text=Earlier%2C%20reiterating%20that%20the%20bond,withheld%20by%20the%20institute%20on"><b>HC comes to rescue of doctor whose MD Medicine degree certificate withheld due to incomplete bond service</b></a></i></div><div></div></div><div class="pasted-from-word-wrapper"></div></div>

398. Ayushman Vay Vandana: Delhi launches Rs 10 lakh health cover for Senior Citizens

     Tue, 29 Apr 2025 11:45:53 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284892-delhi-government-launches-ayushman-vay-vandana-scheme.webp' /><p><b>New Delhi: </b>A boon for senior citizens, the <a href="https://medicaldialogues.in/state-news/delhi">Delhi </a>government has officially launched the Ayushman Vay Vandana Scheme, offering comprehensive health insurance coverage of up to Rs 10 lakh annually to all senior citizens aged 70 years and above.&nbsp;</p><p>Chief Minister Rekha Gupta, in collaboration with Union Minister Hardeep Singh Puri, formally inaugurated the scheme at a launch event in the capital. The first batch of Vay Vandana health cards was distributed to senior citizens, marking the rollout of this ambitious health initiative.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/ayush/ayurveda/news/25-lakh-elderly-enrolled-for-ayushman-vay-vandana-cards-health-ministry-139586" style="background-color: rgb(255, 255, 255);"><b>Also Read: 25 lakh elderly enrolled for Ayushman Vay Vandana cards: Health Ministry</b></a></p><p>Medical Dialogues had previously reported that in a significant achievement, the enrollment for the Ayushman Vay Vandana Card has reached an impressive milestone of 25 lakh in a span of less than 2 months of its launch by the Prime Minister on 29 October, 2024.</p><p>The health coverage is a collaboration between the central government’s Ayushman Bharat Pradhan Mantri Jan Arogya Yojana (AB PM-JAY) and a matching contribution by the Delhi government. Under the scheme, eligible senior citizens will receive ₹5 lakh from AB PM-JAY and an additional ₹5 lakh from the state. </p><p>According to a PTI news report, under this scheme, yearly medical assistance worth Rs 5 lakh will be provided free of cost. Additionally, Rs 5 lakh coverage will be provided under the Delhi government's scheme, making the total health cover Rs 10 lakh. </p><p>A key feature of the Vay Vandana Yojana is the issuance of unique digital health cards to all registered beneficiaries. These cards will securely store individuals' complete medical records, including regular health check-up data and emergency service details, ensuring seamless and efficient access to medical care. </p><p>Under this initiative, all medical tests for residents aged 70 and above in Delhi will be provided entirely free of charge. Gupta earlier posted on X, "Serving the elderly is our top priority. Now, the Centre and Delhi governments together are providing health coverage of up to Rs 10 lakh to senior citizens aged 70 and above. Secure the health of your loved ones - get the Ayushman Vaya Vandana Card today,” reports PTI.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/ayushman-bharat-scheme-a-boon-for-the-poor-says-pm-modi-during-varanasi-visit-146496"><b>Also Read: Ayushman Bharat scheme- A boon for the poor, says PM Modi during Varanasi Visit</b></a></p><div class="pasted-from-word-wrapper"><div><span style="background-color: rgb(249, 249, 249);">Speaking to </span><a href="https://www.business-standard.com/health/world-day-safety-health-at-work-2025-ai-digitalisation-ilo-report-125042800339_1.html" rel="nofollow">Business Standard</a><span style="background-color: rgb(249, 249, 249);">, Rekha Gupta said, “Every person who is above 70 years of age will get the benefit of this scheme. Only two things are required: first, you should be a resident of Delhi, and second, you should have an Aadhaar card. Registration starts today, and once your card is made, you will be able to get treatment in hospitals registered under this scheme, both in Delhi and across the country. Congratulations to all of you for this scheme.”</span></div></div><p>More than 100 hospitals in Delhi have already joined the scheme, and over 30,000 individuals have registered for cashless treatment services. </p><p>Health Minister Pankaj Singh described the scheme as a "historic step" in strengthening the capital’s healthcare system. According to Business Standard, this scheme is portable, and any Delhi resident, even if they are outside the city, can enrol. Chemotherapy, ICU care, surgeries, and 961 other medical treatments are also included,” Singh said.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/pm-modi-hails-ayushman-bharat-as-a-lifeline-for-the-poor-during-varanasi-visit-146615"><b>Also Read: PM Modi hails Ayushman Bharat as a lifeline for the poor during Varanasi visit</b></a></p><div class="pasted-from-word-wrapper"><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div><p>Union Minister Hardeep Singh Puri echoed these sentiments, noting the scheme’s potential to serve as a model for equitable healthcare across India. He said that as more and more hospitals in Delhi get empanelled under the scheme, it will prove to be a model for others for years to come in terms of universal health access.</p></div>

399. FMGE June 2025 Registration Live: Fee, Payment guidelines Explained

     Tue, 29 Apr 2025 11:26:33 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284912-fees.webp' /><p style="text-align: justify; "><b>New Delhi- </b>The National Board of Examinations in Medical Sciences (NBEMS) has begun the Foreign Medical Graduates Examination (FMGE) June 2025 application process. The application portal will be open till 17th May 2025, 11:55 PM. Application forms once submitted cannot be withdrawn.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">Meanwhile, while submitting the application form, candidates have to pay a total of Rs 6,195, out of which Rs 5,250 is the examination fee and Rs 945 is GST @ 18%. Fee shall neither be carried forward to a future date nor refunded under any circumstances. Any claim for refund, adjustment or carrying forward of the application fee will not be entertained.</p><p dir="ltr" style="text-align: justify; ">In this regard, NBEMS has released the information bulletin detailing the examination fee process for candidates willing to appear for the FMGE June 2025.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/fmge-june-2025-check-out-key-dates-how-to-apply-147420"><b>Also Read:&nbsp;</b>FMGE June 2025: Check out Key dates, how to apply!</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u>HOW TO PAY</u></b></p><p dir="ltr" style="text-align: justify; ">The prescribed exam fee should be remitted through the payment gateway provided using a UPI, Credit Card or a Debit Card issued by banks in India or other modes as may be made available and have been provided on the web page. The fee cannot be deposited through any mode other than the payment gateway available while submitting the online application form.</p><p dir="ltr" style="text-align: justify; ">As per the information bulletin, candidates must ensure that the payment made for the examination fee is successful and confirmation of the same can be seen in the application form under payment status reflected as “S” (for successful). In case the status is shown as pending, the payment might be stuck with your bank and might be cleared at a later date. The application submission process is not completed till such time the status of payment is reflected as “S” in the application form. NBEMS shall not be responsible for the rejection of your application due to a delay in the settlement of the payment by your bank to NBEMS. </p><p dir="ltr" style="text-align: justify; ">Meanwhile, it is at the discretion of the applicant to make another payment for completing the application submission process. In the event of receipt of duplicate/multiple examination fees towards the same application ID, NBEMS shall refund the excess fees received for an application, retaining the prescribed examination fee, after closure of the application window. </p><p dir="ltr" style="text-align: justify; ">Examination fees in respect of candidates who are absent or have been declared ineligible for any reason shall be forfeited. Candidates are advised to read the screening test regulations and the information bulletin for the FMGE June 2025 session carefully and satisfy the terms and conditions for the fulfilment of eligibility criteria before proceeding with the payment of fees.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/stabbed-set-on-fire-25-year-old-doctor-preparing-for-fmge-dies-police-register-murder-case-147400"><b>Also Read:&nbsp;</b>Stabbed, Set on Fire? 25-year-old Doctor preparing for FMGE dies, Police register murder case</a></div><div class="pasted-from-word-wrapper"><div></div></div>

400. After Last Year's Irregularities, Centre Tightens NEET 2025 Security Net

     Tue, 29 Apr 2025 11:12:22 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/24/284215-neet-ug-2025.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">New Delhi:&nbsp;</span>In a bid to ensure the smooth and secure conduct of NEET UG 2025, the Ministry of Education is holding a series of meetings with district magistrates (DMs) and superintendents of police (SPs) across all states and Union territories. The move comes as part of a comprehensive strategy to avoid any lapses during the exam, scheduled for May 4, in the wake of last year’s controversies involving paper leaks and irregularities.</p></div><div class="pasted-from-word-wrapper"> <p data-start="525" data-end="864" class="">The medical entrance exam, which over 23 lakh candidates are expected to take this year, will be held in more than 550 cities at over 5,000 centres nationwide. Officials have activated district-level coordination committees and rolled out multi-layered security measures, aiming to make the exam process "fool-proof"</p></div><div class="pasted-from-word-wrapper"><p>Sources informed PTI, "<span style="text-align: justify;">The Ministry of Education is holding a series of meetings with district magistrates and superintendents of police from all states and Union territories to ensure there are no lapses in the upcoming medical entrance exam </span><a href="https://medicaldialogues.in/topics/neet-ug" target="_blank" style="text-align: justify; background-color: rgb(249, 249, 249);">NEET UG</a><span style="text-align: justify;">."</span></p><p style="text-align: justify; ">The May 4 exam will be conducted in more than 550 cities at over 5,000 centres across the country.&nbsp; The ministry has been working on a “fool-proof” plan after the last year’s exam was blistered by irregularities, including paper leaks.</p><p style="text-align: justify;">“To ensure smooth, fair and secure conduct of <a href="https://medicaldialogues.in/topics/neet-ug" target="_blank">NEET UG</a>, a series of meetings have been held with DMs and SPs of all states and UTs. The district-level coordination committees are being fully activated to manage logistics, security and crisis response,” a source told PTI.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-nta-launches-portal-to-report-suspicious-claims-warns-candidates-147397"><b>Also Read:NEET 2025: NTA launches portal to report suspicious claims, warns candidates</b></a></p><p style="text-align: justify;">“There will be multi-layered frisking by district police in addition to <a href="https://medicaldialogues.in/topics/nta" target="_blank">NTA</a>-designated security at the centres. The transport of confidential materials like question papers and OMR sheets will be under full police escort. Coaching centres and digital platforms will be monitored to prevent organised cheating networks,” the source added.</p><p style="text-align: justify;">Duty Magistrates are being deployed for mandatory inspection of all examination centres, while there will be personal visits by DMs and SPs to exam centres to assess preparedness.</p><p style="text-align: justify;">Under scrutiny over last year’s irregularities in <a href="https://medicaldialogues.in/topics/neet-ug" target="_blank">NEET UG </a>and PhD entrance NET, the Centre had last year set up a panel to ensure “transparent, smooth and fair” conduct of exams by the National Testing Agency, or <a href="https://medicaldialogues.in/topics/nta" target="_blank">NTA</a>.</p><p style="text-align: justify;">Last year, the UGC-NET (University Grants Commission – National Eligibility Test) was cancelled as the ministry received input that its integrity had been compromised.</p><p style="text-align: justify;">Both matters are being investigated by the Central Bureau of Investigation (CBI).</p><p style="text-align: justify;">Two other exams — CSIR-UGC NET, NEET-PG — were cancelled at the last moment as a preemptive step.</p><p style="text-align: justify;">This year, more than 23 lakh candidates are expected to appear for the exam which determines whether they will it to a medical college in the country.</p><p style="text-align: justify;">“Monitored by the education ministry, 180 central institutions have been entrusted to verify the preparedness of the centres. The Ministry is closely working with the Home Ministry which also conducted meetings with state chief secretaries and DGPs to take stock of the ground situation,” the source said.</p><p style="text-align: justify;">The NTA had on Saturday a opened a platform to report suspicious claims regarding NEET-UG.</p><p style="text-align: justify;">“Candidates can report any suspicious activities falling in three categories — unauthorised websites or social media accounts claiming access to NEET question paper; individuals claiming access to exam content and impersonators posing as NTA or government officials,” NTA Director General Pradeep Singh Kharola said.</p><p style="text-align: justify;">“The reporting form is simple and allows users to describe what they observed, where and when it occurred and upload supporting file. The initiative aligns with the Public Examinations (Prevention of Unfair Means) Act, 2024 which aims to eliminate unfair practices in public examinations and protect the future of aspirants,” he said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-2025-nta-notifies-advance-intimation-of-exam-city-for-candidates-147214"><b>Also Read:NEET 2025: NTA notifies Advance Intimation of Exam City for candidates</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

401. AIIMS Jammu opens Centre for advanced genomics, precision medicine

     Tue, 29 Apr 2025 10:55:07 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284859-aiims-jammu-4.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Jammu: The All India Institute of Medical Sciences (AIIMS) Jammu on Monday inaugurated the&nbsp;</span>Centre for Advanced Genomics and Precision Medicine. This facility is set to enhance affordable, precision-driven cancer care using advanced Next Generation Sequencing (NGS) technology.</p><p style="text-align: justify; ">According to an IANS report, the Centre, developed in collaboration with oncology company 4baseCare, is equipped with the Illumina NextSeq 2000 sequencing machine, offering comprehensive genomic profiling for cancer patients.</p><p style="text-align: justify;">The powerful technology enables clinicians to design highly personalised, targeted treatment plans tailored to each patient’s unique molecular profile. <a href="https://medicaldialogues.in/topics/aiims-jammu" target="_blank">AIIMS Jammu</a> announced its collaboration with 4baseCare in January.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/jammu-aiims-pioneers-advanced-jaw-surgery-procedures-145512"><b>Also Read:Jammu AIIMS Pioneers Advanced Jaw Surgery Procedures</b></a></p><p style="text-align: justify;">“For every patient we treat, we are treating a mother, a father, a sister, or a brother. This partnership is our promise to every family who walks through our doors that we will do everything in our power to bring them the care they deserve,” Prof (Dr) Shakti Kumar Gupta, Executive Director and CEO, <a href="https://medicaldialogues.in/topics/aiims-jammu" target="_blank">AIIMS Jammu</a>.</p><p style="text-align: justify;">“Traditionally, access to such advanced genomic testing has been prohibitively expensive for many patients. However, with this initiative, high-quality NGS-based tests will now be made available at affordable costs, paving the way for greater inclusivity in precision oncology across India.</p><p style="text-align: justify;">Further solidifying its role as a national referral hub, the Centre will accept samples from patients and healthcare providers across the country, ensuring that cutting-edge molecular diagnostics are accessible, regardless of geographical barriers, reports IANS.</p><p style="text-align: justify;">The Centre will focus on targeted, biomarker-driven therapies, enabling personalised treatment plans to improve outcomes and quality of life of cancer patients.</p><p style="text-align: justify;">Using genomics, the facility also aims to tackle rare diseases. And to boost healthier pregnancies, the centre will integrate cutting-edge genetic technologies such as Non-Invasive Prenatal Testing (NIPT), Preimplantation Genetic Screening (PGS), and Preimplantation Genetic Diagnosis (PGD).</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/aiims-jammu-triggers-security-alert-after-suspected-drone-discovery-145372"><b>Also Read:AIIMS Jammu Triggers Security Alert After Suspected Drone Discovery</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

402. CDSCO panel grants clearance to Morepen Labs to conduct BE studies for fatty liver disease drug Resmetirom

     Tue, 29 Apr 2025 10:41:31 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/06/07/240445-cdsco-approval-3.webp' /><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"><b>Gurugram</b>:&nbsp;</span><span style="background-color: rgb(255, 255, 255);"><a href="https://medicaldialogues.in/topics/Morepen-labs">Morepen Laboratories Ltd. </a>has received clearance from the Subject Expert Committee (SEC) of Central Drugs Standard Control Organization (<a href="https://medicaldialogues.in/topics/CDSCO">CDSCO</a>) to conduct Bioequivalence (‘BE’) studies for Resmetirom 60 mg, 80 mg and 100 mg tablets as per the protocol submitted.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">This will be followed by clinical trials as per approved protocols.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> Resmetirom is a highly promising therapy under development for non-alcoholic steatohepatitis (‘NASH’), a serious form of <a href="https://medicaldialogues.in/topics/non-alcoholic-fatty-liver-disease">non-alcoholic fatty liver disease</a> (‘NAFLD’) characterized by inflammation, liver damage, and fat accumulation in the liver, potentially leading to scarring (fibrosis), cirrhosis, and even liver cancer. It is often associated with obesity, metabolic syndrome, and type 2 diabetes, and while it can be a silent disease in the early stages, it can progress to severe liver damage if left untreated. </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">“This is a critical step forward in our journey to bring a much-needed innovation to the hepatology market,” said Sanjay Suri, Executive Director, Morepen Laboratories. </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">“We are proud to be one of the first few Indian companies gearing up to launch the finished formulation of Resmetirom. Our endto-end integration – from APIs to finished dosage – gives us a unique edge in speed, quality, and scalability.” </span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">"As one of the first Indian companies to foray into this therapeutic area, Morepen is strategically positioned to serve both domestic and international markets and is also evaluating out-licencing opportunities with potential marketing partners," the Company said.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"> NASH, a progressive liver disease that affects over 115 million people worldwide. According to industry estimates, the global NASH treatment market is projected to grow from USD 2.5 billion in 2024 to over USD 16 billion by 2032, driven by increasing prevalence, clinical awareness, and regulatory approvals.</span></p><div class="pasted-from-word-wrapper"><div>Morepen has a global footprint, exporting its APIs and formulations to over 80 countries, including regulated markets such as the U.S., Europe, and Japan. The company’s API manufacturing facilities are USFDA, EU-GMP, and WHO-GMP compliant.&nbsp;</div></div>

403. Dr M Raja Rao takes charge as Principal of Osmania Medical College

     Tue, 29 Apr 2025 10:30:47 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284909-untitled-design-25.webp' /><p style="text-align: justify; "><b>Hyderabad:</b>&nbsp;Dr M Raja Rao has been officially appointed as the new in-charge Principal of <a href="https://medicaldialogues.in/topics/osmania-medical-college" target="_blank">Osmania Medical College </a>(OMC), Hyderabad.<br></p><p style="text-align: justify; ">Before taking on his new responsibilities at OMC, Dr. Rao was the principal of Government Medical College (GMC), Yadadri Bhongir. He was appointed to that role in July 2024 during a large-scale reshuffle in the state’s Health Department.&nbsp;</p><p style="text-align: justify; ">Earlier, Dr. Rao had also served as the Superintendent of Gandhi Hospital, where he played a key role during the challenging days of the COVID-19 pandemic, starting in April 2020.</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/news/health/hospital-diagnostics/lux-hospitals-launches-endoanal-real-time-ultrasound-guided-laser-procedure-for-fistula-in-ano-141311" target="_blank"> LUX Hospitals Launches Endoanal Real-Time Ultrasound-Guided Laser Procedure for Fistula in Ano</a></b></p><p style="text-align: justify; ">Dr. Rao took over the position following a vacancy left by Dr. A. Narendra Kumar, who was promoted to the role of Director of Medical Education (DME) in January this year, <a href="https://www.thehindu.com/news/cities/Hyderabad/dr-raja-rao-appointed-in-charge-principal-of-osmania-medical-college/article69490787.ece" target="_blank" rel="nofollow">The Hindu</a> reports.&nbsp;</p><p style="text-align: justify; ">After joining the new role, Dr Rao said, <i>"It is my proud privilege to be the Principal of this esteemed institute, where dedication to excellence in medical education, research and patient care is our divine force. We take pride in a world-class faculty, state-of-the-art facilities and a rich academic environment that fosters a lifelong pursuit of learning."</i></p><p style="text-align: justify; ">Osmania Medical College is a Government Medical College in Hyderabad, Telangana, India. It was founded in 1846 by the 5th Nizam of Hyderabad and Berar, Afzal ud Dowla, Asaf Jah V. The college was originally affiliated to the Osmania University system; now it is affiliated to the Kaloji Narayana Rao University of Health Sciences and the Osmania General Hospital.</p><p style="text-align: justify; ">The college was ranked 48th among the medical colleges in India in 2024 by the National Institutional Ranking Framework (NIRF) and is also an ISO ISO-certified institute.</p><p style="text-align: justify; ">Medical Dialogues had previously reported that Health Minister C Damodar Raja Narasimha and Transport Minister Ponnam Prabhakar laid the foundation stone for a new girls' hostel at Osmania Medical College. This initiative is designed to improve facilities for female students at the college, marking a significant step toward better accommodation and support for the increasing number of women attending the prestigious institution.</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/hospital-diagnostics/osmania-medical-college-gets-new-girls-hostel-building-at-cost-of-rs-121-crore-134547" target="_blank">Osmania Medical College gets new girls' hostel building at cost of Rs 121 crore</a></b></p>

404. Appearing for NEET PG 2025! Know the complete Exam Scheme

     Tue, 29 Apr 2025 10:13:25 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/11/06/259619-neet-pg-scheme-of-exam.webp' /><p>New Delhi- The National Board of Examinations in Medical Sciences (<a href="http://medicaldialogues.in/topics/nbems" target="_blank">NBEMS</a>) is currently conducting the registration process for the National Eligibility and Entrance Test-Postgraduate (<a href="https://medicaldialogues.in/topics/neet-pg" target="_blank">NEET PG</a>) exam for the academic year 2025 PG medical admissions. The information bulletin has been released on the official website of NBEMS. All the interested candidates are advised to take note of the scheme of examination and other important details as mentioned below.<br></p><div class="pasted-from-word-wrapper"><div id="ATS_mid1"></div><div class="inside-post-ad-1 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_1"><div class="header-non-loggedin-ad"><div class="advert-panel"></div></div></div></div><p><b><u>Scheme of NEET-PG 2025 </u></b></p><p>NEET-PG 2025 shall be conducted on 15th June 2025 through computerbased examination in a single day. There will be Two examination shifts on 15th June 2025. Candidates will be allotted to one of the two shifts by NBEMS.</p><p>The candidates shall not be able to exercise the choice of shift (Morning or Afternoon) in which they shall be allowed to take the examination. The allotment of the shifts to the candidates will be done by NBEMS purely randomly.</p><p><b>Syllabus</b> : The syllabus for the exam shall comprise of subject/knowledge area as per Graduate Medical Education Regulations issued by the National Medical Commission/ the erstwhile Medical Council of India.</p><p>The examination shall be a multiple-choice questions based test delivered using computers network (CBT) as per scheme prescribed.</p><p>The exam comprises of 200 Multiple Choice Questions with each question having 4 response options/distractors in English language only. Candidates are required to select the correct/best/most appropriate response/answer out of the 4 response options provided in each question. Time allotted is 3 hrs 30 minutes.</p><p>Marking Scheme: Allocation of marks for each MCQ shall be as follows:</p><table class="table table-bordered"><tbody><tr><td>RESPONCE</td><td>MARKS</td></tr><tr><td>Correct Responce</td><td>4 Marks</td></tr><tr><td>Incorrect Responce</td><td>1 Mark Shall be deducted</td></tr><tr><td>Unattempted Question</td><td>Zero</td></tr></tbody></table><p>There shall be 25% negative marking for incorrect answers. No marks will be deducted for unattempted questions.</p><p>During the examination candidates are given an option to mark any question, whether attempted or not, for review which means that candidate has been given&nbsp; an option to go through these questions again before the examination time ends. Candidates may note that such questions which are marked for review shall be evaluated as per the marking scheme mentioned above.</p><p>The question paper for NEET-PG will be divided into five time bound sections, namely Group A, B, C, D &amp; E. The questions from subjects of MBBS curriculum shall be distributed across these five sections of 40 questions each. Each section will have 42 minutes of time allotted for the section. Candidates would be restricted to proceed to the next section till completion of the allotted time of the previous section and candidates would not be allowed to review the questions/ modify the responses of a section after the completion of the allotted time of that section. Questions of the next section will start automatically after the completion of the allotted time of the previous section.</p><p>*The actual number of such time-restricted sections may vary based on the total number of questions in the question paper and operational feasibility in making such sections.</p><p>&nbsp;Allocation of time for NEET-PG 2025 shall be as follows:</p><table class="table table-bordered"><tbody><tr><td>Activites</td><td><p>Shift-I Timings </p></td><td>Shift-II Timings</td></tr><tr><td><p>Allow Candidates to enter the examination centre and </p><p>Commence Registration for the test</p></td><td><p>07:00 AM</p></td><td><p>01:30 PM&nbsp;</p></td></tr><tr><td><p>Entry closes at Examination Center</p></td><td><p>08:30 AM</p></td><td><p>03:00 PM&nbsp;</p></td></tr><tr><td><p>Grant access for Candidate Login</p></td><td><p>08:45 AM&nbsp;</p></td><td><p>03:15 PM&nbsp;</p></td></tr><tr><td><p>Candidates log in to read instructions</p></td><td><p>08:50 AM&nbsp;</p></td><td><p>03:20 PM&nbsp;</p></td></tr><tr><td><p>Exam Start Time</p></td><td><p>09:00 AM</p></td><td><p>03:30 PM</p></td></tr><tr><td><p>Exam End Time</p></td><td><p>12:30 PM</p></td><td><p>07:00 PM&nbsp;</p></td></tr></tbody></table><p><b>Steps for a Computer Based Test&nbsp;&nbsp;</b></p><ul class="hocalwire-editor-list"><li>Submit Online Application Form</li><li>Edit Application in Edit Window, if required</li><li>Rectify Images in Final Edit Window, if asked</li><li>Watch Demo Test (At NBEMS Website)</li><li>Download Admit Card</li><li>Report at Test Centre on Schedule Date &amp;Time</li><li>Security Check-in Process</li><li>Registration for Test + Face ID &amp; Biometric Capture</li><li>Examination Begins</li><li>During Exam FaceID/Biometric Verification</li><li>&nbsp;Examination Ends</li></ul><p><u><b>SCHEDULE</b></u></p><div class="pasted-from-word-wrapper"><div class="article-text-desc entry-content clearfix single-post-content"><div id="post-content-inner" class="row post-content-inner"><div class="details-content-story"><div class="story"><div class="pasted-from-word-wrapper"><div class="pasted-from-word-wrapper"><div dir="ltr"><table><colgroup><col width="54"><col width="362"><col width="208"></colgroup><tbody><tr><td><p dir="ltr">S.NO</p></td><td><p dir="ltr">PROCESSES</p></td><td><p dir="ltr">TIMELINES</p></td></tr><tr><td><p dir="ltr">1</p></td><td><p dir="ltr">Online Submission of Application Form.</p></td><td><p dir="ltr">17th April 2025 (03:00 PM Onwards) to 07th May 2025 (Till 11:55 PM).</p></td></tr><tr><td><p dir="ltr">2</p></td><td><p dir="ltr">Edit Window for All Payment Success Applications (Any information/documents can be edited except Name, Nationality, Email, Mobile number and Test City).</p></td><td><p dir="ltr">09th May 2025 to 13th May 2025</p></td></tr><tr><td><p dir="ltr">3</p></td><td><p dir="ltr">Pre-Final Selective Edit Window to rectify Deficient/Incorrect Images</p><p dir="ltr">-Photograph</p><p dir="ltr">-Signatures</p><p dir="ltr">-Thumb Impression.</p></td><td><p dir="ltr">17th May 2025 to 21st May 2025</p></td></tr><tr><td><p dir="ltr">4</p></td><td><p dir="ltr">Final Selective Edit Window to rectify Deficient / Incorrect Images Photograph Signatures Thumb Impression (No further opportunity shall be given).</p></td><td><p dir="ltr">24th May 2025 to 26th May 2025</p></td></tr><tr><td><p dir="ltr">5</p></td><td><p dir="ltr">Informing the Test City to the candidates.</p></td><td><p dir="ltr">02nd June 2025</p></td></tr><tr><td><p dir="ltr">6</p></td><td><p dir="ltr">Issue of Admit Cards.</p></td><td><p dir="ltr">11th June 2025</p></td></tr><tr><td><p dir="ltr">7</p></td><td><p dir="ltr">Examination Date.</p></td><td><p dir="ltr">15th June 2025</p></td></tr><tr><td><p dir="ltr">8</p></td><td><p dir="ltr">Declaration of Result</p></td><td><p dir="ltr">By 15th July 2025</p></td></tr><tr><td><p dir="ltr">9</p></td><td><p dir="ltr">Cut-off date for completion of internship towards eligibility for NEET-PG 2025.</p></td><td><p dir="ltr">31st July 2025</p></td></tr></tbody></table></div></div><p><u><b>Information for Candidates</b></u></p><p>NEET-PG 2025 is the eligibility-ranking examination for admission to various MD/MS/PG Diploma courses of 2025-26 admission session. Admissions to Post MBBS DNB Courses, Post MBBS Direct 6 year DrNB courses and NBEMS diploma courses are also undertaken through NEETPG.</p><p>NEET-PG 2025 will be conducted by NBEMS. The role of NBEMS is limited to the conduct of NEET-PG, declaration of the result and handing over the result to the designated counseling authority. NBEMS has no role in counseling and allotment of PG seats. Verification of documents and eligibility determination of the candidates shall be undertaken at the time of counseling/admission process by the concerned authority.</p><p>Candidate may kindly note that appearance in NEET-PG does not confer any automatic rights to secure a Post graduate MD/MS/Post Graduate Diploma seat. The selection and admission to Postgraduate seats in any medical institutions recognized for running MD/ MS/Post Graduate Diploma courses as per the National Medical Commission (NMC) Act, 2019 and the Post Graduate Medical Education Regulations, 2023 is subject to fulfilling the admission criteria, eligibility, medical fitness and such criteria as may be prescribed by the respective universities, medical institutions, the NMC, State/Central Government.</p><p>Candidates are advised to read the Information Bulletin carefully and go through the instructions regarding submission of online application form given in the information bulletin as well as on NEET-PG 2025 index page on NBEMS website before starting online submission process for NEET-PG 2025 .</p><p>Candidates are deemed to have read, agreed and accepted the Information Bulletin and the terms and conditions in the Information Bulletin for NEET-PG 2025 on completing the online submission of application form.</p><p>Candidate should ensure that all the information entered during the online submission of application form is correct and factual. Information provided by the candidates in the online application form shall be treated as correct. The responsibility of correctness of information in the application form shall be of the concerned candidate. The option of editing certain information entered in the application form shall be available to the candidates during the edit window. NBEMS will not entertain, under any circumstances, any request for change in the information provided by the candidates after closure of the edit window. Please refer Chapter on Instructions to fill Application Form for details regarding Edit Window.</p><p>NBEMS itself does not edit /modify/alter any information entered by the candidates at the time of online submission of application form under any circumstances. There is no provision of accessing the application form to make any changes in the information provided in the application form after closure of edit window. Such requests to make any changes shall not be entertained. Candidates, however, shall be able to rectify the deficiencies in their application (if so communicated by NBEMS) regarding images uploaded, by the prescribed cut-off dates.</p><p>Please refer Chapter on Instructions to Fill NEET-PG Application Form. Candidates are advised to review their applications submitted and rectify the deficiencies, if found any, within the window as detailed below. Candidates may note that deficiency in the application form pertaining to images uploaded may be communicated to them by NBEMS, however, it shall be the sole responsibility of the applicant to ensure that the application submitted is complete in all aspects as per the information bulletin. If any deficiency in the application which was not communicated by NBEMS to the applicant before conduct of the examination, is noted at any later stage, this would not create any equity in favour of the candidate and confer any rights on to the candidates for grant of eligibility for the examination.</p><p>Edit Window: Candidates who have successfully submitted their payment for the application during Application Submission window shall only be allowed to edit their applications during 09th May 2025 to 13th May 2025. No new application can be registered or payment can be made during edit window. However, the balance fee required, if any, in case of change in candidate category and/or PwD status can be paid during the edit window. Any information/document can be changed/corrected during the edit window except for Name, Test City, Nationality, Mobile Number and Email ID. Information can be edited any number of times before the closure of the edit window. The last submitted information will be saved in records.</p><p>Final Edit Window: Deficiency related to images uploaded (photograph, Signature, Thumb Impression) shall be intimated to the concerned candidates and same can be corrected during the Pre-Final Selective edit window i.e. 17th May 2025 to 21st May 2025. A list of such applicants who would fail to rectify their images in the application form shall be published on NBEMS website and a FINAL Selective Edit window will be opened from 24th May 2025 to 26th May 2025 for them to enable them to rectify the images as per image upload guidelines. Applications of such candidates who would fail to rectify their images even during this FINAL edit window shall be rejected. No further opportunity shall be given to make corrections.</p><p>Candidates are advised to submit the images in their application as per prescribed image upload guidelines. Failure to submit images as per guidelines and/or failure to rectify the images shall invite rejection of the application.</p><p>Application for NEET-PG 2025 can only be submitted online through NBEMS website.</p><p>There is no other methodology for application submission. Application submitted through any other mode shall be summarily rejected.</p><p>A candidate can submit NEET-PG 2025 application form only once. If a candidate is found to have submitted more than one application form for NEET-PG 2025, NBEMS may issue admit card to the application bearing higher order Application number (application ID) and cancel other application(s) forfeiting the fee for them. In an event any unfair practice is detected by NBEMS at any stage of examination/admission process, NBEMS may cancel the candidature of such candidates and debar them from appearing in any examinations conducted by NBEMS as per provisions of the Unfair Means Guidelines.</p><p>Candidates who fail to submit duly completed applications with requisite documents and/or fail to rectify the deficiencies in their applications by the last date prescribed for rectification shall be declared ineligible. Admit Card shall not be issued to candidates who are declared ineligible before conduct of examination. In such cases, the entire fees will be forfeited.</p><p>Applications of candidates producing false or fabricated information/records will not be considered and such candidates will be further debarred from appearing in the future examinations of NBEMS. Action as deemed appropriate by NBEMS will be taken if false or fabricated records/ information is submitted or any unfair means are used.</p><p>Candidates are advised to ensure that the information provided is factual and supported with documents. Columns marked (*) in the application form are mandatory and can not be left blank. In the event of rejection of the application form, no correspondence/request for re-consideration will be entertained.</p><p>Candidates should ensure before applying for the examination that their MBBS degree is recognized as per provisions of the NMC Act, 2019 and the Post Graduate Medical Education Regulations, 2023. If it is found at any time that MBBS degree is not recognized, the candidature / result of the candidate shall be cancelled/ deemed to be cancelled.</p><p>Candidates should go through this bulletin carefully for eligibility criteria before applying. Queries pertaining to eligibility and other issues will only be entertained if the information requested is not given in the bulletin of information or NBEMS website. No Queries of the Guardians/Parents will be entertained on telephone with regard to the eligibility and disclosure of the results.</p><p>Submission of incomplete online application form not in accordance with prescribed instructions shall invite rejection of the application. In such cases, the examination fee shall not be refunded.</p><p>Candidate found ineligible at any stage of NEET-PG 2025 Examination, will not be permitted to appear in the examination. In an unlikely event of any ineligible candidate appearing and/or passing the NEET-PG 2025 examination, the results/candidature of such candidate shall be cancelled and/or is deemed to be cancelled, even if result has been declared or score card has been issued.</p><p>NBEMS reserves the right to withdraw permission, if any, granted inadvertently to any candidate who is not eligible to appear in the NEET-PG 2025 Examinations even though the admit card/roll number has been issued or name/roll number is displayed on NBEMS website.</p><p>Fee shall neither be carried forward to a future exam nor refunded under any circumstances. Application once submitted can not be withdrawn.</p><p>Candidates’ eligibility is purely provisional &amp; is subjected to the fulfilment of eligibility criteria as prescribed in this Information Bulletin.</p><p>Instructions in the Information Bulletin are liable to change based on decisions taken by the NBEMS / MoHFW / NMC / DGHS from time to time.</p><p>There is no equity or any rights that are / or deemed to be arising in favour of candidate. Candidates are required to refer to the latest bulletin or corrigendum that may be issued to incorporate these changes. Refer NBEMS website in for latest updates or corrigendum.</p><p>The existing schedule, pattern, policy and guidelines are for ready reference only but in no way, they are or are ought to be treated as representative or acknowledgment of fact that NBEMS is bound to follow the same in future.</p><p>NBEMS reserves its absolute right to alter, amend, modify or apply any or some of the instructions/ guidelines contained in this information bulletin.</p><p>In case of any ambiguity in interpretation of any of the instructions / terms / rules / criteria regarding the determination of eligibility/conduct of examinations / registration of candidates/information contained herein, the interpretation of the NBEMS shall be final and binding in nature. In case of any discrepancy in the information contained in English and Hindi version of the bulletin, the information mentioned in English language shall be considered final.</p><p>Request shall not be entertained for change in date/center of examination under any circumstances. Candidates are advised not to canvass for such representation.</p><p>Admit Cards for NEET-PG 2025 can be downloaded at NBEMS website from 11th June 2025 onwards. Candidates found ineligible before conduct of the examination shall not be issued admit cards.</p><p>Result of NEET-PG 2025 shall be published on NBEMS websites</p><p>NEET-PG 2025 shall be conducted by NBEMS at various exam centres engaged for the purpose. Candidates are advised to familiarise themselves with the route and location of the exam centre well in advance to avoid any last minute delay in arrival to the exam centre. Please refer Chapter on details of Test Day Procedures.</p><p>The examination test centre staff on duty is authorized to verify the identity of candidates and may take steps to verify and record the identity of candidates. Candidates are required to extend requisite cooperation.</p><p>Possession/Use of mobile phones/Electronic devices is strictly prohibited in the premises of NBEMS test Centres. Candidates shall be liable for penal action for Possession/ Use of Mobile phones/ Electronic devices. Resorting to use of any unfair practice in NEET-PG 2025 shall be dealt with as per the Unfair Mean Guidelines of NBEMS. Such candidates shall be imposed academic and/or criminal punishments as may be applicable. Please go through guidelines detailed in Chapter on use of unfair means in the examination.</p><p>Demo Test: A demo test shall be available for the benefit of candidates to familiarise themselves with the Computer Based Test format at website Candidates will be able to access the Demo test tentatively from 05th June 2025 onwards.</p><p>The candidates should communicate with NBEMS regarding matters related to NEET-PG 2025 as per prescribed Protocols only, detailed under Chapter on Communication Protocols.</p><p>Candidates are encouraged to communicate for NEET-PG 2025 through “Helpdesk” tab which can be accessed after the applicant login to its application account. The correspondence through post should be addressed to the Executive Director, National Board of Examinations in Medical Sciences, Medical Enclave, Mahatma Gandhi Marg, Ansari Nagar, New Delhi110029. Candidates are requested to superscribe the envelope with the subject matter of the correspondence for expeditious processing.</p><p>The Registration for NEET-PG 2025 at the time of Counseling to be conducted by designated counseling authority will be as per the details of candidates submitted in NBEMS NEET-PG 2025. Hence, candidates are advised to maintain their same Registration details e.g. mobile number, Email ID etc. as provided in the NBEMS NEET-PG 2025 application form.</p><p>The jurisdiction for court cases/disputes shall be at New Delhi only.</p></div></div></div></div></div></div><p>&nbsp;&nbsp;</p>

405. Criminal cases cannot be lodged against Doctors because they prescribed costlier drugs: HC

     Tue, 29 Apr 2025 09:41:19 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/02/01/231362-orissa-high-court.webp' /><p style="text-align: justify; "><b>Cuttack:</b>&nbsp;Observing that prescribing any chemo drug or medicine to any patient is the sole prerogative and expertise of the treating doctor, the <a href="https://medicaldialogues.in/topics/odisha-high-court">Orissa High Court </a>recently quashed criminal proceedings against a doctor, who was accused of showing undue favour to various <a href="https://medicaldialogues.in/topics/pharmaceutical-companies">pharmaceutical companies</a> and prescribing costlier medicines to the patients suffering from cancer.</p><p style="text-align: justify; ">The HC bench comprising Justice Aditya Kumar Mohapatra held that a doctor should not be held criminally liable for prescribing any particular drug of any pharma company unless the said drug(s) are hazardous, non-standard or substandard quality/brand, or restricted by the appropriate Authority of the Government.</p><p style="text-align: justify; ">Opining that the treating doctor is ethically, morally and legally obligated to prescribe the best medicine to the cancer patients, the HC bench further observed, </p><blockquote style="text-align: justify; "><i>"...prescribing any chemo drug or medicine to any patient is the sole prerogative and expertise of the treating doctors. In the matter of cancer treatment, the patients have right to choose their line of treatment and drugs, as per standard protocol, on the basis of counseling from the different available alternative line of treatment / drugs and as per their financial capability. It is the ethical, moral and legal obligation of the treating doctor to prescribe the best medicine to the blood cancer patients as there is a thin line between the life and death of the patients suffering from this sort of fatal disease."</i></blockquote><p style="text-align: justify; ">Further observing that there should not be any discrimination in the matter of treatment based on the ground of rich and poor and highlighting that the State is constitutionally obligated to provide the best medicine and treatment to the patients, the HC bench further ruled,</p><blockquote style="text-align: justify; "><i>"For prescribing any particular drug of any pharmaceutical company for treatment of a disease like this, a doctor should not be held criminally liable, unless the said drug(s) is hazardous, non-Standard or substandard quality/brand or restricted by the appropriate Authority of the Government For that reason, if the pharma company is benefitted, the same cannot be treated as an undue favour or loss to the Government exchequer. Especially when the patients, on their own informed consent and volition, have paid for the said drugs from their own pockets. Similarly, the Government cannot compel any patient to consume any particular drugs/medicines just because the said medicine/drugs are procured by the government or because the said drugs are cheaper than the alternatives, which might be more efficacious. Moreover, the price of the said drug in question has been fixed by the appropriate authority of the Government."</i></blockquote><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/top-videos/new-nmc-regulations-bar-doctors-from-receiving-gifts-travel-facilities-from-pharma-companies-115899" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: New NMC regulations bar doctors from receiving gifts, travel facilities from pharma companies</i></b></a></p><p style="text-align: justify; ">The Court noted that the prescription audit conducted by the Government agency has not pointed out any such illegalities during the relevant period and the Screening Committee, which scrutinized the application and bill including the medical prescription did not object to the same at any point of time, the Court held that the doctor <i>"should not be criminally liable for the alleged fraud, forgery, cheating and misappropriation etc. or undue favour etc."</i></p><p style="text-align: justify; ">FIR was lodged against the petitioner, a professor and head of the department of haematology of SCB Medical College &amp; Hospital, Cuttack, on 12.12.2017 by the vigilance department based on a complaint. In the said FIR, it was alleged that the doctor had abused his official position by showing undue favour to various pharmaceutical companies. The allegations also involved violations of one "Odisha State Treatment Fund (OSTF)", which was established by the State in December 2011 for providing respite to the poor patients under the BPL category seeking treatment for fatal ailments such as cancer and chronic heart ailments.</p><p style="text-align: justify; ">Challenging the criminal proceedings initiated against him under section 13(2) read with 13(I)(c)(d) of the P.C. Act, 1988, along with sections 409/420/120B of the IPC, the petitioner doctor approached the High Court.</p><p style="text-align: justify; ">After perusing the case record, the Court noted that after registration of the instant FIR and the petitioner was released from jail custody, the Government constituted an expert team of three doctors, out of whom two are not experts in the field of treating blood cancer patients.</p><blockquote style="text-align: justify; "><i>"Moreover, the principles of natural justice has not been followed in the said Inquiry as the petitioner and other accused persons have neither been afforded an opportunity of hearing nor has any notice been served upon them. Therefore, the said inquiry and its finding are not sustainable in the eyes of law," </i>noted the Court.</blockquote><p style="text-align: justify; ">It also opined that there should have been a preliminary inquiry in the case by an expert committee of doctors of the concerned field, especially where there were allegations involving the prescription of a particular cancer treatment drug and the matter of the treatment of poor patients.&nbsp;</p><blockquote style="text-align: justify; "><i>"More so, it should have been ensured that the committee members do not have any conflict of interest with the accused-doctor(s), and the principles of natural justice should have been followed in the said inquiry. In the instant case, the aforesaid mandatory principles as envisaged have not been followed prior to the initiation of this criminal Prosecution,"</i> the Court noted.</blockquote><p style="text-align: justify; ">It was observed by the Court that the fundamental allegation in this case related to prescribing costlier medicines, i.e. "Atgam" and "Hamsyl" instead of "Thymogam" and "L-Asparaginase" to the blood cancer patients. These patients were treated under the OSTF Scheme, and upon being involved in the prescription of these drugs, it was alleged that the petitioner had violated the guidelines of the OSTF Scheme and ethical code and showed undue favours to the said Pharma companies, causing an equivalent loss to the Government.&nbsp;</p><p style="text-align: justify; ">However, the court observed,&nbsp;</p><blockquote style="text-align: justify; "><i>"It is also the admitted position of the prosecution that none of the rules or provisions of the OSTF Scheme has been violated in this case by the petitioner or co-accused. The OSTF guideline never envisage or restrict or put any embargo to prescribe costlier medicine, especially when the same is better and necessary for the treatment. Similarly, the OSTF Guideline never envisages that cheaper medicine should be prescribed irrespective of the quality and result. None of the patients have also made any complaint against the accused-doctors regarding lack of any treatment or incompletion treatment or pressurization for purchasing the specific drug(s) in question. Similarly, there was no allegation that the drug(s) in question is/are of substandard quality or non-standard quality. Rather, the drug in question are of standard quality and produce better result as per the research study."</i></blockquote><p style="text-align: justify; ">The Court further noted that prescribing any chemo drug or medicine to any patient is the sole prerogative and expertise of the treating doctors, and it is the ethical, moral and legal obligation of the treating doctor to prescribe the best medicine to the blood cancer patients, considering the fatal nature of the disease.</p><p style="text-align: justify; ">Therefore, the Court opined that a doctor should not be held criminally liable for prescribing any particular drug of any pharmaceutical company for treatment of a disease like this <i>"unless the said drug(s) is hazardous, non-Standard or substandard quality/brand or restricted by the appropriate Authority of the Government."</i></p><blockquote style="text-align: justify; "><i>"The prescription audit conducted by the Government agency has not pointed out any such illegalities during the relevant period. The Screening Committee who have scrutinized the application and bill including medical prescription have not objected to the same in any point of time. Hence, petitioner should not be criminally liable for the alleged fraud, forgery, cheating and misappropriation etc. or undue favour etc."</i> it further observed.</blockquote><p style="text-align: justify; ">At this outset, the Court also highlighted that a doctor cannot be made to face criminal Prosecution if he/she has any acquaintance with any pharma company for engaging him/herself in consultancy agreement with the said pharma company as advisor, and/or he/she attended any seminar or conference, conducted by any such pharma company, as a speaker or advisor because the said doctor has prescribed the drugs of that particular pharma company.</p><blockquote style="text-align: justify; "><i>"Otherwise each and every doctor in the country would face criminal prosecution,"</i> noted the Court.</blockquote><p style="text-align: justify; ">Further observing that the petitioner attended the seminars/conferences and training programs as a mandatory requirement for career advancement and promotion of doctors, the Court noted that <i>"the benefit extended to him by the Emcure Pharma Company and/or Pfizer Pharma Company towards hospitalities, transportation and accommodation, cannot be treated as illegal. More so, he had attended the Conference at Minnesota, USA in the year 2013, and the alleged Drug Peg L-Asparaginase i.e. Hamsyl was produced by the Emcure Pharma Company in the year 2015, and the petitioner has also never prescribed any such drug Hamsyl of the said Emcure Pharma Company."</i></p><blockquote style="text-align: justify; "><i>"In conclusion, if this sort of proceeding is encouraged, then no doctor would ever endeavor to treat any patient fairly and fearlessly as per the best treatment standards (including drugs) available. Therefore, he should not be made criminally liable on the ground of showing favour to that Company for any Offences as alleged against him,"</i>&nbsp;it mentioned in the order.</blockquote><blockquote style="text-align: justify; "><i>"Furthermore, a criminal case cannot be lodged against a Doctor, because he/she has prescribed costlier drugs or chemo injection which is beneficial and better resultant than the other available drugs. Moreover, in the instant case, other doctors of that institution/ department had also prescribed the similar drugs/ chemo injection to their patients availing benefits under the OSTF Scheme and they have been excluded from the case,"</i> it further observed.</blockquote><p style="text-align: justify; ">The Court also noted that the doctor was exonerated in the departmental proceedings, and no contravention of OSTF, MCI, or any guidelines could be attributed to the petitioner.</p><p style="text-align: justify; "><i>"In fact, the Petitioner was neither found to have violated the prescription audit nor was it established that the Petitioner had endorsed the prescription of the drugs in question. In fact, the only charge which has been established against the Petitioner is with regard to the non-submission of property returns. Therefore, it appears that the competent authority, in the Departmental Proceeding initiated against the petitioner on self-same allegations, has also opined that there are no such illegalities committed by the petitioner,"</i> the Court observed.</p><p style="text-align: justify; ">Accordingly, the Court held that the very initiation of the criminal proceedings, without conducting a preliminary inquiry by experts was "ex-facie illegal". <i>"Moreover, no prima facie case of the alleged offences is made out from the uncontroverted allegations narrated in the FIR against the petitioner. Furthermore, the arbitrariness, discrimination, malafide and blatant illegalities on the part of the prosecution are apparent on the face of this case. In such view of the matter, this court has no hesitation in arriving at the conclusion that the present case falls squarely within the parameters, with regard to quashing of a proceeding..."</i> it held.</p><p style="text-align: justify; "><b><i>To view the order, click on the link below:</i></b></p><p style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/orissa-hc-order-284882.pdf"><b><i>https://medicaldialogues.in/pdf_upload/orissa-hc-order-284882.pdf</i></b></a></p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/nmc-investigates-30-doctors-for-accepting-pharma-freebies-report-142196" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: NMC investigates 30 doctors for accepting pharma freebies: Report</i></b></a></p>

406. Medical Bulletin 29/ April/ 2025

     Tue, 29 Apr 2025 09:30:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284878-sleep-46.webp' /><p style="text-align: justify; "><b>Here are the top medical news for the day:</b></p><div class="pasted-from-word-wrapper"><div style="text-align: justify;"><b>Ultra-Processed Foods Dominate U.S. Grocery Carts, Raising Health Concerns</b></div><div style="text-align: justify;">Nearly half of all grocery purchases in the U.S. are ultra-processed foods (UPFs), raising alarms among public health experts. A new study published in Public Health Nutrition analyzed over 33 million food items bought by 59,939 American households in 2020, using the NOVA classification system to assess levels of food processing.</div><div style="text-align: justify;">The research found that 48% of packaged food and 38% of beverages were UPFs—foods heavily engineered with additives and ingredients rarely used in home cooking. These included soft drinks, snacks, mixed dishes, and soups. While whole foods like fruits and vegetables had minimal UPFs, they made up only a small share (12%) of overall purchases.</div><div style="text-align: justify;">Purchases of UPFs were highest among non-Hispanic white households (49%), followed by Black (47%), Hispanic (46%), and other ethnic groups (43%). Households with lower income and lower education levels also bought more UPFs, regardless of race. This suggests persistent socioeconomic and racial disparities in diet quality.</div><div style="text-align: justify;">“Carbonated beverages topped the list for UPF content at 90%, followed by soups and mixed dishes (81%), and snacks and sweets (71%).” Meanwhile, dairy beverages and fruit juices showed significant variation between racial groups.</div><div style="text-align: justify;">Importantly, the study only captured in-home purchases, potentially underrepresenting beverage consumption—especially among non-Hispanic Black households, who may buy more sugary drinks outside the home.</div><div style="text-align: justify;">The findings highlight the pervasive role of UPFs in American diets and point to the need for federal policy action. Unlike countries that have begun regulating food processing and marketing, the U.S. lacks nationwide measures to limit UPF consumption.</div><div style="text-align: justify;">Researchers urge stronger policies to reduce UPF intake and promote healthier diets, especially in vulnerable communities disproportionately affected by chronic diseases linked to ultra-processed foods.</div><div style="text-align: justify;">Reference: Exploring disparities in the proportion of ultra-processed foods and beverages purchased in grocery stores by US households in 2020. Dunford, E.K., Miles, D.R., Popkin, B.M. Public Health Nutrition (2025). DOI: 10.1017/S1368980025000606, https://www.cambridge.org/core/journals/public-health-nutrition/article/exploring-disparities-in-the-proportion-of-ultraprocessed-foods-and-beverages-purchased-in-grocery-stores-by-us-households-in-2020/845F4FA3CCBAEC37A3CA9124AE0538AD</div><div></div><div style="text-align: justify;"><b>Study on HOPE Technique Shows Promise for Safe Lung Preservation Before Transplantation</b></div><div style="text-align: justify;">A study titled "Evaluation of Hypothermic Oxygenated Machine Perfusion (HOPE) for Lung Preservation" has demonstrated that the hypothermic oxygenated machine perfusion (HOPE) technique is a safe and effective method for preserving donor lungs, even with total out-of-body times nearing 20 hours. The study, presented by Jitte Jennekens, MSc, organ perfusionist/transplant coordinator at UMC Utrecht in the Netherlands, was unveiled at the International Society of Heart and Lung Transplantation (ISHLT) Annual Meeting in Boston.</div><div style="text-align: justify;">"This technique has been used for preserving livers and kidneys and is undergoing trials for hearts, but it hasn't been widely studied for lung preservation," said Jennekens.</div><div style="text-align: justify;">Ex vivo lung perfusion (EVLP) is an established method that allows donor lungs to be preserved and evaluated outside the body before transplantation. The lungs are connected to a pump and ventilator, perfused with a physiological fluid, and sometimes reconditioned. Typically, donor lungs are transported on ice, then warmed to 37°C for functional testing using normothermic EVLP (nEVLP), before being returned to ice until transplantation.</div><div style="text-align: justify;">The UMC Utrecht’s HOPE protocol improves upon this process by eliminating the second cooling phase. After an hour of nEVLP, lungs are maintained at 12°C until transplantation. In a comparison of 12 cases using the nEVLP-HOPE protocol with 118 historical cases of direct lung transplantation without perfusion, no lungs in the HOPE group were rejected. Short-term outcomes were comparable between the two groups.</div><div style="text-align: justify;">“Our results confirm that HOPE is a safe and effective preservation method following normothermic EVLP,” Jennekens said. The next step, according to Jennekens, is determining which preservation strategy works best for specific types of donor lungs, paving the way for future optimization of donor lungs with targeted therapies.</div><div style="text-align: justify;">References: Park, Chanmin; Ko, Yong Jae; Kim, Hee Youn; Sagas, Michael; Eddosary, Melfy, Social Behavior and Personality: an international journal, 2016</div><div></div><div style="text-align: justify;"><b>Study Warns of Rising Yellow Fever (YFV) Threat Amid Global Trends</b></div><div style="text-align: justify;">A recent study published in npj Viruses warns that global trends such as urbanization, increased international travel, and the expansion of mosquito habitats are heightening the risk of yellow fever (YFV) spreading beyond its current endemic regions. Yellow fever (YF), caused by YFV, is an acute viral illness primarily transmitted by the Aedes aegypti mosquito, which thrives in urban environments. Unlike other mosquito-borne diseases, humans infected with YFV are efficient amplifiers, allowing the virus to spread rapidly in cities.</div><div style="text-align: justify;">Historically, yellow fever spread from Africa to the Americas during the transatlantic slave trade. Though an effective vaccine was developed in the 1930s, and mosquito eradication efforts in the Western Hemisphere curbed the virus for decades, recent outbreaks in Africa have raised concerns. These epidemics are attributed to factors such as human population growth, inadequate vaccine coverage, and poor mosquito control.</div><div style="text-align: justify;">The study highlights the Asia-Pacific region as highly vulnerable, with over two billion people living in areas infested with Aedes aegypti mosquitoes and no natural immunity to YFV. Increased international travel by unvaccinated individuals could lead to the virus reaching non-endemic areas, sparking potential outbreaks.</div><div style="text-align: justify;">While the World Health Organization’s “Eliminate Yellow Fever Epidemics” initiative aims to curb the spread, the study emphasizes the need for enhanced vaccine access, better mosquito control, and improved surveillance. Researchers also call for more investment in alternative vaccine platforms and mosquito control strategies. The authors warn that if yellow fever were to spread in today’s world, its high fatality rate could result in a global health crisis even worse than COVID-19.</div><div style="text-align: justify; ">References: Gubler DJ, Hanley KA, Monath TP, et al. Yellow Jack: a modern threat to Asia-Pacific countries? npj Viruses, 2025, DOI: 10.1038/s44298-024-00079-5, https://www.nature.com/articles/s44298-024-00079-5</div></div>

407. Morepen Labs names Kushal Suri as President - International Growth

     Tue, 29 Apr 2025 09:00:50 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284907-kushal-suri-50.webp' /><p><b>Baddi</b>:&nbsp;<span style="text-align: justify;"><a href="https://medicaldialogues.in/topics/Morepen-labs">Morepen Labs</a> has announced the redesignation of Senior Management Personnel, Kushal Suri, as President - International Growth. He previously held the position of Director – API Sales &amp; Marketing.</span></p><p style="text-align: justify; ">The company disclosed the leadership change in a regulatory filing with the BSE, stating,&nbsp;<span style="background-color: rgb(255, 255, 255);">"We wish to inform you that the designation of Mr. Kushal Suri, Senior Management Personnel, has been changed from "Director – API Sales &amp; Marketing" to "President – International Growth," with effect from April 28, 2025.".</span></p><div class="pasted-from-word-wrapper" style="text-align: justify; ">Kushal Suri holds an M.B.A. degree from Regent’s University, London (UK), with a major in Marketing and a minor in Consultancy, along with various other accolades from Harvard University, Cambridge (USA). In the past, he has worked with international organizations such as Houlihan Lokey, Singapore. Kushal Suri is the nephew of Sushil Suri, Chairman &amp; Managing Director, and Sanjay Suri, Whole-Time Director of the Company.</div><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/morepen-labs-receives-anti-allergy-api-loratadine-approval-for-export-to-china-145856">Morepen Labs receives anti-allergy API Loratadine approval for export to China</a></i></b></p><div class="pasted-from-word-wrapper">Morepen Laboratories Ltd. is an Indian pharmaceutical company with a global footprint across 82 countries. All APIs are manufactured in-house at USFDA-approved facilities.&nbsp;</div><p style="text-align: justify; "><br></p>

408. Retired doctor, daughter duped of Rs 11.93 lakh in cyber fraud

     Tue, 29 Apr 2025 09:00:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/01/09/197113-cyber-fraud-1.webp' /><p><b>Mumbai:</b> In yet another case of <a href="https://medicaldialogues.in/topics/cyber-scam">cyber fraud</a> carried out under the pretence of offering <a href="https://medicaldialogues.in/topics/insurance-companies">medical insurance</a>, a retired doctor and his daughter from Mumbai fell victim to the scam, losing a substantial Rs 11.93 lakh. </p><p>According to the FIR registered with the local police, the victims — a 90-year-old doctor, Dr. C. Kaul, and his 65-year-old daughter, R. Kaul, a retired professor from a university in Sweden — were deceived into transferring the amount under the guise of availing medical insurance coverage. </p><p>On March 19, R. Kaul, a resident of Versova, received a call from an unknown number. The caller identified himself as Kuldeep Shriwastak, claiming to be an official from the ONGC office in Bandra East. He informed her that the medical insurance coverage for her father, Dr. C. Kaul, had not yet been approved.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/hyderabad-doctor-duped-of-rs-11-lakh-in-matrimonial-scam-147270"><b>Also Read: Hyderabad Doctor Duped of Rs 11 Lakh in Matrimonial Scam</b></a></p><div class="pasted-from-word-wrapper"><div><span style="background-color: rgb(249, 249, 249);">When she asked what needed to be done, the scammer instructed her to download a 'customer support' app, assuring that her father would receive Rs 10 lakh worth of medical coverage,</span><a href="https://www.freepressjournal.in/mumbai/mumbai-cyber-fraud-father-daughter-duo-loses-1193-lakh-in-fake-medical-insurance-scam-case-registered" rel="nofollow">&nbsp;</a><a href="https://www.freepressjournal.in/mumbai/mumbai-cyber-fraud-father-daughter-duo-loses-1193-lakh-in-fake-medical-insurance-scam-case-registered" rel="nofollow">Free Press Journal</a>&nbsp;reports.</div></div><p>Trusting the caller, R Kaul followed the instructions. Once the app was installed, the scammer requested an upfront payment of ₹1.93 lakh, claiming it was a refundable processing fee. Two days later, Dr. Kaul discovered a shocking debit of ₹10 lakh from his bank account, transferred to an unknown account without his knowledge or consent. </p><p>This incident adds to the growing list of cyber fraud cases in Mumbai and highlights the urgent need for increased digital awareness, especially among senior citizens.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/65-year-old-nri-doctor-scammed-of-rs-977-lakh-in-cyber-fraud-144314"><b>Also Read: 65-year-old NRI doctor scammed of Rs 9.77 Lakh in cyber fraud</b></a></p><div class="pasted-from-word-wrapper"><div><span style="background-color: rgb(249, 249, 249);">Medical Dialogues had previously reported that a retired doctor based in Mumbai has fallen victim to a cyber fraud, losing nearly Rs. 9.77 lakh from his bank account without sharing any One-Time Password (OTP) or banking details. The fraud came to light after multiple unauthorised transactions were made from his Non-Resident External (NRE) account.</span></div></div>

409. Jalgoan Honour Killing: 24-year-old doctor shot dead by Retired CRPF father

     Tue, 29 Apr 2025 08:30:37 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/08/02/245968-dead-1.webp' /><p style="text-align: justify; "><b>Nashik:</b> In a shocking and tragic case of <a href="https://medicaldialogues.in/topics/honour-killing" target="_blank">honour killing</a> in Maharashtra’s Jalgaon district, a 24-year-old <a href="https://medicaldialogues.in/news/health/doctors" target="_blank">doctor</a>&nbsp;was allegedly shot dead by her father, a retired police sub-inspector (PSI) of the Central Reserve Police Force (CRPF), who also critically injured her husband, reportedly over his disapproval of their love marriage.&nbsp;</p><p style="text-align: justify; ">In response, the accused father has been booked under relevant sections of the Bharatiya Nyaya Sanhita (BNS) following an FIR registered at Chopda police station. He was handed over to the police in an injured condition after being thrashed by a mob for allegedly killing his daughter.</p><p style="text-align: justify; ">According to the police, the accused father disapproved of the man his daughter had chosen to marry a year ago and was reportedly upset with her decision to go against the family’s wishes. After learning of their presence in Chopda, he allegedly travelled to the wedding venue and shot his daughter dead.</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/doctors/maha-honour-killing-3rd-year-bhms-student-strangled-set-ablaze-five-arrested-106258" target="_blank">Maha Honour killing: 3rd year BHMS student strangled, set ablaze; five arrested</a></b></p><p style="text-align: justify; ">The exact reason behind the father's sudden decision to kill his daughter remains unclear, and the police are investigating the case from all possible angles to determine what may have triggered him.&nbsp;</p><p style="text-align: justify; ">The incident occurred around 10:15 pm on Saturday during a relative's wedding function in Chopda tehsil of Maharashtra’s Jalgaon district, approximately 400 kilometres from here. While guests were busy celebrating the haldi ceremony, the father allegedly entered the house with his revolver in front of the gathering and opened fire, killing his daughter and injuring his son-in-law.</p><p style="text-align: justify; ">The deceased, identified as a 24-year-old doctor who completed her MBBS from a private medical college in Pimpri, and her husband is a class 9 passout who works as a helper with a private company in Pune. The two eloped and married a year ago when Trupti was pursuing her final-year MBBS studies. They were residing in Pune.&nbsp;</p><p style="text-align: justify; ">“Avinash and Trupti travelled from Pune to Chopda to attend the ceremony when her father learnt about their presence in Chopda. He then travelled some 50 km from his residence at Shirpur in Dhule district to gatecrash the ceremony and open fire at the victims,” Jalgaon’s Superintendent of Police (SP) Maheshwar Reddy told <a href="https://timesofindia.indiatimes.com/city/nashik/former-crpf-cop-shoots-medical-graduate-daughter-dead-in-maharashtra-for-marrying-against-his-wishes/articleshow/120664391.cms" target="_blank" rel="nofollow">TOI</a>.</p><p style="text-align: justify; ">A police official told PTI, “Retired CRPF sub-inspector *** shot dead his daughter with his revolver and seriously injured her husband.. The couple had married just a year ago and were residing in Pune. They had come here for a wedding of a relative."</p><p style="text-align: justify; ">“He arrived at the wedding venue when he found out that the couple were present. After the shooting, people in the vicinity pinned him down and thrashed him. He has been hospitalised and booked for murder. Further probe into what triggered his act is underway," added the official.&nbsp;</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/international/25-year-old-woman-doctor-shot-dead-by-father-in-pakistans-punjab-province-over-honour-116706" target="_blank">25-year-old woman doctor shot dead by father in Pakistan's Punjab province over 'honour'</a></b></p>

410. Integrated digital health gateway ekincare raises investment from MSD IDEA Studio Asia Pacific

     Tue, 29 Apr 2025 08:00:39 -0000

     To date, ekincare has raised a total funding of USD22M since 2015.

     <img src='https://medicaldialogues.in/h-upload/2022/10/15/188021-investment-new.webp' /><p><span style="text-align: justify; background-color: rgb(255, 255, 255);">ekincare, India's AI-powered integrated digital health gateway, has&nbsp;</span><span style="text-align: justify; background-color: rgb(255, 255, 255);">announced the raising of a strategic, undisclosed investment led by global healthcare leader MSD (</span><span style="text-align: justify; background-color: rgb(255, 255, 255);">tradename of Merck &amp; Co., Inc., Rahway, N.J., USA) through MSD IDEA Studio Asia Pacific, an initiative&nbsp;</span><span style="text-align: justify; background-color: rgb(255, 255, 255);">by the MSD Global Health Innovation Fund (MGHIF).&nbsp;</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">The round also saw participation from ekincare’s&nbsp;</span><span style="background-color: rgb(255, 255, 255);">existing investor, HealthQuad, a venture capital fund focused on healthcare innovation.</span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">As per the release, the company stated, "This investment&nbsp;</span><span style="background-color: rgb(255, 255, 255);">round will empower ekincare to advance its mission of revolutionizing corporate primary and preventive&nbsp;</span><span style="background-color: rgb(255, 255, 255);">healthcare through AI-driven, personalized Outpatient Department (OPD) solutions.&nbsp;</span>With this investment, ekincare aims to expand its cashless OPD network and enhance AI-powered analytics to drive better preventive care, chronic disease management, and employee wellness outcomes."</p><div class="pasted-from-word-wrapper"><div style="text-align: justify; "><span style="background-color: rgb(249, 249, 249);">ekincare was f</span>ounded in 2015 by Kiran Kalakuntla, Co-Founder &amp; CEO, Srikanth Samudrala, Co-Founder &amp; CTO, Noel Coutinho, Co-Founder &amp; CBO. The platform leverages AI, data analytics, and telemedicine that makes preventive healthcare more personalized and accessible. Since its inception, ekincare has partnered with over 1,000 companies and built a network of 40,000+ healthcare providers across India.</div><div style="text-align: justify; "> "Healthcare in India is at a turning point. Lifestyle diseases are on the rise, demand for preventive care is growing, and digital solutions are becoming a necessity. This investment from MSD IDEA Studio, with continued support from HealthQuad, is a visionary step forward for us. Their expertise in medicines, vaccines, and digital health, combined with our AI-driven, customer-centric approach, will help us deliver seamless, personalized healthcare to millions”, said Kiran Kalakuntla, Co-founder &amp;amp; CEO of ekincare.</div><div style="text-align: justify; ">“We see strong potential in our investment in ekincare to accelerate the shift toward personalised and preventive healthcare in India by harnessing the power of technology for both individuals and enterprises,” said Saumick Pal, Head of Digital, Data Analytics &amp; Innovation, MSD Asia Pacific. He added, “India’s vibrant start-up ecosystem is not only growing rapidly but also redefining healthcare through bold innovation and entrepreneurial energy. At MSD, we are committed to expanding access to high-quality Confidential care, and investments in platforms like ekincare reflect our belief that scalable, tech-enabled solutions can make healthcare more proactive, affordable, and inclusive. We look forward to supporting visionary start-ups like ekincare that are reshaping the future of health in India by making it more accessible.”</div><div style="text-align: justify; ">Ajay Mahipal, Partner at HealthQuad, said, “ekincare’s AI-powered platform is at the forefront of digital health innovation. Our investment will support their mission of integrating preventive care into the everyday lives of individuals and enterprises, enhancing affordability and access to quality healthcare.”</div></div>

411. NMC revokes relief Granted to jailed Cardiologist

     Tue, 29 Apr 2025 07:36:36 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284843-suspension-revoked.webp' /><p style="text-align: justify; "><b>Ahmedabad:</b>&nbsp;<span style="background-color: rgb(255, 255, 255);">After the Gujarat Medical Council urged the <a href="https://medicaldialogues.in/topics/NMC">National Medical Commission (NMC)</a> to revoke relief granted to jailed cardiologist Dr. Prashant Vazirani, citing serious threats to public health, the apex medical regulator has vacated its earlier stay on suspending his registration over alleged misconduct in the Khyati Hospital <a href="https://medicaldialogues.in/topics/pmjay">PMJAY</a> scam.</span></p><p style="text-align: justify; ">The Apex Medical Commission vacated its stay on April 10 after the GMC wrote to NMC defending the decision to suspend the cardiologist. The state medical council also requested NMC to "immediately" vacate its stay on the Council's order dated November 28, 2024, through which the State Medical Council had suspended the concerned cardiologist for three years.</p><p style="text-align: justify; ">On Monday, the medical council received the new order issued by the Ethics and Medical Registration Board (EMRB) of NMC vacating the stay order.</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/gujarat-medical-council-vs-nmc-state-council-asks-apex-body-to-revoke-relief-to-jailed-cardiologist-cites-threat-to-public-health-147265" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: Gujarat Medical Council Vs NMC: State Council asks apex body to revoke relief to Jailed Cardiologist, cites threat to public health</i></b></a></p><p style="text-align: justify; ">As per the latest media report by <a href="https://indianexpress.com/article/cities/ahmedabad/after-objection-by-gujarat-medical-council-nmc-vacates-its-stay-order-on-suspension-of-cardiologist-accused-in-pmjay-deaths-case-9971207/" rel="nofollow">Indian Express</a>, the new NMC order dated 25.04.2025 mentioned how the Gujarat medical council in its letter dated April 23 had brought forth certain new facts to the notice of EMRB, including the fact of Dr. Vazirani "being arrested and not being granted bail, conducting angioplasties and angiographies while not being empanelled under the PMJAY scheme and the surgeries being conducted without informed consent of patients, and other instances of unethical conduct on part of the doctor."</p><p style="text-align: justify; ">In the new order, the NMC Secretary, Dr. Raghav Langer, further directed all the parties to submit the relevant case-related documents, investigation report, chargesheet filed in the matter etc. to the <a href="https://medicaldialogues.in/topics/EMRB">EMRB</a> within 10 days from the receipt of the order. This direction has been issued by the Apex Medical Commission to ensure that the appeal made by Dr. Vazirani can be heard and decided on its merits.</p><p style="text-align: justify; ">Dr. Vazirani was accused of conducting "completely unnecessary" angioplasty surgeries on residents of a village in Mehsana, as part of "the wider conspiracy" to cheat the state exchequer under the PMJAY scheme.</p><p style="text-align: justify; ">Medical Dialogues has been reporting about the PMJAY scam that came to light in November 2024, when two patients, who attended a free medical camp organised by&nbsp;<a href="https://medicaldialogues.in/topics/khyati-hospital">Khyati Hospital </a>under the Ayushman Bharat Pradhan Mantri Jan Arogya Yojana (PM-JAY), passed away due to postoperative complications following Angioplasty procedures.</p><div class="pasted-from-word-wrapper"><div id="ATS_mid2"></div><div class="inside-post-ad-2 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_2"></div><div class="pasted-from-word-wrapper"><div class="inside-post-ad-3 inside-post-ad ads_common_inside_post" id="inside_post_content_ad_3"></div><p style="text-align: justify; ">This incident caused widespread outrage as an angioplasty was performed at the hospital on 19 patients, and two of them died, while 5 others were kept on ventilation. These 19 people were brought to Khyati Hospital by ambulance for treatment after they attended the free health checkup camp in Borisna village of Kadi taluka on November 10. Around 80 to 90 people were examined at the camp.</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/pmjay-botched-angioplasty-case-court-denies-bail-to-khyati-hospital-director-144651"><i><b>Also Read: PMJAY Botched Angioplasty Case: Court denies bail to Khyati Hospital Director</b></i></a></p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Following this, three FIRs were registered, two at the behest of the kin of the deceased and one by a doctor from the Government-appointed panel. During the investigations, it was revealed that the hospital performed unnecessary angioplasty procedures on several PMJAY cardholders to siphon off government money. The inquiry committee constituted by the State government in its preliminary probe found that the deceased did not require the heart procedure.</p><p style="text-align: justify; ">Dr Prashant Vazirani was the doctor who reportedly carried out the said surgeries. Following this, he was arrested along with hospital CEO Rahul Jain, marketing director Chirag Rajput, marketing executive Milind Patel, and his two assistants, Pankil Patel and Pratik Bhatt, and directors Rajshree Kothari and Sanjay Patolia.</p><p style="text-align: justify; ">Following his arrest, the medical council decided to debar his registration for three years in November 2024. Challenging this decision, Dr Vazirani filed an appeal to the NMC in December 2024, which is still pending.</p></div><p style="text-align: justify; ">Meanwhile, in an order dated April 10, 2025, NMC stayed the <a href="https://medicaldialogues.in/topics/gujarat-medical-council">Gujarat Medical Council</a>&nbsp;order debarring the registration of Dr. Vazirani. The NMC referred to a previous 2022 judgment by the Nagpur Bench of the Bombay High Court in a similar case, saying that immediate action could cause “irreparable harm” to the doctor before his appeal is fully heard.</p><p style="text-align: justify; ">However, the council on April 24 wrote to NMC requesting the latter to vacate the stay adding that if the stay continued, "it would pose a significant threat to public health and undermine trust in the medical regulatory framework.</p><p style="text-align: justify; ">The State Council had highlighted that unwarranted angiography and angioplasty surgeries were performed on unsuspecting villagers in order to illicitly claim benefits under the PMJAY scheme and how Dr. Vazirani was arrested and has not been granted bail yet.</p><p style="text-align: justify; ">Terming NMC's decision to grant a stay on the council order shocking, the Gujarat Medical Council mentioned that the top medical regulatory body decided to grant the stay without hearing the Gujarat Government through the department concerned as well as without calling for case-related documents from the State council.</p></div><p style="text-align: justify; ">Now NMC has vacated its stay order and in the latest order dated April 25, it mentioned, "...after going through the contents of the communication dated April 23, 2025, of GMC, and material facts provided therein, EMRB, after careful consideration, hereby vacates the ex-parte stay order dated April 10, 2025."</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/nmc-stays-debarment-of-cardiologist-jailed-in-khyati-hospital-scam-147251" style="background-color: rgb(255, 255, 255);"><b><i>Also Read: NMC stays debarment of cardiologist jailed in Khyati Hospital Scam</i></b></a></p>

412. Medanta to set up 400-bed Hospital in Guwahati, invest Rs 500 crore

     Tue, 29 Apr 2025 07:35:10 -0000

     <img src='https://medicaldialogues.in/h-upload/2020/06/11/130223-medanta.webp' /><p><b>Gurugram:</b>&nbsp;Reaffirming its commitment to deliver world-class healthcare where it is needed most, Global Health Limited “<a href="https://medicaldialogues.in/topics/medanta-hospital">Medanta</a>”, one of the largest private multi-specialty tertiary care providers operating in the North and East regions of India, announced its entry into the North East with its plan to establish a super-speciality hospital in Guwahati. The Board of Directors, in its meeting held recently, approved the purchase of 3 acres of land from <a href="https://medicaldialogues.in/state-news/assam">Assam</a> Electricity Grid Corporation Ltd. for Rs. 30 crore plus incidental expenses for registration and possession of the land.&nbsp;</p><p>The Board has also approved plans to invest approximately Rs. 500 crores, including the cost of land, in developing a state-of-the-art, 400-bed super specialty hospital. The proposed site is strategically located on National Highway 27, offering seamless connectivity across the entire Northeast region. This expansion aims to strengthen healthcare infrastructure and will serve over 50 million people across Assam and its neighbouring states. Medanta’s foray into the region will be transformative, bringing world-class medical expertise, cutting-edge technology, and comprehensive care across more than 20 super specialties, including transplants and advanced robotic procedures.</p><p><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/medanta-to-expand-footprints-in-new-delhi-signs-om-agreement-for-750-bed-super-speciality-hospital-137674" style="background-color: rgb(255, 255, 255);"><b>Also Read: Medanta to expand footprints in New Delhi, signs O&amp;M agreement for 750-bed super speciality hospital</b></a></p><p>Dr. Naresh Trehan, Chairman and Managing Director of Medanta, shared,</p><p>"At the Advantage Assam 2.0 Summit, I emphasized the need to bring world-class healthcare to the North East, a region that has long been underserved. Today, with the Board’s approval to acquire land in Guwahati and our plans to build a 400-bed super specialty hospital, we are taking a decisive step toward fulfilling that vision. This marks the beginning of a transformative journey to strengthen healthcare infrastructure and deliver advanced medical care closer to millions across Assam and its neighbouring states. At Medanta, we believe that quality healthcare should be a right, not a privilege, and through this initiative, we reaffirm our mission to make cutting-edge healthcare accessible to all, no matter where they live."</p><p>Highlighting the strategic importance of the expansion, Mr. Pankaj Sahni, Group CEO, Medanta, said,</p><p>“The North East region is rich in cultural diversity, but continues to face a significant gap in access to high-quality healthcare. Guwahati, often regarded as the gateway to the North East, offers strong connectivity across the entire region and is ideally positioned to address this critical need. We are pleased to announce the setting up of a 400-bed super specialty hospital in Guwahati, which will allow us to bridge the healthcare gap and bring world-class, high-end medical care within easy reach of over 50 million people. We are excited to contribute to strengthening the healthcare ecosystem and to serve communities that have long been underserved.”</p><p><b style="background-color: rgb(255, 255, 255);"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/aiims-leads-the-way-3-indian-hospitals-in-worlds-best-list-146830" style="background-color: rgb(255, 255, 255);">Also Read: AIIMS Leads the Way- 3 Indian Hospitals in World's Best list</a></b></p>

413. Bond service allotment for Super speciality doctors: DMER Maharashtra Revises schedule, Vacancy

     Tue, 29 Apr 2025 07:24:22 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284865-revised-schedule.webp' /><p style="text-align: justify; "><b>Maharashtra-</b> The Director of Medical Education &amp; Research (DMER), Maharashtra has revised the schedule and vacancy position for the Central round allotment of bond services to Super Speciality candidates by filling the online application form and allotment.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">As per the notice issued by the DMER Maharashtra in this regard, the online application and online allotment that started from 23rd April 2025 will now end today i.e. 29th April 2025. Earlier, it was scheduled to end on 27th April 2025.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/dmer-maharashtra-releases-provisional-recommendation-list-for-bond-service-allotment-of-pg-medicos-147429"><b>Also Read:&nbsp;</b>DMER Maharashtra Releases Provisional Recommendation List for Bond Service allotment of PG medicos</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u>SCHEDULE</u></b></p><div dir="ltr"><table style="text-align: justify; "><colgroup><col width="50"><col width="174"><col width="201"><col width="199"></colgroup><tbody><tr><td><p dir="ltr" style="text-align: center; "><b>S.NO</b></p></td><td><p dir="ltr" style="text-align: center; "><b>DATE</b></p></td><td><p dir="ltr" style="text-align: center; "><b>TIME</b></p></td><td><p dir="ltr" style="text-align: center; "><b>SPECIALITY</b></p></td></tr><tr><td><p dir="ltr">1</p></td><td><p dir="ltr">23 to 29th April 2025</p></td><td><p dir="ltr">11.00 am, 11.59 pm</p></td><td><p dir="ltr">Filling of the online application form and online Choice filling process.</p></td></tr><tr><td><p dir="ltr">2</p></td><td><p dir="ltr">30 April 2025</p></td><td><p dir="ltr">after 5.00 pm.</p></td><td><p dir="ltr">Declaration of allotment of bond service to the candidate and issue of a recommendation letter from the web portal through the Login ID.</p></td></tr></tbody></table></div><p dir="ltr" style="text-align: justify; ">Meanwhile, the candidate must submit an attested photocopy of the requisite documents at the respective institute where they will be allotted the post as per the list given below-</p><p dir="ltr" style="text-align: justify; ">a SSC Passing Certificate / valid passport (as proof of age).</p><p dir="ltr" style="text-align: justify; ">b Superspeciality mark-sheets</p><p dir="ltr" style="text-align: justify; ">c Degree Mark sheet / Grade Certificate</p><p dir="ltr" style="text-align: justify; ">d Attempt certificate of all MBBS, MD/MS examinations from the head of the institution.</p><p dir="ltr" style="text-align: justify; ">e MBBS degree / Passing certificate.</p><p dir="ltr" style="text-align: justify; ">f MD/M.S. Degree Passing Certificate.</p><p dir="ltr" style="text-align: justify; ">g Permanent Registration certificate of the Maharashtra Medical Council or other State Medical Councils in India/MCI.</p><p dir="ltr" style="text-align: justify; ">h Online recommendation letter for allotment of bond service. (will be mailed to the candidates on their registered email ID).</p><p dir="ltr" style="text-align: justify; "><b><u>RULE OF TIE-BREAKER</u></b></p><p dir="ltr" style="text-align: justify; ">Selection of a candidate for the vacant post shall be as per the procedure for the preparation of the merit list as given below.</p><p dir="ltr" style="text-align: justify; ">First Level- The Candidate having the Highest Mark in DM/MCH postgraduate examination (Superspeciality) will be preferred,</p><p dir="ltr" style="text-align: justify; ">If the tie persists, then</p><p dir="ltr" style="text-align: justify; ">Second Level- The Candidate having the Highest aggregate mark in the final <a href="https://medicaldialogues.in/topics/md-ms">MD / MS</a> will be preferred.</p><p dir="ltr" style="text-align: justify; ">If the tie persists, then</p><p dir="ltr" style="text-align: justify; ">Third Level- The Candidate having the Highest Mark in the Final MBBS will be preferred.</p><p dir="ltr" style="text-align: justify; ">If the tie persists, then</p><p dir="ltr" style="text-align: justify; ">Fourth Level- The older candidate will be preferred.</p><p dir="ltr" style="text-align: justify; ">Along with this, DMER Maharashtra has also released the Revised Vacancy for online allotment of Government Social responsibility service (Bond Service) to Super-Speciality Degree holders. As per the revised vacancy, a total of 339 seats are vacant across all hospitals of Maharashtra.</p><p dir="ltr" style="text-align: justify; "><b><u><i>To view the revised vacancy, click the link below</i></u></b></p></div><div class="hocal-draggable" draggable="true"><a href="https://medicaldialogues.in/pdf_upload/revised-vacancy-for-ss-bond-service-winter-2024-dated-28042025-284873.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/revised-vacancy-for-ss-bond-service-winter-2024-dated-28042025-284873.pdf</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; "><b><u><i>To view the notice, click the link below</i></u></b></p></div><div class="pasted-from-word-wrapper"><p><a href="https://medicaldialogues.in/pdf_upload/dmer-maharashtra-284868.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/dmer-maharashtra-284868.pdf</a></p></div><div class="pasted-from-word-wrapper"><div></div></div>

414. 26 senior doctors transferred, major overhaul at Delhi Hospitals

     Tue, 29 Apr 2025 07:15:20 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/10/03/255193-transferred.webp' /><p style="text-align: justify; "><b>New Delhi: </b>In a significant administrative move aimed at strengthening public healthcare facilities, the Delhi government has appointed and <a href="https://medicaldialogues.in/topics/doctors-transferred" target="_blank">transferred </a>26 senior medical officials, including medical superintendents, principals and medical directors from their current postings to major government hospitals across the capital.</p><p style="text-align: justify; ">The major healthcare institutions include Lok Nayak Hospital, Guru Teg Bahadur (GTB) Hospital, Deen Dayal Upadhyay Hospital, Dr. Baba Saheb Ambedkar Hospital, and GB Pant Hospital.</p><p style="text-align: justify; ">An official order issued by the Lieutenant Governor (L-G) mentioned that Dr Rati Makkar has been appointed as the new Director General of Health Services (DGHS) in Delhi. She was earlier working as a Senior Medical Officer at Deen Dayal Upadhyay Hospital. He replaced the outgoing head amid a broader strategy to strengthen the capital’s healthcare administration.</p><p style="text-align: justify; "><b>Also read- <a href="https://medicaldialogues.in/news/health/doctors/2-doctors-transferred-barred-from-private-practice-144419" target="_blank">2 doctors transferred, barred from private practice</a></b></p><p style="text-align: justify; ">Dr BL Chaudhary is now the new Medical Director of Lok Nayak Hospital, replacing Dr Suresh Kumar. Dr Kumar has been transferred to Ambedkar Medical College, where he will serve as Principal and Director.</p><p style="text-align: justify; ">Professor Vinod Kumar, who was earlier with the Orthopaedics Department at Lok Nayak Hospital, has been appointed as the new Medical Superintendent of Guru Teg Bahadur (GTB) Hospital. Professor Abid Gilani will now head GB Pant Hospital as its Medical Director.</p><p style="text-align: justify; ">As per <a href="https://www.newindianexpress.com/cities/delhi/2025/Apr/29/delhi-government-transfers-heads-of-26-major-hospitals-in-major-healthcare-reshuffle" target="_blank" rel="nofollow">TNIE </a>news report, the senior doctors have been transferred with immediate effect and directed to join their new postings without waiting for official relieving orders from their current departments which indicated newly appointed officials to take charge at their assigned positions right away, while those who have been transferred are expected to promptly hand over their duties and assume their new responsibilities without delay.</p><p style="text-align: justify; ">According to officials from the Health Department, the decision reflects an effort to streamline hospital administration and boost service delivery across the public health system.</p><p style="text-align: justify; ">Medical Dialogues recently reported that the Andhra Pradesh Health Department has appointed new principals and superintendents at several government medical colleges and hospitals across the state. Altogether, six government medical colleges got new principals, while five government teaching hospitals received new superintendents. Among these, three new principals were appointed to fill vacant posts, and three existing principals and one superintendent were transferred.</p><p style="text-align: justify; "><b>Also read-<a href="https://medicaldialogues.in/news/health/doctors/ap-appoints-6-new-principals-5-superintendents-to-govt-medical-college-hospitals-147410" target="_blank"> AP appoints 6 new Principals, 5 Superintendents at Govt Medical College Hospitals</a></b></p>

415. MP Medical Council FMG Clinical Clerkship, Internship Counselling merit list released

     Tue, 29 Apr 2025 07:11:14 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284855-merit-list.webp' /><p style="text-align: justify; "><b>Madhya Pradesh-</b> Madhya Pradesh Director of Medical Education (MPDME) has released the merit list of candidates registered for Madhya Pradesh Medical Council-Foreign Medical Graduates (MPMC-FMG) Clinical Clerkship/Internship for December 2024.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">The list has been released in a PDF format on the official website of MPDME, The list includes important details such as Common Rank, MP state rank, FMGE roll number, candidate name, gender, MP domicile, score obtained (Out of 300), result Status and session.</p><p dir="ltr" style="text-align: justify; ">In the list, a total of 1595 candidates' names were mentioned in the merit list of candidates registered for the MPMC-FMG Clinical Clerkship/Internship for December 2024. </p><p dir="ltr" style="text-align: justify; ">Click on the link below to view the merit list:</p><p dir="ltr" style="text-align: justify; "><a href="https://medicaldialogues.in/pdf_upload/mpdme-284858.pdf" target="_blank">https://medicaldialogues.in/pdf_upload/mpdme-284858.pdf</a></p></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">As per the guidelines, every candidate has to select all Colleges/ Institutes according to their choice in the choice-filling section. If any candidate has selected a few or limited colleges/ institutes and does not get a seat allotment in those colleges/ institutes by his/ her merit, then under any circumstances, he/ she will not be allotted an internship in this session. Therefore, every candidate is hereby specially informed to select all colleges/ institutes according to his/ her choice.</p><p dir="ltr" style="text-align: justify; "><b><u>ALLOTMENT PROCESS</u></b></p><p dir="ltr" style="text-align: justify; ">1 The seats will be allotted to candidates whose names appear in the merit list published by the Madhya Pradesh Medical Council.</p><p dir="ltr" style="text-align: justify; ">2 As per the NMC's circular, the allotment starts on "Group A permitted college" and then "Group B recognised college".</p><p dir="ltr" style="text-align: justify; ">3 Allotment of seats shall be made on the basis of merit cum choice filled by the candidate and availability of seats.</p><p dir="ltr" style="text-align: justify; ">Meanwhile, FMGE-qualified candidates from previous sessions, i.e. June 2023, December 2023, June 2024, and earlier, who have not secured admission in the June 2024 or any prior counselling sessions are eligible to participate in the December 2024 counselling session. However, admitted candidates from previous sessions will not be allowed to participate in the current session.&nbsp;</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/1336-seats-up-for-grabs-in-mp-medical-council-fmg-clinical-clerkship-internship-counseling-check-out-schedule-guidelines-seat-matrix-147299"><b>Also Read:&nbsp;</b>1336 seats up for grabs in MP Medical Council FMG Clinical Clerkship, Internship Counseling, check out schedule, guidelines, seat matrix</a></div><div class="pasted-from-word-wrapper"><div></div></div>

416. Bayer appoints Guru Ramamurthy as new CFO for Crop Science division

     Tue, 29 Apr 2025 06:55:04 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284862-guru-ramamurthy-50.webp' /><p style="text-align: justify; "><strong>Monheim:</strong>&nbsp;<a href="https://medicaldialogues.in/topics/Bayer">Bayer </a>has announced that Guru Ramamurthy will become the new Chief Financial Officer (CFO) for Bayer's Crop Science division. He will succeed Oliver Rittgen who has decided to pursue a career opportunity outside of Bayer after 25 years with the company.</p><p style="text-align: justify; "> In his current role, Guru Ramamurthy is serving as CFO of Bayer US. The change will become effective as of July 1, 2025. With over 20 years of experience at Bayer, Ramamurthy brings extensive financial expertise and a proven track record in driving transformation and business growth.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Since joining Bayer in 2001, Ramamurthy has held various finance leadership roles across multiple business segments and geographies. Prior to being appointed as the CFO of Bayer US, he served as CFO of <a href="https://medicaldialogues.in/topics/AskBio">AskBio</a>, Bayer’s wholly owned and independently operated gene therapy company. Previously, he was the Global CFO of Bayer’s Medical Care division and has held country and regional CFO positions across diverse segments. Over the course of his career, he has held key finance roles in Germany, Italy, Japan, and the United States.</p><p style="text-align: justify; ">“Guru has a strong track record of enabling business turnarounds and driving transformation through a holistic business perspective. His ability to shape business strategies to boost profitability and growth to deliver results, while building high-performing finance teams, has made his leadership stand out. His collaborative and innovative approaches have further amplified his impact. I am looking forward to working with him to shape the future success of our business,” said Rodrigo Santos, Member of the Board of Bayer AG and President of the company's Crop Science Division.</p><p style="text-align: justify; ">Guru Ramamurthy will be based in St. Louis, MO. The successor for his current role will be announced at a later date.</p><p style="text-align: justify; ">Oliver Rittgen joined Bayer in 2000 and served in various leadership roles across Finance. Before assuming the position as CFO for the Crop Science division in 2024, he held the CFO role for Bayer’s Consumer Health division. Prior to that, he held several regional CFO and Corporate Finance positions in Germany, Finland, and Thailand.</p><p style="text-align: justify; ">“Oliver has successfully been driving business performance and transformation across the divisions and has always made it a priority to develop his organization and people at the same time. His innovative and entrepreneurial thinking has helped us to further develop the financial operations of our business. I want to thank him for his valuable contributions and wish him all the best for the future,” added Rodrigo Santos.</p></div>

417. GMC Jammu Medical Superintendent removed over circular on Pahalgam attack

     Tue, 29 Apr 2025 06:34:31 -0000

     <img src='https://medicaldialogues.in/h-upload/2022/07/04/179940-transfer-1.webp' /><p style="text-align: justify; ">Jammu: A day after issuing a circular directing hospital staff to stay vigilant amid rising tensions along the borders in <a href="https://medicaldialogues.in/state-news/jammu-kashmir" target="_blank" style="background-color: rgb(249, 249, 249);">Jammu and Kashmir,</a> the medical superintendent of Jammu’s Government Medical College Hospital (GMCH) was repatriated on Saturday to the Directorate of Health Services, Jammu. The controversial circular, which spaked significant debate, was later withdrawn by the principal of the college, Dr. Ashutosh Gupta.</p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><a class="also-read-media-wrap" href="https://medicaldialogues.in/news/education/medical-colleges/2nd-year-gmc-jammu-mbbs-student-allegedly-commits-suicide-147408"><img class="also-read-media" data-src="https://medicaldialogues.in/h-upload/2025/02/12/273942-suicide-2.webp"></a><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-colleges/2nd-year-gmc-jammu-mbbs-student-allegedly-commits-suicide-147408"><b><u><span class="read-this-also">Also Read:</span>2nd year GMC Jammu MBBS Student allegedly commits suicide</u></b></a><div></div></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Dr. Varinder Trisal, the medical superintendent of Ramban district hospital, will be in charge of the Government Medical College &amp; Hospital instead of Dr. Narinder Bhutyal. Civil Secretariat, Government of Jammu and Kashmir, Health &amp; Medical Education Department issued an order stating, “Dr. Narinder Bhutyal, I/C Medical Superintendent, Government Medical College, Jammu, is repatriated forthwith and attached in the Directorate of Health Services, Jammu for further duties.” Furthermore, Dr. Varinder Trisal, I/C Medical Superintendent, District Hospital Ramban, is deputed to Government Medical College, Jammu on standard terms and conditions of deputation. He shall also look after the charge of Medical Superintendent, Government Medical College, Hospital Jammu. Meanwhile, Dr. Sudershan Singh Katoch, currently a medical officer at the J&amp;K Medical Supplies Corporation Limited, will temporarily take charge of the Ramban district hospital.</p> <p style="text-align: justify; ">This came days after Dr. Narinder Bhutyal issued an order titled “Readiness Measures in view of Cross-Border Tension in UT of J&amp;K.” Medical Dialogues had earlier reported that the<a href="https://medicaldialogues.in/topics/gmc-jammu" target="_blank"> Government Medical College Hospital (GMCH) Jammu</a> officially withdrew a circular it issued on April 25, 2025, which had instructed hospital staff to remain on high alert due to reported cross-border tensions in the Union Territory of Jammu &amp; Kashmir after the Pahalgam attack.</p></div><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><a class="also-read-media-wrap" href="https://medicaldialogues.in/news/health/hospital-diagnostics/gmc-jammu-withdraws-staff-alert-directive-amid-cross-border-tensions-147321"><img class="also-read-media" data-src="https://medicaldialogues.in/h-upload/2023/05/16/209777-gmc-jammu.webp"></a><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/hospital-diagnostics/gmc-jammu-withdraws-staff-alert-directive-amid-cross-border-tensions-147321"><b><u><span class="read-this-also">Also Read:</span>GMC Jammu withdraws Staff Alert Directive amid Cross-border tensions</u></b></a><div></div></div></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The circular reads, “In view of the prevailing cross-border tension in the UT of J&amp;K, all Staff members are hereby directed to remain alert and ensure complete preparedness to meet any exigencies that may arise at any time. The Store Officer and Store Keepers, GMCH, are requested to keep all essential supplies, emergency medicines, and critical equipment in a state of readiness for immediate use to meet any exigency.”</p> <p style="text-align: justify; ">Other than that, all hospital staff were advised to restrict unnecessary holidays and directed to ensure their presence within the hospital premises during duty hours to maintain uninterrupted and effective patient care. A 24x7 Control Room was established to coordinate all emergency responses. The control room would function round the clock and may be contacted for any urgent requirements or issues. Shockingly, the transfer order was withdrawn just after one day.</p></div>

418. Roche secures USFDA Breakthrough Device Designation for AI-driven companion diagnostic for non small cell lung cancer

     Tue, 29 Apr 2025 06:15:55 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/01/12/197702-roche.webp' /><p><b style="text-align: justify;">Basel:&nbsp;</b><a href="https://medicaldialogues.in/topics/Roche" style="text-align: justify;">Roche </a><span style="text-align: justify;">has announced that&nbsp;</span>the VENTANA TROP2 (EPR20043) RxDx Device for non-small cell lung cancer has received Breakthrough Device Designation from&nbsp;<span style="text-align: justify;">the U.S. Food and Drug Administration (FDA).</span></p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">“This FDA Breakthrough Device Designation is another example of our commitment to deliver innovation that enables more precise diagnosis in oncology,” said Matt Sause, CEO of Roche Diagnostics. “This solution, which leverages our industry-leading expertise in companion diagnostics development, uses artificial intelligence for a greater depth of sample analysis, helping to deliver truly personalised treatment.”</p><p style="text-align: justify; ">The VENTANA TROP2 (EPR20043) RxDx Device is a computational pathology device, consisting of the TROP2 algorithm, navify Digital Pathology Image Management System, Roche Digital Pathology scanners (DP 200, DP 600) and the VENTANA TROP2 (EPR20043) RxDx Assay used with OptiView DAB Detection Kit for staining on a BenchMark ULTRA IHC/ISH staining instrument. The VENTANA TROP2 (EPR20043) RxDx Device analyses whole slide images of <a href="https://medicaldialogues.in/topics/non-small-cell-lung-cancer">non-small cell lung cancer </a>(NSCLC) tissue stained with TROP2 to compute a quantitative TROP2 score.</p><p style="text-align: justify; ">The algorithm incorporates AstraZeneca’s computational pathology platform, Quantitative Continuous Scoring (QCS), which enables a level of diagnostic precision not possible with traditional manual scoring methods.</p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/roche-to-infuse-usd-50-billion-in-pharma-diagnostics-in-us-over-next-five-years-147123">Roche to infuse USD 50 billion in pharma, diagnostics in US over next five years</a></i></b></p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">“This FDA Breakthrough Device Designation underscores the potential of our computational pathology platform to enable more personalised treatment decisions for people with cancer,” said Susan Galbraith, Executive Vice President, Oncology Haematology R&amp;D, AstraZeneca.</p><p style="text-align: justify; ">The FDA granting Breakthrough Device Designation has the potential to make a TROP2 CDx AI-driven system available sooner, which could aid in identifying patients with NSCLC most likely to benefit from treatment with Daiichi Sankyo and AstraZeneca’s DATROWAY (datopotamab deruxtecan-dlnk). DATROWAY is a specifically engineered TROP2-directed DXd antibody drug conjugate (ADC) discovered by Daiichi Sankyo and being jointly developed by AstraZeneca and Daiichi Sankyo.</p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/roche-columvi-gets-european-commission-nod-as-bispecific-antibody-for-diffuse-large-b-cell-lymphoma-after-initial-therapy-146611">Roche Columvi gets European Commission nod as bispecific antibody for diffuse large B-cell lymphoma after initial therapy</a></i></b></p></div>

419. UP: 26-year-old nurse allegedly commits suicide with overdose of anaesthesia

     Tue, 29 Apr 2025 06:13:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/08/02/245968-dead-1.webp' /><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Shahjahanpur: In an unfortunate incident, a 26-year-old nurse allegedly committed <a href="https://medicaldialogues.in/topics/doctor-commits-suicide" target="_blank">suicide</a> by giving herself an overdose of anaesthesia at her house on the campus of a private medical college in Uttar Pradesh's Shahjahanpur, police said on Monday.</p><p style="text-align: justify; ">According to a UNI report, Superintendent of Police Rajesh Dwivedi said Aarti Deval completed her nursing course from Varun Arjun Medical College, a private institute in Tilhar area of the district. She was employed at the medical college and stayed in a house on its campus.&nbsp;</p><p style="text-align: justify;">When she did not report for duty on Monday, her colleagues went to her residence and saw that the room door was locked from inside, police said.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/nursing/news/25-year-old-nurse-stabbed-to-death-in-patna-115896"><b>Also Read:25-year-old nurse stabbed to death in Patna</b></a></p><p style="text-align: justify;">Police reached the spot and broke open the door to find Deval’s body.</p><p>According to a&nbsp;<a href="https://www.amarujala.com/uttar-pradesh/shahjahanpur/the-dead-body-of-a-staff-nurse-was-found-in-the-hostel-of-a-private-medical-college-shahjahanpur-news-c-122-1-spn1004-142668-2025-04-29" rel="nofollow">Amar Ujala</a> news report, the victim's father, Mahesh Deval, said that his daughter Aarti Deval worked as a staff nurse in Varun Arjun Medical College. She lived in room number 44 on the first floor of the girls' hostel. He used to talk to his daughter daily. He called his daughter Aarti at 7 am on Monday, but she did not pick up the phone.</p><p style="text-align: justify;">According to the initial investigation, she took an excessive dose of anaesthesia, which led to her death, an officer said, reports UNI.</p><p style="text-align: justify;">The body has been sent for post-mortem examination, and the reason behind Deval taking the extreme step is being ascertained, he added.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/nursing/news/25-year-old-bhopal-nurse-kills-self-with-overdose-of-anesthesia-102645"><b>Also Read:25-year-old Bhopal nurse kills self with overdose of anesthesia</b></a></p></div>

420. NEET SS 2024 Results: Respiratory Medicine Leads with Highest Cut-Off, Orthopaedics Lowest

     Tue, 29 Apr 2025 06:00:13 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/28/284762-neet-ss-2024-rsult.webp' /><p style="text-align: justify; "><b>New Delhi- </b>The National Board of Examinations in Medical Sciences (<a href="https://medicaldialogues.in/topics//nbe" target="_blank">NBEMS</a>) officially announced the National Eligibility and Entrance Test-Super Speciality (NEET SS) exam 2024&nbsp; results recently, along with the group-specific qualifying cut-off scores. The exam was conducted on March 29 and 30, 2025, for admission to various DM, MCh and DrNB Super Speciality courses across India.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">As per the official notice released by NBEMS in this regard, candidates who have scored 50th percentile or above in their respective subject groups have been declared qualified in NEET-SS 2024. The result is available on the official website of NBE, however, individual scorecards can be downloaded from May 2, 2025.</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/check-out-neet-ss-2024-results-scorecards-available-from-may-2-147318"><b>Also Read:&nbsp;</b>Check out NEET SS 2024 results, Scorecards Available from May 2</a></div><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">The cut-off scores, calculated at the 50th percentile for each group, show significant variations across different speciality streams. The highest qualifying scores were recorded in the Respiratory Medicine group, which topped the list with the highest overall cut-off at 365. The ENT group ranked second with 350 out of 600, while the Obstetrics and Gynaecology (OBGYN) group ranked third with 354.</p><p dir="ltr" style="text-align: justify; ">Meanwhile, the orthopaedics group recorded the lowest cut-off score of 254. These scores reflect the relative performance of candidates from each group and help standardise the eligibility criteria for admission to super-speciality programmes.</p><p dir="ltr" style="text-align: justify; "><b><i><u>Below is the list of group-specific qualifying scores at the 50th percentile (out of 600)-</u></i></b></p><div dir="ltr"><table style="text-align: justify; "><colgroup><col width="34"><col width="225"><col width="365"></colgroup><tbody><tr><td><p dir="ltr" style="text-align: center; "><b>S.NO</b></p></td><td><p dir="ltr" style="text-align: center; "><b>QUESTION PAPER GROUP</b></p></td><td><p dir="ltr" style="text-align: center; "><b>QUALIFYING CUT-OFF SCORES AT 50TH PERCENTILE (OUT OF 600)</b></p></td></tr><tr><td><p dir="ltr">1</p></td><td><p dir="ltr">ANAESTHESIOLOGY GROUP</p></td><td><p dir="ltr">279</p></td></tr><tr><td><p dir="ltr">2</p></td><td><p dir="ltr">CRITICAL CARE MEDICINE GROUP</p></td><td><p dir="ltr">285</p></td></tr><tr><td><p dir="ltr">3</p></td><td><p dir="ltr">ENT GROUP</p></td><td><p dir="ltr">350</p></td></tr><tr><td><p dir="ltr">4</p></td><td><p dir="ltr">MEDICAL GROUP</p></td><td><p dir="ltr">299</p></td></tr><tr><td><p dir="ltr">5</p></td><td><p dir="ltr">MEDICAL ONCOLOGY GROUP</p></td><td><p dir="ltr">280</p></td></tr><tr><td><p dir="ltr">6</p></td><td><p dir="ltr">MICROBIOLOGY GROUP</p></td><td><p dir="ltr">340</p></td></tr><tr><td><p dir="ltr">7</p></td><td><p dir="ltr">OBSTETRICS AND GYNAECOLOGY GROUP</p></td><td><p dir="ltr">354</p></td></tr><tr><td><p dir="ltr">8</p></td><td><p dir="ltr">ORTHOPAEDICS GROUP</p></td><td><p dir="ltr">254</p></td></tr><tr><td><p dir="ltr">9</p></td><td><p dir="ltr">PAEDIATRIC GROUP</p></td><td><p dir="ltr">287</p></td></tr><tr><td><p dir="ltr">10</p></td><td><p dir="ltr">PATHOLOGY GROUP</p></td><td><p dir="ltr">261</p></td></tr><tr><td><p dir="ltr">11</p></td><td><p dir="ltr">PHARMACOLOGY GROUP</p></td><td><p dir="ltr">315</p></td></tr><tr><td><p dir="ltr">12</p></td><td><p dir="ltr">PSYCHIATRY GROUP</p></td><td><p dir="ltr">311</p></td></tr><tr><td><p dir="ltr">13</p></td><td><p dir="ltr">RADIODIAGNOSIS GROUP</p></td><td><p dir="ltr">315</p></td></tr><tr><td><p dir="ltr">14</p></td><td><p dir="ltr">RESPIRATORY MEDICINE GROUP</p></td><td><p dir="ltr">365</p></td></tr><tr><td><p dir="ltr">15</p></td><td><p dir="ltr">SURGICAL GROUP</p></td><td><p dir="ltr">285</p></td></tr></tbody></table></div><p dir="ltr" style="text-align: justify; ">Moreover, NBEMS, through its notice, notified that each and every question in all question papers of NEET-SS 2024 was reviewed by faculty members from the concerned speciality area after the conduct of NEET-SS 2024 to re-check for technical correctness of the questions as well as answer keys. If any questions were found to be technically incorrect, all candidates were awarded full marks for those specific questions, regardless of whether they attempted them or not.&nbsp;</p></div><div class="pasted-from-word-wrapper"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/education/medical-admissions/neet-ss-2024-result-out-check-group-specific-qualifying-cut-off-scores-147312"><b>Also Read:&nbsp;</b>NEET SS 2024 Result OUT: Check Group Specific Qualifying Cut-Off Scores</a></div><div class="pasted-from-word-wrapper"><div></div></div>

421. Fact Check: Can Drinking Raisin Water Purify Blood in 30-45 Days?

     Tue, 29 Apr 2025 05:30:01 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/18/283596-knee-pain-1.webp' /><p style="text-align: justify; ">An Instagram post claims that Drinking <a href="https://medicaldialogues.in/search?search=raisin#gsc.tab=0&amp;gsc.q=raisin&amp;gsc.page=1" rel="nofollow">Raisin</a> Water Can Purify <a href="https://medicaldialogues.in/search?search=blood#gsc.tab=0&amp;gsc.q=blood&amp;gsc.page=1" rel="nofollow">Blood</a>&nbsp;in 30-45 Days. The claim is FALSE.</p><h3 style="text-align: justify; "><b>Claim</b></h3><p style="text-align: justify; ">In an Instagram post, it is claimed that Drinking Raisin Water Can Purify Blood in 30-45 Days. The post by user <a href="https://www.instagram.com/knowledgebyfact/" rel="nofollow">knowledgebyfact</a> says, "Drinking raisin water daily with empty stomach for 30–45 days. It helps to remove acne / pimples providing glowing skin. It works as a blood purifier."</p><p style="text-align: justify; ">The post can be accessed&nbsp;<a href="https://www.instagram.com/p/DH8IqqkSCu2/" rel="nofollow">here</a>.</p><h3 style="text-align: justify; "><b>Fact Check</b></h3><p style="text-align: justify; ">The claim is FALSE. There is no scientific evidence or medical consensus to back the claim by the user that Drinking Raisin Water Can Purify Blood in 30-45 Days.</p><h3 style="text-align: justify; "><b>How is blood purified?</b></h3><p style="text-align: justify; ">The kidneys are essential for <a href="https://www.niddk.nih.gov/health-information/kidney-disease/kidneys-how-they-work" rel="nofollow">blood purification</a>, filtering about half a cup of blood every minute to remove waste and excess water, which are excreted as urine.</p><p style="text-align: justify; ">When kidney function fails, blood purification is carried out through specialized therapies outside the body. These treatments, used when standard methods like medication or surgery are insufficient, eliminate toxins and harmful substances from the bloodstream via techniques such as dialysis, filtration, or adsorption. These methods act rapidly and are primarily used in three medical scenarios: emergency situations (e.g., plasmapheresis to remove toxins), life-sustaining treatments (e.g., hemodialysis for kidney failure), and managing immune or metabolic conditions (e.g., immunoadsorption for autoimmune disorders).</p><h3 style="text-align: justify; "><b>What are the Health Benefits of Raisins?</b></h3><p style="text-align: justify; "><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7019280/#:~:text=Despite%20a%2060%25%20sugar%20content,be%20favorable%20for%20human%20health." rel="nofollow">Raisins</a> are a nutritious snack with a low-to-moderate glycemic index, making them a healthy option for maintaining blood sugar levels. They are linked to better diet quality and may help reduce appetite. The phenolic compounds in raisins give them antioxidant properties, which can support cardiovascular health. Additionally, raisins promote good oral health due to their antibacterial effects, low adherence to teeth, and ability to maintain an optimal oral pH. While raisins appear to have benefits for colon function, further research is needed to fully understand their impact.</p><h3 style="text-align: justify; "><b>Can Drinking Raisin Water Purify Blood?</b></h3><p style="text-align: justify; ">While raisins offer nutritional benefits, there is no scientific evidence that raisin water can purify, detoxify or cleanse the blood that too in in 30-45 Days. Hence, the claim by user is FALSE</p><p style="text-align: justify; ">Raisins, packed with natural sugars, fiber, and antioxidants, have been increasingly recognized for their potential role in promoting overall well-being. A review published&nbsp;in the <b><i><a href="https://www.researchgate.net/publication/319062831_A_Comprehensive_review_of_Raisins_and_Raisin_components_and_their_relationship_to_human_health" rel="nofollow">Journal of Nutrition and Health</a></i></b> reported that consuming raisins, when compared to other carbohydrate-rich snacks with equal caloric value, can lead to reductions in LDL (bad) cholesterol and blood pressure, and is associated with a lower risk of cardiovascular disease.</p><p style="text-align: justify; ">Similarly, Raisins offer a wide range of health benefits. A study by <a href="https://e-jnh.org/DOIx.php?id=10.4163/jnh.2017.50.3.203" rel="nofollow">Margaret J. Schuster et. al.</a> found that consuming raisins offers several health benefits, contributing to overall wellness and helping prevent various chronic conditions such as cardiovascular disease, type 2 diabetes mellitus, gastrointestinal disorders, and dental caries.</p><p style="text-align: justify; ">Raisins offer some health benefits and may aid in preventing certain chronic conditions, but no scientific evidence or medical consensus supports the user’s claim that raisin water can purify the blood.</p><div contenteditable="false" data-width="252" style="width:252px;" class="image-and-caption-wrapper clearfix hocalwire-draggable float-left"><img src="https://medicaldialogues.in/h-upload/2025/04/26/284519-profile.webp" draggable="true" class="hocalwire-draggable float-left" data-float-none="true" data-uid="2369013SyYAv1nG061WIT3kghjChu89FM9rQ99322691" data-watermark="false" style="text-align: justify; width: 100%; float: left;" info-selector="#info_item_1745649322984"><div class="inside_editor_caption image_caption hocalwire-draggable float-left" id="info_item_1745649322984"></div></div><p style="text-align: justify; ">In a conversation with <b>Dr Poojitha Byreddy, Senior Haematologist, CARE Hospitals, Hi-tech City, Hyderabad</b>, she said, "Some people believe that drinking raisin water can clean or ‘purify’ the blood in 30 to 45 days, but there is no medical proof for this. Our body already has a natural way of removing waste and toxins through the liver and kidneys. While raisins do have healthy nutrients like iron and antioxidants, raisin water alone cannot clean your blood.</p><p style="text-align: justify; ">It’s important to remember that no single food or drink can change how your blood works. Eating a balanced diet and staying healthy is more effective. Always talk to a doctor if you have any concerns about your blood."</p><div contenteditable="false" data-width="252" style="width:252px;" class="image-and-caption-wrapper clearfix hocalwire-draggable float-left"><img src="https://medicaldialogues.in/h-upload/2025/04/26/284521-profile-1.webp" draggable="true" class="hocalwire-draggable float-left" data-float-none="true" data-uid="236904AfQP6TMVvDEKe0iuqi9QV85mlllEnWo9373461" data-watermark="false" style="text-align: justify; width: 100%; float: left;" info-selector="#info_item_1745649373544"><div class="inside_editor_caption image_caption hocalwire-draggable float-left" id="info_item_1745649373544"></div></div><p style="text-align: justify; "><b>Dr Imran Khan, Senior Consultant – Internal Medicine, CARE Hospitals, Musheerabad, Hyderabad </b>said, "Raisin water might help with digestion and give your body some energy, but it won’t ‘purify’ your blood. The idea that a drink can clean your blood is a common myth and not backed by science. Your liver and kidneys already do that job naturally every day. Good health doesn’t come from just one drink. It comes from eating a variety of healthy foods, drinking enough water, and staying active. If you are worried about your health or have specific problems, it’s best to speak with a doctor rather than relying on home remedies."</p><h3 style="text-align: justify; "><b>Medical Dialogues Final Take</b></h3><p style="text-align: justify; ">The claim that drinking raisin water can "purify the blood" is false. Raisin water may offer hydration and health benefits. However, the claim that it can purify blood in 30-45 Days is not supported by any scientific evidence or medical consensus.</p><p style="text-align: justify; ">Hence, the claim is FALSE.</p>

422. Jharkhand HC stays Government's order to remove RIMS Director

     Tue, 29 Apr 2025 05:00:39 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/28/284779-dr-raj-kumar.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Ranchi:&nbsp;</span><span style="text-align: justify;">The </span><a href="https://medicaldialogues.in/topics/jharkhand-high-court" target="_blank" style="text-align: justify;">Jharkhand High Court</a><span style="text-align: justify;"> on Monday stayed the state government's order removing Dr Raj Kumar as the Director of the Rajendra Institute of Medical Sciences (</span><a href="https://medicaldialogues.in/topics/rims" target="_blank" style="text-align: justify;">RIMS</a><span style="text-align: justify;">), Ranchi, with immediate effect.&nbsp;</span></p><p style="text-align: justify; ">The court observed that the manner in which Dr Raj Kumar was removed was legally untenable, stating that a stigmatic order could not be issued without following due process, news agency PTI reported.</p><p style="text-align: justify;">On April 17, Jharkhand Health Minister and RIMS Governing Council Chairman Irfan Ansari issued an order relieving Dr Raj Kumar from his post.</p><p style="text-align: justify;">The government order cited alleged non-compliance with directives issued by the Council of Ministers, the Governing Council, and the Health Department, and described his service as Director as unsatisfactory.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/state-news/jharkhand/former-rims-director-moves-hc-over-dismissal-147224"><b>Also Read:Former RIMS Director Moves HC over Dismissal</b></a></p><p style="text-align: justify;">Referring to the RIMS manual, the government order stated that Dr Raj Kumar was being removed with immediate effect, with three months' salary and allowances. It also mentioned that the decision had the approval of Chief Minister Hemant Soren.</p><p style="text-align: justify;">Dr Raj Kumar challenged the removal in the High Court. In a strongly worded reaction, he termed the move “autocratic” and said he was taken by surprise.</p><p style="text-align: justify;">Hearing the petition on Monday, Justice Deepak Roshan stayed the government's order and issued notices to the state government and other parties, seeking replies through affidavits, reports PTI.</p><p style="text-align: justify;">The court remarked that proper procedure must be followed for such removal, emphasising that no individual can be dismissed in a stigmatising manner without being heard.</p><p style="text-align: justify;">The next hearing is scheduled for May 6.</p><p style="text-align: justify;">The sudden removal of Dr Raj Kumar from the post of RIMS Director had sparked a major political controversy in Jharkhand.</p><p style="text-align: justify;">Leader of Opposition in the Jharkhand Assembly, Babulal Marandi, alleged that Dr Raj Kumar was ousted for refusing to clear payments of several crores of rupees to private diagnostic centres under pressure from the Health Minister and officials.</p><p style="text-align: justify;">Dr Raj Kumar was appointed RIMS Director on January 31, 2024. Prior to that, he served as a professor in the Department of Neurology at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.</p><p style="text-align: justify;">Medical Dialogues had earlier reported that Former Director of the Rajendra Institute of Medical Sciences (RIMS), Ranchi, Dr. Rajkumar, has approached the Jharkhand High Court seeking justice after his abrupt removal from the post. In his petition, he has strongly contested the allegations that led to his removal, calling them entirely baseless and unjust.</p><p style="text-align: justify;"><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/doctors/rims-director-removed-after-governing-body-order-146836"><b>Also Read:RIMS Director removed after Governing Body order</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

423. Fire at Aurobindo Pharma arm Penicillin G facility, no injuries reported

     Tue, 29 Apr 2025 04:45:41 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/08/26/249535-fire-50-1.webp' /><p><b style="text-align: justify;">Hyderabad:</b><span style="text-align: justify;">&nbsp;A </span><a href="https://medicaldialogues.in/topics/fire" style="text-align: justify;">fire </a><span style="text-align: justify;">broke out at Penicillin G manufacturing facility of Lyfius Pharma Private Limited, a subsidiary of Aurobindo Pharma, located in Kakinada SEZ, Thondangi (M), Kakinada District - 533449, Andhra Pradesh, India.</span></p><p><span style="text-align: justify;">Aurobindo disclosed in a BSE filing that the incident occurred around 10:00 PM (IST) on April 27, 2025, in the vicinity of the coal crusher area.</span></p><p style="text-align: justify; ">The fire incident took place due to the self-ignition of coal. The company is in the process of ascertaining the exact reasons for the same.</p><div class="pasted-from-word-wrapper" style="text-align: justify; "> While the&nbsp;<span style="background-color: rgb(249, 249, 249);">incident resulted in damage to certain ancillary equipment,&nbsp;</span><span style="background-color: rgb(249, 249, 249);">with no impact to the core manufacturing infrastructure.</span></div><div class="pasted-from-word-wrapper" style="text-align: justify; ">Importantly, there were no injuries reported.</div><div class="pasted-from-word-wrapper" style="text-align: justify; "><p><span style="background-color: rgb(255, 255, 255);">"The incident is not expected to have material impact on the operations or financials of the group. A thorough assessment of the damage is currently underway," Aurobindo stated.</span></p></div><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">As a precautionary measure and to facilitate necessary equipment replacements, operations at the plant will be temporarily paused for an estimated period of 20 to 25 days. Aurobindo also reassured stakeholders that the facility is fully insured.</p></div><div class="pasted-from-word-wrapper" style="text-align: justify; ">"We remain committed to resuming full operations at the earliest while maintaining the highest safety and quality standards," the company added.</div><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/aurobindo-pharma-arm-curateq-biologics-gets-positive-opinion-for-breast-cancer-drug-dazublys-from-ema-147308">Aurobindo Pharma arm CuraTeQ Biologics gets positive opinion for breast cancer drug Dazublys from EMA</a></i></b></p><p style="text-align: justify; ">Aurobindo Pharma Limited is an integrated global pharmaceutical company headquartered in Hyderabad, India. The Company develops, manufactures, and commercializes a wide range of generic pharmaceuticals, branded specialty pharmaceuticals and active pharmaceutical ingredients globally in over 150 countries. The company has 30 manufacturing and packaging facilities that are approved by regulatory agencies including USFDA, UK MHRA, EDQM, Japan PMDA, WHO, Health Canada, South Africa MCC, Brazil ANVISA. The Company’s product portfolio is spread over seven major therapeutic/product areas encompassing CNS, Anti-Retroviral, CVS, Antibiotics, Gastroenterological, Anti-Diabetics and AntiAllergic, supported by a strong R&amp;D set-up. </p><p style="text-align: justify; "><b><i>Read also: <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/industry/pharma/aurobindo-pharma-gets-usfda-final-tentative-nod-for-different-strengths-of-deep-vein-thrombosis-drug-rivaroxaban-146573">Aurobindo Pharma gets USFDA final, tentative nod for different strengths of deep vein thrombosis drug Rivaroxaban</a></i></b></p>

424. India's health system is largest in the world, says JP Nadda

     Tue, 29 Apr 2025 04:00:19 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284853-jp-nadda.webp' /><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">Chhatrapati Sambhajinagar:&nbsp;</span><span style="background-color: rgb(255, 255, 255);">Union Health Minister </span><a href="https://medicaldialogues.in/topics/jp-Nadda" target="_blank">JP Nadda</a>&nbsp;highlighted that India's healthcare system is the largest in the world, capable of taking care of a large population. He also praised the government’s efforts to produce more doctors to strengthen the healthcare system.</p></div><div class="pasted-from-word-wrapper"><p><span style="text-align: justify;">India has a robust health system capable of taking care of a large population, and the country is also catering to international needs, Union Health Minister </span><a href="https://medicaldialogues.in/topics/jp-Nadda" target="_blank" style="background-color: rgb(249, 249, 249); text-align: justify;">JP Nadda</a><span style="text-align: justify;"> said on Sunday.&nbsp;</span><br></p><p style="text-align: justify;">He was speaking after inaugurating the ‘Kaushalyam’ lab, which is a part of the medical college started by the Hedgewar hospital in Chhatrapati Sambhajinagar in central Maharashtra.</p><p style="text-align: justify;">“We have a robust health system. We should never think it’s weak. People often talk about developments in foreign countries. I ask them about the population there, which is just 10-20 million. A district here could have that many people,” he said, news agency PTI reported.</p><p style="text-align: justify;">India is known for its unity in diversity, and such comparisons don’t hold much weight, said the Union minister.</p><p style="text-align: justify; "><a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/mdtv/healthshorts/jp-nadda-launches-ab-pm-jay-gopabandhu-health-schemes-in-odisha-146521"><b>Also Read:JP Nadda launches AB PM-JAY, Gopabandhu Health Schemes in Odisha</b></a></p><p style="text-align: justify;">“If comparisons are to be made, then it has to be over the administration of 220 crore COVID vaccine doses, including boosters. If India can conduct vaccination on such a massive scale while maintaining the cold chain supply, it tells us that our health system is robust,” he said.</p><p style="text-align: justify;">Nadda said 200 million children are born every year in India and are given various vaccines, which are recorded as well.</p><p style="text-align: justify;">He also highlighted the government’s efforts to produce more doctors. “We are the ones who give doctors to the world. The number of medical seats (MBBS) has increased from 50,000 to 1.18 lakh, while PG seats have gone up from 3,000 to over 65,000,” he said, without specifying the period.</p><p style="text-align: justify;">“We cannot be compared with the London health system. If we call back half of the doctors (produced by India) in London, their health system will collapse,” he said.</p><p style="text-align: justify;">It’s a matter of pride that doctors put their lives on the line to save people, he said.</p><p style="text-align: justify;">“Our detection of tuberculosis and the decline in cases are twice as high as the global average. Our health system is advancing with great strength. People from African countries are coming here for cheaper and better treatment. We are catering to national as well as international needs,” he said.</p><p style="text-align: justify;">Nadda said one can earn lakhs through the medical profession, but the field is aimed at earning the goodwill of millions of people.</p><p style="text-align: justify;">“So you have to decide your course of action… No one gets everything in one life. The priorities should be set and one must strike a balance between self and society,” he said at the high-tech laboratory, reports PTI.</p><p style="text-align: justify;">Nadda also wondered if “international standards should be our standards”.</p><p style="text-align: justify;">“India needs to prepare its own base. So we have to be aware of what we need in the medical field and the way we are moving ahead,” he added.</p><p style="text-align: justify;">Earlier in the day, Nadda said fighting cancer was a top priority area for policymakers, and Rs 3000 crore had been allocated in the last eight years for high-end treatment. He was speaking after inaugurating the Truebeam facility (linear accelerator used in radiation oncology) at the State Cancer Institute here.</p><p style="text-align: justify;"> <a class="editor-inserted-link" target="_blank" href="https://medicaldialogues.in/news/health/fatty-liver-is-preventable-reversible-through-healthy-lifestyle-and-food-habits-jp-nadda-147070"><b>Also Read:Fatty liver is preventable, reversible through healthy lifestyle and food habits: JP Nadda</b></a></p><div class="hocal-draggable" draggable="true"><div class="read-this-also-wrap"><div></div></div></div></div>

425. Single dose of baloxavir lowers the risk of influenza virus transmission to close contacts: NEJM

     Tue, 29 Apr 2025 03:45:45 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/06/02/239922-influenza-521205131-scaled.webp' /><p style="text-align: justify; ">A new study published in <i>The New England Journal of Medicine</i> showed that a single dosage of the antiviral baloxavir marboxil (Xofluza) reduced the rate of influenza virus transmission to household contacts.</p><p style="text-align: justify; ">Because baloxavir marboxil (baloxavir) quickly decreases influenza virus shedding, it may also lessen transmission. Neuramaminidase inhibitor therapy studies have not provided enough proof that they stop transmission to contacts. The use of baloxavir in practical public health strategies is limited by the lack of data regarding its efficacy, effectiveness, appropriate dose administration, or duration of use for the treatment or post-exposure prophylaxis of novel influenza A viruses of pandemic potential, including the highly pathogenic avian influenza A (H5N1) virus. In order to fill the gap in the literature, Arnold Monto and team carried out this investigation.</p><p style="text-align: justify; ">Within 48 hours of the initial symptoms, individuals aged 5 to 64 with an influenza-positive index were randomized 1:1 to receive either baloxavir or a placebo. By day five, the main outcome was the spread of influenza virus from an index patient to a household contact. By day five, the first secondary end goal was the spread of the influenza virus, which caused symptoms.</p><p style="text-align: justify; ">As a whole, 1,457 index patients and 2,681 household contacts were included during the 2019–2024 influenza seasons. Nearly, 726 index patients were randomized to the baloxavir group, and 731 to the placebo group. With an adjusted relative risk reduction of 29%, baloxavir significantly reduced the transmission of laboratory-confirmed influenza by day 5 when compared to placebo.</p><p style="text-align: justify; ">Although the difference was not statistically significant, the adjusted incidence of influenza virus transmission by day 5 that caused symptoms was 5.8% with baloxavir and 7.6% with placebo. During the follow-up period, 7.2% of the index patients in the baloxavir group developed drug-resistant viruses; no resistant viruses were found in household contacts. There were no new warning signs found.</p><p style="text-align: justify; ">Overall, compared to placebo, treatment with a single oral dosage of baloxavir resulted in a decreased rate of influenza virus transmission to close contacts. Across age categories, seasons, influenza types (A[H1N1pdm09], A[H3N2], and B), durations between symptom start and baloxavir or placebo administration, and geographical locations, there was a difference in the transmission incidence favoring baloxavir.&nbsp;</p><p style="text-align: justify; ">Source:</p><p style="text-align: justify; ">Monto, A. S., Kuhlbusch, K., Bernasconi, C., Cao, B., Cohen, H. A., Graham, E., Hurt, A. C., Katugampola, L., Kamezawa, T., Lauring, A. S., McLean, B., Takazono, T., Widmer, A., Wildum, S., &amp; Cowling, B. J. (2025). Efficacy of baloxavir treatment in preventing transmission of influenza. The New England Journal of Medicine, 392(16), 1582–1593. <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2413156" rel="nofollow">https://doi.org/10.1056/nejmoa2413156</a></p>

426. Tryptase has limited sensitivity as Anaphylaxis Biomarker, claims study

     Tue, 29 Apr 2025 03:30:29 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/10/09/256062-anaphylaxis.webp' /><p style="text-align: justify; ">Tryptase is the most commonly used biomarker for diagnosing anaphylaxis; however, it has limited sensitivity. A recent systematic review found its sensitivity to be only 49%, raising concerns about potential misclassification of anaphylaxis cases despite its status as the most reliable current marker.</p><div class="pasted-from-word-wrapper"><p dir="ltr" style="text-align: justify; ">Anaphylaxis is a life-threatening allergic reaction commonly triggered by food, venom, or drugs. Clinical criteria are central to diagnosing anaphylaxis. However, laboratory biomarkers could provide valuable confirmation when clinical diagnosis is challenging. </p><p dir="ltr" style="text-align: justify; ">They aimed to evaluate key biomarkers including tryptase, histamine, platelet-activating factor (PAF), PAF-acetylhydrolase (PAF-AH), and urinary prostaglandin D2 (PGD2) for their diagnostic utility in anaphylaxis. A systematic review was conducted following PRISMA-DTA guidelines. Studies published between 2004 and 2024 from Embase and MedLine were included if they evaluated the diagnostic test accuracy of tryptase, histamine, PAF, PAF-AH, or urinary PGD2 in confirmed anaphylaxis cases. Pooled sensitivity and specificity estimates were calculated using the diagmeta package in R. </p><p dir="ltr" style="text-align: justify; ">Results: Twenty-eight studies with 18,749 patients were included, of which 3,329 had anaphylaxis. Tryptase was the most frequently studied biomarker (24 studies), with a pooled sensitivity and specificity of 0.49 and 0.82, respectively. Histamine had a pooled sensitivity of 0.76 and specificity of 0.69. Limited data were available for PAF, PAF-AH, and urinary PGD2. Studies suggest that tryptase remains the most widely used and accessible biomarker for diagnosing anaphylaxis mainly using the "Rule of Twos" diagnosis strategy. Histamine and urinary PGD2 show potential, though their application is limited by practical challenges. </p><p dir="ltr" style="text-align: justify; ">Further research is needed to establish the diagnostic roles of PAF and PAF-AH, particularly in non-IgE mediated anaphylaxis pathways.</p><div style="text-align: justify;"></div><p dir="ltr" style="text-align: justify; ">Reference:</p><p dir="ltr" style="text-align: justify; ">Khalaf R, Prosty C, Davalan W, Abrams E, Kaouache M, Ben-Shoshan M. Diagnostic Utility of Biomarkers in Anaphylaxis: A Systematic Review and Meta-Analysis. J Allergy Clin Immunol Pract. 2025 Apr 14:S2213-2198(25)00362-9. doi: 10.1016/j.jaip.2025.04.008. Epub ahead of print. PMID: 40239922.</p><div style="text-align: justify;"></div></div>

427. Hypercortisolism Affects 1 in 4 Patients with Difficult-to-Control Type 2 Diabetes: Study Finds

     Tue, 29 Apr 2025 03:15:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/12/13/264770-hypercortisolism.webp' /><p style="text-align: justify; ">USA: A recent study published in <em>Diabetes Care</em> has highlighted the significant role of hypercortisolism in patients with difficult-to-control type 2 diabetes. Researchers found that approximately one-quarter of individuals with inadequately managed type 2 diabetes, despite being on multiple medications, exhibited hypercortisolism, a condition characterized by excessive cortisol levels in the body.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">Despite the use of various glucose-lowering medications, many individuals with type 2 diabetes still fail to achieve their glycemic targets. Cortisol, known as the "stress hormone," plays a key role in regulating metabolism, blood pressure, and the body’s response to stress. However, chronic elevation of cortisol levels can have detrimental effects, particularly in individuals with type 2 diabetes, where it can worsen hyperglycemia. </p><p style="text-align: justify; ">In the prospective, observational study, John B. Buse, University of North Carolina School of Medicine, Chapel Hill, NC, and colleagues evaluated the prevalence of hypercortisolism as a potential factor contributing to poor glucose control. </p><p style="text-align: justify; ">For this purpose, the researchers screened individuals with type 2 diabetes and HbA1c levels ranging from 7.5% to 11.5% (58–102 mmol/mol) who were on two or more glucose-lowering medications, with or without micro-/macrovascular complications, or those taking multiple blood pressure–lowering medications. A 1-mg dexamethasone suppression test (DST) was conducted, excluding common causes of false-positive results.</p><p style="text-align: justify; ">The primary endpoint was the prevalence of hypercortisolism, defined as post-DST cortisol levels exceeding 1.8 μg/dL (50 nmol/L). The researchers also used multiple logistic regression to assess the characteristics associated with hypercortisolism and evaluated the percentage of participants with hypercortisolism and adrenal imaging abnormalities. </p><p style="text-align: justify; ">Key Findings:</p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Post-DST cortisol was unsuppressed in 252 of 1,057 participants, with a prevalence of 23.8%.</span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">The prevalence of hypercortisolism was 33.3% among participants with cardiac disorders.</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Among those taking three or more blood pressure–lowering medications, the prevalence of hypercortisolism was 36.6%.</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">34.7% of participants with hypercortisolism had adrenal imaging abnormalities.</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Factors associated with a higher prevalence of hypercortisolism included:</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Use of sodium–glucose cotransporter 2 inhibitors (odds ratio 1.558).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p>&nbsp;<span style="text-align: justify;">•&nbsp;</span><span style="text-align: justify; background-color: rgb(255, 255, 255);">Use of maximum-dose glucagon-like peptide 1 receptor agonists (odds ratio 1.544).</span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Use of tirzepatide (odds ratio 1.981).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">A higher number of blood pressure–lowering medications (odds ratio 1.390).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Older age (odds ratio 1.316).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">BMI &lt;30 kg/m2 (odds ratio 1.639).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Non-Latino/Hispanic ethnicity (odds ratio 3.718).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; ">•&nbsp;<span style="background-color: rgb(255, 255, 255);">Use of fibrates (odds ratio 2.676) or analgesics (odds ratio 1.457).</span><span style="background-color: rgb(255, 255, 255);"></span></p><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);"></span><span>•&nbsp;</span><span style="background-color: rgb(255, 255, 255);">All associations were statistically significant.</span></p><p style="text-align: justify; ">The authors revealed that hypercortisolism was identified in approximately 23.8% of individuals with difficult-to-control type 2 diabetes, despite the use of multiple medications. They discovered that this condition was associated with several factors, including older age, lower body mass index (BMI), non-Latino/Hispanic ethnicity, a higher burden of hypertension medications, and the use of fibrates, analgesics, or newer glucose-lowering treatments. These findings emphasize the role of hypercortisolism in exacerbating hyperglycemia in individuals with inadequately controlled type 2 diabetes.</p><p style="text-align: justify; ">The authors also suggest that screening for hypercortisolism could be beneficial for patients who are not meeting glycemic targets despite treatment with multiple medications, providing valuable insights into the challenges of managing type 2 diabetes.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">John B. Buse, Steven E. Kahn, Vanita R. Aroda, Richard J. Auchus, Timothy Bailey, Irina Bancos, Robert S. Busch, Elena A. Christofides, Ralph A. DeFronzo, Bradley Eilerman, James W. Findling, Vivian Fonseca, Oksana Hamidi, Yehuda Handelsman, Harold J. Miller, Jonathan G. Ownby, John C. Parker, Athena Philis-Tsimikas, Richard Pratley, Julio Rosenstock, Michael H. Shanik, Lance L. Sloan, Guillermo Umpierrez, Iulia Cristina Tudor, Tina K. Schlafly, Daniel Einhorn, CATALYST Investigators; Prevalence of Hypercortisolism in Difficult-to-Control Type 2 Diabetes. Diabetes Care 2025; dc242841. https://doi.org/10.2337/dc24-2841</p></div>

428. Study Warns of Rising Yellow Fever (YFV) Threat Amid Global Trends

     Tue, 29 Apr 2025 03:00:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284871-mdtv-2025-04-29t124918094.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">A recent study published in<i> npj Viruses </i>warns that global trends such as urbanization, increased international travel, and the expansion of mosquito habitats are heightening the risk of <a href="https://medicaldialogues.in/topics/yellow-fever">yellow fever</a> (YFV) spreading beyond its current endemic regions. Yellow fever (YF), caused by YFV, is an acute viral illness primarily transmitted by the <a href="https://medicaldialogues.in/topics/Aedes">Aedes </a>aegypti mosquito, which thrives in urban environments. Unlike other <a href="https://medicaldialogues.in/topics/mosquito-borne-diseases">mosquito-borne diseases</a>, humans infected with YFV are efficient amplifiers, allowing the virus to spread rapidly in cities.</div><div style="text-align: justify;">Historically, yellow fever spread from Africa to the Americas during the transatlantic slave trade. Though an effective <a href="https://medicaldialogues.in/topics/vaccine">vaccine </a>was developed in the 1930s, and mosquito eradication efforts in the Western Hemisphere curbed the virus for decades, recent outbreaks in Africa have raised concerns. These epidemics are attributed to factors such as human population growth, inadequate vaccine coverage, and poor mosquito control.</div><div style="text-align: justify;">The study highlights the Asia-Pacific region as highly vulnerable, with over two billion people living in areas infested with Aedes aegypti mosquitoes and no natural immunity to YFV. Increased international travel by unvaccinated individuals could lead to the virus reaching non-endemic areas, sparking potential outbreaks.</div><div style="text-align: justify;">While the World Health Organization’s “Eliminate Yellow Fever Epidemics” initiative aims to curb the spread, the study emphasizes the need for enhanced vaccine access, better mosquito control, and improved surveillance. Researchers also call for more investment in alternative vaccine platforms and mosquito control strategies. The authors warn that if yellow fever were to spread in today’s world, its high fatality rate could result in a global health crisis even worse than COVID-19.</div><div style="text-align: justify;">References: Gubler DJ, Hanley KA, Monath TP, et al. Yellow Jack: a modern threat to Asia-Pacific countries? npj Viruses, 2025, DOI: 10.1038/s44298-024-00079-5, https://www.nature.com/articles/s44298-024-00079-5 </div><div></div></div>

429. Study on HOPE Technique Promising for Safe Lung Preservation Before Transplantation

     Tue, 29 Apr 2025 02:45:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284869-mdtv-2025-04-29t124416209.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">A study titled "Evaluation of Hypothermic Oxygenated Machine Perfusion (HOPE) for <a href="https://medicaldialogues.in/topics/lung">Lung </a>Preservation" has demonstrated that the hypothermic oxygenated machine perfusion (HOPE) technique is a safe and effective method for preserving donor lungs, even with total out-of-body times nearing 20 hours. The study, presented by Jitte Jennekens, MSc, organ perfusionist/transplant coordinator at UMC Utrecht in the Netherlands, was unveiled at the International Society of Heart and Lung Transplantation (ISHLT) Annual Meeting in Boston.</div><div style="text-align: justify;">"This technique has been used for preserving <a href="https://medicaldialogues.in/topics/livers">livers </a>and <a href="https://medicaldialogues.in/topics/kidneys">kidneys </a>and is undergoing trials for hearts, but it hasn't been widely studied for lung preservation," said Jennekens.</div><div style="text-align: justify;">Ex vivo lung perfusion (EVLP) is an established method that allows donor lungs to be preserved and evaluated outside the body before transplantation. The lungs are connected to a pump and ventilator, perfused with a physiological fluid, and sometimes reconditioned. Typically, donor lungs are transported on ice, then warmed to 37°C for functional testing using normothermic EVLP (nEVLP), before being returned to ice until transplantation.</div><div style="text-align: justify;">The UMC Utrecht’s HOPE protocol improves upon this process by eliminating the second cooling phase. After an hour of nEVLP, lungs are maintained at 12°C until transplantation. In a comparison of 12 cases using the nEVLP-HOPE protocol with 118 historical cases of direct lung transplantation without perfusion, no lungs in the HOPE group were rejected. Short-term outcomes were comparable between the two groups.</div><div style="text-align: justify;">“Our results confirm that HOPE is a safe and effective preservation method following normothermic EVLP,” Jennekens said. The next step, according to Jennekens, is determining which preservation strategy works best for specific types of donor lungs, paving the way for future optimization of donor lungs with targeted therapies.</div><div style="text-align: justify;">References: Park, Chanmin; Ko, Yong Jae; Kim, Hee Youn; Sagas, Michael; Eddosary, Melfy, Social Behavior and Personality: an international journal, 2016</div><div></div></div>

430. A New Book on Biomaterials Launched to Revolutionize Orthopaedic and Trauma Treatment

     Tue, 29 Apr 2025 02:30:58 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284860-orthopedic-trauma.webp' /><p style="text-align: justify; "><span style="background-color: rgb(255, 255, 255);">India:&nbsp;</span>The book "<i>Biomaterials in Orthopaedics &amp; Trauma: Current Status and Future Trends in Revolutionizing Patient Care"</i>&nbsp;has been launched, published by Springer Nature.</p><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">Edited by Dr. Raju Vaishya, an orthopaedic surgeon at Indraprastha Apollo Hospitals, New Delhi and academic leader known for his pioneering work in joint replacement and musculoskeletal research, and Dr. Sourabh Ghosh, professor and head of the Regenerative Engineering Laboratory at IIT Delhi, this unique book on a novel topic provides a comprehensive and forward-looking exploration of biomaterials in clinical practice.</div><div style="text-align: justify; ">Biomaterial is a substance, either natural or synthetic, designed to interact with biological systems for medical applications, such as treating, augmenting, or replacing tissues, organs, or bodily functions. Highlighting the importance of biomaterials in transforming musculoskeletal care, Dr. Vaishya shared with Medical Dialogues,</div><div style="text-align: justify; ">“Biomaterials—engineered substances designed to interact with biological systems—are now indispensable in repairing fractured bones, replacing joints, and supporting tissue regeneration. Their evolution has dramatically improved patient outcomes, reduced recovery times, and enhanced the quality of life for millions worldwide.”</div><div style="text-align: justify; ">The book distinguishes itself by combining fundamental principles with practical clinical applications, offering readers an in-depth understanding of the mechanical, chemical, and biological properties of biomaterials. It covers a wide range of applications, including implants, prosthetics, bone scaffolds, and tissue engineering, while also delving into strategies for improving implant integration and longevity.</div><div style="text-align: justify; ">Speaking about the uniqueness of the book, Dr. Sourabh Ghosh noted, “Our volume not only captures the established knowledge but also examines innovations such as novel alloy compositions, advanced surface treatments, and the exciting potential of smart materials that dynamically interact with the body. We have placed significant emphasis on emerging trends like bioactive and biodegradable materials, 3D printing, additive manufacturing, and regenerative medicine.”</div><div style="text-align: justify; ">Targeted at orthopaedic and trauma surgeons, biomedical researchers, healthcare professionals, students, and industry experts, the book serves as a vital resource for anyone keen to stay at the forefront of clinical innovation and biomaterials science. “Biomaterials in Orthopaedics &amp; Trauma," is more than a reference—it is a roadmap for the future of patient care, bridging the gap between cutting-edge materials science and clinical excellence,” Dr. Vaishya added.</div><div style="text-align: justify; ">The book is now available through Springer, Singapore, and is poised to become an essential guide in revolutionizing orthopaedic and trauma care globally.</div><div style="text-align: justify; ">Reference:</div><div style="text-align: justify; ">Vaishya R, Ghosh S. Biomaterials in Orthopaedics and Trauma: Current Status and Future Trends in Revolutionizing Patient Care. Springer, Singapore. April 2025. DOI: https://doi.org/10.1007/978-981-96-3017-2</div></div>

431. AI-Powered ECG Model Shows Promise in Heart Failure Risk Prediction: JAMA

     Tue, 29 Apr 2025 02:30:50 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/03/17/278873-heart-failure-3.webp' /><p style="text-align: justify; ">A new study published in the <i>Journal of American Medical Association</i>&nbsp;showed that a noise-adapted AI-ECG model successfully estimated heart failure risk using only lead I ECGs across diverse multinational cohorts. This suggests a potential strategy for heart failure (HF) risk stratification that could be applied using wearable and portable ECG devices, warranting further prospective studies.</p><p style="text-align: justify; ">Single-lead electrocardiograms (ECGs) may be recorded using portable equipment, which might allow for extensive community-based risk assessment. Thus, to determine if an artificial intelligence (AI) system can predict heart failure risk from noisy single-lead electrocardiograms, Lovedeep Dhingra and colleagues carried out this investigation.</p><p style="text-align: justify; ">A retrospective cohort analysis assessed persons without heart failure at baseline from UK Biobank, YNHHS, and ELSA-Brasil, utilizing outpatient ECG data. The data were evaluated between September 2023 and February 2025, with the major exposure being the AI-ECG-predicted risk of left ventricular systolic dysfunction (LVSD).</p><p style="text-align: justify; ">Lead I ECGs were separated to mimic wearable device signals, and a noise-adaptive AI-ECG model trained to identify LVSD was used. The model's relationship with new-onset heart failure (first HF hospitalization) was investigated. Its predictive ability was compared to the PREVENT and PCP-HF risk scores using the integrated discrimination improvement, Harrell C statistic, and net reclassification improvement.</p><p style="text-align: justify; ">Baseline ECGs were obtained from 192 667 YNHHS patients, 42 141 UKB participants, and 13 454 ELSA-Brasil participants. 31 (0.2%) in ELSA-Brasil, 46 (0.1%) in UKB, and 3697 (1.9%) in YNHHS experienced heart failure over a median (IQR) of 4.2 (3.7-4.5) years, 3.1 (2.1-4.5) years, and 4.6 (2.8-6.6) years, respectively.</p><p style="text-align: justify; ">Regardless of age, sex, comorbidities, or competing risk of mortality, a positive AI-ECG screening result for LVSD was linked to a 3- to 7-fold increased risk for HF, and every 0.1 increase in the model likelihood was linked to a 27% to 65% greater hazard across cohorts. The discrimination of AI-ECG for new-onset HF was 0.828 in ELSA-Brasil, 0.723 in YNHHS, and 0.736 in UKB.</p><p style="text-align: justify; ">Across cohorts, integrating AI-ECG predictions beside PCP-HF and PREVENT equations resulted in a higher Harrel C statistic. AI-ECG improved integrated discrimination by 0.091 to 0.205 vs PCP-HF and 0.068 to 0.192 vs PREVENT, as well as net reclassification by 18.2% to 47.2% vs PCP-HF and 11.8% to 47.5% vs PREVENT.</p><p style="text-align: justify; ">Overall, a noise-adapted AI-ECG model predicted HF risk using lead I ECGs across global cohorts, indicating a viable HF risk-stratification technique that needs to be studied prospectively employing wearable and portable ECG devices.</p><p style="text-align: justify; ">Source:</p><p style="text-align: justify; ">Dhingra, L. S., Aminorroaya, A., Pedroso, A. F., Khunte, A., Sangha, V., McIntyre, D., Chow, C. K., Asselbergs, F. W., Brant, L. C. C., Barreto, S. M., Ribeiro, A. L. P., Krumholz, H. M., Oikonomou, E. K., &amp; Khera, R. (2025). Artificial intelligence-enabled prediction of heart failure risk from single-lead electrocardiograms. JAMA Cardiology. <a href="https://jamanetwork.com/journals/jamacardiology/article-abstract/2832555" rel="nofollow">https://doi.org/10.1001/jamacardio.2025.0492</a></p>

432. FAGR Outperforms Fibrinogen in Predicting Mortality in STEMI Patients: Study Finds

     Tue, 29 Apr 2025 02:30:05 -0000

     <img src='https://medicaldialogues.in/h-upload/2023/05/29/210689-stemi.webp' /><p style="text-align: justify; "><strong>China</strong>: A recent study has highlighted the potential role of the fibrinogen-to-albumin-to-globulin ratio (FAGR) as a prognostic marker in patients with<a href="https://medicaldialogues.in/topics/st-elevation-myocardial-infarction"> ST-elevation myocardial infarction (STEMI) </a>undergoing emergency<a href="https://medicaldialogues.in/topics/percutaneous-coronary-intervention-pci"> percutaneous coronary intervention (PCI)</a>.</p><div class="pasted-from-word-wrapper"><p style="text-align: justify; ">The findings, published in<a href="https://medicaldialogues.in/topics/scientific-reports"> </a><em><a href="https://medicaldialogues.in/topics/scientific-reports">Scientific Reports</a>,</em> indicate that FAGR proved to be a significant predictor of all-cause and cardiovascular mortality in patients with acute STEMI undergoing emergency PCI. A higher FAGR was associated with increased mortality rates, outperforming fibrinogen in prognostic accuracy (ROC curve of 0.720 for all-cause mortality and 0.726 for cardiovascular mortality), highlighting its potential as a valuable prognostic marker in STEMI patients. </p><p style="text-align: justify; ">STEMI is a life-threatening condition that requires immediate medical intervention to restore blood flow to the heart. Despite advancements in PCI, patient outcomes vary significantly, necessitating the identification of reliable prognostic indicators. The researchers note that while the fibrinogen-to-albumin-to-globulin ratio has been recognized for its association with coronary artery disease (CAD), its role in acute STEMI remains insufficiently explored. To bridge this gap, Lixing Chen, Department of Cardiology, Kunming Medical University First Affiliated Hospital, Kunming, Yunnan Province, China, and colleagues aimed to assess the prognostic potential of FAGR in STEMI patients. </p><p style="text-align: justify; ">For this purpose, the researchers enrolled 1,042 STEMI patients who underwent emergency PCI at the First Affiliated Hospital of Kunming Medical University between June 2018 and January 2023. Based on the median FAGR (2.44), patients were categorized into low and high FAGR groups. The predictive value of FAGR for all-cause and cardiovascular mortality was assessed using Kaplan–Meier plots, restricted cubic spline regression, Cox survival analyses, and time-dependent ROC analyses. </p><p style="text-align: justify; ">The key findings of the study were as follows:</p><ul><li style="text-align: justify; ">Kaplan–Meier analysis showed a higher cumulative incidence of all-cause and cardiovascular mortality in the high FAGR group.</li><li style="text-align: justify; ">Multivariate Cox proportional hazard analysis identified FAGR as an independent predictor of all-cause and cardiovascular death.</li><li style="text-align: justify; ">For all-cause mortality, FAGR demonstrated a stronger predictive value (AUC = 0.720) compared to fibrinogen (AUC = 0.687).</li><li style="text-align: justify; ">FAGR outperformed fibrinogen for cardiovascular mortality in prediction accuracy (AUC = 0.726 vs. 0.698).</li></ul><p style="text-align: justify; ">The findings suggest that FAGR is a valuable prognostic indicator in STEMI patients undergoing emergency PCI. According to the authors, the study, the first to report its prognostic significance in STEMI, demonstrated that patients with a higher FAGR had greater all-cause and cardiovascular mortality than those with a lower FAGR. Moreover, FAGR emerged as an independent predictor of mortality, showing superior predictive accuracy compared to fibrinogen.</p><p style="text-align: justify; ">"However, as a single-center retrospective study, it has limitations, including potential data bias despite adjustments for confounding factors. Further prospective research is needed to validate these findings and establish FAGR's role in clinical practice," the authors concluded.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Yang, S., Zhou, Y., Xu, D., Dong, Y., Tang, H., Jing, P., Lu, Y., Yuan, M., Zhao, Z., &amp; Chen, L. (2025). The associations between the FAGR and all-cause and cardiovascular mortality in patients with STEMI. Scientific Reports, 15(1), 1-9. https://doi.org/10.1038/s41598-025-93951-0</p><p style="text-align: justify; "> </p></div><p style="text-align: justify; "><br></p>

433. Ultra-Processed Foods Dominate U.S. Grocery Carts, Raising Health Concerns: Study Shows

     Tue, 29 Apr 2025 02:30:00 -0000

     <img src='https://medicaldialogues.in/h-upload/2025/04/29/284867-mdtv-2025-04-29t123831969.webp' /><div class="pasted-from-word-wrapper"><div style="text-align: justify; ">Nearly half of all grocery purchases in the U.S. are <a href="https://medicaldialogues.in/topics/ultra-processed-foods">ultra-processed foods</a> (UPFs), raising alarms among public health experts. A new study published in <i><a href="https://medicaldialogues.in/topics/Public-Health-Nutrition">Public Health Nutrition</a></i> analyzed over 33 million food items bought by 59,939 American households in 2020, using the NOVA classification system to assess levels of food processing.</div><div style="text-align: justify;">The research found that 48% of packaged food and 38% of beverages were UPFs—foods heavily engineered with additives and ingredients rarely used in home cooking. These included soft drinks, snacks, mixed dishes, and soups. While whole foods like fruits and vegetables had minimal UPFs, they made up only a small share (12%) of overall purchases.</div><div style="text-align: justify;">Purchases of UPFs were highest among non-Hispanic white households (49%), followed by Black (47%), Hispanic (46%), and other ethnic groups (43%). Households with lower income and lower education levels also bought more UPFs, regardless of race. This suggests persistent socioeconomic and racial disparities in <a href="https://medicaldialogues.in/topics/diet">diet </a>quality.</div><div style="text-align: justify;">“Carbonated beverages topped the list for UPF content at 90%, followed by soups and mixed dishes (81%), and snacks and sweets (71%).” Meanwhile, dairy beverages and fruit juices showed significant variation between racial groups.</div><div style="text-align: justify;">Importantly, the study only captured in-home purchases, potentially underrepresenting beverage consumption—especially among non-Hispanic Black households, who may buy more sugary drinks outside the home.</div><div style="text-align: justify;">The findings highlight the pervasive role of UPFs in American diets and point to the need for federal policy action. Unlike countries that have begun regulating food processing and marketing, the U.S. lacks nationwide measures to limit UPF consumption.</div><div style="text-align: justify;">Researchers urge stronger policies to reduce UPF intake and promote healthier diets, especially in vulnerable communities disproportionately affected by chronic diseases linked to ultra-processed foods.</div><div style="text-align: justify;">Reference: Exploring disparities in the proportion of ultra-processed foods and beverages purchased in grocery stores by US households in 2020. Dunford, E.K., Miles, D.R., Popkin, B.M. Public Health Nutrition (2025). DOI: 10.1017/S1368980025000606, https://www.cambridge.org/core/journals/public-health-nutrition/article/exploring-disparities-in-the-proportion-of-ultraprocessed-foods-and-beverages-purchased-in-grocery-stores-by-us-households-in-2020/845F4FA3CCBAEC37A3CA9124AE0538AD</div><div></div></div>

434. Maternal childhood trauma may lead to early metabolic changes in male children: Study

     Mon, 28 Apr 2025 18:15:17 -0000

     <img src='https://medicaldialogues.in/h-upload/2024/05/04/237473-infant-0.webp' /><p style="text-align: justify; ">Adverse situations experienced by the mother during childhood-such as neglect or physical, psychological or sexual violence-can trigger excessive weight gain in male children as early as the first two months of life. This was shown in a study that followed 352 pairs of newborns and their mothers in the cities of Guarulhos and São Paulo, Brazil. The results were published in the journal <i>Scientific Reports</i>. </p><p style="text-align: justify;">The analyses indicated the occurrence of very early metabolic alterations in babies that not only led to weight gain above that expected for their age but also have the potential to increase the future risk of developing obesity and diabetes. </p><p style="text-align: justify;">This is the first article resulting from a Thematic Project supported by FAPESP and the National Institutes of Health (NIH) in the United States. Using a database of 580 vulnerable pregnant women, the group is studying intergenerational trauma, i.e., negative effects that can be passed on to future generations, even if the offspring have not lived through such experiences. </p><p style="text-align: justify;">Conducted by researchers from Columbia and Duke Universities, both in the United States, and the School of Medicine of the Federal University of São Paulo (EPM-UNIFESP) in Brazil, the study focuses on issues related to mother-baby interaction, development, and mental and physical health. </p><p style="text-align: justify;">“We observed that although the babies were born weighing within the expected parameters, in the first few days of life they showed altered weight gain, far above what’s recommended as ideal by the World Health Organization [WHO],” says Andrea Parolin Jackowski, professor at UNIFESP and coordinator of the project in Brazil. </p><p style="text-align: justify;">According to the WHO, the ideal weight gain in the first stage of life is up to 30 grams per day. However, the male babies in the study had an average weight gain of 35 grams per day – with some gaining up to 78 grams per day. </p><p style="text-align: justify;">“The babies who took part in the study were born full-term, healthy and within the ideal weight range. All of the pregnancies we followed were low-risk, but our data showed that every adversity the mother experienced during childhood increased the babies’ weight gain by 1.8 grams per day. And this was limited to males,” the researcher reports. </p><p style="text-align: justify;">According to Jackowski, there are many factors that can influence a baby’s weight in early life, and maternal childhood trauma appears to be one of them. For this reason, the analysis took care to control for so-called confounders – variables related to the mothers’ stress levels that could influence the results. Some examples include lifetime trauma experiences (the effects of which are cumulative) and current trauma, as well as education level and socioeconomic status. </p><p style="text-align: justify;">“It’s also important to note that 70% of the babies who took part in the study were exclusively breastfed. The other 30% were on mixed feeding [a combination of breast milk and formula]. This means that they weren’t eating filled cookies or other foods that could actually change their weight. Therefore, the results suggest the occurrence of an early metabolic alteration in these babies,” she says. </p><h3 style="text-align: justify; ">Why only boys? </h3><p style="text-align: justify;">According to the researcher, maternal trauma during childhood only had an impact on the weight of male babies because of physiological variations in the placenta associated with the sex of the fetus. </p><p style="text-align: justify;">The placenta is a temporary organ composed of maternal and fetal tissue that shows structural differences and differences in the regulation and expression of steroids and proteins depending on the sex of the baby. “Male fetuses develop strategies to maintain constant growth in the face of an adverse intrauterine environment, leading to a greater risk of prematurity and fetal death,” explains the researcher. </p><p style="text-align: justify;">In addition, she adds, childhood adversity is known to increase the risk of depression and anxiety during pregnancy, which can lead to increased levels of pro-inflammatory cytokines and cortisol in the intrauterine environment. “It appears that the placenta of female fetuses adapts to protect them, slowing down the growth rate without restricting intrauterine growth [i.e., the size of the baby is within the expected range at the end of pregnancy] and allowing for a higher survival rate,” she explains. </p><p style="text-align: justify;">Another important issue is that the placenta of male fetuses tends to be more susceptible to fluctuations in substances and metabolites present in the maternal bloodstream compared to female placentas. “As a result, in these cases of trauma, it can become more permeable, causing the male fetus to be more exposed to inflammatory factors resulting from high levels of stress, such as cortisol and interleukins, for example.” </p><p style="text-align: justify;">The work now published is the first to identify intergenerational trauma as a trigger for physical changes at such an early age. “It’s already known that adverse events in the mother’s childhood can trigger psychological and developmental problems, but our study is pioneering in showing that they can affect physical problems, such as weight gain, as early as the first two months of life,” says Jackowski. </p><p style="text-align: justify;">Now, the research team, which includes Vinicius O. Santana and FAPESP postdoctoral fellow Aline C. Ramos, will follow the weight development of the children of mothers who suffered adversity in childhood until they are 24 months old. “We’re going to follow them for longer because we want to investigate the impact of the introduction of food, which usually occurs at 6 months of age,” she says. </p><p style="text-align: justify; ">As the researchers explain, the research suggests that metabolic changes can be modified. “It’s not a matter of determinism. We need to monitor how the metabolism and inflammatory factors behave in these babies over a longer period of time to understand how to modulate this process. It’s important to know that all of this is modifiable, and we’re now going to look at how we can intervene,” she says.</p><p style="text-align: justify; ">Reference:</p><p style="text-align: justify; ">Santana, V.O., Ramos, A.C., Cogo-Moreira, H. et al. Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort. Sci Rep 15, 2960 (2025). https://doi.org/10.1038/s41598-025-87078-5.</p>

435. Teen Faces Liver-Kidney Transplant With Positivity and Grit

     Wed, 30 Apr 2025 15:00:00 -0000

     

     Celebrating multiorgan transplant recipients during Donate Life Month.

     <div><img width="768" height="433" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Marlow making a heart with her hands" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-450x254.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-900x507.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-768x433.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <p><em>Celebrating multiorgan transplant recipients during Donate Life Month</em></p> <figure class="wp-block-image size-large"><img decoding="async" width="900" height="507" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-900x507.jpg" alt="Marlow making a heart with her hands" class="wp-image-27302" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-900x507.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-450x254.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1-768x433.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-heart-1200x675-1.jpg 1200w" sizes="(max-width: 900px) 100vw, 900px" /></figure> <p>Despite having kidney disease since she was young, Marlow Hoel, age 14, has always had tons of energy and a good attitude. Her family knew she would need a kidney transplant, but even after she learned that her liver was failing as well, Marlow’s happy-go-lucky mindset stuck.</p> <p>“Marlow has always remained positive. She never felt an energy change from before or after the transplant. Her doctors couldn’t believe she was doing as well as she was with both organs failing,” says her mom, Leah.</p> <p>Marlow was born with a rare type of <a href="https://www.stanfordchildrens.org/en/topic/default?id=polycystic-kidney-disease-90-P03107">polycystic kidney disease</a> where cysts form on the kidneys and can also form on the liver. Her kidneys were slowly failing as she grew.</p> <h2 class="wp-block-heading">Coming to Stanford Children’s for a liver-kidney transplant</h2> <p></p> <p>In 2021, when Marlow was 11 years old, the Oregon family came to <a href="https://www.stanfordchildrens.org/en.html">Stanford Medicine Children’s Health</a> for a transplant evaluation, which showed a need for kidney transplant but not an immediate one. In 2023, they returned because her kidney markers were worsening and she was reevaluated and placed on the active donor waiting list.</p> <p>“At that time, our <a href="https://www.stanfordchildrens.org/en/services/liver-transplant/careteam.html">liver transplant team</a> took a second look and determined that she needed a <a href="https://www.stanfordchildrens.org/en/services/liver-transplant.html">liver transplant</a> as well,” says <a href="https://www.stanfordchildrens.org/en/services/kidney-transplant/care-team-members.html">Gerri James, RN, BSN</a>, transplant coordinator.</p> <p>Marlow was put on the active waiting list for both organs. Multiorgan transplants can involve a longer wait than single organs. Luckily, her kidneys and liver were working well enough that she didn’t need dialysis and was able to go home and wait.</p> <p>“Since early on when we first talked about transplant, I knew I wanted Marlow to go to Stanford Children’s,” Leah says. “We were impressed by the volumes of kidney and liver transplants that they do, and it was important for us to go somewhere that frequently performs transplants.”</p> <p>The <a href="https://www.stanfordchildrens.org/en/services/kidney-transplant.html">Kidney Transplant Program</a> at Stanford Children’s is No. 1 in the country for volumes, with excellent outcomes. The <a href="https://www.stanfordchildrens.org/en/services/liver-transplant.html">Pediatric Liver Transplant Program</a> is also one of the busiest in the country, offering several types of transplants and implementing the latest innovations to improve outcomes.</p> <h3 class="wp-block-heading">Getting the call that a donated kidney and liver were available</h3> <p>The family waited just over a year for the call that would change Marlow’s life. “You can do all you want to prepare for that phone call, but you never expect it when it actually happens,” Leah says.</p> <p>Marlow describes the timing as divine because the call came just two days before the end of the school year. The Oregon family quickly arranged to get to Stanford Children’s within 24 hours so the multiorgan transplant could take place the day after arrival.</p> <p>“I just wanted the transplant to happen over summer break so I wouldn’t miss volleyball in the fall,” says Marlow, whom her mom calls a talented all-around athlete.</p> <h3 class="wp-block-heading">Undergoing a multiorgan transplant at Stanford Children’s</h3> <p>A large team of experts participated in preoperative huddles to plan out the details of Marlow’s surgery and prepare for every scenario so they could act quickly in the moment to ensure the best possible outcome. Experts included <a href="https://www.stanfordchildrens.org/en/services/kidney.html">nephrologists</a> (kidney specialists), <a href="https://www.stanfordchildrens.org/en/services/gastroenterology-hepatology-nutrition/hepatology.html">hepatologists</a> (liver doctors), <a href="https://www.stanfordchildrens.org/en/services/transplant/team.html">transplant surgeons</a>, specialized transplant <a href="https://www.stanfordchildrens.org/en/for-health-professionals/nursing.html#toppick">nurses</a>, and the family.</p> <p>Marlow’s new kidney and liver came from the same donor, which is beneficial. “The liver is immune protective for the kidney, so the rejection rate is lower than taking the organs from two different donors,” says <a href="https://www.stanfordchildrens.org/en/doctor/varvara-a-kirchner.html">Varvara Kirchner, MD</a>, Marlow’s kidney and liver transplant surgeon.</p> <p>Dr. Kirchner teamed up with <a href="https://www.stanfordchildrens.org/en/doctor/marc-l-melcher.html">Marc Melcher, MD, PhD</a>, chief of Abdominal Transplantation at Stanford Children’s, to perform Marlow’s multiorgan transplant. Dr. Melcher took out one of Marlow’s worn-out kidneys and liver, and Dr. Kirchner placed Marlow’s new kidney and liver.</p> <p>“Communication and collaboration amongst our large team of experts is key for the success of multiorgan transplants and complex cases. It’s what helps us achieve high-quality outcomes,” Dr. Melcher says. All of the transplant teams within the <a href="https://www.stanfordchildrens.org/en/services/transplant.html">Pediatric Transplant Center</a> at Stanford Children’s work closely together, helping multiorgan transplants run smoothly.</p> <p>In order to provide a liver to two children rather than just one, Dr. Kirchner split Marlow’s donated liver, meaning she got one piece of the liver and a younger child got the other. Doing so helps address the shortage of donor livers available for children in the United States. Remarkably, split livers regrow to fully functional livers.</p> <p>“Less than 10 pediatric transplant centers in the nation split livers, so this made for a more complex operation with added steps, but it was worth it to take care of more children,” Dr. Kirchner says. “We also bring in donor livers on a perfusion pump, which is novel, which preserves their quality.”</p> <p>The transplant surgery went perfectly, with no complications or concerns. Waiting nearly 14 hours from start to finish to see Marlow afterward was hard for the family. “We were the first ones there and the last ones there,” Leah says.</p> <h3 class="wp-block-heading">Marlow powers through recovery</h3> <p>From the minute Marlow woke up, her goal was to recover as fast as possible. Within a few days, a <a href="https://www.stanfordchildrens.org/en/services/physical-therapy.html">physical therapist</a> came to her bedside and gave her homework to complete over the next three days.</p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img decoding="async" width="400" height="500" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-dog-400x500-1.jpg" alt="Marlow with her dog, Arrow" class="wp-image-27296" style="width:297px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-dog-400x500-1.jpg 400w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-dog-400x500-1-360x450.jpg 360w" sizes="(max-width: 400px) 100vw, 400px" /></figure></div> <p>“She got it all done in an hour,” Leah says. “Marlow was a rock star. She hit the road running. She didn’t stop to feel sorry for herself.”</p> <p>“All I wanted to do was walk again—it was hard lying in bed,” Marlow says. “And I just wanted to go home and cuddle my dog, Arrow.”</p> <p>Marlow recalls the kindness of the nurses. One, Mercedes, washed her hair and gave her detangler and hair clips. “I loved the nurses in the <a href="https://www.stanfordchildrens.org/en/topic/default?id=intensive-care-90-P03021">pediatric intensive care</a>. They were all so caring and sweet and kind,” she says.</p> <p>Dr. Kirchner describes Marlow as a very mature teenager who did great with the whole experience. The family describes Dr. Kirchner as their hero.</p> <p>“I saw Marlow outside the hospital afterwards. It was fantastic to see her, as a young teenage girl, getting back to everyday activities,” Dr. Kirchner says. “It’s a special moment when I see my patients recovered and living their normal lives.”</p> <h3 class="wp-block-heading">Going home and returning to her happy, active life</h3> <p>The family had to stay near the hospital after discharge to make sure the transplanted organs were doing well. After six weeks, they were able to go home to Oregon. Marlow took Dr. Melcher’s advice to be as “active as possible after transplant.”</p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img loading="lazy" decoding="async" width="400" height="500" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-volleyball-400x500-1.jpg" alt="Marlow playing volleyball" class="wp-image-27298" style="width:324px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-volleyball-400x500-1.jpg 400w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/marlow-volleyball-400x500-1-360x450.jpg 360w" sizes="auto, (max-width: 400px) 100vw, 400px" /></figure></div> <p>“I went to volleyball camp just two days after I returned home,” Marlow says.</p> <p>Marlow’s wish to return to school in time for the new year came true. It’s been nearly 10 months, and her new liver and kidney are doing great. There are zero signs of rejection, and her labs are all trending in the right direction.</p> <p>“There are no words that describe my gratitude toward the donor family. I put myself in their shoes, having lost a loved one, and I hope I would have the grace they had,” Leah says.</p> <p>Both Dr. Melcher and Dr. Kirchner believe Marlow will do very well in the future. They are pleased that she is back to her active life of volleyball, dance, school, and friends.</p> <p>“The great gift of organ transplant is that Marlow can lead a pretty normal life,” Dr. Melcher says. “It’s a lot for any child to go through, but thankfully there is a big payback when they get through it successfully.”</p> <p><a href="https://www.stanfordchildrens.org/en/services/kidney-transplant.html">Learn more about kidney transplant&gt;</a></p> <p><a href="https://www.stanfordchildrens.org/en/services/liver-transplant.html">Learn more about liver transplant&gt;</a></p>

436. Major Milestones in Your Baby’s First Year, Part 2: 6 to 12 Months

     Tue, 29 Apr 2025 21:18:48 -0000

     

     Amina Ahmed, MD, sheds light on significant milestones to expect during your baby’s first year.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Baby and father crawling on floor" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-900x506.jpg" alt="Baby and father crawling on floor" class="wp-image-27309" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/05/baby-milestones-part-2.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p>Your baby’s first year is a period of remarkable change. Over these 12 months, you’ll witness them transform from a tiny bundle into a walking, talking, and interactive little person. In the second part of this two-part series, <a href="https://www.stanfordchildrens.org/en.html">Stanford Medicine Children’s Health</a> pediatrician <a href="https://www.stanfordchildrens.org/en/doctor/a/amina-ahmed.html">Amina Ahmed, MD</a>, continues to guide us through the significant milestones you can expect during your baby’s first year, focusing on months 6 to 12.</p> <h2 class="wp-block-heading">6 to 9 months</h2> <p></p> <p>Your 6-month-old baby is full of exciting changes. One of the major ones is their heightened interest in solid foods and putting things in their mouths. “Six months is a big age for introducing food. Babies will start to really watch their parents eating food,” Dr. Ahmed shared. “They’ll start smacking their own lips. They’ll try to get a bite out of what their parents are eating.”</p> <p>You may even be surprised by how fast they can grab a handful of food from your plate or even a toy—a trait you can use to your advantage during playtime, according to Dr. Ahmed.</p> <p>“If your baby’s on their belly, a great way to play with them is to just put something in front of them and let them work toward it,” she said. “You’ll see they’ll try to take their arm out to try to grab that toy and work toward that toy. Some babies will start lifting their bottom up, getting in a full crawling position, and move back and forth.”</p> <p>By 6 months, your baby should be rolling confidently, and by 7 months, they should be showing signs they are ready to sit up on their own.</p> <p>“At 6 months, if you hold them from their bottom and put them in your lap, they can sit, but they don’t sit independently,” Dr. Ahmed said. “By 7 months, they learn to hold themselves up and start stopping themselves from falling and keeping their arms stretched out.”</p> <p>During this time, your baby will become much more interactive as they find their voice and start learning how to talk.</p> <p>“Language-wise, they enjoy music, enjoy talking back and forth, and blowing raspberries,” Dr. Ahmed said. “They’ll also start experimenting with their voice. So, they’ll squeal high, they’ll squeal low. You’ll hear those sounds of, ‘ah, ah, ah, bah, bah, bah, ma, ma, ma, yeah, yeah, yeah.’ So, a lot more of those sounds start coming up at this point.”</p> <p>Dr. Ahmed explained that babies this age will start to have more understanding and recognition of people around them. They recognize their primary caretaker and have bonded with that person. Some babies past 6 months will even start showing some signs of stranger anxiety. “We see it when they come to the office; they don’t know me, so they will get a little anxious,” she said. “If I get too close, or if I try to pick them up too quickly, they will get a little anxious.&nbsp; This is a very normal response that babies have, and it’s just showing that they’re much more aware of their environment and understanding things around them.”</p> <h3 class="wp-block-heading">9 to 12 months</h3> <p>As your baby moves closer to completing their first trip around the sun, the fun really begins! Your baby is learning how to explore their world in new ways, the first of which is their newfound mobility as they learn how to crawl and stand.</p> <p>“At this point, a lot of babies are starting to crawl, and hence they’re exploring. The houses just open up to them. It’s like a wonderland,” Dr. Ahmed explained. “The pulling to stand is really important because the pulling to stand tells us they have the core strength to kind of come up, you know, and they’re showing that core strength. Even if they’re walking or not, they should be pulling to stand by 12 months.”</p> <p>They should also be able to move things from one hand to the other. “If you give the baby a little rattle or a toy, they will grab it in one hand and move it to the other hand, and they can bring it to their mouth,” Dr. Ahmed said.</p> <p>Now that your baby is on the move, Dr. Ahmed urges parents to start babyproofing their home by getting down on baby’s level to see what your crawling or scooting baby can get into.</p> <p>“They are trying to fine-motorize. They’re becoming very focused on how to pick up things. If you give them a few Cheerios, they will try to pick them up. They will bring their thumb and their finger together to make that pincer grasp. They’ll find the tiniest piece of lint that could barely be seen by the human eye,” she said. “This is how they explore. They will touch. They will put things in their mouth. And hence you have to childproof the house: covering up outlets, not having small things that they can choke on, and doing all those things.”</p> <p>Your little explorer will be curious about everything they see, investigating every surface and seeing what new noises they can make. They may start saying a few words like “Mama” or “Dada” or participating in songs.</p> <p>“If you’re singing a song and you clap with it or other gestures, they’ll mimic that,” Dr. Ahmed said. “They start to understand different gestures. And they’re looking for your response, which is a big reward for the baby. And they’ll keep on doing it. So that’s how you get development going. You really give that big response to what the baby is doing. And they’re like, ‘Oh wow, this is so good. I should do more of it.’”</p> <p>In addition to learning how to say new words, babies can recognize their name and the names of their primary caregivers.</p> <p>It’s natural for parents to occasionally have concerns as they follow their baby’s development. When that happens, Dr. Ahmed encourages parents to check in with their pediatrician. She also wants parents to keep in mind that the most important thing they can do is to simply enjoy their baby.</p> <p>“A lot of what we naturally do fosters normal development. So, just providing that supportive environment is all they need. Nature has geared the baby to do all these things, and they will start going to the next level on their own. It’s about providing opportunities,” she said. “You don’t have to spend hours and hours on development. I encourage parents to just spend time with their baby. It helps you bond. It will also help you relax. It will help the child development.”</p> <p>To learn more about your baby’s milestones from newborn to 5 months, read <a href="https://healthier.stanfordchildrens.org/en/major-milestones-baby-first-year/">part 1</a>.</p>

437. Stars Align to Bring Kidney Donor and Recipient Together

     Fri, 25 Apr 2025 15:00:00 -0000

     

     Celebrating National Donate Life Month at Stanford Medicine Children’s Health.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Sumi and her family" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <p><em>Celebrating National Donate Life Month at Stanford Medicine Children’s Health</em></p> <p>In one day, Aubrey Brazier, age 15, went from perfectly healthy to suddenly needing a kidney transplant. She was living her best life as a sophomore in high school when she underwent a sports physical for the bowling team. During the exam, the doctor discovered extremely high blood pressure.</p> <p>“It was heart attack or stroke level high,” says Aubrey.</p> <p>Because she had no history of high blood pressure or any other medical condition, her mother immediately took her to a hospital near their home in Las Vegas for more tests, which revealed stage four kidney failure. “It all happened so quickly. We were like, ‘What? How can this be?’ Her life changed overnight,” says her mom, Tiffany.</p> <p>Donor kidneys are not easily available, and finding one for Aubrey was even harder. She required a rare donor match because she was highly sensitized, meaning her body would reject most donors’ organs. Normally, finding such a match can take several months or even years.</p> <p>Hope came in the form of Sumi Wideman, a neonatal intensive care nurse who lived thousands of miles away in California. Everything lined up just right to bring Sumi and Aubrey together.</p> <p>“It was divine, and we are so grateful for Sumi’s compassion and kindness, and for the entire team at Stanford Children’s Pediatric Transplant Center,” Tiffany says.</p> <h2 class="wp-block-heading">Coming to Stanford Children’s for kidney transplant care</h2> <p></p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img loading="lazy" decoding="async" width="350" height="691" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-350x691jpg.jpg" alt="Tiffany, Aubrey, and Sumi" class="wp-image-27272" style="width:253px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-350x691jpg.jpg 350w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-350x691jpg-228x450.jpg 228w" sizes="auto, (max-width: 350px) 100vw, 350px" /><center><figcaption class="wp-element-caption">Tiffany, Aubrey, and Sumi</figcaption></center></figure></div> <p>Aubrey’s local nephrologist made Tiffany aware of several <a href="https://www.stanfordchildrens.org/en/services/kidney-transplant.html">pediatric kidney transplant</a> programs, and after one phone call, she knew she wanted Aubrey to go to Stanford Medicine Children’s Health—one of the top programs in the nation. The Stanford Children’s <a href="https://www.stanfordchildrens.org/en/services/transplant.html">Pediatric Transplant Center</a> is No. 1 in the United States in kidney transplant volumes for children 18 years and younger.</p> <p>Once evaluated at Stanford Children’s, Aubrey was listed with the <a href="https://unos.org/" target="_blank" rel="noreferrer noopener">United Network for Organ Sharing</a> (UNOS), which tracks organ donation across the country. Her kidneys were barely functioning, but luckily they were working well enough that she didn’t need <a href="https://www.stanfordchildrens.org/en/services/dialysis.html">dialysis</a>.</p> <p>Aubrey and Tiffany returned home to wait for that life-changing call that a donor organ had been found, surrounded by loving friends and family, including her two older brothers. Less than six months later, <a href="https://www.stanfordchildrens.org/en/services/kidney-transplant/care-team-members.html">Gerri James, RN, BSN</a>, transplant coordinator, called. She told Tiffany, “I don’t have a kidney from UNOS (the deceased donor pool), but I have a stranger who wants to donate.”</p> <p>“I was so surprised and speechless, because it was so unexpected. My heart was overjoyed. I thought, who is this person and how has it been put on their heart to want to do this? I cried and thanked God,” Tiffany says.</p> <h3 class="wp-block-heading">Needing a very rare and special donor</h3> <p><a href="https://www.stanfordchildrens.org/en/doctor/thomas-a-pham.html">Thomas Pham, MD</a>, surgical director of Pediatric Kidney Transplant at Stanford Children’s, knew it would be a challenge to find Aubrey a good match. “Aubrey has the most difficult blood type to match, and she had developed antibodies against 85% of the population.”</p> <p>She received several deceased donor offers from UNOS, but they were incompatible, so when Sumi stepped forward, the <a href="https://www.stanfordchildrens.org/en/services/kidney-transplant/careteam.html">kidney transplant care team</a> thought of the National Kidney Registry’s <a href="https://www.kidneyregistry.com/for-patients/paired-kidney-exchange/" target="_blank" rel="noreferrer noopener">Paired Kidney Exchange</a>. It’s an ingenious system where a person who is incompatible with you donates a kidney on your behalf to someone else in exchange for a compatible kidney for you. The exchange widens the pool and helps doctors find more precise matches, which was crucial for Aubrey. A good match lowers the risk of rejection and potential side effects and helps the kidney last much longer.</p> <p>Stanford Children’s is very thoughtful about personalizing kidney donation to each individual’s needs to achieve good outcomes. They think beyond the transplant itself and consider quality of life and the big picture for years to come.</p> <p>“Every child will need more kidney transplants in the future, but we want the first to be such good quality that they don’t need one for a long way down the road,” Dr. Pham says.</p> <p>All kidney donations, including from deceased donors, are wonderful gifts. However, research shows living donor kidneys tend to last longer.</p> <p>“Sumi was originally planning to donate to a friend’s child, but another match was found. At that point, a lot of people might stop the process, but she still wanted to donate. That’s an incredible gift,” says <a href="https://www.stanfordchildrens.org/en/doctor/marc-l-melcher.html">Marc Melcher, MD, PhD</a>, chief of Abdominal Transplantation at Stanford Children’s.</p> <p>There are about 100,000 people and 1,200 children on the U.S. waiting list for a kidney, according to <a href="https://www.stanfordchildrens.org/en/doctor/paul-c-grimm.html">Paul Grimm, MD</a>, Aubrey’s pediatric nephrologist. In 2024, only 827 children received a kidney transplant in the U.S., according to the Organ Procurement and Transplantation Network. Most children get a kidney in one to two years, but for those who are sensitized, like Aubrey, they will wait much longer.</p> <h3 class="wp-block-heading">Donating to a complete stranger as a living donor</h3> <p>When asked to consider donating one of her kidneys to her friend’s son, Sumi was all in. When that fell through, she recalls thinking, ‘It doesn’t have to be him. I can help another child.’</p> <p>“It didn’t seem like a big decision. If my child needed a kidney, I would hope someone would come forward,” she says.</p> <p>Sumi downplays her donation, saying that Stanford Children’s made it easy by scheduling her evaluation on one day and running the operation smoothly. She wonders why more people don’t donate.</p> <p>“I’ve had surgery before, so it wasn’t very nerve-racking. The hospital is top of the line, and everyone was great. I was walking around and driving within a few weeks, and I didn’t have hardly any pain,” she says. Living kidney donors typically do not have any future restrictions besides taking good care of their remaining kidney.</p> <p>According to the <a href="https://www.kidneyregistry.com/" target="_blank" rel="noreferrer noopener">National Kidney Registry</a>, 6,000 people donate a kidney in the United States every year. Of those, only 5% donate to strangers. They’re called Good Samaritan donors—the perfect name for Sumi.</p> <p>“I just think that we need to put more good in the world,” she says. She recalls noticing how some people were uncaring toward others during the COVID-19 pandemic. “That bothered me. I thought if I did something kind, it might negate some of that. Giving my kidney to Aubrey helped heal that for me.”</p> <h3 class="wp-block-heading">Undergoing a successful kidney transplant</h3> <p>The two had their transplant surgeries on the same day. Sumi’s kidney was rushed to a waiting patient across the country, and Aubrey’s kidney was waiting for her from another generous donor. The surgeries went without a hitch. Stanford Children’s offers minimally invasive surgery to most kidney donors, helping to reduce recovery time and scarring.</p> <p>While the transplant surgery is important, empowering families and children to care for their new kidney afterward is just as important. Tiffany is extremely grateful for the thorough pretransplant prep the family received beforehand and the support they are receiving still today.</p> <p>“At Stanford Children’s, it is not just the surgeons and pretransplant preparation that are great, it is also the posttransplant care—our advanced practice practitioners who live and breathe transplant, the nutritionists, and how we collaborate with local doctors,” Dr. Grimm says. “It all adds up to why our kidney transplant outcomes are always one of the top in the nation.”</p> <figure class="wp-block-image aligncenter size-large is-resized"><img loading="lazy" decoding="async" width="375" height="500" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-375x500-1.jpg" alt="Tiffany meets Sumi" class="wp-image-27276" style="width:308px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-375x500-1.jpg 375w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-375x500-1-338x450.jpg 338w" sizes="auto, (max-width: 375px) 100vw, 375px" /><center><figcaption class="wp-element-caption">Tiffany (mother of patient) meets Sumi, who helped get a kidney for her daughter’s transplant</figcaption></center></figure> <h3 class="wp-block-heading">Meeting her kidney donor</h3> <p>Aubrey, Tiffany, and Sumi are no longer strangers. Aubrey wanted to meet the generous donor who changed her life so completely. The big day came when both returned for a follow-up visit shortly after surgery.</p> <p>“There was not a dry eye in the clinic,” Gerri James says. “Even though Sumi’s kidney went to someone else, we all say Aubrey has Sumi’s kidney.”</p> <p>The two shared a full-circle moment when Aubrey realized that Sumi was a nurse—something she wants to be when she grows up. She had asked her mom right beforehand, “Wouldn’t it be cool if she is a nurse?”</p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img loading="lazy" decoding="async" width="400" height="500" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-400x500-1.jpg" alt="Sumi and her husband" class="wp-image-27274" style="width:257px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-400x500-1.jpg 400w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donate-400x500-1-360x450.jpg 360w" sizes="auto, (max-width: 400px) 100vw, 400px" /><center><figcaption class="wp-element-caption">Sumi and her husband</figcaption></center></figure></div> <p>“It was wonderful to meet Aubrey,” Sumi says. “She is so kind and bubbly, and I see her making a difference in the world. It feels good to know that she can have a healthy future and do what she wants in life.”</p> <p>The families stay in touch via social media. Tiffany messages Sumi to give her updates, like “Hey, Aubrey started her first job” or “Her biopsy turned out well.”</p> <p>“I want her to know about Aubrey’s life and the immense impact she has had on our lives,” Tiffany says. “Words can’t begin to describe how incredibly thankful and grateful we are for the gracious gift Sumi has given. Her kindness and selflessness has given Aubrey a second chance at life.”</p> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-900x506.jpg" alt="Sumi and her family" class="wp-image-27283" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/kidney-donation-1200x675-2.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /><center><figcaption class="wp-element-caption">Sumi and her family</figcaption></center></figure> <h3 class="wp-block-heading">Taking on life after kidney transplant</h3> <p>Aubrey is back to full speed, just how she likes it. She is now a junior in high school, working at her first job, hanging out with friends, and serving at church in the media and children’s ministry.</p> <p>“I definitely have much more energy and a better quality of life than I had before the transplant,” Aubrey says. “I can do almost everything I want, and my faith and perspective on life has changed. Now, I take life more seriously, and I am treating my body well so my kidney will last the most years it can.”</p> <p>She dreams of becoming a nurse, living a healthy life, having a family of her own one day,&nbsp;and going to Morocco soon with her family, a trip made possible by the Make-A-Wish Foundation. She’s also excited to go to <a href="https://www.stanfordchildrens.org/en/services/transplant/resources.html">Transplant Camp</a> this summer through Stanford Children’s.</p> <p>Sumi recalls reading that organ donors are left with a feeling of well-being. “It’s really true. I feel good all the time. By donating, I also received a gift,” she says.</p> <p><a href="https://www.stanfordchildrens.org/en/services/kidney-transplant/faq-donors.html">Learn more about becoming a kidney donor &gt;</a></p>

438. New Lungs Give Young Girl Her Laugh Back

     Wed, 16 Apr 2025 15:00:00 -0000

     

     Her pulmonary hypertensive crisis was so severe because it was accompanied by flash pulmonary edema, a sudden and severe accumulation of fluid in the lungs.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Sadie smiling" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-900x506.jpg" alt="Sadie smiling" class="wp-image-27206" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-1200x675-1.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p>If you meet 7-year-old Sadie Jackson, the first thing you’ll hear is her laugh. Her mom, Carrie, calls her a “giggler.” It’s full of life and bright, and will bring anyone who hears it joy. But a sudden onset of symptoms and a rare, progressive lung disease took away that giggle.</p> <p>“It got to the point where even laughter would make her sick,” Carrie remembers. “It broke my heart when she would laugh and then start feeling unwell. That was so awful.”</p> <p>In September 2022, when they were living in Southern California, the family was with friends at the zoo, and Sadie’s stomach started to hurt. She was panting and coughing and couldn’t walk the rest of the way to the car.</p> <p>“What we came to learn was that was a pulmonary hypertensive crisis,” Carrie says. “From that point on, she had a crisis every couple of days. She would progressively get worse, so she would thrash about, couldn’t breathe, and turn pale, sweaty, and clammy. Once everything relaxed, she would be back to normal.”</p> <p>After many doctors’ visits, 911 calls, and emergency room trips, it was still unclear exactly what she had until she was admitted to a local children’s hospital. The very next morning, Sadie had another crisis.</p> <p>“I’m a nurse,” Carrie says. “That was the first time I’d seen it on the monitor, so I knew it was bad. I just thought there had to have been angels around us while we were at home.”</p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img loading="lazy" decoding="async" width="450" height="600" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-and-her-mom-carrie-450x600-1.jpg" alt="Sadie in hospital bed with mother Carrie by her side" class="wp-image-27219" style="width:369px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-and-her-mom-carrie-450x600-1.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-and-her-mom-carrie-450x600-1-338x450.jpg 338w" sizes="auto, (max-width: 450px) 100vw, 450px" /><center><figcaption class="wp-element-caption">Carrie and Sadie Jackson</figcaption></center></figure></div> <p>Her pulmonary hypertensive crisis was so severe this time because it was accompanied by flash pulmonary edema, a sudden and severe accumulation of fluid in the lungs, causing severe respiratory distress. This is seen in patients with pulmonary veno-occlusive disease, or PVOD. PVOD is an extremely rare and often fatal form of <a href="https://www.stanfordchildrens.org/en/services/pulmonary-vascular-disease.html">pulmonary hypertension</a> (PH) where the small veins in the lungs become blocked, causing increased pressure in the pulmonary arteries and eventually affecting heart function. There is no cure. </p> <p>“[The doctor] told us that if she had PVOD, it is a ruthless and incredibly aggressive disease. The only treatment is lung transplant, and they would be referring Sadie to the lung transplant program at Stanford Medicine Children’s Health,” Carrie recalls.</p> <p>Stanford Children’s is the only pediatric program in the Western United States that performs lung or combined heart-lung transplants from infancy through early adulthood, offering more than 35 years of experience—more than any other pediatric hospital in the region. Often, those on the waiting list are like Sadie, with significant pulmonary disease from PH and very young.</p> <p>Through a lot of coordination, in January 2023 Sadie was airlifted to Stanford Children’s, where she was evaluated and then listed for a double-lung transplant.</p> <p>“Literature shows us that survival after diagnosis of PVOD, which is after their first presentation, is usually no more than a year,” says <a href="https://www.stanfordchildrens.org/en/provider/laura-green.html">Laura Green, RN</a>, Pediatric Lung and Heart-Lung Transplant program manager. “It’s urgent to assess them for transplant candidacy, given that once approved to be placed on the transplant waiting list, the wait time for matching organs is unpredictable.”<em></em></p> <h2 class="wp-block-heading">Staying positive during a long wait</h2> <p></p> <p>The smaller a patient is, the longer they often wait for a matching donor, due to smaller numbers of infant and pediatric organ donors. Finding the best way to bridge that gap until transplant was crucial.</p> <div class="wp-block-image"> <figure class="alignright size-full is-resized"><img loading="lazy" decoding="async" width="450" height="600" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-with-dr-450x600-3.jpg" alt="" class="wp-image-27232" style="width:360px;height:auto" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-with-dr-450x600-3.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-with-dr-450x600-3-338x450.jpg 338w" sizes="auto, (max-width: 450px) 100vw, 450px" /><center><figcaption class="wp-element-caption">Sadie with Dr. Si and Laura Green</figcaption></center></figure></div> <p>“We started her on diuretic therapies to help remove some of the fluid from her lungs, and started her on steroids,” says <a href="https://www.stanfordchildrens.org/en/doctor/xin-si.html">Cissy (Xin) Si, MD</a>, medical director of the <a href="https://www.stanfordchildrens.org/en/services/lung-transplant.html">Pediatric Lung and Heart-Lung Transplant</a> program. “Not every patient responds, but Sadie was very responsive. That helped her get to a more stable spot.”</p> <p>Sadie also presented a unique challenge because she was sensitized, meaning she had a high level of Human leukocyte antigen (HLA) antibodies that made it harder to find a compatible donor<em>. </em>The lung transplant program was able to successfully desensitize Sadie while she awaited transplant, improving her chances of finding a suitable match.<em></em></p> <p>Despite the challenges, the Jackson family found ways to remain positive, leaning on their faith. Whether it was the transplant psychologist, their social worker, or music therapists, they knew Sadie was in the best hands possible as they prepared her for a rare treatment for her rare disease.</p> <p>“Some people might say, ‘We can’t do lung transplant. The patient is too small,’” says <a href="https://www.stanfordchildrens.org/en/doctor/e/elisabeth-martin.html">Elisabeth Martin, MD</a>, surgical director of Pediatric Lung and Heart-Lung Transplant. “But it’s a treatment. It’s an option we should use for sick patients. Here at Stanford Children’s, all of the teams from <a href="https://www.stanfordchildrens.org/en/services/rehabilitation-services.html">rehabilitation</a> to the <a href="https://www.stanfordchildrens.org/en/services/cardiovascular-intensive-care.html">Cardiovascular Intensive Care Unit</a> to <a href="https://www.stanfordchildrens.org/en/services/pulmonary-medicine-cystic-fibrosis.html">pulmonology</a> align in their roles in taking on a case like this. They have to be at the top of their game, so everything goes smoothly.”</p> <h3 class="wp-block-heading">Back to laughing and playing</h3> <p>In December 2023, 10 months after she was placed on the transplant waiting list for new lungs, Sadie got the call that there was a set of lungs for her. The family was ready. On the day of her surgery, her care team put up a sign on her door reading, “Happy Lung Day!” with personalized notes.</p> <div class="wp-block-image"> <figure class="aligncenter size-full"><img loading="lazy" decoding="async" width="600" height="450" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-happy-lung-day-600x450-1.jpg" alt="The Jackson family on Lung Day" class="wp-image-27217" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-happy-lung-day-600x450-1.jpg 600w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/sadie-happy-lung-day-600x450-1-450x338.jpg 450w" sizes="auto, (max-width: 600px) 100vw, 600px" /><center><figcaption class="wp-element-caption">The Jackson family</figcaption></center></figure></div> <p>“They all genuinely care about Sadie. There’s an emotional investment. It feels like she’s not just a patient. They are her biggest advocate and truly want to see the best outcomes possible for her,” Carrie says.</p> <p>The surgery went smoothly. Today, Sadie is back to playing the violin and piano, singing, and dancing.</p> <p>“It means everything to me. She’ll just run around the house and say, ‘Look how fast I can go!’ She’s just back to herself. I’m so grateful she can give her sister a run for her money and that they can play together,” Carrie says.</p> <p>Carrie is working on a letter to the donor family to express her gratitude and that the donor’s life continues to live on, helping Sadie thrive.</p> <p>“Transplant is life-changing. We are so grateful to the donor, to the Lord Jesus, and to the team at Stanford Children’s who walked with us through this whole thing. I would encourage anyone to learn more about becoming an organ donor. You could make a world of difference in somebody’s life.”</p> <hr class="wp-block-separator has-alpha-channel-opacity is-style-dots"/> <p>Lucile Packard Children’s Hospital Stanford is nationally ranked No. 10 in pulmonology by U.S. News &amp; World Report and has performed 57 bilateral double lung transplants and 42 combined heart-lung transplants since 1986. <a href="https://www.stanfordchildrens.org/en/services/lung-transplant.html">Learn more about our Lung and Heart-Lung Transplant services ></a></p>

439. At Stanford Children’s, a Young Patient Battles Heart Failure—and Rediscovers Joy in Movement

     Tue, 15 Apr 2025 22:04:33 -0000

     

     After arriving at Stanford Children’s in heart failure, 4-year-old Puuwai was fitted with a VAD, which temporarily impacted his mobility. Now, Puuwai is regaining his strength, one step at a time.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-900x506.jpg" alt="After arriving at Stanford Children’s in heart failure, 4-year-old Puuwai was fitted with a VAD, a device to help support his heart while awaiting a transplant. Although the VAD was crucial for his recovery, it temporarily impacted his mobility. Now, Puuwai is regaining his strength and walking again, one determined step at a time." class="wp-image-27241" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/Untitled-design-2.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p>Puuwai was just 4 years old when he arrived at <a href="http://www.stanfordchildrens.org/">Stanford Medicine Children&#8217;s Health</a> in November 2024. His heart was failing. The medical team in the <a href="https://www.stanfordchildrens.org/en/services/heart-center/services.html">Betty Irene Moore Children’s Heart Center</a> acted quickly, implanting a <a href="https://www.stanfordchildrens.org/en/services/heart-transplant/vad.html">ventricular assist device</a> (VAD), a mechanical pump designed to keep his heart working while he awaited a possible heart transplant.</p> <p>The months that followed were marked by a series of challenges for Puuwai—or “Puu,” as his caregivers affectionately call him. Prolonged sedation, limited mobility and numerous medical procedures left him weak, unable to perform even the simplest movements. But in the midst of a complex medical recovery, Puu began another journey: one of rediscovering how to move, play, and to smile again.</p> <p>Guiding him along that path have been occupational therapist Jen Rivera and physical therapist Leslie Lam, who make up the core of Puu’s <a href="https://www.stanfordchildrens.org/en/services/rehabilitation-services.html">Pediatric Rehabilitation Services</a> team. Their sessions have become a daily ritual of music, movement and small but significant victories.</p> <p>“Witnessing Puu’s bravery as he accepts every challenge we throw his way during our therapy sessions has been an inspiration,” say his therapists. “Our rehab team is honored to be part of his journey.”</p> <p>Puu’s hospital stay has included many procedures with long periods of sedation. The months of inactivity left Puu weakened. But with a regimen carefully tailored to his needs, his care team has helped him regain basic abilities: moving in bed, sitting up, standing, and now, walking with support.</p> <figure class="wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex"> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="675" height="900" data-id="27253" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-675x900.jpg" alt="" class="wp-image-27253" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-675x900.jpg 675w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-338x450.jpg 338w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-768x1024.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-1152x1536.jpg 1152w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-1536x2048.jpg 1536w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/PT.11-scaled.jpg 1920w" sizes="auto, (max-width: 675px) 100vw, 675px" /></figure> </figure> <p>Their sessions have become a celebration of joy and milestones. The Addams Family theme songs—complete with snapping and dancing—opens many of their sessions. There are high-fives, balloon games to celebrate his stuffed animals’ birthdays, and hugs to encourage standing and strengthening. In one breakthrough, Puu sat upright on a tilt table for the first time and exclaimed, “Happy!”</p> <p>What makes Puu’s journey particularly unique is the role his VAD plays. The device is used as a bridge to heart transplant, and his medical team specifically selected it to give him time and the strength to undergo intensive rehabilitation.</p> <p>Now, months into his hospital stay, Puu is no longer just sitting up or standing—<a href="https://www.instagram.com/p/DIfAyonzllT/">he’s cruising the hallways</a> on scooter boards, embarking on scavenger hunts, and flashing his bright smile.  </p> <p>There’s still a long road ahead. But for his family and his care team at Stanford Children&#8217;s, Puu’s courage and progress serve as a powerful reminder of what’s possible.</p>

440. Honoring the Memory of Pat Rice and Claire Fitzgerald

     Thu, 10 Apr 2025 19:29:03 -0000

     

     Their legacy lives on through a book cart, featuring a poem Pat wrote.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Reading cart" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-900x506.jpg" alt="Reading cart" class="wp-image-27192" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p><strong>Pat Rice and Claire Fitzgerald</strong>, beloved husband-and-wife volunteers, spent more than 20 years cuddling NICU babies at Lucile Packard Children&#8217;s Hospital Stanford. Claire offered a gentle, grandmotherly touch, while Pat was known for his soothing Irish tunes. </p> <p>Their legacy lives on through a <strong>book cart created in their honor</strong>, featuring a poem Pat wrote—reminding us all of the power of love and presence in the healing process. </p> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-with-books-1200-900x506.jpg" alt="Cart with books" class="wp-image-27190" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-with-books-1200-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-with-books-1200-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-with-books-1200-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/cart-with-books-1200.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p>“<em>You are so new&#8230; But I know you are strong&#8230; You will create a story even fuller and longer.” – Pat Rice</em></p> <figure class="wp-block-image size-full"><img loading="lazy" decoding="async" width="646" height="391" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2013/12/cuddlers.jpg" alt="" class="wp-image-2859" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2013/12/cuddlers.jpg 646w, https://healthier.stanfordchildrens.org/wp-content/uploads/2013/12/cuddlers-300x181.jpg 300w" sizes="auto, (max-width: 646px) 100vw, 646px" /></figure>

441. The Heart of a Healer: Jacqueline Arroliga’s Extraordinary Journey From Volunteer to Nurse Leader

     Thu, 10 Apr 2025 18:50:05 -0000

     

     What started as a volunteer role at Lucile Packard Children’s Hospital Stanford became a lifelong calling for Jacqueline Arroliga, now a charge nurse in the Maternity Unit.

     <div><img width="768" height="432" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200.jpg" class="attachment-768x768 size-768x768 wp-post-image" alt="Jacqueline Arroliga, Charge Nurse in the Maternity Unit at Lucile Packard Children&#039;s Hospital Stanford" style="margin-bottom: 15px;" decoding="async" loading="lazy" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200.jpg 1200w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-768x432.jpg 768w" sizes="auto, (max-width: 768px) 100vw, 768px" /></div> <figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="900" height="506" src="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-900x506.jpg" alt="Jacqueline Arroliga, Charge Nurse in the Maternity Unit at Lucile Packard Children's Hospital Stanford" class="wp-image-27180" srcset="https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-900x506.jpg 900w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-450x253.jpg 450w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200-768x432.jpg 768w, https://healthier.stanfordchildrens.org/wp-content/uploads/2025/04/jacqueline-1200.jpg 1200w" sizes="auto, (max-width: 900px) 100vw, 900px" /></figure> <p>What started as a volunteer role at <a href="https://www.stanfordchildrens.org/en/lucile-packard-childrens-hospital.html">Lucile Packard Children’s Hospital Stanford</a> became a lifelong calling for Jacqueline Arroliga, now a charge nurse in the <a href="https://www.stanfordchildrens.org/en/services/pregnancy-newborn/maternity-care.html">Maternity Unit</a>. Her story of compassion, perseverance, and dedication proves that even the smallest acts of kindness can shape a career and change lives. When Jacqueline Arroliga first stepped through the doors of Lucile Packard Children’s Hospital in 2009, she didn’t know she was walking into her future. A UC Berkeley graduate with a degree in Molecular Environmental Biology, she was searching for clarity, uncertain whether her path would lead to medical school or nursing.</p> <p>In 2009, she began <a href="https://www.stanfordchildrens.org/en/volunteer.html">volunteering</a> in the Newborn Hearing Program in the Maternity Unit, hoping to get firsthand insight into patient care. The following year, she got her first job at the Information Desk in 2010—but she didn’t stop volunteering. In fact, it was during this time that she transitioned into the Buddy Program, continuing to spend her evenings with pediatric patients after her day shifts at the Info Desk.</p> <p>Her experiences as a Buddy opened her eyes to a side of healthcare she hadn’t expected: many children spent long hours—sometimes days—in the hospital without family at their bedside, not out of neglect but due to life’s circumstances. Parents had other children to care for, jobs to keep, and long distances to travel.</p> <p>One child changed everything for her—a five-year-old boy from the oncology unit. Jacqueline met him through the Buddy Program but also saw him frequently during her Info Desk shifts when he would arrive with his mother. He spoke only Spanish, but the connection they formed was instant. They bonded over card games and simple conversations. One day, he looked up at her and said, “Young lady, go on and paint your nails.” She laughed and promised she would. The next time she saw him, her nails were painted, and he lit up with joy.</p> <p>Later, his mother returned to the hospital alone. She found Jacqueline at the Info Desk, her eyes filled with tears, and thanked her for the time she had spent with her son—because he had passed away. That moment stayed with Jacqueline.</p> <p>“That moment changed me,” she says. “It confirmed everything—I wanted to be the person who<br>brought comfort and care, even in the hardest times.”</p> <p>Determined to follow her heart, Jacqueline enrolled in nursing school at the University of San Francisco. At the same time, she transitioned into a relief position as an Office Assistant in Volunteer Services, helping place and onboard new volunteers while supporting herself through school. She also transitioned her own volunteering to the Cuddler Program, giving comfort to infants when their parents could not be present.</p> <p>“Going to school full-time while working was hard,” she admits, “but I wouldn’t have been able to do it without the help of my amazing manager, Maryellen Brady, who gave me the flexibility I needed.”<br>In 2014, Jacqueline was accepted into the New Grad Program at LPCH and began her professional<br>nursing career in the Maternity Unit—a place she has called home ever since. The early days were<br>challenging. Learning the pace, pressure, and precision of bedside care took everything she had. But she pushed through, leaned on her mentors, and kept showing up with heart and humility.</p> <p>Today, Jacqueline is a clinical nurse IV, one of the charge nurses, co-lead of the Maternity Quality<br>Improvement Committee, and local practice coordinator lead of the Maternity Shared Governance. She is not only a nurse—she is a mentor, an advocate, and a leader deeply committed to her team and her patients.</p> <p>“I’ve seen every level of nursing in my unit, and it’s given me a unique perspective. I want to lead in a<br>way that strengthens my team—where we make decisions together and uplift one another, even on the busiest days.”</p> <p>Looking back, Jacqueline credits every step—every volunteer shift, every office role, every late-night<br>study session—with preparing her for this work.</p> <p>“You never know what someone is going through,” she reflects. “That’s the most valuable lesson I’ve<br>learned. Always lead with kindness.”</p> <p>To those considering volunteering or exploring a career in health care, her advice is clear:<br>“Put yourself in the environment. Experience it firsthand. A shared laugh, a comforting presence, a<br>painted nail—it all matters. It might just change your life, like it did mine.”</p> <p>This <strong>Volunteer Appreciation Week (April 20-27)</strong> and <strong>Nurses Week (May 6-12)</strong>, we honor Jacqueline<br>Arroliga and the countless individuals who dedicate their time, skill, and heart to the care of others.<br>From volunteers who bring warmth into hospital rooms to nurses who walk alongside families in their<br>most vulnerable moments, you are the heartbeat of <a href="https://www.stanfordchildrens.org">Stanford Medicine Children’s Health</a>.</p> <p>Thank you for all that you do.</p> <p><a href="https://www.stanfordchildrens.org/en/volunteer.html"><strong>Learn more about Volunteer Services at Stanford Medicine Children&#8217;s Health &gt;</strong></a></p> <p></p>